登録情報 | データベース: PDB / ID: 1t01 |
---|
タイトル | Vinculin complexed with the VBS1 helix from talin |
---|
要素 | - Talin 1
- unnamed protein product
|
---|
キーワード | CELL ADHESION / STRUCTURAL PROTEIN / five helix bundle |
---|
機能・相同性 | 機能・相同性情報
muscle tendon junction / Platelet degranulation / Smooth Muscle Contraction / regulation of protein localization to adherens junction / GRB2:SOS provides linkage to MAPK signaling for Integrins / podosome ring / outer dense plaque of desmosome / inner dense plaque of desmosome / Integrin signaling / Smooth Muscle Contraction ...muscle tendon junction / Platelet degranulation / Smooth Muscle Contraction / regulation of protein localization to adherens junction / GRB2:SOS provides linkage to MAPK signaling for Integrins / podosome ring / outer dense plaque of desmosome / inner dense plaque of desmosome / Integrin signaling / Smooth Muscle Contraction / p130Cas linkage to MAPK signaling for integrins / SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion / MAP2K and MAPK activation / terminal web / epithelial cell-cell adhesion / zonula adherens / LIM domain binding / Platelet degranulation / dystroglycan binding / muscle alpha-actinin binding / MAP2K and MAPK activation / alpha-catenin binding / vinculin binding / fascia adherens / cell-cell contact zone / integrin activation / adherens junction assembly / apical junction assembly / costamere / regulation of establishment of endothelial barrier / cell-substrate junction assembly / axon extension / protein localization to cell surface / lamellipodium assembly / cortical actin cytoskeleton organization / regulation of focal adhesion assembly / phosphatidylserine binding / alpha-actinin binding / brush border / skeletal muscle myofibril / stress fiber / regulation of cell migration / ruffle / phosphatidylinositol binding / Neutrophil degranulation / cell projection / integrin-mediated signaling pathway / morphogenesis of an epithelium / adherens junction / neuromuscular junction / structural constituent of cytoskeleton / sarcolemma / beta-catenin binding / platelet aggregation / ruffle membrane / Z disc / cell-cell adhesion / cell-cell junction / actin filament binding / actin cytoskeleton / integrin binding / scaffold protein binding / mitochondrial inner membrane / cytoskeleton / cell adhesion / cadherin binding / focal adhesion / ubiquitin protein ligase binding / structural molecule activity / cell surface / protein homodimerization activity / protein-containing complex / plasma membrane / cytoplasm類似検索 - 分子機能 Vinculin repeated domain signature. / : / Talin, R4 domain / Vinculin / Alpha-catenin/vinculin-like / Vinculin-binding site-containing domain / Talin, central / Talin, N-terminal F0 domain / Talin, central domain superfamily / Talin-1/2, rod-segment ...Vinculin repeated domain signature. / : / Talin, R4 domain / Vinculin / Alpha-catenin/vinculin-like / Vinculin-binding site-containing domain / Talin, central / Talin, N-terminal F0 domain / Talin, central domain superfamily / Talin-1/2, rod-segment / Vinculin Binding Site / Talin, middle domain / N-terminal or F0 domain of Talin-head FERM / I/LWEQ domain / I/LWEQ domain superfamily / I/LWEQ domain / I/LWEQ domain profile. / I/LWEQ domain / Vinculin, conserved site / Vinculin family talin-binding region signature. / Vinculin/alpha-catenin / Vinculin family / Phosphotyrosine-binding domain / Alpha-catenin/vinculin-like superfamily / FERM domain signature 1. / FERM conserved site / FERM domain signature 2. / FERM central domain / FERM/acyl-CoA-binding protein superfamily / FERM central domain / FERM superfamily, second domain / FERM domain / FERM domain profile. / Band 4.1 domain / Band 4.1 homologues / Four Helix Bundle (Hemerythrin (Met), subunit A) / PH-like domain superfamily / Ubiquitin-like domain superfamily / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
---|
生物種 | ![](img/tx_bird.gif) Gallus gallus (ニワトリ)
![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.06 Å |
---|
データ登録者 | Papagrigoriou, E. / Gingras, A.R. / Barsukov, I.L. / Critchley, D.R. / Emsley, J. |
---|
引用 | ジャーナル: Embo J. / 年: 2004 タイトル: Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle 著者: PAPAGRIGORIOU, E. / GINGRAS, A.R. / BARSUKOV, I.L. / Bate, N. / Fillingham, I.J. / Patel, B. / Frank, R. / Ziegler, W.H. / Roberts, G.C. / Critchley, D.R. / Emsley, J. |
---|
履歴 | 登録 | 2004年4月7日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2004年8月24日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2008年4月30日 | Group: Version format compliance |
---|
改定 1.2 | 2011年7月13日 | Group: Version format compliance |
---|
改定 1.3 | 2024年2月14日 | Group: Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
---|
|
---|