登録情報 | データベース: PDB / ID: 2nps |
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タイトル | Crystal Structure of the Early Endosomal SNARE Complex |
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要素 | - Syntaxin 13
![](img/lk-wikipe.gif) - Syntaxin-6
![](img/lk-wikipe.gif) - Vesicle transport through interaction with t-SNAREs homolog 1A
- Vesicle-associated membrane protein 4
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キーワード | TRANSPORT PROTEIN (運搬体タンパク質) / Vesicle fusion (小胞融合) / SNARE complex / early endosomal SNARE complex / syntaxin 6 / syntaxin 13 / Vti1a / VAMP4 |
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機能・相同性 | 機能・相同性情報
regulation of Golgi to plasma membrane protein transport / : / synaptic vesicle to endosome fusion / Retrograde transport at the Trans-Golgi-Network / : / Intra-Golgi traffic / Retrograde transport at the Trans-Golgi-Network / postsynaptic recycling endosome / vesicle fusion with Golgi apparatus / : ...regulation of Golgi to plasma membrane protein transport / : / synaptic vesicle to endosome fusion / Retrograde transport at the Trans-Golgi-Network / : / Intra-Golgi traffic / Retrograde transport at the Trans-Golgi-Network / postsynaptic recycling endosome / vesicle fusion with Golgi apparatus / : / Retrograde transport at the Trans-Golgi-Network / Golgi ribbon formation / Intra-Golgi traffic / Golgi vesicle transport / Golgi to vacuole transport / 小胞融合 / vesicle docking / clathrin-coated vesicle membrane / voluntary musculoskeletal movement / SNARE complex / Golgi to plasma membrane protein transport / Cargo recognition for clathrin-mediated endocytosis / SNAP receptor activity / intra-Golgi vesicle-mediated transport / Clathrin-mediated endocytosis / protein targeting to vacuole / neuron projection terminus / endocytic recycling / phagophore assembly site / retrograde transport, endosome to Golgi / SNARE complex assembly / syntaxin binding / クラスリン / cholesterol efflux / regulation of synaptic vesicle endocytosis / autophagosome assembly / オートファゴソーム / 細胞内膜系 / endoplasmic reticulum to Golgi vesicle-mediated transport / phagocytic vesicle / SNARE binding / trans-Golgi network membrane / intracellular protein transport / ゴルジ体 / ER to Golgi transport vesicle membrane / terminal bouton / recycling endosome / synaptic vesicle membrane / オートファジー / microtubule cytoskeleton organization / cellular response to type II interferon / recycling endosome membrane / regulation of protein localization / シナプス小胞 / late endosome membrane / early endosome membrane / vesicle / membrane => GO:0016020 / エンドソーム / protein stabilization / エンドソーム / 脂質ラフト / ゴルジ体 / neuronal cell body / endoplasmic reticulum membrane / perinuclear region of cytoplasm / ゴルジ体 / 細胞膜 / 核質 / 細胞膜 / 細胞質基質類似検索 - 分子機能 Vesicle-associated membrane protein 4 / Syntaxin 6, N-terminal / Syntaxin 6, N-terminal / Syntaxin-like protein / GOSR2/Membrin/Bos1 / Snare region anchored in the vesicle membrane C-terminus / Vesicle transport v-SNARE, N-terminal / Vesicle transport v-SNARE, N-terminal domain superfamily / Vesicle transport v-SNARE protein N-terminus / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #110 ...Vesicle-associated membrane protein 4 / Syntaxin 6, N-terminal / Syntaxin 6, N-terminal / Syntaxin-like protein / GOSR2/Membrin/Bos1 / Snare region anchored in the vesicle membrane C-terminus / Vesicle transport v-SNARE, N-terminal / Vesicle transport v-SNARE, N-terminal domain superfamily / Vesicle transport v-SNARE protein N-terminus / Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #110 / Synaptobrevin signature. / Syntaxin N-terminal domain / Syntaxin, N-terminal domain / Syntaxin / SNARE domain / Synaptobrevin-like / Syntaxin/epimorphin, conserved site / Synaptobrevin / Syntaxin / epimorphin family signature. / v-SNARE, coiled-coil homology domain / v-SNARE coiled-coil homology domain profile. / SNARE / Helical region found in SNAREs / t-SNARE coiled-coil homology domain profile. / Target SNARE coiled-coil homology domain / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 Syntaxin-12 / Syntaxin-6 / Syntaxin-12 / Vesicle-associated membrane protein 4 / Vesicle transport through interaction with t-SNAREs homolog 1A類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) ![](data/taxo/icon/Mus_musculus_S.png) Mus musculus (ハツカネズミ)
![](img/tx_mammal.gif) ![](data/taxo/icon/Rattus_norvegicus_S.png) Rattus norvegicus (ドブネズミ)
![](img/tx_human.gif) Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.5 Å |
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データ登録者 | Zwilling, D. / Cypionka, A. / Pohl, W.H. / Fasshauer, D. / Walla, P.J. / Wahl, M.C. / Jahn, R. |
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引用 | ジャーナル: Embo J. / 年: 2007 タイトル: Early endosomal SNAREs form a structurally conserved SNARE complex and fuse liposomes with multiple topologies 著者: Zwilling, D. / Cypionka, A. / Pohl, W.H. / Fasshauer, D. / Walla, P.J. / Wahl, M.C. / Jahn, R. |
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履歴 | 登録 | 2006年10月30日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2006年12月26日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2017年10月18日 | Group: Advisory / Refinement description / カテゴリ: pdbx_unobs_or_zero_occ_atoms / software / Item: _software.name |
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改定 1.4 | 2023年10月25日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_unobs_or_zero_occ_atoms / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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