- PDB-1ugn: Crystal structure of LIR1.02, one of the alleles of LIR1 -
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Basic information
Entry
Database: PDB / ID: 1ugn
Title
Crystal structure of LIR1.02, one of the alleles of LIR1
Components
Leukocyte immunoglobulin-like receptor 1
Keywords
IMMUNE SYSTEM / immunoglobulin-like folds
Function / homology
Function and homology information
HLA-A specific inhibitory MHC class I receptor activity / positive regulation of gamma-delta T cell activation involved in immune response / MHC class Ib protein complex binding / HLA-B specific inhibitory MHC class I receptor activity / inhibitory MHC class I receptor activity / negative regulation of dendritic cell differentiation / immune response-inhibiting cell surface receptor signaling pathway / Fc receptor mediated inhibitory signaling pathway / MHC class Ib protein binding / MHC class Ib receptor activity ...HLA-A specific inhibitory MHC class I receptor activity / positive regulation of gamma-delta T cell activation involved in immune response / MHC class Ib protein complex binding / HLA-B specific inhibitory MHC class I receptor activity / inhibitory MHC class I receptor activity / negative regulation of dendritic cell differentiation / immune response-inhibiting cell surface receptor signaling pathway / Fc receptor mediated inhibitory signaling pathway / MHC class Ib protein binding / MHC class Ib receptor activity / immune response-regulating signaling pathway / negative regulation of T cell mediated cytotoxicity / MHC class I receptor activity / negative regulation of CD8-positive, alpha-beta T cell activation / negative regulation of transforming growth factor beta production / negative regulation of alpha-beta T cell activation / negative regulation of serotonin secretion / negative regulation of cytokine production involved in immune response / negative regulation of natural killer cell mediated cytotoxicity / dendritic cell differentiation / interleukin-10-mediated signaling pathway / negative regulation of mononuclear cell proliferation / negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / protein phosphatase 1 binding / negative regulation of osteoclast development / negative regulation of interleukin-12 production / negative regulation of endocytosis / negative regulation of interferon-beta production / negative regulation of dendritic cell apoptotic process / positive regulation of macrophage cytokine production / negative regulation of interleukin-10 production / MHC class I protein binding / negative regulation of calcium ion transport / negative regulation of tumor necrosis factor production / negative regulation of type II interferon production / negative regulation of cell cycle / T cell proliferation involved in immune response / negative regulation of T cell proliferation / positive regulation of defense response to virus by host / SH2 domain binding / response to virus / receptor internalization / positive regulation of type II interferon production / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / cellular response to lipopolysaccharide / defense response to virus / adaptive immune response / positive regulation of apoptotic process / external side of plasma membrane / positive regulation of gene expression / signal transduction / protein homodimerization activity / positive regulation of transcription by RNA polymerase II / extracellular region / plasma membrane / cytoplasm Similarity search - Function
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