登録情報 データベース : PDB / ID : 2knh 構造の表示 ダウンロードとリンクタイトル The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide 要素Protein CBFA2T1 Transcription factor 12 詳細キーワード TRANSCRIPTION REGULATOR / AML1-ETO / eTAFH / HEB / DNA-binding / Metal-binding / Nucleus / Proto-oncogene / Transcription / Transcription regulation / Zinc-finger / Developmental protein / Phosphoprotein機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
response to gonadotropin-releasing hormone / cAMP response element binding / HMG box domain binding / bHLH transcription factor binding / NGF-stimulated transcription / muscle organ development / negative regulation of fat cell differentiation / Myogenesis / E-box binding / SMAD binding ... response to gonadotropin-releasing hormone / cAMP response element binding / HMG box domain binding / bHLH transcription factor binding / NGF-stimulated transcription / muscle organ development / negative regulation of fat cell differentiation / Myogenesis / E-box binding / SMAD binding / cis-regulatory region sequence-specific DNA binding / positive regulation of neuron differentiation / nuclear matrix / RNA polymerase II transcription regulator complex / transcription corepressor activity / sequence-specific double-stranded DNA binding / RUNX1 regulates transcription of genes involved in differentiation of HSCs / nervous system development / gene expression / DNA-binding transcription activator activity, RNA polymerase II-specific / DNA-binding transcription factor binding / cell differentiation / DNA-binding transcription factor activity, RNA polymerase II-specific / nuclear speck / immune response / protein heterodimerization activity / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / intracellular membrane-bounded organelle / negative regulation of DNA-templated transcription / DNA-templated transcription / positive regulation of gene expression / chromatin / regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus / metal ion binding / cytoplasm 類似検索 - 分子機能 TAFH/NHR1 domain / Protein CBFA2T1 / CBFA2T family / NHR2-like / NHR2 domain like / TAFH/NHR1 domain superfamily / NHR1 homology to TAF / TAFH/NHR1 domain profile. / TAF homology / TAFH/NHR1 ... TAFH/NHR1 domain / Protein CBFA2T1 / CBFA2T family / NHR2-like / NHR2 domain like / TAFH/NHR1 domain superfamily / NHR1 homology to TAF / TAFH/NHR1 domain profile. / TAF homology / TAFH/NHR1 / MYND finger / Zinc finger, MYND-type / Zinc finger MYND-type signature. / Zinc finger MYND-type profile. / Helix-loop-helix DNA-binding domain / Helix-loop-helix DNA-binding domain superfamily / helix loop helix domain / Myc-type, basic helix-loop-helix (bHLH) domain / Myc-type, basic helix-loop-helix (bHLH) domain profile. / Four Helix Bundle (Hemerythrin (Met), subunit A) / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 溶液NMR / simulated annealing 詳細Model details lowest energy, model 1 データ登録者 Park, S. / Cierpicki, T. / Tonelli, M. / Bushweller, J.H. 引用ジャーナル : Blood / 年 : 2009タイトル : Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.著者 : Park, S. / Chen, W. / Cierpicki, T. / Tonelli, M. / Cai, X. / Speck, N.A. / Bushweller, J.H. 履歴 登録 2009年8月25日 登録サイト : BMRB / 処理サイト : RCSB改定 1.0 2009年10月6日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2020年2月26日 Group : Data collection / Database references / Otherカテゴリ : database_2 / pdbx_database_status ... database_2 / pdbx_database_status / pdbx_nmr_spectrometer / struct_ref_seq_dif Item : _pdbx_database_status.status_code_cs / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details改定 1.3 2024年5月1日 Group : Data collection / Database references / カテゴリ : chem_comp_atom / chem_comp_bond / database_2Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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