登録情報 | データベース: PDB / ID: 3otj |
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タイトル | A Crystal Structure of Trypsin Complexed with BPTI (Bovine Pancreatic Trypsin Inhibitor) by X-ray/Neutron Joint Refinement |
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要素 | - Cationic trypsin
- Pancreatic trypsin inhibitor
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キーワード | Hydrolase/Hydrolase Inhibitor / Complex / Hydrolase / Inhibitor / Hydrolase-Hydrolase Inhibitor complex |
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機能・相同性 | 機能・相同性情報
trypsinogen activation / negative regulation of serine-type endopeptidase activity / sulfate binding / potassium channel inhibitor activity / negative regulation of platelet aggregation / zymogen binding / molecular function inhibitor activity / negative regulation of thrombin-activated receptor signaling pathway / trypsin / serpin family protein binding ...trypsinogen activation / negative regulation of serine-type endopeptidase activity / sulfate binding / potassium channel inhibitor activity / negative regulation of platelet aggregation / zymogen binding / molecular function inhibitor activity / negative regulation of thrombin-activated receptor signaling pathway / trypsin / serpin family protein binding / serine protease inhibitor complex / digestion / serine-type endopeptidase inhibitor activity / protease binding / endopeptidase activity / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space / metal ion binding類似検索 - 分子機能 : / Pancreatic trypsin inhibitor Kunitz domain / Factor Xa Inhibitor / Proteinase inhibitor I2, Kunitz, conserved site / Pancreatic trypsin inhibitor (Kunitz) family signature. / BPTI/Kunitz family of serine protease inhibitors. / Pancreatic trypsin inhibitor Kunitz domain / Kunitz/Bovine pancreatic trypsin inhibitor domain / Pancreatic trypsin inhibitor (Kunitz) family profile. / Pancreatic trypsin inhibitor Kunitz domain superfamily ...: / Pancreatic trypsin inhibitor Kunitz domain / Factor Xa Inhibitor / Proteinase inhibitor I2, Kunitz, conserved site / Pancreatic trypsin inhibitor (Kunitz) family signature. / BPTI/Kunitz family of serine protease inhibitors. / Pancreatic trypsin inhibitor Kunitz domain / Kunitz/Bovine pancreatic trypsin inhibitor domain / Pancreatic trypsin inhibitor (Kunitz) family profile. / Pancreatic trypsin inhibitor Kunitz domain superfamily / : / Few Secondary Structures / Irregular / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 DEUTERATED WATER / Serine protease 1 / Pancreatic trypsin inhibitor類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Bos taurus (ウシ) |
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手法 | 中性子回折 / X線回折 / NUCLEAR REACTOR / シンクロトロン / 解像度: 2.15 Å |
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データ登録者 | Kawamura, K. / Yamada, T. / Kurihara, K. / Tamada, T. / Kuroki, R. / Tanaka, I. / Takahashi, H. / Niimura, N. |
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引用 | ジャーナル: Acta Crystallogr.,Sect.D / 年: 2011 タイトル: X-ray and neutron protein crystallographic analysis of the trypsin-BPTI complex. 著者: Kawamura, K. / Yamada, T. / Kurihara, K. / Tamada, T. / Kuroki, R. / Tanaka, I. / Takahashi, H. / Niimura, N. |
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履歴 | 登録 | 2010年9月12日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2011年1月26日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2011年7月27日 | Group: Data collection |
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改定 1.3 | 2011年8月21日 | Group: Other |
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改定 1.4 | 2017年11月8日 | Group: Refinement description / カテゴリ: software |
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