Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase activity / monoamine oxidase / phenylethylamine catabolic process / positive regulation of dopamine metabolic process / response to aluminum ion / negative regulation of serotonin secretion / response to selenium ion / primary-amine oxidase / dopamine catabolic process ...Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase activity / monoamine oxidase / phenylethylamine catabolic process / positive regulation of dopamine metabolic process / response to aluminum ion / negative regulation of serotonin secretion / response to selenium ion / primary-amine oxidase / dopamine catabolic process / aliphatic amine oxidase activity / primary methylamine oxidase activity / mitochondrial envelope / hydrogen peroxide biosynthetic process / response to corticosterone / substantia nigra development / response to toxic substance / flavin adenine dinucleotide binding / response to ethanol / mitochondrial outer membrane / response to lipopolysaccharide / electron transfer activity / response to xenobiotic stimulus / neuronal cell body / dendrite / mitochondrion / identical protein binding Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 288 / Source method: isolated from a natural source / Formula: H2O
Nonpolymer details
THE COMPOUND USED FOR CO-CRYSTALLIZATION IS THE MAO B INHIBITOR BENZYLHYDRAZINE (BZZ), WHICH IS ...THE COMPOUND USED FOR CO-CRYSTALLIZATION IS THE MAO B INHIBITOR BENZYLHYDRAZINE (BZZ), WHICH IS CHEMICALLY MODIFIED BY THE ENZYME TO A PRODUCT THAT IS SIMILAR TO TOLUENE.
-
Experimental details
-
Experiment
Experiment
Method: X-RAY DIFFRACTION
-
Sample preparation
Crystal
Density Matthews: 2.7 Å3/Da / Density % sol: 55.25 % / Description: NONE
Crystal grow
Details: 12% PEG4000 100MM ADA PH 6.5 70MM LITHIUM SULPHATE