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Yorodumi- PDB-2snv: THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON... -
+Open data
-Basic information
Entry | Database: PDB / ID: 2snv | ||||||
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Title | THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON WITH OTHER CHYMOTRYPSIN-LIKE SERINE PROTEINASE STRUCTURES | ||||||
Components | SINDBIS VIRUS COAT PROTEIN | ||||||
Keywords | VIRAL PROTEIN | ||||||
Function / homology | Function and homology information icosahedral viral capsid, spike / togavirin / T=4 icosahedral viral capsid / ubiquitin-like protein ligase binding / symbiont-mediated suppression of host toll-like receptor signaling pathway / clathrin-dependent endocytosis of virus by host cell / host cell cytoplasm / membrane fusion / serine-type endopeptidase activity / fusion of virus membrane with host endosome membrane ...icosahedral viral capsid, spike / togavirin / T=4 icosahedral viral capsid / ubiquitin-like protein ligase binding / symbiont-mediated suppression of host toll-like receptor signaling pathway / clathrin-dependent endocytosis of virus by host cell / host cell cytoplasm / membrane fusion / serine-type endopeptidase activity / fusion of virus membrane with host endosome membrane / viral envelope / host cell nucleus / virion attachment to host cell / host cell plasma membrane / virion membrane / structural molecule activity / proteolysis / RNA binding / membrane Similarity search - Function | ||||||
Biological species | Sindbis virus | ||||||
Method | X-RAY DIFFRACTION / Resolution: 2.8 Å | ||||||
Authors | Tong, L. / Rossmann, M.G. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1993 Title: Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures. Authors: Tong, L. / Wengler, G. / Rossmann, M.G. #1: Journal: Acta Crystallogr.,Sect.A / Year: 1992 Title: The Structure Determination of Sindbis Virus Core Protein Using Isomorphous Replacement and Molecular Replacement Averaging between Two Crystal Forms Authors: Tong, L. / Choi, H.-K. / Minor, W. / Rossmann, M.G. #2: Journal: Nature / Year: 1991 Title: Structure of Sindbis Virus Core Protein Reveals a Chymotrypsin-Like Serine Proteinase and the Organization of the Virion Authors: Choi, H.-K. / Tong, L. / Minor, W. / Dumas, P. / Boege, U. / Rossmann, M.G. / Wengler, G. | ||||||
History |
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Remark 700 | SHEET THE STRAND ASSIGNMENTS OF THE SHEET RECORDS ARE TENTATIVE. |
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2snv.cif.gz | 39.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2snv.ent.gz | 27.7 KB | Display | PDB format |
PDBx/mmJSON format | 2snv.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/sn/2snv ftp://data.pdbj.org/pub/pdb/validation_reports/sn/2snv | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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-Components
#1: Protein | Mass: 16545.631 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Sindbis virus / Genus: Alphavirus / References: UniProt: P03316 |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.69 Å3/Da / Density % sol: 54.34 % | ||||||||||||||||||||
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Crystal grow | *PLUS pH: 8.3 / Method: vapor diffusion, hanging drop | ||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Reflection | *PLUS Highest resolution: 2.8 Å / Num. obs: 3779 / Num. measured all: 17265 / Rmerge(I) obs: 0.063 |
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-Processing
Software |
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Refinement | Rfactor Rwork: 0.2 / Rfactor obs: 0.2 / Highest resolution: 2.8 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Highest resolution: 2.8 Å
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Refine LS restraints |
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Refinement | *PLUS Highest resolution: 2.8 Å / Lowest resolution: 6 Å / Num. reflection obs: 3229 / Rfactor obs: 0.2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS Biso mean: 27.8 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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