Entry Database : PDB / ID : 2y2f Structure visualization Downloads & linksTitle Crystal structure of Yersinia pestis YopH in complex with an aminooxy- containing platform compound for inhibitor design ComponentsPROTEIN-TYROSINE PHOSPHATASE YOPH Details Keywords HYDROLASE / PROTEIN TYROSINE PHOSPHATASEFunction / homology Function and homology informationFunction Domain/homology Component
Protein-tyrosine phosphatase, YopH, N-terminal / Protein-tyrosine phosphatase, YopH, N-terminal domain superfamily / YopH, N-terminal / Type III secreted modular tyrosine phosphatase, SptP/YopH / Protein tyrosine phosphatase superfamily / Protein-Tyrosine Phosphatase; Chain A / Protein tyrosine phosphatase, catalytic domain / PTP type protein phosphatase domain profile. / Protein-tyrosine phosphatase / Tyrosine-specific protein phosphatase, PTPase domain ... Protein-tyrosine phosphatase, YopH, N-terminal / Protein-tyrosine phosphatase, YopH, N-terminal domain superfamily / YopH, N-terminal / Type III secreted modular tyrosine phosphatase, SptP/YopH / Protein tyrosine phosphatase superfamily / Protein-Tyrosine Phosphatase; Chain A / Protein tyrosine phosphatase, catalytic domain / PTP type protein phosphatase domain profile. / Protein-tyrosine phosphatase / Tyrosine-specific protein phosphatase, PTPase domain / Protein-tyrosine phosphatase, catalytic / Protein tyrosine phosphatase, catalytic domain motif / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Protein-tyrosine phosphatase-like / Alpha-Beta Complex / Alpha Beta Similarity search - Domain/homologyBiological species YERSINIA PESTIS (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.78 Å DetailsAuthors Lountos, G.T. / Bahta, M. / Dyas, B. / Ulrich, R.G. / Waugh, D.S. / Burke, T.R. CitationJournal : J.Med.Chem. / Year : 2011Title : Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (Yoph) Phosphatase.Authors : Bahta, M. / Lountos, G.T. / Dyas, B. / Kim, S. / Ulrich, R.G. / Waugh, D.S. / Burke, T.R. History Deposition Dec 14, 2010 Deposition site : PDBE / Processing site : PDBERevision 1.0 Mar 16, 2011 Provider : repository / Type : Initial releaseRevision 1.1 Sep 28, 2011 Group : Database references / Version format complianceRevision 1.2 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Show all Show less