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TitleNMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles. Conformational Changes are a Key to Antimicrobial Activity
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 13110-, Year 2003
Publish dateSep 17, 2002 (structure data deposition date)
AuthorsHsu, S.-T. / Breukink, E. / Bierbaum, G. / Sahl, H.-G. / De Kruijff, B. / Kaptein, R. / Van Nuland, N.A. / Bonvin, A.M.
External linksJ. Biol. Chem. / PubMed:12562773
MethodsNMR (solution)
Structure data

PDB-1mqx:
NMR Solution Structure of Type-B Lantibiotics Mersacidin in MeOH/H2O Mixture
Method: SOLUTION NMR

PDB-1mqy:
NMR solution structure of type-B lantibiotics mersacidin in DPC micelles
Method: SOLUTION NMR

PDB-1mqz:
NMR solution structure of type-B lantibiotics mersacidin bound to lipid II in DPC micelles
Method: SOLUTION NMR

Source
  • bacillus sp. hil-y85/54728 (bacteria)
KeywordsANTIBIOTIC / ANTIMICROBIAL / TYPE B LANTIBIOTIC / LANTHIONINE / BACTERIOCIN / PEPTIDOGLYCAN / METHICILLIN RESISTANCE / THIOESTER / LANTIBIOTICS / PEPTIDOGLYCAN METHICILLIN RESISTANCE

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