- PDB-4bu1: Crystal structure of Rad4 BRCT1,2 in complex with a Crb2 phosphop... -
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Basic information
Entry
Database: PDB / ID: 4bu1
Title
Crystal structure of Rad4 BRCT1,2 in complex with a Crb2 phosphopeptide
Components
DNA REPAIR PROTEIN RHP9
S-M CHECKPOINT CONTROL PROTEIN RAD4
Keywords
REPLICATION / TOPBP1 / DNA DAMAGE CHECKPOINT
Function / homology
Function and homology information
SUMOylation of transcription factors / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / mitotic spindle pole body / mitotic DNA damage checkpoint signaling / chromatin-protein adaptor activity / DNA replication preinitiation complex / mitotic DNA replication checkpoint signaling / regulation of double-strand break repair via homologous recombination / negative regulation of DNA replication / mitotic G2 DNA damage checkpoint signaling ...SUMOylation of transcription factors / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / mitotic spindle pole body / mitotic DNA damage checkpoint signaling / chromatin-protein adaptor activity / DNA replication preinitiation complex / mitotic DNA replication checkpoint signaling / regulation of double-strand break repair via homologous recombination / negative regulation of DNA replication / mitotic G2 DNA damage checkpoint signaling / DNA replication initiation / signaling adaptor activity / methylated histone binding / DNA damage checkpoint signaling / mitotic spindle / site of double-strand break / histone binding / chromatin / positive regulation of transcription by RNA polymerase II / identical protein binding / nucleus / cytosol Similarity search - Function
DNA repair protein Crb2, Tudor domain / DNA repair protein Crb2 Tudor domain / twin BRCT domain / : / : / BRCT domain / BRCA1 C Terminus (BRCT) domain / breast cancer carboxy-terminal domain / BRCT domain profile. / BRCT domain ...DNA repair protein Crb2, Tudor domain / DNA repair protein Crb2 Tudor domain / twin BRCT domain / : / : / BRCT domain / BRCA1 C Terminus (BRCT) domain / breast cancer carboxy-terminal domain / BRCT domain profile. / BRCT domain / BRCT domain superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology
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