登録情報 | データベース: PDB / ID: 1wy9 |
---|
タイトル | Crystal structure of microglia-specific protein, Iba1 |
---|
要素 | Allograft inflammatory factor 1 |
---|
キーワード | METAL BINDING PROTEIN / EF-hand / calucium binding |
---|
機能・相同性 | 機能・相同性情報
positive regulation of muscle hyperplasia / positive regulation of chemokine production => GO:0032722 / cellular response to morphine / negative regulation of smooth muscle cell chemotaxis / positive regulation of smooth muscle cell chemotaxis / parallel actin filament bundle assembly / positive regulation of fibroblast growth factor production / cellular response to hydroperoxide / actin crosslink formation / : ...positive regulation of muscle hyperplasia / positive regulation of chemokine production => GO:0032722 / cellular response to morphine / negative regulation of smooth muscle cell chemotaxis / positive regulation of smooth muscle cell chemotaxis / parallel actin filament bundle assembly / positive regulation of fibroblast growth factor production / cellular response to hydroperoxide / actin crosslink formation / : / ruffle assembly / positive regulation of mononuclear cell migration / positive regulation of chemotaxis / positive regulation of monocyte chemotaxis / positive regulation of G1/S transition of mitotic cell cycle / phagocytosis, engulfment / Rac protein signal transduction / actin filament bundle assembly / phagocytic cup / response to axon injury / positive regulation of T cell migration / response to electrical stimulus / positive regulation of T cell proliferation / response to glucocorticoid / cellular response to hormone stimulus / ruffle / actin filament polymerization / positive regulation of smooth muscle cell proliferation / cerebellum development / negative regulation of smooth muscle cell proliferation / cell projection / actin filament / ruffle membrane / microglial cell activation / cellular response to type II interferon / actin filament binding / positive regulation of interleukin-6 production / positive regulation of nitric oxide biosynthetic process / lamellipodium / cellular response to oxidative stress / perikaryon / positive regulation of cell migration / positive regulation of protein phosphorylation / inflammatory response / negative regulation of gene expression / positive regulation of cell population proliferation / calcium ion binding / negative regulation of apoptotic process / perinuclear region of cytoplasm / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Allograft inflammatory factor 1 / EF-hand / Recoverin; domain 1 / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
---|
生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
---|
手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 2.1 Å |
---|
データ登録者 | Yamada, M. / Imai, Y. / Kohsaka, S. / Kamitori, S. |
---|
引用 | ジャーナル: J.Mol.Biol. / 年: 2006 タイトル: X-ray Structures of the Microglia/Macrophage-specific Protein Iba1 from Human and Mouse Demonstrate Novel Molecular Conformation Change Induced by Calcium binding 著者: Yamada, M. / Ohsawa, K. / Imai, Y. / Kohsaka, S. / Kamitori, S. |
---|
履歴 | 登録 | 2005年2月9日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2006年2月21日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2008年4月30日 | Group: Version format compliance |
---|
改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
---|
改定 1.3 | 2024年3月13日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
|
---|