Entry | Database: PDB / ID: 2wlw |
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Title | Structure of the N-terminal capsid domain of HIV-2 |
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Components | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE |
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Keywords | ISOMERASE / ROTAMASE / RHESUS MACAQUE TRIM-CYP |
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Function / homology | Function and homology information
negative regulation of protein K48-linked ubiquitination / regulation of apoptotic signaling pathway / cell adhesion molecule production / heparan sulfate binding / regulation of viral genome replication / leukocyte chemotaxis / endothelial cell activation / negative regulation of stress-activated MAPK cascade / cyclosporin A binding / protein peptidyl-prolyl isomerization ...negative regulation of protein K48-linked ubiquitination / regulation of apoptotic signaling pathway / cell adhesion molecule production / heparan sulfate binding / regulation of viral genome replication / leukocyte chemotaxis / endothelial cell activation / negative regulation of stress-activated MAPK cascade / cyclosporin A binding / protein peptidyl-prolyl isomerization / negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway / positive regulation of protein dephosphorylation / activation of protein kinase B activity / neutrophil chemotaxis / negative regulation of protein phosphorylation / peptidylprolyl isomerase / peptidyl-prolyl cis-trans isomerase activity / negative regulation of protein kinase activity / platelet activation / platelet aggregation / integrin binding / protein folding / positive regulation of NF-kappaB transcription factor activity / cellular response to oxidative stress / positive regulation of MAPK cascade / response to hypoxia / positive regulation of protein phosphorylation / apoptotic process / extracellular region / nucleus / cytoplasm / cytosolSimilarity search - Function Cyclophilin-like / Cyclophilin / Cyclophilin-type peptidyl-prolyl cis-trans isomerase / Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site / Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. / Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain profile. / Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain / Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD / Cyclophilin-like domain superfamily / Beta Barrel / Mainly BetaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_mammal.gif) MACACA MULATTA (Rhesus monkey) |
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Method | X-RAY DIFFRACTION / OTHER / Resolution: 1.5 Å |
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Authors | Price, A.J. / Marzetta, F. / Lammers, M. / Ylinen, L.M.J. / Schaller, T. / Wilson, S.J. / Towers, G.J. / James, L.C. |
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Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2009 Title: Active Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp Authors: Price, A.J. / Marzetta, F. / Lammers, M. / Ylinen, L.M.J. / Schaller, T. / Wilson, S.J. / Towers, G.J. / James, L.C. |
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History | Deposition | Jun 26, 2009 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Sep 22, 2009 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jun 30, 2011 | Group: Version format compliance |
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Revision 1.2 | Jul 13, 2011 | Group: Version format compliance |
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Revision 1.3 | May 8, 2024 | Group: Data collection / Database references / Other Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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