PDB-3u8l: Crystal structure of the acetylcholine binding protein (AChBP) fr...

Basic information

• Entry: Database: PDB / ID: 3u8l
• Title: Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3570 (1-(5-phenylpyridin-3-yl)-1,4-diazepane)
• Components: Acetylcholine-binding protein
• Keywords: Acetylcholine-binding protein/agonist / Lymnaea stagnalis / agonist / Ligand-bindig domain / Acetylcholine / Acetylcholine-binding protein / Acetylcholine-binding protein-agonist complex

Function / homology

Function:

synaptic cleft / extracellular ligand-gated monoatomic ion channel activity / transmembrane signaling receptor activity / synapse / membrane

Domain/homology:

Acetylcholine Binding Protein; Chain: A, / Neurotransmitter-gated ion-channel ligand-binding domain / Neurotransmitter-gated ion-channel / Neurotransmitter-gated ion-channel ligand-binding domain / Neurotransmitter-gated ion-channel ligand-binding domain superfamily / Neurotransmitter-gated ion-channel ligand binding domain / Distorted Sandwich / Ig-like domain profile. / Immunoglobulin-like domain / Mainly Beta

Component:

1-(5-phenylpyridin-3-yl)-1,4-diazepane / Acetylcholine-binding protein

• Biological species: Lymnaea stagnalis (great pond snail)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.32 Å
• Authors: Rohde, L.A.H. / Ahring, P.K. / Jensen, M.L. / Nielsen, E.O. / Peters, D. / Helgstrand, C. / Krintel, C. / Harpsoe, K. / Gajhede, M. / Kastrup, J.S. / Balle, T.
• Citation: Journal: J.Biol.Chem. / Year: 2012; Title: Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed.; Authors: Rohde, L.A. / Ahring, P.K. / Jensen, M.L. / Nielsen, E. / Peters, D. / Helgstrand, C. / Krintel, C. / Harpse, K. / Gajhede, M. / Kastrup, J.S. / Balle, T.

History

Deposition	Oct 17, 2011	Deposition site: RCSB / Processing site: RCSB
Revision 1.0	Dec 14, 2011	Provider: repository / Type: Initial release
Revision 1.1	Sep 18, 2013	Group: Database references
Revision 1.2	Mar 7, 2018	Group: Data collection / Category: diffrn_source / Item: _diffrn_source.pdbx_synchrotron_site
Revision 1.3	Sep 13, 2023	Group: Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Revision 1.4	Oct 30, 2024	Group: Structure summary / Category: pdbx_entry_details / pdbx_modification_feature

Assembly

Deposited unit

A: Acetylcholine-binding protein

B: Acetylcholine-binding protein

C: Acetylcholine-binding protein

D: Acetylcholine-binding protein

E: Acetylcholine-binding protein

F: Acetylcholine-binding protein

G: Acetylcholine-binding protein

H: Acetylcholine-binding protein

I: Acetylcholine-binding protein

J: Acetylcholine-binding protein

hetero molecules

Summary:

• 242 kDa, 10 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	242,460	27
Polymers	238,625	10
Non-polymers	3,835	17
Water	10,791	599

1

A: Acetylcholine-binding protein

B: Acetylcholine-binding protein

C: Acetylcholine-binding protein

D: Acetylcholine-binding protein

E: Acetylcholine-binding protein

hetero molecules

Summary:

• defined by author&software
• 121 kDa, 5 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	121,278	14
Polymers	119,313	5
Non-polymers	1,966	9
Water	90	5

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	14470 Å2
ΔGint	-80 kcal/mol
Surface area	42130 Å2
Method	PISA

2

F: Acetylcholine-binding protein

G: Acetylcholine-binding protein

H: Acetylcholine-binding protein

I: Acetylcholine-binding protein

J: Acetylcholine-binding protein

hetero molecules

Summary:

• defined by author&software
• 121 kDa, 5 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	121,182	13
Polymers	119,313	5
Non-polymers	1,869	8
Water	90	5

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Calculated values:

Buried area	14220 Å2
ΔGint	-62 kcal/mol
Surface area	42190 Å2
Method	PISA

Unit cell

Length a, b, c (Å)	73.960, 114.810, 127.060
Angle α, β, γ (deg.)	90.00, 91.08, 90.00
Int Tables number	4
Space group name H-M	P1211

Noncrystallographic symmetry (NCS)

NCS domain:

ID	Ens-ID
1	1
2	1
3	1
4	1
5	1
6	1
7	1
8	1
9	1
10	1
1	2
2	2
3	2
4	2
5	2
6	2
7	2
8	2
9	2
10	2
1	3
2	3
3	3
4	3
5	3
6	3
7	3
8	3
9	3
10	3
1	4
2	4
3	4
4	4
5	4
6	4
7	4
8	4
9	4
10	4
1	5
2	5
3	5
4	5
5	5
6	5
7	5
8	5
1	6
2	6
3	6
4	6
5	6
6	6
7	6
8	6
9	6
10	6
1	7
2	7
3	7
4	7
5	7
6	7
7	7
8	7
9	7
10	7
1	8
2	8
3	8
4	8
5	8
6	8
7	8
8	8
9	8
10	8
1	9
2	9
3	9
4	9
5	9
6	9
7	9
8	9
9	9
10	9
1	10
2	10
3	10
4	10
5	10
6	10
7	10
8	10
9	10
10	10
1	11
2	11
3	11
4	11
5	11
6	11
7	11
8	11
9	11
10	11
1	12
2	12
3	12
4	12
5	12
6	12
7	12
8	12
9	12
10	12
1	13
2	13
3	13
4	13
5	13
6	13
7	13
8	13
9	13
10	13
1	14
2	14
3	14
4	14
5	14
6	14
7	14
8	14
9	14
10	14
1	15
2	15
3	15
4	15
5	15
6	15
7	15
8	15
9	15
10	15
1	16
2	16
3	16
4	16
5	16
6	16
7	16
8	16
9	16
10	16
1	17
2	17
3	17
4	17
5	17
6	17
7	17
8	17
9	17
10	17
1	18
2	18
3	18
4	18
5	18
6	18
7	18
8	18
9	18
10	18
1	19
2	19
3	19
4	19
5	19
6	19
7	19
8	19
9	19
10	19
1	20
2	20
3	20
4	20
5	20
6	20
7	20
8	20
9	20
10	20

NCS domain segments:

Dom-ID	Component-ID	Ens-ID	Selection details
1	1	1	chain A and resid 1:11
2	1	1	chain B and resid 1:11
3	1	1	chain C and resid 1:11
4	1	1	chain D and resid 1:11
5	1	1	chain E and resid 1:11
6	1	1	chain F and resid 1:11
7	1	1	chain G and resid 1:11
8	1	1	chain H and resid 1:11
9	1	1	chain I and resid 1:11
10	1	1	chain J and resid 1:11
1	1	2	chain A and resid 16:20
2	1	2	chain B and resid 16:20
3	1	2	chain C and resid 16:20
4	1	2	chain D and resid 16:20
5	1	2	chain E and resid 16:20
6	1	2	chain F and resid 16:20
7	1	2	chain G and resid 16:20
8	1	2	chain H and resid 16:20
9	1	2	chain I and resid 16:20
10	1	2	chain J and resid 16:20
1	1	3	chain A and resid 26:30
2	1	3	chain B and resid 26:30
3	1	3	chain C and resid 26:30
4	1	3	chain D and resid 26:30
5	1	3	chain E and resid 26:30
6	1	3	chain F and resid 26:30
7	1	3	chain G and resid 26:30
8	1	3	chain H and resid 26:30
9	1	3	chain I and resid 26:30
10	1	3	chain J and resid 26:30
1	1	4	chain A and resid 33:42
2	1	4	chain B and resid 33:42
3	1	4	chain C and resid 33:42
4	1	4	chain D and resid 33:42
5	1	4	chain E and resid 33:42
6	1	4	chain F and resid 33:42
7	1	4	chain G and resid 33:42
8	1	4	chain H and resid 33:42
9	1	4	chain I and resid 33:42
10	1	4	chain J and resid 33:42
1	1	5	chain A and resid 43
2	1	5	chain B and resid 43
3	1	5	chain C and resid 43
4	1	5	chain E and resid 43
5	1	5	chain F and resid 43
6	1	5	chain G and resid 43
7	1	5	chain H and resid 43
8	1	5	chain J and resid 43
1	1	6	chain A and resid 45:49
2	1	6	chain B and resid 45:49
3	1	6	chain C and resid 45:49
4	1	6	chain D and resid 45:49
5	1	6	chain E and resid 45:49
6	1	6	chain F and resid 45:49
7	1	6	chain G and resid 45:49
8	1	6	chain H and resid 45:49
9	1	6	chain I and resid 45:49
10	1	6	chain J and resid 45:49
1	1	7	chain A and resid 51:52
2	1	7	chain B and resid 51:52
3	1	7	chain C and resid 51:52
4	1	7	chain D and resid 51:52
5	1	7	chain E and resid 51:52
6	1	7	chain F and resid 51:52
7	1	7	chain G and resid 51:52
8	1	7	chain H and resid 51:52
9	1	7	chain I and resid 51:52
10	1	7	chain J and resid 51:52
1	1	8	chain A and resid 56:82
2	1	8	chain B and resid 56:82
3	1	8	chain C and resid 56:82
4	1	8	chain D and resid 56:82
5	1	8	chain E and resid 56:82
6	1	8	chain F and resid 56:82
7	1	8	chain G and resid 56:82
8	1	8	chain H and resid 56:82
9	1	8	chain I and resid 56:82
10	1	8	chain J and resid 56:82
1	1	9	chain A and resid 84:100
2	1	9	chain B and resid 84:100
3	1	9	chain C and resid 84:100
4	1	9	chain D and resid 84:100
5	1	9	chain E and resid 84:100
6	1	9	chain F and resid 84:100
7	1	9	chain G and resid 84:100
8	1	9	chain H and resid 84:100
9	1	9	chain I and resid 84:100
10	1	9	chain J and resid 84:100
1	1	10	chain A and resid 102:109
2	1	10	chain B and resid 102:109
3	1	10	chain C and resid 102:109
4	1	10	chain D and resid 102:109
5	1	10	chain E and resid 102:109
6	1	10	chain F and resid 102:109
7	1	10	chain G and resid 102:109
8	1	10	chain H and resid 102:109
9	1	10	chain I and resid 102:109
10	1	10	chain J and resid 102:109
1	1	11	chain A and resid 111:113
2	1	11	chain B and resid 111:113
3	1	11	chain C and resid 111:113
4	1	11	chain D and resid 111:113
5	1	11	chain E and resid 111:113
6	1	11	chain F and resid 111:113
7	1	11	chain G and resid 111:113
8	1	11	chain H and resid 111:113
9	1	11	chain I and resid 111:113
10	1	11	chain J and resid 111:113
1	1	12	chain A and resid 115:119
2	1	12	chain B and resid 115:119
3	1	12	chain C and resid 115:119
4	1	12	chain D and resid 115:119
5	1	12	chain E and resid 115:119
6	1	12	chain F and resid 115:119
7	1	12	chain G and resid 115:119
8	1	12	chain H and resid 115:119
9	1	12	chain I and resid 115:119
10	1	12	chain J and resid 115:119
1	1	13	chain A and resid 121:128
2	1	13	chain B and resid 121:128
3	1	13	chain C and resid 121:128
4	1	13	chain D and resid 121:128
5	1	13	chain E and resid 121:128
6	1	13	chain F and resid 121:128
7	1	13	chain G and resid 121:128
8	1	13	chain H and resid 121:128
9	1	13	chain I and resid 121:128
10	1	13	chain J and resid 121:128
1	1	14	chain A and resid 133:136
2	1	14	chain B and resid 133:136
3	1	14	chain C and resid 133:136
4	1	14	chain D and resid 133:136
5	1	14	chain E and resid 133:136
6	1	14	chain F and resid 133:136
7	1	14	chain G and resid 133:136
8	1	14	chain H and resid 133:136
9	1	14	chain I and resid 133:136
10	1	14	chain J and resid 133:136
1	1	15	chain A and resid 140:145
2	1	15	chain B and resid 140:145
3	1	15	chain C and resid 140:145
4	1	15	chain D and resid 140:145
5	1	15	chain E and resid 140:145
6	1	15	chain F and resid 140:145
7	1	15	chain G and resid 140:145
8	1	15	chain H and resid 140:145
9	1	15	chain I and resid 140:145
10	1	15	chain J and resid 140:145
1	1	16	chain A and resid 147:152
2	1	16	chain B and resid 147:152
3	1	16	chain C and resid 147:152
4	1	16	chain D and resid 147:152
5	1	16	chain E and resid 147:152
6	1	16	chain F and resid 147:152
7	1	16	chain G and resid 147:152
8	1	16	chain H and resid 147:152
9	1	16	chain I and resid 147:152
10	1	16	chain J and resid 147:152
1	1	17	chain A and resid 164:169
2	1	17	chain B and resid 164:169
3	1	17	chain C and resid 164:169
4	1	17	chain D and resid 164:169
5	1	17	chain E and resid 164:169
6	1	17	chain F and resid 164:169
7	1	17	chain G and resid 164:169
8	1	17	chain H and resid 164:169
9	1	17	chain I and resid 164:169
10	1	17	chain J and resid 164:169
1	1	18	chain A and resid 171:177
2	1	18	chain B and resid 171:177
3	1	18	chain C and resid 171:177
4	1	18	chain D and resid 171:177
5	1	18	chain E and resid 171:177
6	1	18	chain F and resid 171:177
7	1	18	chain G and resid 171:177
8	1	18	chain H and resid 171:177
9	1	18	chain I and resid 171:177
10	1	18	chain J and resid 171:177
1	1	19	chain A and resid 191:195
2	1	19	chain B and resid 191:195
3	1	19	chain C and resid 191:195
4	1	19	chain D and resid 191:195
5	1	19	chain E and resid 191:195
6	1	19	chain F and resid 191:195
7	1	19	chain G and resid 191:195
8	1	19	chain H and resid 191:195
9	1	19	chain I and resid 191:195
10	1	19	chain J and resid 191:195
1	1	20	chain A and resid 197:203
2	1	20	chain B and resid 197:203
3	1	20	chain C and resid 197:203
4	1	20	chain D and resid 197:203
5	1	20	chain E and resid 197:203
6	1	20	chain F and resid 197:203
7	1	20	chain G and resid 197:203
8	1	20	chain H and resid 197:203
9	1	20	chain I and resid 197:203
10	1	20	chain J and resid 197:203

NCS ensembles :

ID
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20

Components

#1: Protein

A B C D E F G H I J
Acetylcholine-binding protein / ACh-binding protein / AchBP

Details:

Mass: 23862.523 Da / Num. of mol.: 10
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Lymnaea stagnalis (great pond snail) / Production host: Spodoptera frugiperda (fall armyworm) / Strain (production host): Sf9 / Keywords: Acetylcholine-binding protein / References: UniProt: P58154

#2: Chemical

A-211 B-211 B-212 B-213 C-211 D-211 E-211 F-211 G-211 H-211 H-212 H-213 I-211 J-211
ChemComp-09Q / 1-(5-phenylpyridin-3-yl)-1,4-diazepane

Details:

Mass: 253.342 Da / Num. of mol.: 14 / Source method: obtained synthetically / Formula: C₁₆H₁₉N₃

#3: Chemical

B-214 B-215 G-212 ChemComp-SO4 / SULFATE ION

Details:

Mass: 96.063 Da / Num. of mol.: 3 / Source method: obtained synthetically / Formula: SO₄

#4: Water

ChemComp-HOH / water

Details:

Mass: 18.015 Da / Num. of mol.: 599 / Source method: isolated from a natural source / Formula: H₂O

• Has protein modification: Y

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.26 ų/Da / Density % sol: 45.58 %
• Crystal grow: Temperature: 293 K / Method: vapor diffusion, hanging drop / pH: 8 ; Details: 50mM Tris, 1.5M Ammonium sulfate, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: MAX II / Beamline: I911-3 / Wavelength: 0.9 Å
• Detector: Type: MARMOSAIC 225 mm CCD / Detector: CCD / Date: Jun 18, 2010
• Radiation: Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Wavelength: 0.9 Å / Relative weight: 1
• Reflection: Resolution: 2.32→44.78 Å / Num. all: 88377 / Num. obs: 88355 / % possible obs: 100 % / Redundancy: 4.1 % / B_iso Wilson estimate: 24.2 Ų / R_merge(I) obs: 0.099 / R_sym value: 0.099 / Net I/σ(I): 9.4

Reflection shell

Diffraction-ID: 1

Resolution (Å)	Redundancy (%)	Rmerge(I) obs	Mean I/σ(I) obs	Num. unique all	Rsym value	% possible all
2.35-2.48	4	0.362	2.1	12876	0.362	100
2.48-2.63	4	0.29	4.6	12142	0.29	100
2.63-2.81	4.1	0.225	5.8	11433	0.225	100
2.81-3.03	4.1	0.158	7.9	10656	0.158	99.9
3.03-3.32	4.1	0.103	11.6	9792	0.103	100
3.32-3.72	4.1	0.071	15.3	8915	0.071	100
3.72-4.29	4.2	0.056	19.3	7836	0.056	100
4.29-5.25	4.2	0.058	21.7	6666	0.058	100
5.25-7.43	4.1	0.058	20.6	5166	0.058	100
7.43-44.78	4	0.041	24.2	2873	0.041	99.5

Processing

Software

Name	Version	Classification
PHASER		phasing
PHENIX	(phenix.refine: 1.6.4_486)	refinement
MOSFLM		data reduction
SCALA		data scaling

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: PDB entry 1UW6: pentamer, chain A-E

1uw6

Resolution: 2.32→42.346 Å / SU ML: 0.3 / Isotropic thermal model: Restrained / Cross valid method: Troughout / σ(F): 0 / Phase error: 22.97 / Stereochemistry target values: MLHL

	Rfactor	Num. reflection	% reflection	Selection details
Rfree	0.2441	4595	5.01 %	Random
Rwork	0.1906	-	-	-
obs	0.1932	88355	99.94 %	-

• Solvent computation: Shrinkage radii: 0.95 Å / VDW probe radii: 1.2 Å / Solvent model: FLAT BULK SOLVENT MODEL / B_sol: 21.018 Ų / k_sol: 0.356 e/ų

Displacement parameters

B_iso mean: 29.4 Ų

	Baniso -1	Baniso -2	Baniso -3
1-	8.1034 Å2	-0 Å2	-1.4582 Å2
2-	-	-6.1611 Å2	-0 Å2
3-	-	-	-1.9422 Å2

Refinement step

Cycle: LAST / Resolution: 2.32→42.346 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	16137	0	281	599	17017

Refine LS restraints

Refine-ID	Type	Dev ideal	Number
X-RAY DIFFRACTION	f_bond_d	0.007	16874
X-RAY DIFFRACTION	f_angle_d	1.061	22980
X-RAY DIFFRACTION	f_dihedral_angle_d	14.466	6242
X-RAY DIFFRACTION	f_chiral_restr	0.07	2584
X-RAY DIFFRACTION	f_plane_restr	0.005	2960

Refine LS restraints NCS

Ens-ID	Dom-ID	Auth asym-ID	Number	Refine-ID	Type	Rms dev position (Å)
1	1	A	95	X-RAY DIFFRACTION	POSITIONAL
1	2	B	95	X-RAY DIFFRACTION	POSITIONAL	0.032
1	3	C	95	X-RAY DIFFRACTION	POSITIONAL	0.028
1	4	D	95	X-RAY DIFFRACTION	POSITIONAL	0.029
1	5	E	95	X-RAY DIFFRACTION	POSITIONAL	0.031
1	6	F	95	X-RAY DIFFRACTION	POSITIONAL	0.031
1	7	G	95	X-RAY DIFFRACTION	POSITIONAL	0.03
1	8	H	95	X-RAY DIFFRACTION	POSITIONAL	0.031
1	9	I	95	X-RAY DIFFRACTION	POSITIONAL	0.028
1	10	J	95	X-RAY DIFFRACTION	POSITIONAL	0.033
2	1	A	37	X-RAY DIFFRACTION	POSITIONAL
2	2	B	37	X-RAY DIFFRACTION	POSITIONAL	0.026
2	3	C	37	X-RAY DIFFRACTION	POSITIONAL	0.032
2	4	D	37	X-RAY DIFFRACTION	POSITIONAL	0.038
2	5	E	37	X-RAY DIFFRACTION	POSITIONAL	0.03
2	6	F	37	X-RAY DIFFRACTION	POSITIONAL	0.027
2	7	G	37	X-RAY DIFFRACTION	POSITIONAL	0.027
2	8	H	37	X-RAY DIFFRACTION	POSITIONAL	0.027
2	9	I	37	X-RAY DIFFRACTION	POSITIONAL	0.029
2	10	J	37	X-RAY DIFFRACTION	POSITIONAL	0.037
3	1	A	32	X-RAY DIFFRACTION	POSITIONAL
3	2	B	32	X-RAY DIFFRACTION	POSITIONAL	0.038
3	3	C	32	X-RAY DIFFRACTION	POSITIONAL	0.045
3	4	D	32	X-RAY DIFFRACTION	POSITIONAL	0.041
3	5	E	32	X-RAY DIFFRACTION	POSITIONAL	0.038
3	6	F	32	X-RAY DIFFRACTION	POSITIONAL	0.03
3	7	G	32	X-RAY DIFFRACTION	POSITIONAL	0.035
3	8	H	32	X-RAY DIFFRACTION	POSITIONAL	0.038
3	9	I	32	X-RAY DIFFRACTION	POSITIONAL	0.034
3	10	J	32	X-RAY DIFFRACTION	POSITIONAL	0.033
4	1	A	84	X-RAY DIFFRACTION	POSITIONAL
4	2	B	84	X-RAY DIFFRACTION	POSITIONAL	0.035
4	3	C	84	X-RAY DIFFRACTION	POSITIONAL	0.041
4	4	D	84	X-RAY DIFFRACTION	POSITIONAL	0.047
4	5	E	84	X-RAY DIFFRACTION	POSITIONAL	0.041
4	6	F	84	X-RAY DIFFRACTION	POSITIONAL	0.033
4	7	G	84	X-RAY DIFFRACTION	POSITIONAL	0.036
4	8	H	84	X-RAY DIFFRACTION	POSITIONAL	0.038
4	9	I	84	X-RAY DIFFRACTION	POSITIONAL	0.048
4	10	J	84	X-RAY DIFFRACTION	POSITIONAL	0.043
5	1	A	9	X-RAY DIFFRACTION	POSITIONAL
5	2	B	9	X-RAY DIFFRACTION	POSITIONAL	0.032
5	3	C	9	X-RAY DIFFRACTION	POSITIONAL	0.034
5	4	E	9	X-RAY DIFFRACTION	POSITIONAL	0.035
5	5	F	9	X-RAY DIFFRACTION	POSITIONAL	0.022
5	6	G	9	X-RAY DIFFRACTION	POSITIONAL	0.027
5	7	H	9	X-RAY DIFFRACTION	POSITIONAL	0.03
5	8	J	9	X-RAY DIFFRACTION	POSITIONAL	0.036
6	1	A	39	X-RAY DIFFRACTION	POSITIONAL
6	2	B	39	X-RAY DIFFRACTION	POSITIONAL	0.03
6	3	C	39	X-RAY DIFFRACTION	POSITIONAL	0.037
6	4	D	39	X-RAY DIFFRACTION	POSITIONAL	0.045
6	5	E	39	X-RAY DIFFRACTION	POSITIONAL	0.032
6	6	F	39	X-RAY DIFFRACTION	POSITIONAL	0.03
6	7	G	39	X-RAY DIFFRACTION	POSITIONAL	0.027
6	8	H	39	X-RAY DIFFRACTION	POSITIONAL	0.034
6	9	I	39	X-RAY DIFFRACTION	POSITIONAL	0.052
6	10	J	39	X-RAY DIFFRACTION	POSITIONAL	0.028
7	1	A	18	X-RAY DIFFRACTION	POSITIONAL
7	2	B	18	X-RAY DIFFRACTION	POSITIONAL	0.033
7	3	C	18	X-RAY DIFFRACTION	POSITIONAL	0.033
7	4	D	18	X-RAY DIFFRACTION	POSITIONAL	0.026
7	5	E	18	X-RAY DIFFRACTION	POSITIONAL	0.03
7	6	F	18	X-RAY DIFFRACTION	POSITIONAL	0.027
7	7	G	18	X-RAY DIFFRACTION	POSITIONAL	0.029
7	8	H	18	X-RAY DIFFRACTION	POSITIONAL	0.031
7	9	I	18	X-RAY DIFFRACTION	POSITIONAL	0.034
7	10	J	18	X-RAY DIFFRACTION	POSITIONAL	0.03
8	1	A	216	X-RAY DIFFRACTION	POSITIONAL
8	2	B	216	X-RAY DIFFRACTION	POSITIONAL	0.036
8	3	C	216	X-RAY DIFFRACTION	POSITIONAL	0.04
8	4	D	216	X-RAY DIFFRACTION	POSITIONAL	0.044
8	5	E	216	X-RAY DIFFRACTION	POSITIONAL	0.034
8	6	F	216	X-RAY DIFFRACTION	POSITIONAL	0.029
8	7	G	216	X-RAY DIFFRACTION	POSITIONAL	0.035
8	8	H	216	X-RAY DIFFRACTION	POSITIONAL	0.043
8	9	I	216	X-RAY DIFFRACTION	POSITIONAL	0.034
8	10	J	216	X-RAY DIFFRACTION	POSITIONAL	0.037
9	1	A	126	X-RAY DIFFRACTION	POSITIONAL
9	2	B	126	X-RAY DIFFRACTION	POSITIONAL	0.041
9	3	C	126	X-RAY DIFFRACTION	POSITIONAL	0.049
9	4	D	126	X-RAY DIFFRACTION	POSITIONAL	0.048
9	5	E	126	X-RAY DIFFRACTION	POSITIONAL	0.047
9	6	F	126	X-RAY DIFFRACTION	POSITIONAL	0.037
9	7	G	126	X-RAY DIFFRACTION	POSITIONAL	0.046
9	8	H	126	X-RAY DIFFRACTION	POSITIONAL	0.042
9	9	I	126	X-RAY DIFFRACTION	POSITIONAL	0.045
9	10	J	126	X-RAY DIFFRACTION	POSITIONAL	0.044
10	1	A	56	X-RAY DIFFRACTION	POSITIONAL
10	2	B	56	X-RAY DIFFRACTION	POSITIONAL	0.034
10	3	C	56	X-RAY DIFFRACTION	POSITIONAL	0.039
10	4	D	56	X-RAY DIFFRACTION	POSITIONAL	0.041
10	5	E	56	X-RAY DIFFRACTION	POSITIONAL	0.04
10	6	F	56	X-RAY DIFFRACTION	POSITIONAL	0.037
10	7	G	56	X-RAY DIFFRACTION	POSITIONAL	0.037
10	8	H	56	X-RAY DIFFRACTION	POSITIONAL	0.035
10	9	I	56	X-RAY DIFFRACTION	POSITIONAL	0.042
10	10	J	56	X-RAY DIFFRACTION	POSITIONAL	0.04
11	1	A	27	X-RAY DIFFRACTION	POSITIONAL
11	2	B	27	X-RAY DIFFRACTION	POSITIONAL	0.031
11	3	C	27	X-RAY DIFFRACTION	POSITIONAL	0.045
11	4	D	27	X-RAY DIFFRACTION	POSITIONAL	0.045
11	5	E	27	X-RAY DIFFRACTION	POSITIONAL	0.044
11	6	F	27	X-RAY DIFFRACTION	POSITIONAL	0.033
11	7	G	27	X-RAY DIFFRACTION	POSITIONAL	0.039
11	8	H	27	X-RAY DIFFRACTION	POSITIONAL	0.037
11	9	I	27	X-RAY DIFFRACTION	POSITIONAL	0.026
11	10	J	27	X-RAY DIFFRACTION	POSITIONAL	0.047
12	1	A	41	X-RAY DIFFRACTION	POSITIONAL
12	2	B	41	X-RAY DIFFRACTION	POSITIONAL	0.044
12	3	C	41	X-RAY DIFFRACTION	POSITIONAL	0.035
12	4	D	41	X-RAY DIFFRACTION	POSITIONAL	0.037
12	5	E	41	X-RAY DIFFRACTION	POSITIONAL	0.037
12	6	F	41	X-RAY DIFFRACTION	POSITIONAL	0.034
12	7	G	41	X-RAY DIFFRACTION	POSITIONAL	0.036
12	8	H	41	X-RAY DIFFRACTION	POSITIONAL	0.034
12	9	I	41	X-RAY DIFFRACTION	POSITIONAL	0.042
12	10	J	41	X-RAY DIFFRACTION	POSITIONAL	0.036
13	1	A	55	X-RAY DIFFRACTION	POSITIONAL
13	2	B	55	X-RAY DIFFRACTION	POSITIONAL	0.035
13	3	C	55	X-RAY DIFFRACTION	POSITIONAL	0.035
13	4	D	55	X-RAY DIFFRACTION	POSITIONAL	0.034
13	5	E	55	X-RAY DIFFRACTION	POSITIONAL	0.037
13	6	F	55	X-RAY DIFFRACTION	POSITIONAL	0.031
13	7	G	55	X-RAY DIFFRACTION	POSITIONAL	0.036
13	8	H	55	X-RAY DIFFRACTION	POSITIONAL	0.032
13	9	I	55	X-RAY DIFFRACTION	POSITIONAL	0.042
13	10	J	55	X-RAY DIFFRACTION	POSITIONAL	0.031
14	1	A	22	X-RAY DIFFRACTION	POSITIONAL
14	2	B	22	X-RAY DIFFRACTION	POSITIONAL	0.029
14	3	C	22	X-RAY DIFFRACTION	POSITIONAL	0.035
14	4	D	22	X-RAY DIFFRACTION	POSITIONAL	0.029
14	5	E	22	X-RAY DIFFRACTION	POSITIONAL	0.038
14	6	F	22	X-RAY DIFFRACTION	POSITIONAL	0.019
14	7	G	22	X-RAY DIFFRACTION	POSITIONAL	0.039
14	8	H	22	X-RAY DIFFRACTION	POSITIONAL	0.028
14	9	I	22	X-RAY DIFFRACTION	POSITIONAL	0.033
14	10	J	22	X-RAY DIFFRACTION	POSITIONAL	0.045
15	1	A	49	X-RAY DIFFRACTION	POSITIONAL
15	2	B	49	X-RAY DIFFRACTION	POSITIONAL	0.039
15	3	C	49	X-RAY DIFFRACTION	POSITIONAL	0.044
15	4	D	49	X-RAY DIFFRACTION	POSITIONAL	0.041
15	5	E	49	X-RAY DIFFRACTION	POSITIONAL	0.031
15	6	F	49	X-RAY DIFFRACTION	POSITIONAL	0.041
15	7	G	49	X-RAY DIFFRACTION	POSITIONAL	0.042
15	8	H	49	X-RAY DIFFRACTION	POSITIONAL	0.041
15	9	I	49	X-RAY DIFFRACTION	POSITIONAL	0.036
15	10	J	49	X-RAY DIFFRACTION	POSITIONAL	0.043
16	1	A	47	X-RAY DIFFRACTION	POSITIONAL
16	2	B	47	X-RAY DIFFRACTION	POSITIONAL	0.045
16	3	C	47	X-RAY DIFFRACTION	POSITIONAL	0.045
16	4	D	47	X-RAY DIFFRACTION	POSITIONAL	0.038
16	5	E	47	X-RAY DIFFRACTION	POSITIONAL	0.044
16	6	F	47	X-RAY DIFFRACTION	POSITIONAL	0.033
16	7	G	47	X-RAY DIFFRACTION	POSITIONAL	0.031
16	8	H	47	X-RAY DIFFRACTION	POSITIONAL	0.038
16	9	I	47	X-RAY DIFFRACTION	POSITIONAL	0.038
16	10	J	47	X-RAY DIFFRACTION	POSITIONAL	0.048
17	1	A	56	X-RAY DIFFRACTION	POSITIONAL
17	2	B	56	X-RAY DIFFRACTION	POSITIONAL	0.047
17	3	C	56	X-RAY DIFFRACTION	POSITIONAL	0.03
17	4	D	56	X-RAY DIFFRACTION	POSITIONAL	0.035
17	5	E	56	X-RAY DIFFRACTION	POSITIONAL	0.028
17	6	F	56	X-RAY DIFFRACTION	POSITIONAL	0.026
17	7	G	56	X-RAY DIFFRACTION	POSITIONAL	0.035
17	8	H	56	X-RAY DIFFRACTION	POSITIONAL	0.033
17	9	I	56	X-RAY DIFFRACTION	POSITIONAL	0.027
17	10	J	56	X-RAY DIFFRACTION	POSITIONAL	0.033
18	1	A	58	X-RAY DIFFRACTION	POSITIONAL
18	2	B	58	X-RAY DIFFRACTION	POSITIONAL	0.032
18	3	C	58	X-RAY DIFFRACTION	POSITIONAL	0.032
18	4	D	58	X-RAY DIFFRACTION	POSITIONAL	0.034
18	5	E	58	X-RAY DIFFRACTION	POSITIONAL	0.035
18	6	F	58	X-RAY DIFFRACTION	POSITIONAL	0.029
18	7	G	58	X-RAY DIFFRACTION	POSITIONAL	0.034
18	8	H	58	X-RAY DIFFRACTION	POSITIONAL	0.034
18	9	I	58	X-RAY DIFFRACTION	POSITIONAL	0.031
18	10	J	58	X-RAY DIFFRACTION	POSITIONAL	0.039
19	1	A	41	X-RAY DIFFRACTION	POSITIONAL
19	2	B	41	X-RAY DIFFRACTION	POSITIONAL	0.038
19	3	C	41	X-RAY DIFFRACTION	POSITIONAL	0.032
19	4	D	41	X-RAY DIFFRACTION	POSITIONAL	0.033
19	5	E	41	X-RAY DIFFRACTION	POSITIONAL	0.033
19	6	F	41	X-RAY DIFFRACTION	POSITIONAL	0.031
19	7	G	41	X-RAY DIFFRACTION	POSITIONAL	0.036
19	8	H	41	X-RAY DIFFRACTION	POSITIONAL	0.033
19	9	I	41	X-RAY DIFFRACTION	POSITIONAL	0.032
19	10	J	41	X-RAY DIFFRACTION	POSITIONAL	0.045
20	1	A	60	X-RAY DIFFRACTION	POSITIONAL
20	2	B	60	X-RAY DIFFRACTION	POSITIONAL	0.031
20	3	C	60	X-RAY DIFFRACTION	POSITIONAL	0.032
20	4	D	60	X-RAY DIFFRACTION	POSITIONAL	0.034
20	5	E	60	X-RAY DIFFRACTION	POSITIONAL	0.032
20	6	F	60	X-RAY DIFFRACTION	POSITIONAL	0.027
20	7	G	60	X-RAY DIFFRACTION	POSITIONAL	0.037
20	8	H	60	X-RAY DIFFRACTION	POSITIONAL	0.038
20	9	I	60	X-RAY DIFFRACTION	POSITIONAL	0.036
20	10	J	60	X-RAY DIFFRACTION	POSITIONAL	0.032

LS refinement shell

Refine-ID: X-RAY DIFFRACTION

Resolution (Å)	Rfactor Rfree	Num. reflection Rfree	Rfactor Rwork	Num. reflection Rwork	Num. reflection obs	% reflection obs (%)
2.32-2.3464	0.304	122	0.2373	2880	2881	100
2.3464-2.374	0.2986	151	0.2348	2898	2899	100
2.374-2.4029	0.2898	162	0.23	2894	2895	100
2.4029-2.4333	0.301	147	0.2267	2893	2893	100
2.4333-2.4653	0.2808	138	0.2283	2922	2923	100
2.4653-2.4991	0.2841	157	0.2303	2877	2878	100
2.4991-2.5348	0.2956	137	0.2146	2905	2905	100
2.5348-2.5726	0.2855	158	0.2094	2861	2862	100
2.5726-2.6128	0.311	159	0.2127	2908	2907	100
2.6128-2.6557	0.2596	157	0.2127	2908	2910	100
2.6557-2.7015	0.266	154	0.2034	2868	2868	100
2.7015-2.7506	0.2748	161	0.1932	2907	2907	100
2.7506-2.8035	0.2362	158	0.2032	2903	2903	100
2.8035-2.8607	0.2928	157	0.2065	2872	2874	100
2.8607-2.9229	0.2535	145	0.1904	2887	2885	100
2.9229-2.9908	0.239	155	0.193	2911	2911	100
2.9908-3.0656	0.2644	155	0.2021	2897	2902	100
3.0656-3.1485	0.2679	159	0.2009	2875	2872	100
3.1485-3.2411	0.2437	158	0.1937	2928	2927	100
3.2411-3.3457	0.2424	127	0.1873	2939	2940	100
3.3457-3.4652	0.2284	156	0.1751	2883	2882	100
3.4652-3.6039	0.2261	166	0.1675	2905	2906	100
3.6039-3.7678	0.2233	172	0.1712	2877	2875	100
3.7678-3.9663	0.2178	169	0.1723	2911	2912	100
3.9663-4.2146	0.2132	157	0.1578	2906	2908	100
4.2146-4.5396	0.2038	155	0.1453	2934	2932	100
4.5396-4.9958	0.1984	156	0.1531	2916	2916	100
4.9958-5.7172	0.2429	136	0.1839	2960	2961	100
5.7172-7.1974	0.2322	161	0.2296	2931	2932	100
7.1974-42.3528	0.2231	150	0.2082	2974	2996	99

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	0.9705	-0.2804	-0.5655	1.1677	-0.9074	5.0837	-0.2713	0.0242	0.2786	0.0657	-0.1482	-0.1342	-1.6032	0.6827	-0.045	0.1234	-0.0365	-0.0199	0.252	0.1013	0.2958	17.6847	41.7722	12.074
2	0.2559	0.0164	-0.3164	0.8061	-0.0954	0.6522	-0.0547	0.6788	1.02	-0.2205	-0.096	0.3087	-0.3402	0.36	0.0005	0.2229	0.0153	0.0064	0.2081	0.069	0.3288	-1.3556	44.0697	27.1338
3	0.5972	0.1192	0.2593	1.2263	-0.3156	0.3071	-0.4034	0.1345	0.0192	-0.2726	0.2322	0.25	-0.3058	-0.1832	-0	0.2471	-0.0292	-0.0656	0.1783	0.0129	0.3121	7.0728	48.3453	49.1805
4	0.674	0.1719	-0.4035	0.6135	-0.2361	0.7666	-0.2333	-0.1565	0.199	0.064	-0.2673	0.3308	-0.9713	-0.1176	-0.0035	0.2712	-0.0544	-0.0095	0.1785	0.0411	0.247	31.3045	48.7734	47.6565
5	1.7424	-0.5371	-0.4712	0.622	-0.0405	1.2317	0.2519	-0.2708	0.5281	0.0837	-0.0576	-0.2141	-0.2329	0.2775	0.0143	0.2928	-0.0423	-0.0202	0.0888	0.0422	0.1927	37.9102	44.6469	24.9965
6	0.5317	0.276	0.6169	0.9671	0.6294	1.0555	0.2668	0.4296	0.1239	0.8562	-0.3048	0.1398	1.2205	0.4657	0.0176	0.3153	-0.0132	0.0474	0.2221	0.0488	0.2064	22.11	57.7225	50.4584
7	0.3495	-0.2433	0.0614	0.6007	-0.0737	0.8264	-0.1478	-0.4805	-0.417	0.4019	0.0887	-0.1579	-0.5491	0.3491	0.0035	0.2363	0.0034	-0.0018	0.142	0.0564	0.2282	0.2379	55.6321	40.6978
8	0.5519	0.0105	-0.3354	0.8283	-0.0405	0.3227	0.1807	-0.005	-0.796	-0.1518	-0.064	0.0592	0.565	-0.2598	0.0002	0.2756	-0.0408	-0.0082	0.1898	0.0219	0.3537	3.523	51.4411	16.9208
9	0.6268	0.1914	0.5572	1.0512	0.4106	1.0062	0.2248	0.0829	-0.6782	0.5138	0.3934	0.3512	1.2124	-0.0136	-0.0043	0.2132	0.0287	-0.0463	0.1631	0.0416	0.3712	27.359	51.0521	12.1536
10	0.3831	-0.1202	-0.2051	0.962	0.3662	0.6702	0.0037	0.0593	0.0105	0.023	0.175	-0.2278	0.3544	0.004	0.0001	0.4064	-0.0029	0.0164	0.1028	0.0418	0.1552	38.7848	54.9594	32.9101
11	4.6365	4.3721	1.1458	5.6341	0.3604	0.6414	1.108	-0.9546	-0.7427	1.2485	0.0805	-0.0583	-0.0457	0.2707	0.1261	0.1174	0.0194	-0.0084	0.2943	-0.0536	0.1427	2.3458	36.413	22.2499
12	0.2895	-0.4778	0.0074	0.8611	0.0732	0.1137	-1.0237	-0.421	0.1898	0.6297	0.4867	-0.072	-0.1634	0.6681	-0.0133	0.1105	0.0381	-0.0665	0.2458	0.0143	0.2186	2.3169	40.7088	45.465
13	0.8534	-0.1602	-0.5673	0.3603	0.5374	1.9079	0.4236	0.7622	1.0445	-0.2417	0.2241	-0.4541	-0.6911	-0.2532	0.0565	0.1806	0.0628	-0.0424	0.1862	0.0279	0.3399	25.0498	42.64	51.9919
14	0.8719	1.1423	0.0784	1.5742	0.2012	0.1693	-0.1634	-0.3356	-0.7816	-0.7538	0.1323	-0.7007	0.2004	-0.6601	0.0064	0.2539	-0.0554	-0.0061	0.2021	-0.0018	0.0808	38.9082	39.3858	33.1269
15	1.9876	2.1016	-2.3665	3.8635	-0.1557	0.5188	0.0271	-1.0151	1.5128	0.8189	0.1435	0.7654	-0.3781	0.3018	0.2007	0.1101	0.0635	0.0145	0.1624	-0.0227	0.0774	24.781	35.6258	14.6745
16	1.821	-2.6952	-1.4123	5.001	2.8217	1.7064	0.4379	1.4269	0.6068	-1.2925	-0.0107	0.0183	0.0791	0.1525	0.1579	0.1851	0.0376	-0.1174	0.2317	0.0179	0.1116	4.9729	63.2185	44.7087
17	0.038	-0.1295	-0.0728	0.5742	0.6354	1.0418	-0.2666	-0.2741	0.1321	0.002	-0.0966	0.007	1.0847	-0.0769	-0.0027	0.094	0.0037	0.0275	0.209	0.0602	0.1543	-0.2433	59.077	21.9194
18	0.1835	-0.0051	-0.1458	0.1402	-0.0889	0.1477	0.0762	-0.3882	-0.3997	0.1166	0.4972	-0.3263	-0.525	0.1042	0.0014	0.1026	-0.0115	-0.0314	0.1909	-0.0039	0.2013	20.1898	57.212	9.7678
19	2.404	-0.9078	0.9469	4.39	-0.9166	2.1802	0.4473	0.742	-0.8892	0.0854	0.5534	0.9163	1.2501	-0.4313	0.1092	0.2174	0.0071	-0.0476	0.2039	0.0093	0.0479	38.0263	60.3254	24.8478
20	6.4939	0.7146	-0.5442	0.1756	-0.1017	0.087	-0.4408	1.2914	-0.4928	0.3775	0.5785	0.5072	0.955	-0.4645	0.0261	0.1894	0.0049	0.0262	0.2017	0.0588	0.1786	28.4838	63.89	46.2299
21	4.5289	2.3884	-2.7797	5.9482	-5.1684	4.9117	-0.1671	0.4863	-0.3424	-0.3315	-1.1241	-0.493	-0.1646	0.7966	-0.4822	0.0532	-0.0319	-0.0847	0.2882	-0.0431	0.1138	-2.6563	27.1958	14.7231
22	0.8013	0.2147	-1.5546	0.5686	-1.8289	7.9483	0.4092	0.2985	-0.0968	-0.3432	-0.0516	0.5706	-0.5215	-0.627	0.4615	0.0452	0.0289	0.0341	0.1841	-0.0177	0.2268	-7.5966	33.2213	49.0199
23	0.5356	0.0599	-1.8601	0.26	-0.9864	8.7963	0.5462	0.2772	-0.4445	0.1057	0.1046	0.1027	-1.2238	0.7029	0.1458	0.0981	0.0365	-0.0405	0.2222	-0.0051	0.1454	24.1036	37.1735	63.7043
24	2.7193	3.1862	-1.4525	7.7126	-3.7314	2.8122	0.4014	0.0573	-0.4292	0.7134	-0.7648	-0.938	-0.2349	-0.1311	-0.1471	0.0667	0.008	-0.0869	0.2164	-0.0614	0.0397	48.5955	32.9455	38.7487
25	5.295	0.4249	2.8262	0.9012	-0.3083	1.8226	-0.4498	0.1526	0.7983	-0.0916	0.2643	0.027	-0.6773	0.2413	-0.2731	0.1553	-0.0207	0.0122	0.2214	-0.041	-0.0227	31.857	26.8243	8.4423
26	4.7093	-0.2968	1.8737	2.6951	-2.0351	2.5292	-0.2667	-1.3187	-0.3282	0.2079	-0.7652	-0.3953	-0.5965	-0.7576	-0.1876	0.225	-0.0474	0.1105	0.2799	-0.0158	0.135	2.007	72.4436	53.2258
27	1.2648	0.5287	0.0557	0.5246	-0.6629	1.5316	0.0971	-0.289	0.2051	-0.221	0.9521	0.6211	0.4179	-0.5597	0.421	-0.3709	-0.0816	-0.2647	0.2811	0.0254	0.1104	-10.736	66.6224	20.8768
28	0.1319	0.0082	-0.083	0.126	0.0784	0.0916	0.2952	0.6667	-0.1957	-0.4868	-0.5687	0.2002	0.1558	-0.1747	-0.002	0.1946	-0.0339	-0.0526	0.1763	0.0162	0.1245	16.4008	62.9159	-1.2125
29	0.2142	-0.3548	0.0704	0.6889	-0.2379	0.1346	0.2719	-0.2061	0.1407	-1.0085	-0.1526	-0.3851	0.086	0.1931	0.0085	0.1091	0.0465	0.0216	0.124	-0.0243	0.1336	46.1164	66.9009	17.3049
30	0.0118	0.0291	-0.0212	0.0558	-0.0523	0.0606	-0.137	-0.5546	0.3004	-0.2793	-0.236	-0.669	0.5005	0.4114	0.0001	0.2465	0.0325	-0.0653	0.2595	-0.0207	0.2	37.1984	72.3833	50.7425
31	0.8864	0.2906	-0.536	0.8566	0.3942	0.5662	-0.311	0.1155	-0.0709	0.3228	0.1431	-0.0212	0.5701	-0.3313	-0.0006	0.2378	-0.052	0.0344	0.152	-0.0151	0.2223	10.8456	5.9224	21.6411
32	0.5796	0.7104	-0.5131	0.8452	-0.5305	1.0771	0.2308	0.1177	0.2054	0.2464	-0.0399	-0.2275	-0.1497	-0.1594	0.0008	0.1791	-0.0408	-0.0326	0.1777	0.0765	0.3031	0.2431	9.2563	41.7696
33	0.3983	0.1577	0.6899	1.3481	0.2178	1.4054	0.0287	-0.3196	-0.2199	-0.5374	-0.4933	-0.0601	0.1434	-0.0922	-0.0512	0.3411	-0.0462	0.0536	0.1041	0.0774	0.2354	16.103	12.8357	58.0803
34	0.9696	-0.1133	-0.902	0.3423	-0.4095	1.8055	-0.5441	0.1373	0.3735	-0.832	0.1168	0.2673	0.8103	-0.0315	-0.0113	0.36	0.0282	-0.0038	0.1765	0.0189	0.1577	36.7506	11.5473	48.0736
35	0.6614	-0.3463	0.6277	0.8006	0.2297	1.0664	0.107	-0.0552	-0.4068	0.1446	-0.0579	0.2462	0.1433	-0.2469	-0.0003	0.1936	0.0304	-0.0057	0.1304	0.0409	0.1386	33.6453	7.3255	25.6862
36	1.0027	-0.5169	-0.3032	0.5915	0.3814	0.2804	-0.0001	0.1417	-0.0888	-0.1433	0.2213	0.3783	-0.3389	-0.0097	0	0.2863	-0.0316	-0.0842	0.114	-0.0328	0.2359	13.6731	93.6765	43.4327
37	0.5803	-0.4065	0.695	0.6031	-0.396	0.6571	0.1107	-0.1341	0.2867	-0.5305	-0.0951	0.1518	0.4713	0.144	0.0001	0.2171	-0.0041	0.0116	0.1141	0.0264	0.2036	-1.5655	90.495	26.3775
38	0.6947	-0.0271	-0.355	0.5566	-0.5666	0.7999	-0.0501	-0.2788	-0.0036	-0.3697	-0.1734	-0.3694	0.5027	0.1133	-0.0012	0.0304	-0.0159	-0.0235	0.2061	0.008	0.217	10.019	87.1094	6.6299
39	1.4098	0.7748	0.5621	0.8001	-0.2508	1.0376	-0.6094	-0.0984	0.3354	0.2688	0.3097	0.2153	-0.1709	-0.223	-0.0074	0.2559	0.0126	-0.0251	0.1401	-0.0164	0.1008	32.5571	88.3154	11.3397
40	0.5387	0.5039	-0.3734	0.695	0.1698	1.0417	0.0705	-0.12	0.1775	-0.0723	0.1651	0.2397	0.0236	-0.2389	-0.0006	0.2684	-0.0309	-0.013	0.1415	0.0153	0.1894	34.7819	92.3244	33.9934
41	2.0004	4.8342	1.1641	6.7699	5.2486	4.8923	-0.1372	-0.2856	-0.4724	-0.0799	0.0132	0.6538	-0.0414	0.0763	-0.0223	1.1372	-0.3324	-0.0396	0.4125	0.3244	0.5144	4.4371	-5.1878	29.5037
42	0.6138	0.3314	-0.1616	0.2368	0.0849	0.526	0.211	0.0224	-0.3427	-0.044	0.4266	0.2547	0.4162	-0.4738	-0.0033	0.4027	-0.1875	-0.0326	0.2984	0.2627	0.4552	4.1937	-0.8439	52.3139
43	1.2493	0.6149	-0.6214	1.9357	-2.9214	7.0808	-0.4778	0.2896	-0.0878	0.4311	0.018	0.036	0.1671	0.2183	-0.0137	0.8553	0.039	0.2381	0.2359	0.0486	0.4859	25.561	1.1397	59.5342
44	5.3054	-5.4161	-1.8594	6.2523	4.1064	7.4051	0.5272	0.3246	-0.6795	-0.5774	0.9005	-0.4648	0.7769	1.2624	-0.1043	1.1207	0.0158	0.6336	0.2522	0.1478	1.0506	26.1377	-5.6021	23.5538
45	2	-2.2558	-1.8983	4.1017	3.7362	4.4965	-0.1136	-0.4446	0.6742	0.0746	0.0751	0.3324	-0.0044	-0.0736	-0.0218	1.4357	0.3813	-0.0753	0.332	0.111	0.4522	5.4523	104.8213	37.2441
46	2.3043	-1.6231	-0.6188	1.1426	0.435	0.1669	0.3439	0.0372	0.5451	0.0507	0.1237	0.3116	0.0594	-0.4939	-0.0054	0.5172	0.0997	-0.0451	0.2781	0.0296	0.1793	-0.1773	100.5941	15.2614
47	3.9241	-1.7868	0.8018	0.8193	-0.5788	1.9994	-0.4124	-0.1516	-0.1366	-0.8563	-0.3847	0.0228	-0.2162	-0.1856	-0.1839	0.4901	-0.2034	-0.2017	0.1238	0.0952	0.3898	18.7901	98.8394	2.9523
48	3.7795	3.5712	1.2938	5.0634	1.1111	2.1693	0.2183	0.1135	0.3154	0.2756	0.0983	-0.2342	-0.688	0.4352	-0.0237	0.5515	-0.0446	-0.0759	0.2212	0.0708	1.2298	28.1018	105.2935	38.046
49	0.1834	-0.1859	-0.0007	0.1817	-0.0836	0.1394	0.0657	-0.4605	1.1408	1.1789	-0.375	0.1542	0.1353	0.2039	-0.0031	0.4003	-0.0491	0.0824	0.1614	0.0806	0.3833	6.5521	3.2306	30.6958
50	6.4583	-4.4518	3.9442	3.8235	-2.9448	4.2823	1.0706	1.3136	0.0775	-0.0039	-0.5928	-0.6636	0.0978	0.6484	-0.0186	0.2563	-0.0134	-0.0046	0.204	0.0275	0.4121	6.9781	6.7127	49.2817
51	1.0506	-0.2939	1.5587	0.5214	-0.3826	2.3175	-0.8377	0.3303	0.0107	-0.2655	0.0933	0.03	-0.8975	0.4337	-0.0457	0.2429	0.0675	0.0344	0.1878	-0.0636	0.3575	24.7504	8.3153	54.6315
52	0.8783	0.4215	0.6896	2.8405	3.1076	4.7313	0.0675	0.0423	0.3111	-1.184	-0.2306	-0.3803	0.1539	-0.662	-0.111	0.2632	0.0437	0.0631	0.0272	0.0522	0.1745	35.4197	5.8678	39.5186
53	2.872	1.9301	0.584	1.4511	0.5439	0.5288	0.4428	-0.6214	0.2824	0.516	-0.4589	0.6038	-0.1956	-0.1066	-0.0158	0.278	-0.0422	0.0591	0.1434	0.0567	0.2438	24.336	2.7548	24.8687
54	1.2906	-1.1494	-0.0799	1.09	-0.1118	0.6623	-0.0435	0.8853	-0.1617	-0.352	-0.4545	0.7679	-0.092	0.2143	-0.0117	0.3969	-0.0181	-0.0841	0.1981	0.0868	0.3393	7.3205	96.3924	35.6712
55	0.6388	-0.3874	0.2204	1.1317	-0.8374	0.6154	0.6222	-0.1497	0.2427	0.038	-0.7021	-0.1562	0.4458	0.7866	-0.0107	0.1512	-0.0203	0.0664	0.1875	0.0462	0.2587	3.2843	93.0679	17.5943
56	6.0061	5.2308	-0.6882	7.1543	1.1398	1.1932	-0.0882	-0.7429	0.1554	0.3184	-0.4711	0.1795	0.0506	-0.1	0.2125	0.0529	0.0578	0.0189	0.1568	-0.0398	0.317	19.2742	91.6635	7.9245
57	5.5073	2.724	-2.055	3.0021	-3.4039	4.1903	-0.2035	-1.0149	-0.7775	0.857	0.0464	-0.3542	-0.6258	0.1056	-0.4014	0.2634	0.085	-0.035	0.1301	-0.0489	0.198	33.2405	93.9639	20.0923
58	0.1187	-0.0214	0.0346	0.8242	-0.6774	0.5409	0.5043	0.0054	0.0911	-0.3912	-0.223	0.5868	1.0315	-0.5638	0.0138	0.2193	0.0896	-0.0816	0.2122	-0.0313	0.3253	25.9029	96.8642	37.0013
59	1.2206	-0.3541	0.2562	0.8529	0.5562	0.5695	0.2906	-0.053	0.0925	-0.1022	-0.131	-0.1585	-0.281	0.1892	-0.4369	0.0911	-0.0583	0.1045	0.1424	-0.0495	0.2623	11.1733	12.0085	20.6462
60	0.0818	0.2835	0.0144	1.0423	-0.2214	0.9384	0.5468	-0.4606	-0.4207	0.9417	-0.0517	0.2086	-0.7919	0.1071	0.007	0.4085	-0.1377	-0.0608	0.2574	0.0115	0.1995	0.3271	15.0478	40.1884
61	1.6976	-0.291	-0.4254	0.3465	0.3435	3.624	-0.1934	0.0476	-0.1743	0.234	0.1402	0.2501	-0.5473	0.3182	0.0194	-0.207	-0.0667	0.5053	0.2295	0.0638	-0.596	15.4307	18.7519	56.5884
62	3.1841	0.1245	-1.9837	8.2237	-3.3834	9.8046	-0.2857	-0.2811	0.2132	-0.303	-0.4392	-0.4462	0.8009	0.1992	-0.3264	0.1424	-0.0087	-0.04	0.093	-0.0129	0.1331	36.151	17.6075	47.227
63	2.6331	1.7479	0.1188	2.8489	-1.705	3.0095	-0.0955	0.2771	0.1554	-0.6492	-0.048	0.2304	0.4998	0.3109	-0.1344	0.1203	0.0972	0.0259	0.0924	0.0548	-0.0122	33.6381	13.4417	25.023
64	0.4314	0.2535	-0.1758	0.2544	-0.0769	0.0748	-0.3954	-0.3111	0.0837	0.2929	0.5071	0.1036	-0.4435	-0.5403	-0.0015	0.0682	-0.0301	-0.0338	0.2119	0.0744	0.1567	14.2961	87.6236	44.2279
65	0.0522	-0.0231	-0.0636	0.1044	0.0434	0.0797	0.4689	-0.2854	1.1576	-0.0532	-0.0061	-0.1482	-0.0795	0.2323	0.0023	0.2705	-0.0861	0.0949	0.2077	-0.0486	0.2274	-1.2027	84.5575	27.9146
66	1.3811	0.0182	0.6566	-0.0005	0.0227	0.7211	-0.0462	-0.3699	0.2933	-0.2496	0.1296	0.1493	0.1998	0.0597	0.2989	0.068	0.1873	-0.0635	0.4301	-0.0179	0.1621	9.7859	81.1958	8.2067
67	0.8482	1.3409	-0.213	3.3176	-1.3263	0.8667	-0.4592	0.0314	-0.3809	0.2978	-0.2734	-0.7004	-0.0994	0.2511	-0.03	0.1392	0.0483	-0.0163	0.1719	-0.0023	0.014	32.1785	82.3297	12.2851
68	0.7998	0.3418	0.0551	1.3918	0.0069	0.9906	0.1012	0.2185	0.5423	0.1239	-0.1638	-0.2474	-0.1929	0.377	-0.1295	0.1612	-0.0785	-0.0118	0.253	0.0559	0.075	34.8461	86.2564	34.4859
69	2.9605	0.6584	-0.773	1.4404	0.6999	0.7852	0.009	0.3163	0.551	-0.3258	-0.0184	0.153	-0.1162	-0.1461	-0.0001	0.128	0.0088	0.0119	0.1704	0.0306	0.1581	10.0602	34.8915	10.8987
70	0.8424	0.3615	-0.5293	1.3021	0.9229	2.0973	0.0368	0.1713	0.2537	-0.2882	-0.0074	0.6587	-0.5018	-0.4455	-0.0063	0.1248	0.0238	-0.0208	0.1008	0.0243	0.2475	-5.9074	38.7953	34.7078
71	2.7919	1.3934	1.0976	1.6222	-0.1726	1.0879	0.0421	-0.41	0.4242	0.5771	0.0946	0.3468	-0.8631	-0.2707	0.0184	0.1408	0.007	-0.0247	0.1255	-0.0278	0.1488	12.1233	43.4619	56.793
72	1.1877	-0.401	-1.0838	1.2025	0.0922	1.0559	-0.1664	-0.2842	0.7017	0.4248	0.4371	-0.7213	-0.0229	0.4772	0.0096	0.1865	-0.032	-0.0068	0.1396	0.0072	0.0745	39.2565	42.3183	46.4915
73	1.1891	-0.3214	1.2652	1.2443	-0.003	2.328	-0.6522	0.6106	0.7032	-0.5595	0.3683	-0.2661	-1.0375	1.1413	0.0031	0.0823	0.0062	0.082	0.0894	-0.0399	0.08	37.985	36.9108	18.2213
74	2.279	-0.7957	-0.0609	1.4446	0.9009	0.7346	-0.0109	-0.3623	-0.376	0.4281	0.0111	0.0943	0.3791	0.0453	0.0096	0.149	-0.0049	0.0061	0.1349	0.0572	0.0959	15.2324	64.5988	53.6513
75	0.5339	0.1189	0.9725	1.6833	0.7818	2.0645	0.0006	-0.186	-0.202	0.0358	0.107	0.3444	0.2658	-0.5057	0.002	0.0884	-0.0083	0.0347	0.1906	0.0476	0.212	-5.923	60.9316	34.3407
76	1.9891	-0.3081	-0.0325	1.9098	-1.6078	1.1618	-0.0272	0.1528	-0.5303	-0.4313	0.083	0.2009	0.4407	-0.379	0.0045	0.1591	-0.0469	-0.0325	0.1735	-0.0552	0.175	6.555	56.4686	8.4086
77	3.1949	0.3276	1.8166	1.692	-0.6969	2.018	-0.0472	0.7637	-2.6597	-0.5178	0.7765	-1.1105	0.4019	0.6701	-0.0082	0.1652	0.065	-0.0518	0.0316	0.1198	-0.3199	35.2681	57.6113	11.7001
78	0.3807	0.2824	-0.8122	1.6915	-0.3432	2.3217	0.0052	-0.0692	-0.3162	-0.2174	-0.0179	-0.401	0.9558	0.9106	0.0317	0.0617	-0.0055	-0.0293	0.1895	0.0132	0.1572	40.5598	62.5536	39.6848
79	-0.0579	0.1038	-0.1139	0.7424	-0.6076	0.6385	0.1807	0.0364	0.2009	0.1807	-0.0956	0.1003	-0.2792	0.0855	0	0.1037	-0.0335	0.012	0.1772	0.0033	0.1494	7.7368	18.153	26.7119
80	0.1873	-0.1969	0.6069	0.282	-0.5849	1.061	-0.0469	-0.0219	-0.0169	-0.1548	0.0914	-0.1832	0.1297	0.1713	-0.0001	0.1797	-0.0523	-0.0001	0.1566	0.0044	0.2637	5.7078	21.4275	44.5299
81	0.6712	-0.5364	-0.3491	0.1577	0.2908	0.099	-0.0509	0.3328	0.0621	-0.1255	-0.2107	0.073	-0.0521	0.1454	-0.002	0.1346	0.0022	0.0041	0.19	0.0417	0.166	22.257	23.3537	51.9468
82	-0.0371	-0.0681	-0.0412	0.9299	0.0589	0.5711	-0.0367	0.2738	0.0455	0.0404	-0.0388	0.2058	-0.1777	-0.3239	-0	0.189	-0.0114	0.0035	0.1302	-0.0193	0.1626	34.6563	21.1833	38.7256
83	0.4583	0.4596	0.1854	0.7887	-0.456	0.3922	0.0346	-0.052	0.0803	0.1117	0.0226	0.1094	-0.1681	-0.2036	-0	0.0934	-0.0165	0.0333	0.1173	-0.0108	0.1092	25.6481	18.0422	23.1421
84	0.4841	0.1789	0.3621	0.5013	-0.0403	0.2245	-0.0666	0.2167	-0.1709	0.2179	0.0019	0.0835	-0.2437	0.1586	0.0001	0.1466	0.0185	-0.0124	0.1633	-0.0139	0.1854	9.3413	81.4875	39.099
85	0.134	-0.0814	-0.2645	0.0867	-0.0795	0.487	0.109	0.0337	-0.2499	0.0154	-0.0584	-0.1742	0.1348	0.0375	0.0021	0.1632	-0.0248	-0.0078	0.1658	0.0332	0.1628	3.17	78.3456	22.2848
86	0.7212	0.5732	0.0782	0.2799	0.0149	-0.0901	0.0314	-0.3031	-0.0957	0.1391	-0.1425	0.0517	0.0884	0.0498	-0.0005	0.1079	-0.0005	-0.0254	0.1063	-0.0197	0.0983	17.4974	76.5619	10.9683
87	-0.0025	0.0902	-0.2094	1.5557	0.6057	0.3805	-0.0329	-0.3664	0.0355	0.3582	0.0336	0.2257	-0.0517	-0.3179	0.0266	0.1428	-0.0119	0.0166	0.1493	-0.0475	0.1044	32.6603	78.6151	20.8508
88	0.8465	-0.3513	-0.8475	1.015	0.8238	0.8065	-0.0133	-0.0083	-0.025	-0.5686	-0.2843	0.3082	-0.2272	-0.2266	-0.0517	0.1434	-0.0223	-0.052	0.1171	0.0032	0.1133	27.6242	81.5449	38.2246
89	2.3609	-1.6726	2.7663	1.4695	-1.7283	3.9505	-0.1087	-0.6713	-0.1758	-0.1944	0.348	-0.069	0.6485	-0.9341	0.0265	0.1286	-0.0639	0.0007	0.1054	0.0095	0.2154	11.4415	31.7322	9.8688
90	0.2294	0.2466	-0.0147	0.2745	-0.0875	0.1946	-0.0619	-0.4978	-0.3952	-0.1495	0.1334	0.3737	-0.2291	-0.1223	0.0007	0.159	0.0191	0.0048	0.1934	0.0588	0.1782	-6.96	35.5157	33.5417
91	0.1279	0.1024	-0.2191	2.4369	1.4534	1.4988	-0.2165	-0.1736	0.0197	0.5278	0.5974	-0.3107	0.1484	0.5494	0.0437	0.1733	0.0957	-0.0192	0.128	0.009	0.0611	10.1764	40.5976	57.9707
92	0.3994	-0.1536	0.2164	0.3786	-0.3607	0.3471	-0.3895	0.4548	0.1166	0.0164	0.6194	-0.0822	0.329	0.4579	0.001	0.1802	0.0687	-0.0521	0.2034	-0.0423	0.1829	39.2766	39.8101	49.1633
93	0.5772	0.0287	0.315	3.5606	-0.5102	0.9383	-0.2673	0.3885	-0.144	0.5395	-0.1029	-1.0871	-0.0274	0.0675	-0.0202	-0.0103	-0.0402	0.0747	0.1444	-0.0154	0.1102	40.0442	34.1541	19.4668
94	0.6208	-0.313	0.2114	0.2053	-0.0084	0.142	-0.2083	0.0014	-0.3432	0.2772	0.1475	-0.0242	-0.3251	-0.6331	0.0003	0.1933	0.032	0.0328	0.1813	0.0012	0.1583	16.8169	67.751	54.4157
95	0.5899	0.5406	0.0683	1.3433	-0.0949	0.3518	0.1539	0.4867	-0.242	0.3634	0.3413	0.353	0.0778	-0.0364	0.0795	0.0108	-0.0138	0.0172	0.189	0.0564	0.2329	-6.7098	64.212	35.7241
96	1.8451	-1.73	0.5269	4.0597	0.2735	0.5754	0.3699	0.8147	-0.4292	-1.0733	0.1354	0.0571	-0.3596	0.5358	0.0097	0.1213	-0.1006	0.0196	-0.0165	0.0887	0.1072	4.4029	59.3735	7.865
97	1.7931	-0.9744	1.3508	0.6429	-0.9587	2.5673	-0.2455	-0.1189	-0.1748	0.0746	0.1603	-0.1324	-0.2995	0.4748	-0.2826	0.08	-0.009	0.0747	0.0744	-0.0061	0.1675	34.6392	60.2048	9.2009
98	0.2239	-0.3661	-0.1978	2.1696	-0.982	1.2664	-0.0786	-0.1514	0.3738	-0.2759	-0.0823	-0.9907	-0.1259	0.3841	-0.0723	0.2499	0.0353	-0.0224	0.1569	-0.0237	0.09	42.318	65.2714	38.0425
99	0.8515	-0.2623	0.3551	0.5223	-0.5446	5.2172	-0.2595	0.6199	-1.0057	0.3326	-0.2329	-0.1284	1.46	0.0125	-0.0148	0.286	-0.0535	0.0954	0.1137	0.001	0.1664	9.5275	26.4384	14.5895
100	6.7506	-1.9675	-1.1959	1.2903	0.6559	2.0413	-0.1813	-0.1897	-1.2471	0.9196	-0.4198	-0.3591	0.6562	-1.0467	-0.1052	0.1708	-0.017	-0.0778	0.1476	0.046	0.1921	-4.0291	30.2319	37.6955
101	0.7847	-0.7229	-0.7378	5.5882	-1.6354	2.0009	0.6026	-0.6758	0.3667	-1.1223	0.3539	-0.4091	1.0276	-0.7437	0.1282	0.207	-0.0247	-0.0173	0.2404	0.0041	0.1487	14.075	34.4346	57.3637
102	0.0762	0.2167	-0.0925	0.5493	-0.3163	0.1726	-0.0529	0.03	-0.6797	-0.3633	0.2104	-0.3439	-0.1644	-0.0794	0.0487	-0.7817	-0.6469	0.4105	-0.3549	0.2749	0.0952	39.0635	33.0855	46.3772
103	1.9857	6.4349	-4.2126	4.3467	-4.2351	8.0834	-0.5362	0.1718	-1.1593	0.3777	0.3411	-0.6986	0.8327	1.199	-0.1007	0.1836	0.019	0.0187	0.0693	-0.0011	0.0768	36.1579	28.0029	19.7954
104	0.1211	-0.1051	-0.4444	0.4269	1.1452	3.3895	0.4335	-0.33	0.6961	-0.3224	-0.1267	0.2813	-0.6161	-0.1862	-0.014	0.0565	-0.0083	0.0246	0.1877	-0.0679	0.2025	13.8867	73.135	50.4649
105	3.8738	-0.4879	-4.5477	0.8791	-1.5584	2.0026	-0.0814	0.059	1.286	0.4206	0.4678	-0.8177	-0.8917	-1.0374	0.3299	-0.0563	0.0364	-0.0991	0.2038	0.0593	0.2062	-4.7524	69.5104	31.1701
106	8.0249	2.0048	-1.64	1.6616	0.1928	5.4125	-0.7036	1.3114	0.0339	0.0748	0.8238	0.8139	-0.7532	-0.4684	0.0695	0.0643	-0.0433	-0.0072	0.0448	0.058	0.072	8.298	65.4359	7.5421
107	3.8677	1.1245	-5.8714	0.796	-1.3927	2.0045	0.7206	0.0496	0.1264	0.1745	0.2565	0.362	-0.6879	-0.3546	0.3675	0.2172	-0.0583	-0.0178	0.0842	-0.0665	-0.0199	34.9779	66.8549	12.3333
108	5.8804	-2.8875	0.3058	1.6185	-0.6384	1.1642	0.4114	0.0071	1.2037	-0.636	-0.5057	0.0457	-0.9289	0.9566	0.0253	0.2456	-0.0111	-0.0597	0.1219	0.0191	0.0724	38.486	71.4351	38.6844
109	3.2751	-0.4537	2.3513	5.8082	-3.6747	6.2166	-0.1251	-0.2351	0.5112	-0.3236	-0.6872	0	0.703	0.0715	-0.5682	0.1667	-0.0271	0.0852	0.0787	-0.0606	0.0594	12.5977	14.7315	23.6818
110	0.1652	0.1174	0.0855	0.0695	0.0547	0.088	0.1891	-0.1086	-0.4211	-0.2243	-0.0725	0.4801	-0.161	0.3481	0.0003	0.3737	0.0578	0.0159	0.2502	0.0385	0.1563	4.0639	17.3682	39.5001
111	0.5974	-1.0056	-0.4292	2.575	0.6047	0.3286	-0.1139	-0.0441	-0.8242	0.1051	-0.4043	1.1337	0.4082	-0.063	-0.0087	0.2046	0.0413	-0.077	0.1121	-0.0469	0.1664	16.2399	20.2314	52.5347
112	0.3838	1.077	0.4425	4.6826	1.5852	0.6342	0.562	0.1799	0.1006	1.0613	-0.7783	0.1013	0.3371	-0.2263	-0.0323	0.2685	-0.0331	-0.0429	0.0847	-0.0006	0.1315	32.882	19.2799	44.9815
113	0.2266	0.0574	0.2979	0.3338	0.449	0.7021	0.3778	-0.2876	0.0714	0.338	-0.4559	0.0098	0.4555	-0.4985	-0.0003	0.1745	-0.0373	-0.0379	0.1392	-0.0097	0.0677	30.7053	15.882	27.0592
114	0.1082	-0.0339	0.1736	0.4111	-0.1378	0.2646	-0.2741	-0.1035	0.1599	0.5317	-0.4635	-0.0731	-0.3987	-0.1054	-0.001	0.1938	-0.0074	-0.065	0.1699	-0.0287	0.1658	14.9431	84.9077	40.9606
115	0.1097	-0.119	0.0365	0.1419	-0.1061	0.1433	0.377	-0.0493	-0.2847	0.3417	-0.654	-0.2302	-0.5687	0.5901	0.0043	0.1607	-0.0644	0.0258	0.1472	0.0375	0.0872	2.5573	82.3048	27.7057
116	0.9051	-0.3283	0.5233	1.5318	-1	0.7782	0.0234	0.0241	0.181	-0.2777	0.1181	0.5151	-0.0277	0.3901	0.6761	0.0765	-0.0563	-0.0521	0.141	-0.0534	0.1493	11.5654	79.6361	11.8272
117	2.2029	4.0813	2.0875	8.7545	3.6562	2.0983	-0.163	0.0801	0.2313	-0.298	-0.1768	0.8192	0.1447	0.4367	-0.7349	0.0714	-0.0133	0.0711	0.0863	0.0356	0.0293	29.5173	80.5674	15.1841
118	0.5017	-0.3234	-0.2284	0.7298	-0.0459	0.185	0.4436	-0.1108	0.2791	-0.678	-0.2651	-0.2439	0.2981	-0.0293	-0.0079	0.2489	-0.0082	0.0491	0.12	0.0013	0.0369	31.5511	83.7361	33.1988
119	0.7536	-0.4237	-0.4549	3.3554	3.1047	2.9143	-0.806	-0.3118	-0.4247	0.5627	0.0941	0.9197	0.8142	-0.3575	-0.012	0.1726	-0.047	0.0984	0.2913	-0.0958	0.3291	2.3705	1.4017	26.598
120	0.0869	0.0588	-0.0898	0.127	0.0189	0.0242	-0.2538	0.1124	-0.0655	0.5283	0.2346	0.3467	-0.2341	-0.4898	0.0003	0.2033	-0.0447	-0.0397	0.2945	-0.0532	0.2863	1.5569	6.0397	52.0477
121	0.5999	1.0416	-0.6377	1.8093	-1.0709	0.7075	-0.0825	-0.5018	-0.3852	-0.2873	-0.5746	-0.9287	-0.0285	0.6793	-0.0274	0.2033	-0.0271	0.0789	0.3378	0.0605	0.2299	25.6134	8.4415	60.7487
122	4.9443	5.8976	-3.8743	7.0585	-4.6663	3.0918	-0.3797	0.7985	-0.73	-0.9546	-0.6318	-0.8993	1.0768	0.5059	-0.5934	0.3698	0.0499	0.0069	0.3112	0.0736	-0.0685	41.4644	5.0152	40.8723
123	0.9464	-1.1553	-0.0344	1.4096	0.0597	0.0183	0.4179	0.3939	-0.3626	-0.4254	-0.6023	0.4669	0.2589	-0.1041	0.0031	0.1772	0.0166	-0.0045	0.1945	0.0112	0.0716	27.2154	0.8517	19.8232
124	0.3168	-0.0558	0.0101	0.1452	-0.0462	0.2059	-0.4295	0.0262	1.221	0.6725	-0.1827	0.4577	0.4787	-0.2764	0.0014	0.2821	0.0455	-0.0613	0.2778	-0.1178	0.4695	4.256	98.2153	40.6028
125	1.0321	-0.9979	0.4536	2.0068	4.0667	2.4585	-0.3573	0.6487	0.1646	-1.763	-0.4497	1.0579	-0.632	-0.4513	-0.0206	0.0307	-0.0296	0.0186	0.2765	-0.0657	0.3565	-2.5692	93.7637	16.1412
126	0.1049	0.1321	0.1644	0.1369	0.1552	0.1923	0.4669	0.0574	0.2343	0.1626	-0.2583	-0.4625	-0.0329	0.2305	0.0004	0.1731	-0.0193	0.0129	0.2321	-0.0073	0.244	18.652	91.5714	1.7899
127	4.2833	-4.576	2.5103	7.1837	-4.284	2.5492	-0.6021	-0.2423	1.5964	0.8288	-0.2692	-2.013	-1.1101	0.157	-0.1527	0.3139	0.0159	-0.1134	0.2189	0.0772	0.1696	38.8139	94.8024	17.3514
128	0.3541	0.2229	0.0891	0.488	-0.283	0.4236	0.6828	-0.4738	0.1299	1.089	-0.7867	-0.068	-1.0556	-0.6312	0.0068	0.4209	-0.0165	0.0017	0.2224	-0.0221	0.1767	29.9696	98.7475	41.2443
129	0.9772	-1.3248	1.7504	2.1112	-2.801	3.7027	-0.1675	-0.4432	0.1471	0.7594	0.2295	-0.7891	-0.8172	1.0215	-0.0577	0.2883	-0.0929	0.1176	0.23	-0.0797	0.4677	0.9974	0.4536	21.245
130	0.1219	-0.153	-0.0101	0.1852	0.0254	0.0716	0.5681	-0.3539	0.6678	0.5667	0.2048	-0.3584	-0.6293	0.6265	-0	0.1447	-0.088	0.0698	0.5059	0.1053	0.3187	-4.0568	5.7174	51.7056
131	3.0591	-4.2299	-2.89	6.2762	4.7337	3.9961	0.4154	0.4312	0.3045	-0.6516	0.2817	-1.0643	-0.1897	-0.405	0.1168	0.1203	-0.0435	-0.0448	0.3081	0.0437	0.1845	23.4963	9.4266	65.8269
132	1.2387	-0.1516	0.3053	2.7804	0.0524	0.7839	-0.8741	0.6269	-0.15	-0.1742	0.0273	0.6186	-0.5585	-1.3243	-0.0272	0.3896	0.0603	-0.0424	0.3229	0.0561	0.1004	45.7654	5.8095	44.3917
133	0.4656	0.829	0.29	1.4723	0.4223	0.6854	-0.1598	-0.8136	0.5823	0.0628	0.073	0.4294	-0.9167	-0.3139	-0.0044	0.1636	0.0303	0.0035	0.2901	-0.0218	0.1254	31.9959	0.4583	16.8823
134	0.2871	0.8993	-1.3876	2.9425	-4.5476	7.0061	-0.1242	0.2409	0.2931	-1.2241	-0.3024	-0.6016	0.7235	0.2874	0.0309	0.2452	0.2047	0.0349	0.362	-0.1227	0.5673	4.1646	99.0683	46.2515
135	0.1132	0.0644	-0.0536	0.1556	0.2126	0.5039	0.2333	-0.1463	-0.0079	0.4416	-0.1292	0.2498	0.3722	0.2844	0.0028	0.0734	0.0952	-0.0027	0.3601	-0.1922	0.419	-7.971	94.0849	17.7977
136	0.0192	0.0544	0.0374	0.1109	0.0523	0.0218	-0.3647	-0.7729	-0.1187	0.5111	-0.0686	-0.5625	0.697	-0.2375	0	0.2482	0.0751	0.0559	0.3803	0.0895	0.16	15.3715	90.6524	-2.6732
137	0.937	-0.267	0.251	0.1917	0.0289	0.1447	0.0912	-1.01	-0.2777	-0.4603	0.4539	0.1375	-0.1103	0.5739	0.0137	0.1912	-0.0041	0.0368	0.3093	-0.047	0.0624	42.0833	93.9817	12.9181
138	0.5577	-0.8287	0.1824	1.3217	-0.1418	0.2656	-0.9794	0.0573	-0.5468	0.1805	0.7023	0.0526	0.3702	-0.606	0.0178	0.4268	-0.0716	-0.0408	0.264	-0.0873	0.1482	35.2916	99.1418	42.9766
139	0.1222	-0.0392	-0.0631	0.0141	0.0216	0.0328	-0.1967	0.5851	0.3444	-0.7097	-0.2779	-0.0332	0.3164	0.0559	-0.0025	0.2175	0.0024	-0.0357	0.1771	0.0211	0.201	-2.4764	23.8576	26.1957
140	0.1327	-0.1134	0.1038	0.0993	-0.0357	0.0432	0.1216	0.4661	0.1681	-0.5065	-0.2434	0.0779	-0.0086	-0.0559	0.0006	0.1471	0.0443	0.0391	0.2227	0.0132	0.1797	2.7333	28.8587	53.1044
141	0.3111	0.5143	-0.131	1.0977	-0.5556	0.6816	0.1843	-0.3477	0.357	0.251	-0.3	0.6681	-0.4834	0.1377	-0.0052	0.0629	0.053	-0.0516	0.147	-0.045	0.1786	30.6282	30.4126	56.3068
142	0.0049	0.0781	-0.0009	0.2568	0.1504	0.1582	-0.1452	-0.0878	0.2218	0.3859	-0.2892	0.1003	-0.2313	0.1031	-0.0013	0.1764	-0.026	-0.0313	0.0604	-0.0177	0.1752	42.4445	25.9056	31.3085
143	3.7216	-4.118	0.6173	4.9683	-0.557	0.2685	-0.5358	0.2253	0.5997	0.5926	0.2095	-0.8043	0.0097	0.1505	-0.1052	0.0323	-0.0465	0.0823	0.0793	0.0018	0.0168	21.7996	22.0093	12.7807
144	0.1446	0.4126	0.0095	1.2772	0.2189	0.2715	0.3051	-0.1901	-0.2143	0.9743	-0.3471	-0.1096	0.3348	0.1078	-0.0043	0.246	0.0239	-0.0135	0.2352	0.0347	0.1233	-0.5904	75.856	41.9996
145	1.0101	0.2642	-0.7108	0.0923	-0.1243	0.464	-0.1003	-0.075	0.0212	0.275	0.299	0.4583	0.28	-0.6428	0.3645	0.0723	-0.0932	0.0143	0.1489	0.0072	0.1882	-1.6656	70.9377	14.4761
146	0.3146	-0.2637	0.0592	0.8125	1.0498	1.9722	0.1495	0.4856	0.0961	-0.0996	-0.2778	0.0188	0.4566	-0.77	0.01	0.0657	-0.0896	0.0217	0.154	-0.0167	0.1116	24.5057	69.5616	4.6179
147	0.0279	-0.0758	0.0774	0.4027	-0.1338	0.119	0.2203	0.1365	-0.0137	-0.6203	-0.4405	0.0908	0.1987	0.2909	-0.0041	0.1271	0.0291	0.0014	0.1415	-0.0745	0.0975	41.944	73.8036	26.1041
148	0.019	0.0261	-0.0045	0.0789	0.0962	0.0681	0.0404	-0.2947	-0.569	0.0425	-0.1847	-0.3067	0.0268	0.4128	-0.0003	0.1826	0.0189	-0.0137	0.1456	0.0004	0.0938	26.4521	77.4731	49.1667
149	0.2583	-0.1392	-0.1067	0.5276	0.0613	0.7256	-0.3517	0.1729	-0.4313	0.4071	-0.5726	0.2806	-0.2381	-0.8049	-0.0148	0.0998	0.0632	-0.022	0.378	0.0232	0.2962	-7.8229	27.7908	19.5599
150	0.1958	-0.0386	-0.129	3.5337	0.0053	0.0605	-0.1221	-0.4009	0.2188	1.3524	0.4493	-0.0519	-0.2962	0.5391	0.0368	0.1468	-0.0361	0.0872	0.2566	-0.0688	0.2039	-4.5229	34.3263	55.2994
151	1.1753	-0.2499	-0.1478	0.0547	0.0906	0.4538	0.6052	-0.3369	0.3154	0.4704	-0.0981	0.0195	-0.2323	0.3404	0.0242	0.1982	0.0238	-0.0029	0.2314	-0.0525	0.1139	31.1387	37.1738	62.8455
152	0.595	-1.3377	1.323	5.8011	-5.2149	4.7276	-0.4618	1.2748	-0.0582	-0.4584	-0.6032	-1.6233	0.3787	0.313	-0.2009	0.0297	-0.0974	0.0013	0.1985	-0.0544	0.1719	49.9122	31.5177	31.954
153	7.1644	-3.2346	-1.1719	4.4918	-0.0326	1.2551	1.1372	0.8748	0.977	-0.9407	-0.2158	-0.6044	0.3706	-0.6643	0.173	0.1013	0.0013	-0.0438	0.1907	-0.063	0.1344	25.6748	25.9503	5.1407
154	0.2622	-0.1927	-0.1249	0.2442	-0.0916	0.3201	-0.1673	0.273	0.3072	0.0641	-0.0056	0.6557	-0.0206	-0.758	-0.0006	0.0971	0.0191	0.0382	0.4399	0.0094	0.2668	-4.1804	71.8709	49.6597
155	1.6109	0.2659	-0.4907	0.1817	-0.4247	0.9438	-0.6428	0.9297	-0.8212	-0.8073	0.1167	0.5144	-0.7613	-0.2585	-0.0516	0.1824	-0.0189	-0.1119	0.2419	-0.0415	0.2918	-9.3043	65.4473	14.0667
156	0.1582	0.1433	-0.1288	0.4386	0.3939	0.7615	0.4375	0.1024	0.4994	0.2216	-0.4294	-0.2268	0.3532	0.3346	0.0049	0.144	0.0137	0.0602	0.2035	-0.0228	0.1374	23.4047	62.9867	-2.1222
157	5.5979	-4.0553	-4.5514	6.9107	3.937	6.8482	-1.328	-0.5507	-0.6867	0.8223	-0.0543	-0.4642	0.583	0.1468	-0.7962	0.0455	-0.052	-0.0334	0.208	0.0582	0.1802	49.013	68.1015	23.6777
158	1.331	0.4679	-0.3083	0.994	0.1958	0.7701	0.511	-1.038	-0.1573	0.5935	-0.0333	0.1641	0.1294	0.2296	0.0349	0.1069	-0.0223	0.0391	0.2889	0.055	0.1029	31.9949	73.1955	55.4254
159	0.6775	-0.6349	0.3902	0.7749	-0.8893	1.1757	-0.0343	0.5555	-0.6609	-0.2379	-0.6999	0.0917	0.4889	0.7785	-0.027	0.2225	-0.0074	-0.0805	0.2327	-0.0256	0.2365	16.9559	3.8365	14.0447
160	0.2195	0.1377	0.0895	0.1493	0.0528	0.0109	-0.2519	0.6188	-0.5341	0.1734	-0.176	0.5447	0.1657	-0.5556	-0.0029	0.2593	-0.0292	-0.0291	0.3299	0.0014	0.2779	-5.461	6.6761	33.884
161	0.0918	0.1267	-0.0421	1.5548	1.5034	1.8082	0.3269	-0.0588	-0.5333	0.1854	-0.9459	-0.0072	-0.691	-1.4513	-0.0532	0.2969	0.0421	0.056	0.3199	0.0466	0.2107	6.5993	12.3594	61.1064
162	1.4634	0.3306	-0.3444	0.4115	-0.4091	0.3895	-0.2623	-1.4078	0.0884	0.3012	-0.485	0.2408	-0.1416	0.727	-0.0061	0.1612	-0.0113	0.0242	0.3361	0.1179	0.2801	36.6545	12.5217	58.0168
163	0.1926	-0.1929	-0.1961	0.347	0.0751	0.2286	0.1697	-0.7622	0.1868	-0.5281	-0.219	0.0685	0.0091	1.0801	0.002	0.1775	-0.0296	0.0343	0.2914	0.0278	0.1484	43.1675	7.4201	29.0699
164	0.297	0.1398	0.2615	0.0171	0.0643	0.1668	0.7422	-0.414	0.2399	1.16	-0.4629	0.325	-0.5973	0.8317	0.0004	0.442	-0.0528	0.0557	0.1912	0.013	0.2332	21.4672	95.6569	49.4078
165	0.4055	0.0233	-0.2001	0.1571	-0.0717	0.132	0.2925	-1.2749	0.4828	0.6598	0.1128	0.2435	0.036	0.2187	-0.0016	0.2069	0.014	0.0415	0.2404	0.0168	0.2561	-5.2127	92.8594	35.3197
166	0.0808	-0.1054	-0.1142	0.1551	-0.0073	0.4542	0.4899	0.2613	0.1546	-0.322	-0.887	0.1046	-0.0288	-1.2183	-0.0019	0.2637	0.0567	-0.0862	0.3844	0.0043	0.2805	0.0551	87.6767	6.0076
167	2.4122	-3.5698	0.6984	5.501	-1.7351	1.4712	0.3542	1.164	0.13	-0.7999	-1.1226	-0.2083	0.3078	-0.3757	-0.051	0.0803	-0.0015	0.0452	0.2161	-0.0404	0.0794	30.0308	87.4045	1.7635
168	0.8981	-0.872	1.2169	1.976	-2.6071	3.5331	0.4622	0.7584	-0.4488	-0.6172	-0.8559	-0.2017	-0.2231	1.4589	-0.1368	0.3052	0.0428	-0.0759	0.2256	-0.0321	0.1637	43.2089	92.2713	28.4253
169	0.1276	-0.0931	-0.1364	0.1312	0.0877	0.1426	-0.4068	0.175	-1.642	-0.5035	0.3202	0.5393	0.1271	-0.3123	-0.0009	0.1772	-0.0395	0.0424	0.2681	-0.1063	0.4228	5.8064	1.221	14.8247
170	0.1964	-0.2753	-0.023	0.8926	0.4885	0.6303	0.0629	0.2691	0.0742	-0.1316	0.3752	1.0407	0.0934	-0.7977	0.0051	0.4318	-0.107	0.0328	0.1907	0.0623	0.2126	-8.4499	6.1098	44.9131
171	1.4721	1.4302	0.3556	2.2184	0.5309	0.1333	0.1314	-0.3054	0.1847	0.663	0.266	0.1764	-0.554	-0.8548	-0.0094	0.3409	0.0762	0.0133	0.1806	0.0559	0.2602	15.9289	11.3673	67.7175
172	0.5942	0.2869	0.073	1.3615	-0.1409	0.2165	-0.4754	-0.6156	0.0134	1.0909	0.5193	-1.0261	0.001	0.1497	0.0109	0.1898	0.011	-0.0357	0.2913	0.0139	0.2196	45.4542	8.9864	51.7311
173	0.3251	0.0925	0.0031	0.2282	-0.1555	0.0889	-0.2792	-0.077	-0.0006	-0.1157	0.226	-0.5988	0.4147	0.0835	-0.0021	0.1544	-0.0412	0.0155	0.2302	-0.0189	0.1379	39.3211	2.9551	19.1505
174	0.179	0.0588	0.2243	0.0655	-0.057	0.3371	-0.2662	-0.36	0.1836	1.1482	0.2422	-0.2833	-0.1987	0.0847	-0.0008	0.5143	0.0364	0.0163	0.2208	-0.0936	0.3108	10.4449	98.3292	51.2763
175	0.1258	-0.0046	0.0687	0.243	-0.1206	0.4762	0.3625	0.1204	-0.2339	-0.7106	-0.2345	0.887	0.7015	-0.3338	0.0003	0.2063	0.0719	-0.0845	0.3497	-0.0616	0.3696	-10.7573	93.5768	25.3344
176	0.3345	-0.4514	-0.4192	4.3295	-0.6737	0.7979	0.0509	0.4827	-0.1117	-0.7767	0.1573	0.569	0.1262	-0.7255	0.0219	0.1612	0.0005	-0.0581	0.3676	-0.0014	0.3073	7.5387	88.7919	-2.6615
177	0.0171	-0.0348	0.1111	0.4357	0.3635	0.5179	-0.5576	0.2734	0.2649	-0.1946	0.7458	-0.7003	-0.1043	0.6655	0.0086	0.2339	-0.0531	0.0779	0.2187	-0.0311	0.1848	40.1448	90.8626	5.8714
178	0.6009	1.8229	-1.1549	5.6204	-3.3562	3.5538	0.2984	-0.0183	-0.8514	1.1207	-0.1891	-1.0418	-0.4822	0.87	-0.1684	0.2146	-0.0315	0.0676	0.159	-0.0379	0.1193	41.8594	96.7271	39.0259
179	0.6099	-0.4487	-0.8914	0.7534	0.1875	1.5689	-0.3596	-0.3169	-0.7733	0.2316	0.2616	-0.0127	1.1464	-0.5667	-0.0389	0.1518	-0.0246	-0.0306	0.3603	0.06	0.2699	-7.6912	20.4579	21.8636
180	0.7066	-0.5159	0.8297	0.8524	-0.5597	1.365	-0.1049	-0.6802	-0.5992	-0.2643	-0.345	0.6701	1.0662	-0.4912	0.0504	0.1879	0.0683	0.058	0.5091	-0.001	0.0964	-3.3569	26.971	57.0449
181	1.556	1.0075	-0.2017	0.9514	-0.288	1.0722	-0.0729	-0.3365	-0.6251	-0.0498	-0.2115	-0.3915	0.398	0.2863	-0.1521	0.0332	0.0633	-0.0027	0.2793	0.0592	0.1413	32.0705	29.6185	63.6075
182	0.0754	-0.3274	-0.1933	1.2734	1.1035	3.9179	-0.2568	-0.0393	-0.7337	0.6721	0.0395	0.111	0.7066	1.152	-0.0623	-0.0935	-0.0991	-0.0561	0.2803	0.011	0.275	49.5905	23.9093	32.596
183	0.1003	0.0414	-0.0419	0.1458	-0.1799	0.1172	0.0932	0.3894	-0.0095	0.4588	-0.5456	-0.3407	0.3254	0.391	-0.0031	0.2817	0.0354	0.0094	0.1712	-0.0154	0.1235	24.706	18.5054	6.8041
184	2.989	-2.8253	1.1741	2.6905	-1.0989	0.4549	-0.021	0.3964	1.7629	0.6578	-0.5406	-0.9152	-0.6261	-0.1443	-0.3819	0.0217	0.227	0.3389	0.4691	0.1365	0.0442	-4.6031	79.1862	47.473
185	-0.0092	-0.0114	0.0009	0.0001	0.0354	0.0948	-0.1302	0.3644	0.858	-0.2371	0.1557	-0.2581	-0.9735	-0.2175	-0.0024	0.2888	0.0061	0.0024	0.2527	-0.0905	0.2389	-8.4879	72.8173	12.142
186	0.7828	0.2652	-0.2803	0.0913	-0.1071	0.0967	0.1691	0.6284	0.6561	-0.1496	0.5386	0.6856	0.0151	-0.5143	0.0052	0.156	0.0123	-0.0063	0.2581	-0.0263	0.113	24.0573	70.5975	-2.912
187	0.0164	-0.0477	-0.0081	0.2045	-0.1985	0.3035	0.2938	0.3317	0.408	0.5261	-0.3204	1.0096	-0.4718	0.7168	0.0005	0.1787	-0.0292	0.0518	0.2492	0.0108	0.2567	48.5786	75.7276	23.3355
188	0.8054	0.1651	-0.8199	0.097	-0.0778	1.61	-0.0094	-0.4674	0.3831	-0.4284	-0.2652	0.3083	-1.4032	0.1599	0.0113	0.2262	-0.0019	-0.0189	0.2417	-0.0001	0.0989	30.8929	80.759	54.2415
189	0.0949	-0.039	-0.1547	0.0755	0.0962	0.7228	0.1307	0.5682	-0.5595	0.5102	-0.3558	-0.3167	0.6301	-0.3642	-0.001	0.3074	-0.084	0.0287	0.2883	-0.085	0.301	4.6472	0.4202	18.4975
190	0.4549	-0.2244	0.6585	0.1737	-0.6335	2.3178	0.2661	0.0968	-0.1274	-0.2246	0.0082	-0.3285	0.6562	-0.3514	0.053	0.1756	-0.0361	0.0314	0.2336	0.0624	0.3081	-5.4765	5.2323	47.3725
191	0.4799	-0.1378	0.3172	1.4305	-0.1413	0.2188	-0.4811	0.0241	-0.3136	0.5412	0.8343	-0.5524	0.0053	-0.1433	0.0237	0.2452	-0.0517	-0.0532	0.1972	0.0821	0.1448	19.0001	9.6318	65.8711
192	0.5505	-0.1267	0.0141	0.2317	0.2467	0.4256	-0.1196	-0.017	0.0404	0.0051	0.0929	-0.3161	0.4771	-0.1068	0.0007	0.352	0.0365	-0.0518	0.2276	0.0803	0.1084	44.4038	6.9237	48.5414
193	6.0583	0.6056	4.039	1.0519	0.8566	3.0082	1.0089	0.0881	-1.1212	0.3154	-0.1132	0.1257	0.3105	0.4497	0.8085	0.0791	0.1352	0.2216	0.0687	-0.0439	-0.1129	35.6577	1.3849	19.3348
194	2.829	-1.1907	2.6165	0.8986	-0.7497	3.4003	-0.2185	-0.5569	1.0498	-0.3237	-0.6072	-0.0073	-0.9518	0.0889	-0.4137	0.3464	0.0915	0.0869	0.054	-0.2209	0.1241	8.4234	99.1823	47.9078
195	0.0232	0.2594	-0.4668	2.202	-3.6935	6.7004	0.0817	-0.3872	0.0768	0.355	-0.0844	-0.3426	-0.5182	0.0733	-0.0564	0.0657	0.0621	-0.0334	0.2282	-0.0305	0.4465	-8.4375	94.4811	22.2799
196	1.7151	0.5823	0.2665	0.2277	-0.1037	0.8543	-0.3465	0.0569	0.6004	-0.6055	0.3105	-0.1995	-0.2016	-0.2107	-0.0186	0.1569	0.0199	-0.0098	0.2186	0.0504	0.1579	10.9889	90.4578	-1.6217
197	0.8532	-0.0204	0.8477	0.7185	-0.3428	1.4691	-0.6066	0.0573	-0.182	0.327	0.6285	0.1131	-0.6738	-0.0836	-0.025	0.1845	-0.0646	0.032	0.2357	-0.0074	0.1098	39.8835	92.962	9.2083
198	0.6882	-0.0771	-0.1976	0.2608	0.1095	0.2279	-0.0209	0.0094	-0.0518	0.0113	0.0033	0.2452	-0.6517	0.3365	0.0021	0.3003	-0.1323	-0.0914	0.1171	0.0195	0.1182	38.2647	98.2347	39.7166

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Selection details
1	X-RAY DIFFRACTION	1	chain A and resid 1:11
2	X-RAY DIFFRACTION	2	chain B and resid 1:11
3	X-RAY DIFFRACTION	3	chain C and resid 1:11
4	X-RAY DIFFRACTION	4	chain D and resid 1:11
5	X-RAY DIFFRACTION	5	chain E and resid 1:11
6	X-RAY DIFFRACTION	6	chain F and resid 1:11
7	X-RAY DIFFRACTION	7	chain G and resid 1:11
8	X-RAY DIFFRACTION	8	chain H and resid 1:11
9	X-RAY DIFFRACTION	9	chain I and resid 1:11
10	X-RAY DIFFRACTION	10	chain J and resid 1:11
11	X-RAY DIFFRACTION	11	chain A and resid 16:20
12	X-RAY DIFFRACTION	12	chain B and resid 16:20
13	X-RAY DIFFRACTION	13	chain C and resid 16:20
14	X-RAY DIFFRACTION	14	chain D and resid 16:20
15	X-RAY DIFFRACTION	15	chain E and resid 16:20
16	X-RAY DIFFRACTION	16	chain F and resid 16:20
17	X-RAY DIFFRACTION	17	chain G and resid 16:20
18	X-RAY DIFFRACTION	18	chain H and resid 16:20
19	X-RAY DIFFRACTION	19	chain I and resid 16:20
20	X-RAY DIFFRACTION	20	chain J and resid 16:20
21	X-RAY DIFFRACTION	21	chain A and resid 26:30
22	X-RAY DIFFRACTION	22	chain B and resid 26:30
23	X-RAY DIFFRACTION	23	chain C and resid 26:30
24	X-RAY DIFFRACTION	24	chain D and resid 26:30
25	X-RAY DIFFRACTION	25	chain E and resid 26:30
26	X-RAY DIFFRACTION	26	chain F and resid 26:30
27	X-RAY DIFFRACTION	27	chain G and resid 26:30
28	X-RAY DIFFRACTION	28	chain H and resid 26:30
29	X-RAY DIFFRACTION	29	chain I and resid 26:30
30	X-RAY DIFFRACTION	30	chain J and resid 26:30
31	X-RAY DIFFRACTION	31	chain A and resid 33:42
32	X-RAY DIFFRACTION	32	chain B and resid 33:42
33	X-RAY DIFFRACTION	33	chain C and resid 33:42
34	X-RAY DIFFRACTION	34	chain D and resid 33:42
35	X-RAY DIFFRACTION	35	chain E and resid 33:42
36	X-RAY DIFFRACTION	36	chain F and resid 33:42
37	X-RAY DIFFRACTION	37	chain G and resid 33:42
38	X-RAY DIFFRACTION	38	chain H and resid 33:42
39	X-RAY DIFFRACTION	39	chain I and resid 33:42
40	X-RAY DIFFRACTION	40	chain J and resid 33:42
41	X-RAY DIFFRACTION	41	chain A and resid 43
42	X-RAY DIFFRACTION	42	chain B and resid 43
43	X-RAY DIFFRACTION	43	chain C and resid 43
44	X-RAY DIFFRACTION	44	chain E and resid 43
45	X-RAY DIFFRACTION	45	chain F and resid 43
46	X-RAY DIFFRACTION	46	chain G and resid 43
47	X-RAY DIFFRACTION	47	chain H and resid 43
48	X-RAY DIFFRACTION	48	chain J and resid 43
49	X-RAY DIFFRACTION	49	chain A and resid 45:49
50	X-RAY DIFFRACTION	50	chain B and resid 45:49
51	X-RAY DIFFRACTION	51	chain C and resid 45:49
52	X-RAY DIFFRACTION	52	chain D and resid 45:49
53	X-RAY DIFFRACTION	53	chain E and resid 45:49
54	X-RAY DIFFRACTION	54	chain F and resid 45:49
55	X-RAY DIFFRACTION	55	chain G and resid 45:49
56	X-RAY DIFFRACTION	56	chain H and resid 45:49
57	X-RAY DIFFRACTION	57	chain I and resid 45:49
58	X-RAY DIFFRACTION	58	chain J and resid 45:49
59	X-RAY DIFFRACTION	59	chain A and resid 51:52
60	X-RAY DIFFRACTION	60	chain B and resid 51:52
61	X-RAY DIFFRACTION	61	chain C and resid 51:52
62	X-RAY DIFFRACTION	62	chain D and resid 51:52
63	X-RAY DIFFRACTION	63	chain E and resid 51:52
64	X-RAY DIFFRACTION	64	chain F and resid 51:52
65	X-RAY DIFFRACTION	65	chain G and resid 51:52
66	X-RAY DIFFRACTION	66	chain H and resid 51:52
67	X-RAY DIFFRACTION	67	chain I and resid 51:52
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