Entry Database : PDB / ID : 2vwb Structure visualization Downloads & linksTitle Structure of the archaeal Kae1-Bud32 fusion protein MJ1130: a model for the eukaryotic EKC-KEOPS subcomplex involved in transcription and telomere homeostasis. ComponentsPUTATIVE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE Details Keywords HYDROLASE / EKC / KAE1 / BUD32 / KEOPS / MJ1130 / PROTEASE / TELOMERE / METALLOPROTEASEFunction / homology Function and homology informationFunction Domain/homology Component
N6-L-threonylcarbamoyladenine synthase / N(6)-L-threonylcarbamoyladenine synthase activity / EKC/KEOPS complex / tRNA threonylcarbamoyladenosine modification / protein serine/threonine/tyrosine kinase activity / metalloendopeptidase activity / non-specific serine/threonine protein kinase / iron ion binding / protein serine kinase activity / protein serine/threonine kinase activity ... N6-L-threonylcarbamoyladenine synthase / N(6)-L-threonylcarbamoyladenine synthase activity / EKC/KEOPS complex / tRNA threonylcarbamoyladenosine modification / protein serine/threonine/tyrosine kinase activity / metalloendopeptidase activity / non-specific serine/threonine protein kinase / iron ion binding / protein serine kinase activity / protein serine/threonine kinase activity / zinc ion binding / ATP binding / cytoplasm Similarity search - Function Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein / tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote / Serine/threonine-protein kinase Bud32 / Peptidase M22, conserved site / Glycoprotease family signature. / Kae1/TsaD family / Gcp-like domain / tRNA N6-adenosine threonylcarbamoyltransferase / RIO1 family / ATPase, nucleotide binding domain ... Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein / tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote / Serine/threonine-protein kinase Bud32 / Peptidase M22, conserved site / Glycoprotease family signature. / Kae1/TsaD family / Gcp-like domain / tRNA N6-adenosine threonylcarbamoyltransferase / RIO1 family / ATPase, nucleotide binding domain / ATPase, nucleotide binding domain / Nucleotidyltransferase; domain 5 / Tyrosine protein kinases specific active-site signature. / Tyrosine-protein kinase, active site / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta Similarity search - Domain/homology PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein Similarity search - ComponentBiological species METHANOCALDOCOCCUS JANNASCHII (archaea)Method X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution : 3.05 Å DetailsAuthors Hecker, A. / Lopreiato, R. / Graille, M. / Collinet, B. / Forterre, P. / Domenico, L. / van Tilbeurgh, H. CitationJournal : Embo J. / Year : 2008Title : Structure of the Archaeal Kae1/Bud32 Fusion Protein Mj1130: A Model for the Eukaryotic Ekc/Keops SubcomplexAuthors : Hecker, A. / Lopreiato, R. / Graille, M. / Collinet, B. / Forterre, P. / Libri, D. / Van Tilbeurgh, H. History Deposition Jun 20, 2008 Deposition site : PDBE / Processing site : PDBERevision 1.0 Aug 19, 2008 Provider : repository / Type : Initial releaseRevision 1.1 Jan 27, 2016 Group : Database references / Derived calculations ... Database references / Derived calculations / Source and taxonomy / Version format compliance Revision 1.2 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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