- PDB-2lag: Structure of the 44 kDa complex of interferon-alpha2 with the ext... -
+
データを開く
IDまたはキーワード:
読み込み中...
-
基本情報
登録情報
データベース: PDB / ID: 2lag
タイトル
Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY
要素
Interferon alpha-2
Interferon alpha/beta receptor 2
キーワード
IMMUNE SYSTEM / interferon / receptor
機能・相同性
機能・相同性情報
type I interferon receptor activity / type I interferon binding / type I interferon receptor binding / B cell activation involved in immune response / JAK pathway signal transduction adaptor activity / negative regulation of interleukin-5 production / response to interferon-beta / natural killer cell activation involved in immune response / negative regulation of interleukin-13 production / negative regulation of T cell differentiation ...type I interferon receptor activity / type I interferon binding / type I interferon receptor binding / B cell activation involved in immune response / JAK pathway signal transduction adaptor activity / negative regulation of interleukin-5 production / response to interferon-beta / natural killer cell activation involved in immune response / negative regulation of interleukin-13 production / negative regulation of T cell differentiation / response to interferon-alpha / negative regulation of T-helper 2 cell cytokine production / T cell activation involved in immune response / host-mediated suppression of symbiont invasion / cell surface receptor signaling pathway via STAT / TRAF6 mediated IRF7 activation / type I interferon-mediated signaling pathway / cytokine binding / response to exogenous dsRNA / humoral immune response / Regulation of IFNA/IFNB signaling / cell surface receptor signaling pathway via JAK-STAT / cellular response to interferon-beta / cytokine activity / Evasion by RSV of host interferon responses / cellular response to virus / response to virus / Interferon alpha/beta signaling / cell-cell signaling / Factors involved in megakaryocyte development and platelet production / : / defense response to virus / adaptive immune response / Potential therapeutics for SARS / cell surface receptor signaling pathway / receptor complex / inflammatory response / negative regulation of gene expression / negative regulation of DNA-templated transcription / apoptotic process / protein kinase binding / SARS-CoV-2 activates/modulates innate and adaptive immune responses / extracellular space / extracellular region / plasma membrane 類似検索 - 分子機能
Interferon alpha, beta and delta family signature. / Interferon alpha, beta and delta. / Interferon alpha/beta/delta / Interferon alpha/beta domain / Interferon/interleukin receptor domain / Interferon-alpha/beta receptor, fibronectin type III / : / Tissue factor / Growth Hormone; Chain: A; - #10 / Four-helical cytokine-like, core ...Interferon alpha, beta and delta family signature. / Interferon alpha, beta and delta. / Interferon alpha/beta/delta / Interferon alpha/beta domain / Interferon/interleukin receptor domain / Interferon-alpha/beta receptor, fibronectin type III / : / Tissue factor / Growth Hormone; Chain: A; - #10 / Four-helical cytokine-like, core / Growth Hormone; Chain: A; / Fibronectin type III / Fibronectin type III superfamily / Immunoglobulin-like fold / Immunoglobulins / Up-down Bundle / Immunoglobulin-like / Sandwich / Mainly Beta / Mainly Alpha 類似検索 - ドメイン・相同性