登録情報 | データベース: PDB / ID: 2krn |
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タイトル | High resolution structure of the second SH3 domain of CD2AP |
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要素 | CD2-associated protein |
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キーワード | SIGNALING PROTEIN / protein / SH3 domain |
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機能・相同性 | 機能・相同性情報
neurotrophin signaling pathway / response to glial cell derived neurotrophic factor / regulation of receptor-mediated endocytosis / negative regulation of small GTPase mediated signal transduction / transforming growth factor beta1 production / localization of cell / Rab protein signal transduction / negative regulation of transforming growth factor beta1 production / vascular endothelial growth factor receptor binding / slit diaphragm ...neurotrophin signaling pathway / response to glial cell derived neurotrophic factor / regulation of receptor-mediated endocytosis / negative regulation of small GTPase mediated signal transduction / transforming growth factor beta1 production / localization of cell / Rab protein signal transduction / negative regulation of transforming growth factor beta1 production / vascular endothelial growth factor receptor binding / slit diaphragm / response to transforming growth factor beta / podocyte differentiation / vesicle organization / immunological synapse formation / endothelium development / nerve growth factor signaling pathway / cell-cell adhesion mediated by cadherin / collateral sprouting / protein heterooligomerization / renal albumin absorption / phosphatidylinositol 3-kinase regulatory subunit binding / glomerulus development / membrane organization / filopodium assembly / cell-cell junction organization / podosome / clathrin binding / maintenance of blood-brain barrier / nuclear envelope lumen / glucose import / cell leading edge / filamentous actin / neurotrophin TRK receptor signaling pathway / endocytic vesicle / centriolar satellite / protein secretion / lymph node development / adipose tissue development / stress-activated MAPK cascade / ruffle / ERK1 and ERK2 cascade / actin filament polymerization / phosphatidylinositol 3-kinase/protein kinase B signal transduction / trans-Golgi network membrane / liver development / kidney development / actin filament organization / cell periphery / actin filament / positive regulation of protein secretion / regulation of actin cytoskeleton organization / synapse organization / response to insulin / response to virus / protein catabolic process / neuromuscular junction / regulation of synaptic plasticity / lipid metabolic process / fibrillar center / cell-cell adhesion / response to wounding / beta-catenin binding / positive regulation of protein localization to nucleus / SH3 domain binding / male gonad development / neuron projection development / actin filament binding / cell-cell junction / protein transport / cell migration / late endosome / T cell receptor signaling pathway / actin binding / gene expression / cell cortex / growth cone / proteasome-mediated ubiquitin-dependent protein catabolic process / vesicle / negative regulation of neuron apoptotic process / response to oxidative stress / cell population proliferation / cell differentiation / neuron projection / inflammatory response / cadherin binding / cell division / axon / dendrite / protein-containing complex binding / apoptotic process / perinuclear region of cytoplasm / protein-containing complex / identical protein binding / plasma membrane / cytosol / cytoplasm類似検索 - 分子機能 CD2-associated protein, first SH3 domain / CD2-associated protein, second SH3 domain / CD2-associated protein, third SH3 domain / : / Variant SH3 domain / SH3 Domains / SH3 domain / SH3 type barrels. / Src homology 3 domains / SH3-like domain superfamily ...CD2-associated protein, first SH3 domain / CD2-associated protein, second SH3 domain / CD2-associated protein, third SH3 domain / : / Variant SH3 domain / SH3 Domains / SH3 domain / SH3 type barrels. / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Mus musculus (ハツカネズミ) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Ortega Roldan, J. / Azuaga, A.I. / van Nuland, N.A.J. |
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引用 | ジャーナル: To be Published タイトル: Solution Structure, Dynamics and Thermodynamics of the three SH3 domains of CD2AP 著者: Ortega Roldan, J.L. / Blackledge, M. / van Nuland, N.A.J. / Azuaga, A.I. |
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履歴 | 登録 | 2009年12月21日 | 登録サイト: BMRB / 処理サイト: PDBJ |
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改定 1.0 | 2011年1月12日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2024年5月1日 | Group: Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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