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- PDB-2gwf: Structure of a USP8-NRDP1 complex -

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Basic information

Entry
Database: PDB / ID: 2gwf
TitleStructure of a USP8-NRDP1 complex
Components
  • RING finger protein 41
  • Ubiquitin carboxyl-terminal hydrolase 8
KeywordsHYDROLASE/LIGASE / PROTEIN-PROTEIN COMPLEX / E3 LIGASE / PROTEIN UBIQUITINATION / HYDROLASE / PROTEASE / UBL CONJUGATION PATHWAY / Structural Genomics / Structural Genomics Consortium / SGC / HYDROLASE-LIGASE COMPLEX
Function / homology
Function and homology information


interleukin-3 receptor binding / erythropoietin receptor binding / endoplasmic reticulum tubular network / negative regulation of lysosomal protein catabolic process / acrosomal membrane / regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / regulation of protein catabolic process at postsynapse, modulating synaptic transmission / endosome organization / protein K48-linked deubiquitination / K48-linked deubiquitinase activity ...interleukin-3 receptor binding / erythropoietin receptor binding / endoplasmic reticulum tubular network / negative regulation of lysosomal protein catabolic process / acrosomal membrane / regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / regulation of protein catabolic process at postsynapse, modulating synaptic transmission / endosome organization / protein K48-linked deubiquitination / K48-linked deubiquitinase activity / regulation of reactive oxygen species metabolic process / cellular response to dexamethasone stimulus / positive regulation of amyloid fibril formation / protein K63-linked deubiquitination / K63-linked deubiquitinase activity / mitotic cytokinesis / regulation of MAPK cascade / protein deubiquitination / extrinsic apoptotic signaling pathway / protein autoubiquitination / negative regulation of cell migration / Regulation of FZD by ubiquitination / Downregulation of ERBB2:ERBB3 signaling / regulation of protein stability / proteasomal protein catabolic process / autophagy / cellular response to nerve growth factor stimulus / Negative regulation of MET activity / receptor tyrosine kinase binding / RING-type E3 ubiquitin transferase / positive regulation of reactive oxygen species metabolic process / small GTPase binding / protein polyubiquitination / ubiquitin-protein transferase activity / positive regulation of canonical Wnt signaling pathway / positive regulation of protein catabolic process / ubiquitin protein ligase activity / regulation of protein localization / Antigen processing: Ubiquitination & Proteasome degradation / midbody / ubiquitin-dependent protein catabolic process / early endosome / Ras protein signal transduction / ubiquitinyl hydrolase 1 / cysteine-type deubiquitinase activity / Ub-specific processing proteases / endosome membrane / postsynaptic density / cadherin binding / negative regulation of cell population proliferation / protein domain specific binding / cysteine-type endopeptidase activity / glutamatergic synapse / perinuclear region of cytoplasm / zinc ion binding / identical protein binding / nucleus / plasma membrane / cytosol / cytoplasm
Similarity search - Function
E3 ubiquitin-protein ligase NRDP1 / NRDP1, C-terminal / USP8 interacting / : / USP8 WW domain / Zinc finger, SIAH-type / Zinc finger SIAH-type profile. / USP8 dimerisation domain / USP8 dimerisation domain / Rhodanese-like domain ...E3 ubiquitin-protein ligase NRDP1 / NRDP1, C-terminal / USP8 interacting / : / USP8 WW domain / Zinc finger, SIAH-type / Zinc finger SIAH-type profile. / USP8 dimerisation domain / USP8 dimerisation domain / Rhodanese-like domain / Oxidized Rhodanese; domain 1 / : / Zinc finger, C3HC4 type (RING finger) / Rhodanese-like domain / Rhodanese domain profile. / Rhodanese-like domain superfamily / Rhodanese-like domain / Ubiquitin specific protease (USP) domain signature 2. / Ubiquitin specific protease (USP) domain signature 1. / Ubiquitin specific protease, conserved site / Peptidase C19, ubiquitin carboxyl-terminal hydrolase / Ubiquitin carboxyl-terminal hydrolase / Ubiquitin specific protease domain / Ubiquitin specific protease (USP) domain profile. / Zinc finger, RING-type, conserved site / Zinc finger RING-type signature. / Ring finger / Papain-like cysteine peptidase superfamily / Zinc finger RING-type profile. / Zinc finger, RING-type / Zinc finger, RING/FYVE/PHD-type / 3-Layer(aba) Sandwich / Alpha Beta
Similarity search - Domain/homology
Ubiquitin carboxyl-terminal hydrolase 8 / E3 ubiquitin-protein ligase NRDP1
Similarity search - Component
Biological speciesHomo sapiens (human)
MethodX-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution: 2.3 Å
AuthorsWalker, J.R. / Avvakumov, G.V. / Xue, S. / Newman, E.M. / Butler-Cole, C. / Finerty Jr., P.J. / Weigelt, J. / Sundstrom, M. / Arrowsmith, C.H. / Edwards, A.M. ...Walker, J.R. / Avvakumov, G.V. / Xue, S. / Newman, E.M. / Butler-Cole, C. / Finerty Jr., P.J. / Weigelt, J. / Sundstrom, M. / Arrowsmith, C.H. / Edwards, A.M. / Bochkarev, A. / Dhe-Paganon, S. / Structural Genomics Consortium (SGC)
CitationJournal: J.Biol.Chem. / Year: 2006
Title: Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
Authors: Avvakumov, G.V. / Walker, J.R. / Xue, S. / Finerty Jr., P.J. / Mackenzie, F. / Newman, E.M. / Dhe-Paganon, S.
History
DepositionMay 4, 2006Deposition site: RCSB / Processing site: RCSB
Revision 1.0Jun 6, 2006Provider: repository / Type: Initial release
Revision 1.1May 1, 2008Group: Version format compliance
Revision 1.2Jul 13, 2011Group: Advisory / Version format compliance
Revision 1.3Feb 14, 2024Group: Data collection / Database references
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

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Assembly

Deposited unit
A: Ubiquitin carboxyl-terminal hydrolase 8
B: RING finger protein 41
C: Ubiquitin carboxyl-terminal hydrolase 8
D: RING finger protein 41
E: Ubiquitin carboxyl-terminal hydrolase 8
F: RING finger protein 41


Theoretical massNumber of molelcules
Total (without water)98,2936
Polymers98,2936
Non-polymers00
Water3,927218
1
A: Ubiquitin carboxyl-terminal hydrolase 8
B: RING finger protein 41


Theoretical massNumber of molelcules
Total (without water)32,7642
Polymers32,7642
Non-polymers00
Water362
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
2
C: Ubiquitin carboxyl-terminal hydrolase 8
D: RING finger protein 41


Theoretical massNumber of molelcules
Total (without water)32,7642
Polymers32,7642
Non-polymers00
Water362
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
3
E: Ubiquitin carboxyl-terminal hydrolase 8
F: RING finger protein 41


Theoretical massNumber of molelcules
Total (without water)32,7642
Polymers32,7642
Non-polymers00
Water362
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)76.111, 67.094, 99.275
Angle α, β, γ (deg.)90.00, 91.12, 90.00
Int Tables number4
Space group name H-MP1211

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Components

#1: Protein Ubiquitin carboxyl-terminal hydrolase 8 / Ubiquitin thioesterase 8 / Ubiquitin-specific processing protease 8 / Deubiquitinating enzyme 8 / hUBPy


Mass: 17783.152 Da / Num. of mol.: 3 / Fragment: Rhodanase domain, residues 181-318
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: USP8, KIAA0055, UBPY / Plasmid: pET28-LIC / Species (production host): Escherichia coli / Production host: Escherichia coli BL21 (bacteria) / Strain (production host): BL21 / References: UniProt: P40818, EC: 3.1.2.15
#2: Protein RING finger protein 41


Mass: 14981.053 Da / Num. of mol.: 3 / Fragment: USP8 interaction domain, residues 193-317
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: RNF41 / Plasmid: pET28-LIC / Species (production host): Escherichia coli / Production host: Escherichia coli BL21 (bacteria) / Strain (production host): BL21
References: UniProt: Q9H4P4, Ligases; Forming carbon-nitrogen bonds; Acid-amino-acid ligases (peptide synthases)
#3: Water ChemComp-HOH / water


Mass: 18.015 Da / Num. of mol.: 218 / Source method: isolated from a natural source / Formula: H2O

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 2.58 Å3/Da / Density % sol: 52.28 %
Crystal growTemperature: 298 K / Method: vapor diffusion, hanging drop / pH: 6.5
Details: 12% PEG5000 MME, 0.1 M bis-Tris, 1 mM DTT, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 298.0K

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Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: ALS / Beamline: 8.2.1 / Wavelength: 0.98 Å
DetectorType: ADSC QUANTUM 210 / Detector: CCD / Date: Jan 21, 2006
RadiationProtocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.98 Å / Relative weight: 1
ReflectionResolution: 2.3→30 Å / Num. all: 41906 / Num. obs: 41906 / % possible obs: 93.4 % / Observed criterion σ(F): 0 / Observed criterion σ(I): -3 / Redundancy: 4 % / Rsym value: 0.069 / Net I/σ(I): 21.98
Reflection shellResolution: 2.3→2.38 Å / Redundancy: 4 % / Mean I/σ(I) obs: 3.15 / Num. unique all: 4352 / Rsym value: 0.46 / % possible all: 97.8

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Processing

Software
NameVersionClassification
REFMAC5.2.0019refinement
ADSCdata collection
HKL-2000data scaling
SOLVEphasing
RefinementMethod to determine structure: SAD / Resolution: 2.3→30 Å / Cor.coef. Fo:Fc: 0.942 / Cor.coef. Fo:Fc free: 0.928 / SU B: 12.467 / SU ML: 0.156 / TLS residual ADP flag: LIKELY RESIDUAL / Cross valid method: THROUGHOUT / ESU R: 0.333 / ESU R Free: 0.228 / Stereochemistry target values: MAXIMUM LIKELIHOOD / Details: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS
RfactorNum. reflection% reflectionSelection details
Rfree0.23704 2093 5 %RANDOM
Rwork0.2061 ---
obs0.20767 39572 93.17 %-
Solvent computationIon probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.4 Å / Solvent model: BABINET MODEL WITH MASK
Displacement parametersBiso mean: 29.84 Å2
Baniso -1Baniso -2Baniso -3
1-2.7 Å20 Å2-1.11 Å2
2---1.62 Å20 Å2
3----1.12 Å2
Refinement stepCycle: LAST / Resolution: 2.3→30 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms6170 0 0 218 6388
Refine LS restraints
Refine-IDTypeDev idealDev ideal targetNumber
X-RAY DIFFRACTIONr_bond_refined_d0.0060.0226298
X-RAY DIFFRACTIONr_angle_refined_deg1.1911.9528551
X-RAY DIFFRACTIONr_dihedral_angle_1_deg5.5935770
X-RAY DIFFRACTIONr_dihedral_angle_2_deg36.88824.599287
X-RAY DIFFRACTIONr_dihedral_angle_3_deg15.209151112
X-RAY DIFFRACTIONr_dihedral_angle_4_deg16.1591539
X-RAY DIFFRACTIONr_chiral_restr0.0690.2958
X-RAY DIFFRACTIONr_gen_planes_refined0.0020.024716
X-RAY DIFFRACTIONr_nbd_refined0.1680.22771
X-RAY DIFFRACTIONr_nbtor_refined0.2880.24305
X-RAY DIFFRACTIONr_xyhbond_nbd_refined0.1140.2330
X-RAY DIFFRACTIONr_symmetry_vdw_refined0.1370.249
X-RAY DIFFRACTIONr_symmetry_hbond_refined0.1630.214
X-RAY DIFFRACTIONr_mcbond_it0.74634009
X-RAY DIFFRACTIONr_mcangle_it1.20146259
X-RAY DIFFRACTIONr_scbond_it1.43952703
X-RAY DIFFRACTIONr_scangle_it2.23472292
LS refinement shellResolution: 2.3→2.359 Å / Total num. of bins used: 20
RfactorNum. reflection% reflection
Rfree0.301 162 -
Rwork0.223 2995 -
obs--96.6 %
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
15.50637.5327-2.221227.7615-1.64084.7076-0.0823-0.09930.36450.37690.38141.2147-0.8022-0.9559-0.29910.01880.1225-0.03430.18550.0110.0898-24.172125.571285.7964
210.695-4.0748-0.82411.85281.272337.236-0.30130.48130.4555-0.38780.5970.6386-2.5944-0.6849-0.29570.29750.0282-0.1272-0.0359-0.0280.0616-20.302333.745791.0782
35.69940.4929-1.30063.8428-1.11356.6829-0.00360.1454-0.2063-0.2345-0.043-0.27150.04680.39940.04670.0820.01270.00030.0907-0.00480.0915-8.016819.463685.0331
41.497-2.04452.71484.4786-0.530110.91130.23160.1983-0.20810.22090.3798-0.05851.08880.7166-0.61150.1522-0.0133-0.07170.00460.050.1448-7.70938.968196.1571
55.7455-1.0771-0.05353.63360.04995.8751-0.0567-0.27440.03380.13380.0343-0.08740.03710.13820.02230.1290.0086-0.00110.07340.00720.0752-3.632419.455397.8278
61.55241.45810.52952.2475-0.50412.31990.06060.0066-0.2007-0.1192-0.04440.19050.1061-0.449-0.01630.08880.0117-0.00980.0867-0.02820.1175-18.058715.101890.1308
71.8485-0.3577-0.19113.773-0.57975.3329-0.041-0.2364-0.13310.51920.12360.2685-0.1777-0.3667-0.08260.08270.02810.04080.08160.01710.1133-17.769315.566596.9625
811.43362.29424.21647.0341-1.561711.7638-0.25470.75580.1033-0.48250.0315-0.1258-0.3920.04670.22320.13880.0706-0.05160.0636-0.00770.0335-15.651425.463176.4458
916.4027-8.77563.907110.1598-3.24645.55880.12590.66010.3041-0.1107-0.6975-1.29290.19310.8340.5716-0.0448-0.02270.03940.10720.10510.20426.857217.473891.7105
104.74953.0982-3.697615.6673-8.0678.0162-0.07630.29650.0427-0.2830.42450.46530.0466-0.2674-0.34820.09650.0002-0.00110.1175-0.00150.10146.769920.352594.1176
1111.39011.74741.4993.1710.52073.452-0.00940.2144-0.5705-0.0450.0547-0.16870.40680.347-0.04540.10640.03520.01940.01270.05350.135118.27957.24795.9897
126.49350.0894-2.23126.1131-0.78476.108-0.0442-0.324-0.24960.7010.0047-0.16060.19980.23920.03940.0876-0.0093-0.05940.10570.03240.070412.887217.4169104.5819
134.89170.28062.25886.7873-0.37883.9911-0.0335-0.11150.47380.0799-0.0497-0.0606-0.5492-0.16180.08310.16060.0085-0.03840.0129-0.03930.09098.730130.688199.4902
143.51981.19680.648412.19874.16153.4212-0.18690.2841-0.2561-0.44180.0959-0.33580.00330.40590.091-0.02540.01190.00530.13010.04240.140519.435719.666790.9954
154.0315-0.4676-0.25823.8315-0.59372.71380.083-0.25560.11870.17360.0859-0.5394-0.11280.6842-0.16890.0484-0.02320.01650.14980.01730.123121.079822.957297.5178
165.3015-0.0221.68453.16121.54464.040.06640.00480.13730.099-0.1524-0.17790.05410.35560.0860.10290.01220.02720.10610.04570.165315.718821.288695.2842
174.17141.2801-3.186315.02358.01267.95830.08450.2659-0.6561-0.17240.17050.21460.89330.0821-0.2550.1238-0.0017-0.0280.1022-0.07290.0943-18.3284-6.500251.5905
180.8176-1.66234.79463.8091-8.134534.18980.24330.5955-0.69030.23190.5150.97652.0767-1.0594-0.75840.2017-0.20710.06990.162-0.14490.1829-27.6421-7.105656.8156
194.1394-0.321-1.018510.27-6.24411.3386-0.11640.240.4571-0.1860.098-0.24-0.4216-0.35120.01840.06280.01020.01230.141-0.06920.0766-22.051211.770851.7725
204.22390.48931.57787.17324.57515.46240.01880.0847-0.0078-0.4786-0.0668-0.0268-0.3068-0.17520.0480.0820.02360.00370.1858-0.01030.085-22.918110.825253.2301
216.4772-1.5958-0.09564.11562.0823.6022-0.1010.08980.14150.15520.2971-0.1112-0.0470.1133-0.19610.02670.00270.01090.1315-0.05510.0801-21.003414.936264.5465
222.7230.7851-0.29672.64610.87994.0359-0.01310.2106-0.10560.09270.305-0.34660.20630.1871-0.2920.00910.0437-0.00580.1238-0.09210.1466-14.03135.134258.6821
232.44330.7881.59972.5212.97689.4155-0.0213-0.0541-0.08750.24220.2562-0.39280.14880.4336-0.23490.03330.0273-0.00410.0616-0.07310.1227-15.68442.674259.928
2418.8934-1.4371.756317.83769.96899.3668-0.12450.3429-0.4438-0.0508-0.15990.4069-0.3835-0.23350.28440.0445-0.0380.00610.1289-0.04910.002-25.19680.121442.9523
25254.9915-53.9648-92.363111.804924.25391.1037-4.89490.41696.12360.70063.5977-0.18920.7036-1.85791.29720.1901-0.1143-0.1985-0.29270.10520.5168-37.662850.587468.0926
264.87051.63832.520219.71424.86248.4371-0.24280.21130.8878-1.3416-0.17990.9685-1.0156-0.20720.4227-0.00980.0882-0.00620.11260.09920.1579-38.984539.112557.2254
2720.34283.23557.82544.80930.76374.3077-0.02770.5058-0.3045-0.17890.2217-0.0828-0.07510.0428-0.19410.07620.01420.01650.1445-0.01060.0899-30.954121.93661.2067
286.3411-4.4745-0.81686.55813.51612.6463-0.09070.32220.9567-0.10950.0926-0.5568-0.31340.2702-0.0018-0.0388-0.0443-0.01370.06830.11170.2603-25.168938.480460.9964
297.50614.00121.957211.5883-4.59916.19850.2221-0.30580.54460.5876-0.06810.0282-0.3302-0.0289-0.1540.04380.03970.02580.1037-0.07460.1139-29.669930.26371.0007
3011.6929-1.41933.05324.30021.21983.157-0.0106-0.1518-0.52740.16490.02270.05710.1692-0.1641-0.0120.02910.00870.05370.14110.0270.0691-38.63618.552568.8791
313.4496-0.3669-0.4433.19790.15862.10740.14850.21950.4582-0.0504-0.14540.1095-0.2336-0.2353-0.00310.02730.0605-0.04180.14260.01690.148-39.051531.924161.1703
325.29750.2322-0.79043.25840.25971.7261-0.0394-0.02460.39240.0473-0.00270.0676-0.2682-0.25450.04210.01740.0461-0.05090.1770.03090.1675-36.836929.345863.3376
3313.8540.0833-3.25532.79813.64775.57210.2980.05380.9292-0.0884-0.04321.0074-0.5594-0.6735-0.25480.2620.19220.14920.06410.05520.0799-9.548449.782779.6678
3422.072622.488510.577223.963915.362325.06320.4930.04940.58690.13650.49861.890.8873-1.2871-0.99160.06250.3242-0.02460.41250.0850.1466-16.048341.431775.9995
354.5082-0.8569-1.61823.9861-0.77786.60570.0765-0.0407-0.09390.12660.0088-0.1956-0.08220.2398-0.08520.10020.00490.01730.0873-0.01150.12062.442938.052478.0364
361.03820.4245-1.2043.3110.35973.5134-0.03840.1538-0.0993-0.2269-0.02010.0181-0.3863-0.07060.05850.10140.02380.01140.09540.01280.05062.977638.882168.2249
370.31552.68151.195122.793910.15844.5272-0.1209-0.36460.6216-0.05350.6311-0.7121-1.54080.8284-0.51020.3855-0.09750.18110.0956-0.01330.01797.182253.942877.8143
383.66392.263.22213.2313-1.010412.66660.26160.35020.4209-0.51110.2052-0.4179-0.98590.1078-0.46680.24050.00670.11420.01540.02540.07345.738248.939168.7669
393.737-1.99291.11496.6211-1.26210.04150.48290.60770.313-0.9273-0.09170.1267-0.99950.2045-0.39120.1620.04670.0754-0.03770.06710.0158-0.05547.691167.8073
403.5509-1.3305-0.33813.08-1.0717.8877-0.2284-0.4284-0.78990.29890.2472-0.3432-0.329-0.4043-0.01890.10340.08560.12340.03420.03140.1046-5.976840.60289.0471
4120.825-13.1713-13.139112.32038.445417.9031-0.50460.2682-1.33910.1468-0.01340.3651.03040.41210.5180.04570.01040.01090.0734-0.00340.130720.76845.982770.7194
4211.80674.36-3.84047.4552-6.08834.98040.08740.0550.41020.22240.06440.1645-0.2849-0.1756-0.15180.0866-0.01030.04610.1065-0.04450.07418.857423.650669.7814
431.73890.1418-0.33817.84511.5241.3317-0.1252-0.00590.022-0.02910.2164-0.1582-0.02180.3274-0.0912-0.0295-0.00270.03440.2029-0.03320.127825.001218.931867.524
449.11410.0742-0.09434.7437-3.75526.4451-0.00750.66750.0375-0.1638-0.039-0.25780.02880.29730.04660.05520.01080.05520.1518-0.0290.110113.798719.667859.272
456.83193.7578-0.400110.1846-4.12598.44780.04390.15220.0946-0.32070.00660.40370.1567-0.5012-0.0505-0.0085-0.0059-0.0110.1286-0.05590.1079-0.026318.904963.6165
4612.15860.90494.22816.9047-2.03716.85340.2325-0.4946-0.1650.3993-0.05590.06650.0169-0.5033-0.17660.0320.01720.09070.10710.01260.096710.315911.229671.5598
473.8965-0.62991.20541.58310.97375.6170.05910.252-0.5094-0.1680.11240.04070.34080.0942-0.17150.07310.01450.0570.11850.02460.183211.968810.485266.4164
485.5577-1.6752-0.0913.72510.76793.690.05120.0897-0.29850.1410.04110.02750.1058-0.1559-0.09230.0485-0.02390.02110.17890.01920.209312.126215.977769.887
Refinement TLS group
IDRefine-IDRefine TLS-IDAuth asym-IDLabel asym-IDAuth seq-IDLabel seq-ID
1X-RAY DIFFRACTION1AA180 - 19219 - 31
2X-RAY DIFFRACTION2AA193 - 19932 - 38
3X-RAY DIFFRACTION3AA200 - 22339 - 62
4X-RAY DIFFRACTION4AA224 - 23363 - 72
5X-RAY DIFFRACTION5AA234 - 24973 - 88
6X-RAY DIFFRACTION6AA250 - 27489 - 113
7X-RAY DIFFRACTION7AA275 - 301114 - 140
8X-RAY DIFFRACTION8AA302 - 315141 - 154
9X-RAY DIFFRACTION9BB197 - 21114 - 28
10X-RAY DIFFRACTION10BB212 - 22229 - 39
11X-RAY DIFFRACTION11BB223 - 24440 - 61
12X-RAY DIFFRACTION12BB245 - 26062 - 77
13X-RAY DIFFRACTION13BB261 - 27478 - 91
14X-RAY DIFFRACTION14BB275 - 28292 - 99
15X-RAY DIFFRACTION15BB283 - 298100 - 115
16X-RAY DIFFRACTION16BB299 - 317116 - 134
17X-RAY DIFFRACTION17CC180 - 19019 - 29
18X-RAY DIFFRACTION18CC191 - 19930 - 38
19X-RAY DIFFRACTION19CC200 - 21139 - 50
20X-RAY DIFFRACTION20CC212 - 22651 - 65
21X-RAY DIFFRACTION21CC227 - 24766 - 86
22X-RAY DIFFRACTION22CC248 - 28287 - 121
23X-RAY DIFFRACTION23CC283 - 304122 - 143
24X-RAY DIFFRACTION24CC305 - 313144 - 152
25X-RAY DIFFRACTION25DD192 - 1989 - 15
26X-RAY DIFFRACTION26DD199 - 21116 - 28
27X-RAY DIFFRACTION27DD212 - 22229 - 39
28X-RAY DIFFRACTION28DD223 - 24440 - 61
29X-RAY DIFFRACTION29DD245 - 25762 - 74
30X-RAY DIFFRACTION30DD258 - 27175 - 88
31X-RAY DIFFRACTION31DD272 - 29589 - 112
32X-RAY DIFFRACTION32DD296 - 317113 - 134
33X-RAY DIFFRACTION33EE180 - 19019 - 29
34X-RAY DIFFRACTION34EE191 - 19630 - 35
35X-RAY DIFFRACTION35EE197 - 22636 - 65
36X-RAY DIFFRACTION36EE227 - 26166 - 100
37X-RAY DIFFRACTION37EE262 - 272101 - 111
38X-RAY DIFFRACTION38EE273 - 282112 - 121
39X-RAY DIFFRACTION39EE283 - 301122 - 140
40X-RAY DIFFRACTION40EE302 - 316141 - 155
41X-RAY DIFFRACTION41FF196 - 21013 - 27
42X-RAY DIFFRACTION42FF211 - 22328 - 40
43X-RAY DIFFRACTION43FF224 - 24441 - 61
44X-RAY DIFFRACTION44FF245 - 25862 - 75
45X-RAY DIFFRACTION45FF259 - 27276 - 89
46X-RAY DIFFRACTION46FF273 - 28090 - 97
47X-RAY DIFFRACTION47FF281 - 30098 - 117
48X-RAY DIFFRACTION48FF301 - 317118 - 134

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