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TitleStructural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B
Journal, issue, pagesBiochemistry, Vol. 47, Page 5616-, Year 2008
Publish dateApr 9, 2008 (structure data deposition date)
AuthorsBinda, C. / Wang, J. / Li, M. / Hubalek, F. / Mattevi, A. / Edmondson, D.E.
External linksBiochemistry / PubMed:18426226
MethodsX-ray diffraction
Resolution2.3 - 2.4 Å
Structure data

PDB-2vrl:
Structure of human MAO B in complex with benzylhydrazine
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2vrm:
Structure of human MAO B in complex with phenyethylhydrazine
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-MBN:
TOLUENE

ChemComp-HOH:
WATER

ChemComp-PYJ:
PHENYLETHANE

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / FAD / FLAVIN / MEMBRANE / HYDRAZINE / ACETYLATION / FLAVOPROTEIN / MITOCHONDRION / TRANSMEMBRANE / INHIBITOR BINDING / MEMBRANE PROTEIN / MONOAMINE OXIDASE

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