登録情報 | データベース: PDB / ID: 3dfv |
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タイトル | Adjacent GATA DNA binding |
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要素 | - DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3')
- DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3')
- Trans-acting T-cell-specific transcription factor GATA-3
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キーワード | Transcription/DNA / Activator / DNA-binding / Metal-binding / Nucleus / Transcription / Transcription regulation / Zinc / Zinc-finger / Transcription-DNA complex |
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機能・相同性 | 機能・相同性情報
: / nephric duct formation / negative regulation of cell proliferation involved in mesonephros development / regulation of cellular response to X-ray / negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation / negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation / ureter morphogenesis / thymic T cell selection / ureteric bud formation / positive regulation of ureteric bud formation ...: / nephric duct formation / negative regulation of cell proliferation involved in mesonephros development / regulation of cellular response to X-ray / negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation / negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation / ureter morphogenesis / thymic T cell selection / ureteric bud formation / positive regulation of ureteric bud formation / : / HMG box domain binding / positive regulation of thyroid hormone generation / otic vesicle development / anatomical structure formation involved in morphogenesis / pro-T cell differentiation / negative regulation of mammary gland epithelial cell proliferation / nephric duct morphogenesis / interleukin-2 receptor binding / norepinephrine biosynthetic process / cardiac right ventricle morphogenesis / cellular response to interferon-alpha / immune system development / parathyroid gland development / ureter maturation / mesenchymal to epithelial transition / mast cell differentiation / parathyroid hormone secretion / regulation of nephron tubule epithelial cell differentiation / regulation of epithelial cell differentiation / positive regulation of signal transduction / lymphocyte migration / mesonephros development / RUNX1 regulates transcription of genes involved in differentiation of HSCs / positive regulation of T-helper 2 cell cytokine production / regulation of T-helper cell differentiation / ear development / histone methyltransferase binding / Factors involved in megakaryocyte development and platelet production / Estrogen-dependent gene expression / cell activation / positive regulation of interleukin-13 production / positive regulation of interleukin-5 production / pharyngeal system development / sympathetic nervous system development / negative regulation of cell motility / cellular response to BMP stimulus / Ub-specific processing proteases / cell fate determination / positive regulation of transcription regulatory region DNA binding / negative regulation of epithelial to mesenchymal transition / T-helper 2 cell differentiation / aortic valve morphogenesis / cartilage development / regulation of establishment of cell polarity / lens development in camera-type eye / positive regulation of T cell differentiation / embryonic hemopoiesis / ventricular septum development / negative regulation of interleukin-2 production / regulation of neuron projection development / inner ear morphogenesis / positive regulation of interleukin-4 production / E-box binding / cellular response to cytokine stimulus / uterus development / humoral immune response / macrophage differentiation / negative regulation of type II interferon production / negative regulation of cell cycle / T cell differentiation / homeostasis of number of cells / developmental growth / TOR signaling / cell fate commitment / embryonic organ development / cellular response to interleukin-4 / cis-regulatory region sequence-specific DNA binding / negative regulation of endothelial cell apoptotic process / regulation of neuron apoptotic process / cell maturation / regulation of cytokine production / positive regulation of endothelial cell migration / erythrocyte differentiation / phosphatidylinositol 3-kinase/protein kinase B signal transduction / post-embryonic development / thymus development / kidney development / positive regulation of cytokine production / positive regulation of cell differentiation / RNA polymerase II transcription regulatory region sequence-specific DNA binding / axon guidance / neuron migration / response to virus / cell morphogenesis / neuron differentiation / transcription coactivator binding / DNA-binding transcription repressor activity, RNA polymerase II-specific / positive regulation of miRNA transcription / negative regulation of inflammatory response類似検索 - 分子機能 Transcription factor, GATA-2/3 / Transcription factor GATA / GATA-type zinc finger domain. / GATA-type zinc finger domain profile. / zinc finger binding to DNA consensus sequence [AT]GATA[AG] / GATA zinc finger / Zinc finger, GATA-type / Erythroid Transcription Factor GATA-1, subunit A / Erythroid Transcription Factor GATA-1; Chain A / Zinc finger, NHR/GATA-type ...Transcription factor, GATA-2/3 / Transcription factor GATA / GATA-type zinc finger domain. / GATA-type zinc finger domain profile. / zinc finger binding to DNA consensus sequence [AT]GATA[AG] / GATA zinc finger / Zinc finger, GATA-type / Erythroid Transcription Factor GATA-1, subunit A / Erythroid Transcription Factor GATA-1; Chain A / Zinc finger, NHR/GATA-type / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 DNA / DNA (> 10) / Trans-acting T-cell-specific transcription factor GATA-3類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.1 Å |
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データ登録者 | Bates, D.L. / Kim, G.K. / Guo, L. / Chen, L. |
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引用 | ジャーナル: J.Mol.Biol. / 年: 2008 タイトル: Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA. 著者: Bates, D.L. / Chen, Y. / Kim, G. / Guo, L. / Chen, L. |
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履歴 | 登録 | 2008年6月12日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2008年7月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2017年10月25日 | Group: Refinement description / カテゴリ: software |
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