Entry | Database: PDB / ID: 3pg9 |
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Title | Thermotoga maritima DAH7P synthase in complex with inhibitor |
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Components | Phospho-2-dehydro-3-deoxyheptonate aldolase |
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Keywords | Transferase/Transferase inhibitor / Thermotoga maritima / DAH7PS / Shikimate pathway / aromatic biosynthesis / Tyr-bound / Tim barrel / act domain / ferredoxin-like domain / Transferase / Transferase-Transferase inhibitor complex / allosteric regulation |
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Function / homology | Function and homology information
3-deoxy-7-phosphoheptulonate synthase / 3-deoxy-7-phosphoheptulonate synthase activity / aldehyde-lyase activity / chorismate biosynthetic process / aromatic amino acid family biosynthetic process / amino acid biosynthetic processSimilarity search - Function Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 / DAHP synthase ferredoxin-like domain / DAHP synthase ferredoxin-like domain / Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 / DAHP synthetase I/KDSA / DAHP synthetase I family / Aldolase class I / Aldolase-type TIM barrel / Alpha-Beta Plaits / TIM Barrel ...Phospho-2-dehydro-3-deoxyheptonate aldolase; domain 1 / DAHP synthase ferredoxin-like domain / DAHP synthase ferredoxin-like domain / Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 / DAHP synthetase I/KDSA / DAHP synthetase I family / Aldolase class I / Aldolase-type TIM barrel / Alpha-Beta Plaits / TIM Barrel / Alpha-Beta Barrel / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_bacteria.gif) Thermotoga maritima (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.35 Å |
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Authors | Cross, P.J. / Dobson, R.C.J. / Patchett, M.L. / Parker, E.J. |
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Citation | Journal: J.Biol.Chem. / Year: 2011 Title: Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis Authors: Cross, P.J. / Dobson, R.C.J. / Patchett, M.L. / Parker, E.J. |
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History | Deposition | Oct 31, 2010 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | Jan 26, 2011 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jul 13, 2011 | Group: Version format compliance |
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Revision 1.2 | Aug 22, 2012 | Group: Database references |
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Revision 1.3 | Nov 1, 2023 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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