登録情報 データベース : PDB / ID : 2c74 構造の表示 ダウンロードとリンクタイトル 14-3-3 Protein Eta (Human) Complexed to Peptide 要素14-3-3 PROTEIN ETA CONSENSUS PEPTIDE MODE 1 FOR 14-3-3 PROTEINS 詳細キーワード SIGNALING PROTEIN/PEPTIDE / SIGNALING PROTEIN-PEPTIDE COMPLEX / 14-3-3 / PHOSPHOSERINE / PHOSPHORYLATION機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
glucocorticoid catabolic process / cerebellar granule cell to Purkinje cell synapse / nuclear receptor-mediated glucocorticoid signaling pathway / negative regulation of dendrite morphogenesis / nuclear glucocorticoid receptor binding / membrane depolarization during action potential / regulation of neuron differentiation / intercalated disc / sodium channel regulator activity / Activation of BAD and translocation to mitochondria ... glucocorticoid catabolic process / cerebellar granule cell to Purkinje cell synapse / nuclear receptor-mediated glucocorticoid signaling pathway / negative regulation of dendrite morphogenesis / nuclear glucocorticoid receptor binding / membrane depolarization during action potential / regulation of neuron differentiation / intercalated disc / sodium channel regulator activity / Activation of BAD and translocation to mitochondria / Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / regulation of sodium ion transport / SARS-CoV-1 targets host intracellular signalling and regulatory pathways / RHO GTPases activate PKNs / insulin-like growth factor receptor binding / substantia nigra development / presynaptic modulation of chemical synaptic transmission / Transcriptional and post-translational regulation of MITF-M expression and activity / Translocation of SLC2A4 (GLUT4) to the plasma membrane / TP53 Regulates Metabolic Genes / intracellular protein transport / regulation of synaptic plasticity / intracellular protein localization / presynapse / actin binding / transmembrane transporter binding / protein heterodimerization activity / protein domain specific binding / positive regulation of DNA-templated transcription / enzyme binding / signal transduction / mitochondrion / extracellular exosome / identical protein binding / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 14-3-3 domain / Delta-Endotoxin; domain 1 / 14-3-3 proteins signature 2. / 14-3-3 protein, conserved site / 14-3-3 proteins signature 1. / 14-3-3 protein / 14-3-3 homologues / 14-3-3 domain / 14-3-3 domain superfamily / 14-3-3 protein ... 14-3-3 domain / Delta-Endotoxin; domain 1 / 14-3-3 proteins signature 2. / 14-3-3 protein, conserved site / 14-3-3 proteins signature 1. / 14-3-3 protein / 14-3-3 homologues / 14-3-3 domain / 14-3-3 domain superfamily / 14-3-3 protein / Up-down Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 HOMO SAPIENS (ヒト)synthetic construct (人工物) 手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.7 Å 詳細データ登録者 Elkins, J.M. / Yang, X. / Smee, C.E.A. / Johansson, C. / Sundstrom, M. / Edwards, A. / Weigelt, J. / Arrowsmith, C. / Doyle, D.A. 引用ジャーナル : Proc. Natl. Acad. Sci. U.S.A. / 年 : 2006タイトル : Structural basis for protein-protein interactions in the 14-3-3 protein family.著者 : Yang, X. / Lee, W.H. / Sobott, F. / Papagrigoriou, E. / Robinson, C.V. / Grossmann, J.G. / Sundstrom, M. / Doyle, D.A. / Elkins, J.M. 履歴 登録 2005年11月17日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2005年12月2日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Advisory / Refinement description / Version format compliance改定 1.2 2018年1月31日 Group : Database references / Source and taxonomy / カテゴリ : citation / entity_src_genItem : _citation.journal_abbrev / _citation.page_last ... _citation.journal_abbrev / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _entity_src_gen.pdbx_host_org_cell_line / _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id / _entity_src_gen.pdbx_host_org_scientific_name 改定 1.3 2019年10月9日 Group : Data collection / Derived calculations / Other / カテゴリ : pdbx_database_status / struct_connItem : _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flag改定 1.4 2020年7月29日 Group : Derived calculations / Source and taxonomy / カテゴリ : pdbx_entity_src_syn / struct_siteItem : _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id改定 1.5 2023年12月13日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession改定 1.6 2024年11月20日 Group : Structure summaryカテゴリ : pdbx_entry_details / pdbx_modification_featureItem : _pdbx_entry_details.has_protein_modification
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