登録情報 データベース : PDB / ID : 1oc0 構造の表示 ダウンロードとリンクタイトル plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin 要素PLASMINOGEN ACTIVATOR INHIBITOR-1 VITRONECTIN 詳細キーワード HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / SERINE PROTEASE INHIBITOR-COMPLEX / SERPIN / PROTEINASE INHIBITOR / FIBRINOLYSIS / CELL MIGRATION / PLASMINOGEN ACTIVATION / HEPARIN-BINDING / CELL ADHESION機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
positive regulation of leukotriene production involved in inflammatory response / dentinogenesis / negative regulation of smooth muscle cell-matrix adhesion / smooth muscle cell-matrix adhesion / rough endoplasmic reticulum lumen / negative regulation of smooth muscle cell migration / peptidase inhibitor complex / negative regulation of vascular wound healing / alphav-beta3 integrin-vitronectin complex / negative regulation of wound healing ... positive regulation of leukotriene production involved in inflammatory response / dentinogenesis / negative regulation of smooth muscle cell-matrix adhesion / smooth muscle cell-matrix adhesion / rough endoplasmic reticulum lumen / negative regulation of smooth muscle cell migration / peptidase inhibitor complex / negative regulation of vascular wound healing / alphav-beta3 integrin-vitronectin complex / negative regulation of wound healing / positive regulation of odontoblast differentiation / negative regulation of cell adhesion mediated by integrin / scavenger receptor activity / negative regulation of endopeptidase activity / protein complex involved in cell-matrix adhesion / negative regulation of plasminogen activation / negative regulation of blood coagulation / regulation of signaling receptor activity / extracellular matrix binding / positive regulation of monocyte chemotaxis / positive regulation of vascular endothelial growth factor receptor signaling pathway / Dissolution of Fibrin Clot / positive regulation of cell-substrate adhesion / Molecules associated with elastic fibres / extracellular matrix structural constituent / cell adhesion mediated by integrin / polysaccharide binding / Syndecan interactions / positive regulation of wound healing / positive regulation of smooth muscle cell migration / endodermal cell differentiation / oligodendrocyte differentiation / basement membrane / protein polymerization / replicative senescence / ECM proteoglycans / Integrin cell surface interactions / positive regulation of blood coagulation / negative regulation of fibrinolysis / regulation of cell adhesion / negative regulation of endothelial cell apoptotic process / negative regulation of extrinsic apoptotic signaling pathway via death domain receptors / serine protease inhibitor complex / fibrinolysis / collagen binding / negative regulation of cell migration / extracellular matrix organization / cell-matrix adhesion / BMAL1:CLOCK,NPAS2 activates circadian gene expression / platelet alpha granule lumen / Regulation of Complement cascade / positive regulation of interleukin-8 production / liver regeneration / SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription / serine-type endopeptidase inhibitor activity / positive regulation of receptor-mediated endocytosis / Golgi lumen / positive regulation of inflammatory response / positive regulation of angiogenesis / positive regulation of peptidyl-tyrosine phosphorylation / cell migration / integrin binding / positive regulation of protein binding / Platelet degranulation / heparin binding / cellular response to lipopolysaccharide / angiogenesis / collagen-containing extracellular matrix / defense response to Gram-negative bacterium / protease binding / blood microparticle / cell adhesion / immune response / intracellular membrane-bounded organelle / signaling receptor binding / endoplasmic reticulum / extracellular space / extracellular exosome / extracellular region / identical protein binding / plasma membrane 類似検索 - 分子機能 Somatomedin B domain, chordata / Somatomedin B -like domains / Somatomedin B domain / Somatomedin B-like domain superfamily / Somatomedin B domain / Somatomedin B domain (SMB) signature. / Somatomedin B (SMB) domain profile. / Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 ... Somatomedin B domain, chordata / Somatomedin B -like domains / Somatomedin B domain / Somatomedin B-like domain superfamily / Somatomedin B domain / Somatomedin B domain (SMB) signature. / Somatomedin B (SMB) domain profile. / Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin, conserved site / Serpins signature. / Hemopexin, conserved site / Hemopexin domain signature. / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily / Serpin superfamily, domain 1 / Serpin (serine protease inhibitor) / SERine Proteinase INhibitors / Hemopexin-like domain / Hemopexin-like repeats / Hemopexin-like domain superfamily / Hemopexin / Hemopexin repeat profile. / Hemopexin-like repeats. / Roll / 2-Layer Sandwich / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性 Vitronectin / Plasminogen activator inhibitor 1 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.28 Å 詳細データ登録者 Read, R.J. / Zhou, A. / Huntington, J.A. / Pannu, N.S. / Carrell, R.W. 引用ジャーナル : Nat.Struct.Biol. / 年 : 2003タイトル : How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration著者 : Zhou, A. / Huntington, J.A. / Pannu, N.S. / Carrell, R.W. / Read, R.J. 履歴 登録 2003年2月3日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2003年6月19日 Provider : repository / タイプ : Initial release改定 1.1 2011年5月8日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2023年12月13日 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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