Entry Database : PDB / ID : 3v2u Structure visualization Downloads & linksTitle Crystal structure of the yeast GAL regulon complex of the repressor, Gal80p, and the transducer, Gal3p, with galactose and ATP ComponentsGalactose/lactose metabolism regulatory protein GAL80 Protein GAL3 DetailsKeywords TRANSCRIPTION / Rossmann fold / GHMP superfamily / Transcription regulationFunction / homology Function and homology informationFunction Domain/homology Component
regulation of transcription from RNA polymerase II promoter by galactose / galactokinase activity / kinase inhibitor activity / galactose metabolic process / maintenance of protein location / negative regulation of phosphorylation / positive regulation of transcription from RNA polymerase II promoter by galactose / transcription repressor complex / RNA polymerase II-specific DNA-binding transcription factor binding / transcription regulator complex ... regulation of transcription from RNA polymerase II promoter by galactose / galactokinase activity / kinase inhibitor activity / galactose metabolic process / maintenance of protein location / negative regulation of phosphorylation / positive regulation of transcription from RNA polymerase II promoter by galactose / transcription repressor complex / RNA polymerase II-specific DNA-binding transcription factor binding / transcription regulator complex / nucleotide binding / negative regulation of transcription by RNA polymerase II / DNA binding / ATP binding / identical protein binding / nucleus / cytosol / cytoplasm Similarity search - Function de novo design (two linked rop proteins) - #340 / Alpha-Beta Plaits - #3170 / Galactokinase, N-terminal domain / Galactokinase, conserved site / Galactokinase galactose-binding signature / Galactokinase signature. / Galactokinase / Mevalonate/galactokinase / GHMP kinase, C-terminal domain / GHMP kinases C terminal ... de novo design (two linked rop proteins) - #340 / Alpha-Beta Plaits - #3170 / Galactokinase, N-terminal domain / Galactokinase, conserved site / Galactokinase galactose-binding signature / Galactokinase signature. / Galactokinase / Mevalonate/galactokinase / GHMP kinase, C-terminal domain / GHMP kinases C terminal / de novo design (two linked rop proteins) / GHMP kinase N-terminal domain / GHMP kinases N terminal domain / GHMP kinase, C-terminal domain superfamily / Gfo/Idh/MocA-like oxidoreductase, N-terminal / Oxidoreductase family, NAD-binding Rossmann fold / Ribosomal Protein S5; domain 2 - #10 / Dihydrodipicolinate Reductase; domain 2 / Dihydrodipicolinate Reductase; domain 2 / Ribosomal Protein S5; domain 2 / Ribosomal protein S5 domain 2-type fold, subgroup / NAD(P)-binding Rossmann-like Domain / Ribosomal protein S5 domain 2-type fold / Alpha-Beta Plaits / NAD(P)-binding domain superfamily / Up-down Bundle / Rossmann fold / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta Similarity search - Domain/homology ADENOSINE-5'-TRIPHOSPHATE / alpha-D-galactopyranose / Galactose/lactose metabolism regulatory protein GAL80 / Protein GAL3 Similarity search - ComponentBiological species Saccharomyces cerevisiae (brewer's yeast)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.105 Å DetailsAuthors Lavy, T. / Kumar, P.R. / He, H. / Joshua-Tor, L. CitationJournal : Genes Dev. / Year : 2012Title : The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.Authors : Lavy, T. / Kumar, P.R. / He, H. / Joshua-Tor, L. History Deposition Dec 12, 2011 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Feb 8, 2012 Provider : repository / Type : Initial releaseRevision 1.1 Mar 14, 2012 Group : Refinement descriptionRevision 1.2 Mar 21, 2012 Group : Database referencesRevision 1.3 Jul 29, 2020 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Structure summary Category : chem_comp / entity ... chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item : _chem_comp.name / _chem_comp.type ... _chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ref_seq_dif.details Description : Carbohydrate remediation / Provider : repository / Type : RemediationRevision 1.4 Sep 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Refinement description / Structure summary Category : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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