登録情報 | データベース: PDB / ID: 2zl1 |
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タイトル | MP1-p14 Scaffolding complex |
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要素 | - Mitogen-activated protein kinase kinase 1-interacting protein 1
- Mitogen-activated protein-binding protein-interacting protein
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キーワード | PROTEIN BINDING / scaffold / complex / alpha/beta / Endosome / Membrane / Lysosome |
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機能・相同性 | 機能・相同性情報
Energy dependent regulation of mTOR by LKB1-AMPK / MTOR signalling / Regulation of PTEN gene transcription / Macroautophagy / Amino acids regulate mTORC1 / regulation of cell-substrate junction organization / TP53 Regulates Metabolic Genes / mTORC1-mediated signalling / FNIP-folliculin RagC/D GAP / Ragulator complex ...Energy dependent regulation of mTOR by LKB1-AMPK / MTOR signalling / Regulation of PTEN gene transcription / Macroautophagy / Amino acids regulate mTORC1 / regulation of cell-substrate junction organization / TP53 Regulates Metabolic Genes / mTORC1-mediated signalling / FNIP-folliculin RagC/D GAP / Ragulator complex / MAP2K and MAPK activation / protein localization to cell junction / TORC1 signaling / MTOR signalling / Amino acids regulate mTORC1 / fibroblast migration / Energy dependent regulation of mTOR by LKB1-AMPK / kinase activator activity / Macroautophagy / mTORC1-mediated signalling / tertiary granule membrane / positive regulation of TOR signaling / specific granule membrane / positive regulation of TORC1 signaling / Neutrophil degranulation / guanyl-nucleotide exchange factor activity / Regulation of PTEN gene transcription / regulation of cell growth / TP53 Regulates Metabolic Genes / cellular response to amino acid stimulus / MAP2K and MAPK activation / protein localization / late endosome / late endosome membrane / positive regulation of MAPK cascade / molecular adaptor activity / endosome membrane / lysosomal membrane / focal adhesion / Neutrophil degranulation / extracellular exosome / plasma membrane類似検索 - 分子機能 Ragulator complex protein LAMTOR3 / Mitogen-activated protein kinase kinase 1 interacting / Mitogen-activated protein kinase kinase 1 interacting / Ragulator complex protein LAMTOR2-like / Dynein light chain 2a, cytoplasmic / Roadblock/LAMTOR2 domain / Roadblock/LC7 domain / Roadblock/LC7 domain / Beta-Lactamase / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Ragulator complex protein LAMTOR2 / Ragulator complex protein LAMTOR3類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト)
![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 解像度: 2 Å |
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データ登録者 | Schrag, J.D. / Cygler, M. / Munger, C. / Magloire, A. |
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引用 | ジャーナル: J.Mol.Biol. / 年: 2008 タイトル: Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex. 著者: Cui, Q. / Sulea, T. / Schrag, J.D. / Munger, C. / Hung, M.N. / Naim, M. / Cygler, M. / Purisima, E.O. |
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履歴 | 登録 | 2008年4月2日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2008年6月24日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2021年11月10日 | Group: Database references / カテゴリ: database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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改定 1.3 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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