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データを開く
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基本情報
登録情報 | データベース: PDB / ID: 1ikm | ||||||
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タイトル | NMR study of monomeric human interleukin-8 (30 structures) | ||||||
![]() | HUMAN INTERLEUKIN-8 (MONOMERIC) | ||||||
![]() | CYTOKINE (CHEMOTACTIC) | ||||||
機能・相同性 | ![]() regulation of single stranded viral RNA replication via double stranded DNA intermediate / regulation of entry of bacterium into host cell / interleukin-8 receptor binding / negative regulation of cell adhesion molecule production / CXCR chemokine receptor binding / ATF4 activates genes in response to endoplasmic reticulum stress / embryonic digestive tract development / neutrophil activation / induction of positive chemotaxis / chemokine activity ...regulation of single stranded viral RNA replication via double stranded DNA intermediate / regulation of entry of bacterium into host cell / interleukin-8 receptor binding / negative regulation of cell adhesion molecule production / CXCR chemokine receptor binding / ATF4 activates genes in response to endoplasmic reticulum stress / embryonic digestive tract development / neutrophil activation / induction of positive chemotaxis / chemokine activity / positive regulation of neutrophil chemotaxis / Chemokine receptors bind chemokines / negative regulation of G protein-coupled receptor signaling pathway / Interleukin-10 signaling / cellular response to interleukin-1 / cellular response to fibroblast growth factor stimulus / regulation of cell adhesion / neutrophil chemotaxis / response to endoplasmic reticulum stress / Peptide ligand-binding receptors / calcium-mediated signaling / response to molecule of bacterial origin / receptor internalization / antimicrobial humoral immune response mediated by antimicrobial peptide / positive regulation of angiogenesis / chemotaxis / cellular response to tumor necrosis factor / heparin binding / cellular response to lipopolysaccharide / Senescence-Associated Secretory Phenotype (SASP) / G alpha (i) signalling events / Interleukin-4 and Interleukin-13 signaling / angiogenesis / intracellular signal transduction / G protein-coupled receptor signaling pathway / inflammatory response / negative regulation of cell population proliferation / negative regulation of gene expression / positive regulation of gene expression / signal transduction / extracellular space / extracellular region 類似検索 - 分子機能 | ||||||
生物種 | ![]() | ||||||
手法 | 溶液NMR | ||||||
![]() | Rajarathnam, K. / Clark-Lewis, I. / Sykes, B.D. | ||||||
![]() | ![]() タイトル: 1H NMR solution structure of an active monomeric interleukin-8. 著者: Rajarathnam, K. / Clark-Lewis, I. / Sykes, B.D. #1: ![]() タイトル: Neutrophil Activation by Monomeric Interleukin-8 著者: Rajarathnam, K. / Sykes, B.D. / Kay, C.M. / Dewald, B. / Geiser, T. / Baggiolini, M. / Clark-Lewis, I. | ||||||
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構造の表示
構造ビューア | 分子: ![]() ![]() |
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ダウンロードとリンク
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ダウンロード
PDBx/mmCIF形式 | ![]() | 757 KB | 表示 | ![]() |
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PDB形式 | ![]() | 641.9 KB | 表示 | ![]() |
PDBx/mmJSON形式 | ![]() | ツリー表示 | ![]() | |
その他 | ![]() |
-検証レポート
アーカイブディレクトリ | ![]() ![]() | HTTPS FTP |
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-関連構造データ
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リンク
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集合体
登録構造単位 | ![]()
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NMR アンサンブル |
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要素
#1: タンパク質 | 分子量: 8415.832 Da / 分子数: 1 変異: DEL(1-3), THE AMIDE PROTON OF LEU 25 MODIFIED TO N-METHYL 由来タイプ: 組換発現 / 由来: (組換発現) ![]() |
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Has protein modification | Y |
-実験情報
-実験
実験 | 手法: 溶液NMR |
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試料調製
結晶化 | *PLUS 手法: other / 詳細: NMR |
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解析
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NMR software | 名称: ![]() | ||||||||
NMRアンサンブル | 登録したコンフォーマーの数: 30 |