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- PDB-1psn: THE CRYSTAL STRUCTURE OF HUMAN PEPSIN AND ITS COMPLEX WITH PEPSTATIN -
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Open data
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Basic information
Entry | Database: PDB / ID: 1psn | ||||||
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Title | THE CRYSTAL STRUCTURE OF HUMAN PEPSIN AND ITS COMPLEX WITH PEPSTATIN | ||||||
![]() | PEPSIN 3A | ||||||
![]() | HYDROLASE (ACID PROTEINASE) | ||||||
Function / homology | ![]() multivesicular body lumen / pepsin A / Surfactant metabolism / digestion / aspartic-type endopeptidase activity / proteolysis / extracellular exosome Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() | ||||||
![]() | Fujinaga, M. / Chernaia, M.M. / Tarasova, N. / Mosimann, S.C. / James, M.N.G. | ||||||
![]() | ![]() Title: Crystal structure of human pepsin and its complex with pepstatin. Authors: Fujinaga, M. / Chernaia, M.M. / Tarasova, N.I. / Mosimann, S.C. / James, M.N. #1: ![]() Title: Molecular and Crystal Structures of Monoclinic Porcine Pepsin Refined at 1.8 Angstroms Resolution Authors: Sielecki, A.R. / Fedorov, A.A. / Boodhoo, A. / Andreeva, N.S. / James, M.N.G. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 69.5 KB | Display | ![]() |
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PDB format | ![]() | 50.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 408.4 KB | Display | ![]() |
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Full document | ![]() | 408.7 KB | Display | |
Data in XML | ![]() | 14.2 KB | Display | |
Data in CIF | ![]() | 20.1 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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1 |
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Unit cell |
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Atom site foot note | 1: CIS PROLINE - PRO 23 |
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Components
#1: Protein | Mass: 34631.887 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() |
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#2: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 3.33 Å3/Da / Density % sol: 60.5 % | |||||||||||||||||||||||||
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Crystal grow | *PLUS pH: 5 / Method: vapor diffusion, hanging drop | |||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction source | Source: ![]() |
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Detector | Type: SAN DIEGO MULTIWIRE DETECTION SYSTEM / Detector: AREA DETECTOR / Date: May 12, 1994 |
Radiation | Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Num. obs: 33057 / % possible obs: 75 % / Observed criterion σ(I): 0 |
Reflection | *PLUS Highest resolution: 1.78 Å / Num. measured all: 99655 / Rmerge(I) obs: 0.075 |
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Processing
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Refinement | Resolution: 2.2→30 Å / σ(F): 0 Details: RESIDUES WITH ZERO OCCUPANCIES AND NEGATIVE B-FACTORS ARE DISORDERED AND THEIR POSITIONS ARE NOT CONSIDERED TO HAVE BEEN DETERMINED.
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Displacement parameters | Biso mean: 25 Å2 | ||||||||||||
Refinement step | Cycle: LAST / Resolution: 2.2→30 Å
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Refine LS restraints |
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Refine LS restraints | *PLUS
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