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- PDB-2n9g: Solution structure of the bromodomain of Trypanosoma brucei Bromo... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2n9g | ||||||
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Title | Solution structure of the bromodomain of Trypanosoma brucei Bromodomain Factor 2(BDF2) | ||||||
![]() | Putative uncharacterized protein | ||||||
![]() | GENE REGULATION | ||||||
Function / homology | ![]() lysine-acetylated histone binding / histone binding / chromatin remodeling / regulation of transcription by RNA polymerase II / nucleus Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | SOLUTION NMR / DGSA-distance geometry simulated annealing | ||||||
Model details | lowest energy, model1 | ||||||
![]() | Yang, X. | ||||||
![]() | ![]() Title: Solution structure of the bromodomain of Trypanosoma brucei Bromodomain Factor 2(BDF2) Authors: Yang, X. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 790.1 KB | Display | ![]() |
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PDB format | ![]() | 673.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 535.9 KB | Display | ![]() |
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Full document | ![]() | 730.9 KB | Display | |
Data in XML | ![]() | 54.5 KB | Display | |
Data in CIF | ![]() | 63.6 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data | |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein | Mass: 12723.268 Da / Num. of mol.: 1 / Fragment: bromo domain, UNP residues 1-111 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() Strain: TREU927 / Gene: Tb10.6k15.3240 / Production host: ![]() ![]() |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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NMR experiment | Type: 2D 1H-15N ![]() |
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Sample preparation
Details | Contents: 150 mM sodium chloride-1, 20 mM sodium phosphate-2, 1 mM DTT-3, 1 mM EDTA-4, 90% H2O/10% D2O Solvent system: 90% H2O/10% D2O | |||||||||||||||
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Sample |
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Sample conditions | pH: 6.8 / Pressure: ambient / Temperature: 298 K |
-NMR measurement
NMR spectrometer | Type: Bruker DMX / Manufacturer: Bruker / Model: DMX / Field strength: 500 MHz |
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Processing
NMR software |
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Refinement | Method: DGSA-distance geometry simulated annealing / Software ordinal: 1 | |||||||||
NMR representative | Selection criteria: lowest energy | |||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 500 / Conformers submitted total number: 20 / Representative conformer: 1 |