[English] 日本語
Yorodumi- PDB-1w9n: Isolation and characterization of epilancin 15X, a novel antibiot... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1w9n | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Title | Isolation and characterization of epilancin 15X, a novel antibiotic from a clinical strain of Staphylococcus epidermidis | ||||||||||||
Components | EPILANCIN 15X | ||||||||||||
Keywords | ANTIBIOTIC / TYPE A LANTIBIOTIC / LANTHIONINE / ANTIBACTERIAL / THIOESTER | ||||||||||||
Function / homology | Lantibiotic, type A, Pep5-type / Type A lantibiotic family / killing of cells of another organism / defense response to bacterium / signaling receptor binding / EPILANCIN 15X / Lantibiotic epilancin 15X Function and homology information | ||||||||||||
Biological species | STAPHYLOCOCCUS EPIDERMIDIS (bacteria) | ||||||||||||
Method | SOLUTION NMR / ARIA | ||||||||||||
Authors | Ekkelenkamp, M. / Hanssen, M.G.M. / Hsu, S.-T.D. / de Jong, A. / Milatovic, D. / Verhoef, J. / van Nuland, N.A.J. | ||||||||||||
Citation | Journal: FEBS Lett. / Year: 2005 Title: Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis. Authors: Ekkelenkamp, M.B. / Hanssen, M. / Danny Hsu, S.T. / de Jong, A. / Milatovic, D. / Verhoef, J. / van Nuland, N.A. #1: Journal: Nat.Struct.Mol.Biol. / Year: 2004 Title: The Nisin-Lipid II Complex Reveals a Pyrophosphate Cage that Provides a Blueprint for Novel Antibiotics Authors: Hsu, S.-T.D. / Breukink, E. / Tischenko, E. / Lutters, M.A. / de Kruijff, B. / Kaptein, R. / Bonvin, A.M.J.J. / van Nuland, N.A.J. #2: Journal: Biochemistry / Year: 2002 Title: Mapping the Targeted Membrane Pore Formation Mechanism by Solution NMR: The Nisin Z and Lipid II Interaction in Sds Micelles Authors: Hsu, S.-T.D. / Breukink, E. / de Kruijff, B. / Kaptein, R. / Bonvin, A.M.J.J. / van Nuland, N.A.J. #3: Journal: J.Biol.Chem. / Year: 2003 Title: NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity Authors: Hsu, S.-T.D. / Breukink, E. / Bierbaum, G. / Sahl, H.-G. / De Kruijff, B. / Kaptein, R. / Bonvin, A.M.J.J. / Van Nuland, N.A.J. | ||||||||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 1w9n.cif.gz | 211.7 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb1w9n.ent.gz | 179.7 KB | Display | PDB format |
PDBx/mmJSON format | 1w9n.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1w9n_validation.pdf.gz | 354.7 KB | Display | wwPDB validaton report |
---|---|---|---|---|
Full document | 1w9n_full_validation.pdf.gz | 452.4 KB | Display | |
Data in XML | 1w9n_validation.xml.gz | 14.9 KB | Display | |
Data in CIF | 1w9n_validation.cif.gz | 21.5 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/w9/1w9n ftp://data.pdbj.org/pub/pdb/validation_reports/w9/1w9n | HTTPS FTP |
-Related structure data
Related structure data | |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-Components
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR experiment |
| ||||||||||||||||||||||||||||
NMR details | Text: NONE |
-Sample preparation
Details | Contents: 10%WATER/90%D2O | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Sample conditions |
|
-NMR measurement
NMR spectrometer |
|
---|
-Processing
NMR software |
| ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Method: ARIA / Software ordinal: 1 | ||||||||||||
NMR ensemble | Conformer selection criteria: LEAST TOTAL ENERGY / Conformers calculated total number: 100 / Conformers submitted total number: 20 |