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Structure paper

TitleMolecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget
Journal, issue, pagesJ. Biol. Chem., Vol. 280, Page 28468-28475, Year 2005
Publish dateMay 30, 2005 (structure data deposition date)
AuthorsZhang, Z. / Olland, A.M. / Zhu, Y. / Cohen, J. / Berrodin, T. / Chippari, S. / Appavu, C. / Li, S. / Wilhem, J. / Chopra, R. ...Zhang, Z. / Olland, A.M. / Zhu, Y. / Cohen, J. / Berrodin, T. / Chippari, S. / Appavu, C. / Li, S. / Wilhem, J. / Chopra, R. / Fensome, A. / Zhang, P. / Wrobel, J. / Unwalla, R.J. / Lyttle, C.R. / Winneker, R.C.
External linksJ. Biol. Chem. / PubMed:15937332
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1zuc:
Progesterone receptor ligand binding domain in complex with the nonsteroidal agonist tanaproget
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-T98:
5-(4,4-DIMETHYL-2-THIOXO-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-6-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE / agonist*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / progesterone receptor / nonsteroidal agonist / tanaproget / progesterone / hormone / HORMONE-GROWTH FACTOR COMPLEX

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