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TitleActive Site Remodelling Switches HIV Specificity of Antiretroviral Trimcyp
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 16, Page 1036-, Year 2009
Publish dateJun 26, 2009 (structure data deposition date)
AuthorsPrice, A.J. / Marzetta, F. / Lammers, M. / Ylinen, L.M.J. / Schaller, T. / Wilson, S.J. / Towers, G.J. / James, L.C.
External linksNat. Struct. Mol. Biol. / PubMed:19767750
MethodsX-ray diffraction
Resolution1.25 - 1.5 Å
Structure data

PDB-2wlv:
Structure of the N-terminal capsid domain of HIV-2
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-2wlw:
Structure of the N-terminal capsid domain of HIV-2
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 2 (isolate d194)
  • macaca mulatta (Rhesus monkey)
KeywordsVIRAL PROTEIN / RNA-BINDING / CAPSID PROTEIN / VIRAL NUCLEOPROTEIN / HIV / AIDS / HIV-2 / HIV-1 / ISOMERASE / ROTAMASE / RHESUS MACAQUE TRIM-CYP

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