- PDB-3i5w: Crystal structure of human alpha-defensin 5 (mutant R13H) -
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Basic information
Entry
Database: PDB / ID: 3i5w
Title
Crystal structure of human alpha-defensin 5 (mutant R13H)
Components
Defensin-5
Keywords
ANTIMICROBIAL PROTEIN / human alpha-defensin 5 / HD5 / antimicrobial peptide / Antibiotic / Antimicrobial / Defensin / Disulfide bond / Fungicide / Secreted
Function / homology
Function and homology information
positive regulation of membrane permeability / Defensins / disruption of plasma membrane integrity in another organism / killing by host of symbiont cells / Alpha-defensins / defense response to fungus / transport vesicle / innate immune response in mucosa / secretory granule / positive regulation of interleukin-8 production ...positive regulation of membrane permeability / Defensins / disruption of plasma membrane integrity in another organism / killing by host of symbiont cells / Alpha-defensins / defense response to fungus / transport vesicle / innate immune response in mucosa / secretory granule / positive regulation of interleukin-8 production / Golgi lumen / antimicrobial humoral immune response mediated by antimicrobial peptide / antibacterial humoral response / midbody / cellular response to lipopolysaccharide / secretory granule lumen / protein homotetramerization / defense response to Gram-negative bacterium / killing of cells of another organism / defense response to Gram-positive bacterium / intracellular membrane-bounded organelle / innate immune response / protein homodimerization activity / extracellular space / extracellular region Similarity search - Function
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