erythromycin 12-hydroxylase / oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen / macrolide biosynthetic process / cholest-4-en-3-one 26-monooxygenase activity / steroid hydroxylase activity / cholesterol catabolic process / monooxygenase activity / NADP binding / iron ion binding / heme binding 類似検索 - 分子機能
解像度: 2→89.8 Å / Cor.coef. Fo:Fc: 0.94 / Cor.coef. Fo:Fc free: 0.912 / SU B: 4.007 / SU ML: 0.115 / 交差検証法: THROUGHOUT / ESU R: 0.266 / ESU R Free: 0.202 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. THE PDB STARTS FROM A.A. 19 SINCE THERE WAS NO INTERPRETABLE ELECTRON DENSITY FOR PREVIOUS RESIDUES
Rfactor
反射数
%反射
Selection details
Rfree
0.23202
1115
5 %
RANDOM
Rwork
0.18341
-
-
-
obs
0.18587
21300
81.77 %
-
溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: BABINET MODEL WITH MASK