Entry Database : PDB / ID : 2cfa Structure visualization Downloads & linksTitle Structure of viral flavin-dependant thymidylate synthase ThyX Components(THYMIDYLATE SYNTHASE) x 2 Details Keywords TRANSFERASE / FDTS / TSCP / FLAVIN DEPENDENT THYMIDYLATE SYNTHASE FAD / FLAVOPROTEIN / NUCLEOTIDE BIOSYNTHESIS / METHYLTRANSFERASEFunction / homology Function and homology informationFunction Domain/homology Component
thymidylate synthase (FAD) / thymidylate synthase (FAD) activity / thymidylate synthase activity / dTMP biosynthetic process / dTTP biosynthetic process / NADPH binding / flavin adenine dinucleotide binding / methylation Similarity search - Function Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3070 / Gyrase A; domain 2 - #170 / Thymidylate synthase ThyX / Thymidylate synthase ThyX superfamily / Thymidylate synthase complementing protein / Flavin-dependent thymidylate synthase (thyX) domain profile. / Gyrase A; domain 2 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / 2-Layer Sandwich ... Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #3070 / Gyrase A; domain 2 - #170 / Thymidylate synthase ThyX / Thymidylate synthase ThyX superfamily / Thymidylate synthase complementing protein / Flavin-dependent thymidylate synthase (thyX) domain profile. / Gyrase A; domain 2 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Up-down Bundle / 2-Layer Sandwich / Mainly Alpha / Alpha Beta Similarity search - Domain/homologyBiological species PARAMECIUM BURSARIA CHLORELLA VIRUS 1Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.3 Å DetailsAuthors Graziani, S. / Bernauer, J. / Skouloubris, S. / Graille, M. / Zhou, C.-Z. / Marchand, C. / Decottignies, P. / van Tilbeurgh, H. / Myllykallio, H. / Liebl, U. CitationJournal : J.Biol.Chem. / Year : 2006Title : Catalytic Mechanism and Structure of Viral Flavin-Dependent Thymidylate Synthase Thyx.Authors : Graziani, S. / Bernauer, J. / Skouloubris, S. / Graille, M. / Zhou, C.-Z. / Marchand, C. / Decottignies, P. / Van Tilbeurgh, H. / Myllykallio, H. / Liebl, U. History Deposition Feb 17, 2006 Deposition site : PDBE / Processing site : PDBERevision 1.0 May 16, 2006 Provider : repository / Type : Initial releaseRevision 1.1 Jul 17, 2013 Group : Atomic model / Database references ... Atomic model / Database references / Derived calculations / Non-polymer description / Other / Source and taxonomy / Structure summary / Version format compliance Revision 1.2 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flag / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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