登録情報 データベース : PDB / ID : 1zuc 構造の表示 ダウンロードとリンクタイトル Progesterone receptor ligand binding domain in complex with the nonsteroidal agonist tanaproget 要素Progesterone receptor 詳細 キーワード HORMONE/GROWTH FACTOR / progesterone receptor / nonsteroidal agonist / tanaproget / progesterone / hormone / HORMONE-GROWTH FACTOR COMPLEX機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
glandular epithelial cell maturation / tertiary branching involved in mammary gland duct morphogenesis / ovulation from ovarian follicle / negative regulation of phosphorylation / paracrine signaling / maintenance of protein location in nucleus / regulation of epithelial cell proliferation / nuclear steroid receptor activity / lung alveolus development / progesterone receptor signaling pathway ... glandular epithelial cell maturation / tertiary branching involved in mammary gland duct morphogenesis / ovulation from ovarian follicle / negative regulation of phosphorylation / paracrine signaling / maintenance of protein location in nucleus / regulation of epithelial cell proliferation / nuclear steroid receptor activity / lung alveolus development / progesterone receptor signaling pathway / estrogen response element binding / nuclear receptor-mediated steroid hormone signaling pathway / Nuclear signaling by ERBB4 / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / steroid binding / SUMOylation of intracellular receptors / G protein-coupled receptor activity / Nuclear Receptor transcription pathway / transcription coactivator binding / nuclear receptor activity / cell-cell signaling / ATPase binding / DNA-binding transcription activator activity, RNA polymerase II-specific / Estrogen-dependent gene expression / mitochondrial outer membrane / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of gene expression / signaling receptor binding / regulation of transcription by RNA polymerase II / positive regulation of gene expression / chromatin / regulation of DNA-templated transcription / enzyme binding / signal transduction / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleoplasm / identical protein binding / plasma membrane / cytosol 類似検索 - 分子機能 Progesterone receptor / Progesterone receptor / : / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. ... Progesterone receptor / Progesterone receptor / : / Retinoid X Receptor / Retinoid X Receptor / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-type / Ligand-binding domain of nuclear hormone receptor / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 2 Å 詳細データ登録者 Zhang, Z. / Olland, A.M. / Zhu, Y. / Cohen, J. / Berrodin, T. / Chippari, S. / Appavu, C. / Li, S. / Wilhem, J. / Chopra, R. ...Zhang, Z. / Olland, A.M. / Zhu, Y. / Cohen, J. / Berrodin, T. / Chippari, S. / Appavu, C. / Li, S. / Wilhem, J. / Chopra, R. / Fensome, A. / Zhang, P. / Wrobel, J. / Unwalla, R.J. / Lyttle, C.R. / Winneker, R.C. 引用ジャーナル : J.Biol.Chem. / 年 : 2005タイトル : Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget著者 : Zhang, Z. / Olland, A.M. / Zhu, Y. / Cohen, J. / Berrodin, T. / Chippari, S. / Appavu, C. / Li, S. / Wilhem, J. / Chopra, R. / Fensome, A. / Zhang, P. / Wrobel, J. / Unwalla, R.J. / Lyttle, C.R. / Winneker, R.C. 履歴 登録 2005年5月30日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2005年7月5日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月30日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2023年8月23日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
すべて表示 表示を減らす Remark 300 BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 2 CHAIN(S) ... BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 2 CHAIN(S). IT IS NOT KNOWN WHETHER THE DIMER IN THE SAYMMETRIC UNIT IS ACTUALLY THE BIOLOGICAL UNIT.