登録情報 | データベース: PDB / ID: 2z4f |
---|
タイトル | Solution structure of the Discoidin Domain of DDR2 |
---|
要素 | Discoidin domain-containing receptor 2 |
---|
キーワード | TRANSFERASE / BETA BARREL |
---|
機能・相同性 | 機能・相同性情報
positive regulation of hepatic stellate cell proliferation / protein tyrosine kinase collagen receptor activity / biomineral tissue development / positive regulation of extracellular matrix disassembly / chondrocyte proliferation / positive regulation of hepatic stellate cell activation / endochondral bone growth / regulation of extracellular matrix disassembly / negative regulation of hydrogen peroxide-mediated programmed cell death / collagen-activated tyrosine kinase receptor signaling pathway ...positive regulation of hepatic stellate cell proliferation / protein tyrosine kinase collagen receptor activity / biomineral tissue development / positive regulation of extracellular matrix disassembly / chondrocyte proliferation / positive regulation of hepatic stellate cell activation / endochondral bone growth / regulation of extracellular matrix disassembly / negative regulation of hydrogen peroxide-mediated programmed cell death / collagen-activated tyrosine kinase receptor signaling pathway / regulation of bone mineralization / positive regulation of fibroblast migration / cellular response to angiotensin / positive regulation of vascular associated smooth muscle cell migration / collagen fibril organization / regulation of tissue remodeling / positive regulation of wound healing / Non-integrin membrane-ECM interactions / positive regulation of collagen biosynthetic process / positive regulation of protein kinase activity / positive regulation of G1/S transition of mitotic cell cycle / positive regulation of osteoblast differentiation / positive regulation of vascular associated smooth muscle cell proliferation / cellular response to transforming growth factor beta stimulus / collagen binding / response to muscle stretch / transmembrane receptor protein tyrosine kinase activity / ossification / receptor protein-tyrosine kinase / positive regulation of DNA-binding transcription factor activity / positive regulation of neuron projection development / peptidyl-tyrosine phosphorylation / positive regulation of fibroblast proliferation / actin cytoskeleton / cellular response to hypoxia / protein autophosphorylation / receptor complex / cell adhesion / apical plasma membrane / focal adhesion / negative regulation of apoptotic process / signal transduction / ATP binding / plasma membrane類似検索 - 分子機能 : / Discoidin domain-containing receptor 1/2, DS-like domain / Coagulation factors 5/8 type C domain (FA58C) signature 2. / Coagulation factors 5/8 type C domain (FA58C) signature 1. / Coagulation factor 5/8 C-terminal domain, discoidin domain / Coagulation factors 5/8 type C domain (FA58C) profile. / F5/8 type C domain / Coagulation factor 5/8 C-terminal domain / Tyrosine-protein kinase, receptor class II, conserved site / Receptor tyrosine kinase class II signature. ...: / Discoidin domain-containing receptor 1/2, DS-like domain / Coagulation factors 5/8 type C domain (FA58C) signature 2. / Coagulation factors 5/8 type C domain (FA58C) signature 1. / Coagulation factor 5/8 C-terminal domain, discoidin domain / Coagulation factors 5/8 type C domain (FA58C) profile. / F5/8 type C domain / Coagulation factor 5/8 C-terminal domain / Tyrosine-protein kinase, receptor class II, conserved site / Receptor tyrosine kinase class II signature. / Galactose-binding domain-like / Galactose-binding-like domain superfamily / Tyrosine-protein kinase, catalytic domain / Tyrosine kinase, catalytic domain / Tyrosine protein kinases specific active-site signature. / Tyrosine-protein kinase, active site / Protein tyrosine and serine/threonine kinase / Serine-threonine/tyrosine-protein kinase, catalytic domain / Jelly Rolls / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | 溶液NMR / torsion angle dynamics |
---|
データ登録者 | Ichikawa, O. / Osawa, M. / Nishida, N. / Goshima, N. / Nomura, N. / Shimada, I. |
---|
引用 | ジャーナル: Embo J. / 年: 2007 タイトル: Structural basis of the collagen-binding mode of discoidin domain receptor 2 著者: Ichikawa, O. / Osawa, M. / Nishida, N. / Goshima, N. / Nomura, N. / Shimada, I. |
---|
履歴 | 登録 | 2007年6月16日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2007年9月4日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2011年7月13日 | Group: Version format compliance |
---|
改定 1.2 | 2022年3月16日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_spectrometer ...database_2 / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
---|
|
---|