登録情報 | データベース: PDB / ID: 1hre |
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タイトル | SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4 |
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要素 | HEREGULIN ALPHA |
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キーワード | GROWTH FACTOR |
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機能・相同性 | 機能・相同性情報
ERBB3 signaling pathway / positive regulation of peptidyl-tyrosine autophosphorylation / sequestering of metal ion / ERBB4 signaling pathway / ERBB4-ERBB4 signaling pathway / ventricular cardiac muscle cell differentiation / positive regulation of striated muscle cell differentiation / negative regulation of secretion / endocardial cell differentiation / animal organ development ...ERBB3 signaling pathway / positive regulation of peptidyl-tyrosine autophosphorylation / sequestering of metal ion / ERBB4 signaling pathway / ERBB4-ERBB4 signaling pathway / ventricular cardiac muscle cell differentiation / positive regulation of striated muscle cell differentiation / negative regulation of secretion / endocardial cell differentiation / animal organ development / ERBB2-ERBB4 signaling pathway / GRB7 events in ERBB2 signaling / neural crest cell development / ERBB2 Activates PTK6 Signaling / cardiac muscle cell myoblast differentiation / cell communication / protein tyrosine kinase activator activity / transmembrane receptor protein tyrosine kinase activator activity / PI3K events in ERBB4 signaling / cardiac muscle cell differentiation / Signaling by ERBB4 / mammary gland development / chemorepellent activity / ventricular trabecula myocardium morphogenesis / ErbB-3 class receptor binding / ERBB2 Regulates Cell Motility / regulation of postsynaptic neurotransmitter receptor internalization / PI3K events in ERBB2 signaling / activation of transmembrane receptor protein tyrosine kinase activity / ERBB signaling pathway / negative regulation of cardiac muscle cell apoptotic process / ERBB2-ERBB3 signaling pathway / Long-term potentiation / Signaling by ERBB2 / positive regulation of cell adhesion / negative regulation of extrinsic apoptotic signaling pathway in absence of ligand / SHC1 events in ERBB4 signaling / GRB2 events in ERBB2 signaling / SHC1 events in ERBB2 signaling / Nuclear signaling by ERBB4 / positive regulation of cardiac muscle cell proliferation / transcription coregulator activity / cell surface receptor protein tyrosine kinase signaling pathway / activation of protein kinase B activity / Downregulation of ERBB2:ERBB3 signaling / Signaling by ERBB2 TMD/JMD mutants / cytokine activity / Signaling by ERBB2 KD Mutants / Downregulation of ERBB2 signaling / growth factor activity / wound healing / positive regulation of protein-containing complex assembly / receptor tyrosine kinase binding / Constitutive Signaling by Aberrant PI3K in Cancer / integrin binding / PIP3 activates AKT signaling / nervous system development / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / RAF/MAP kinase cascade / positive regulation of cell growth / cell population proliferation / positive regulation of ERK1 and ERK2 cascade / cell differentiation / receptor ligand activity / intracellular signal transduction / apical plasma membrane / signaling receptor binding / negative regulation of DNA-templated transcription / positive regulation of cell population proliferation / glutamatergic synapse / extracellular space / extracellular region / nucleoplasm / membrane / plasma membrane類似検索 - 分子機能 Neuregulin, C-terminal / Neuregulin-1 / Neuregulin / Neuregulin intracellular region / Laminin / Laminin / EGF-like domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Epidermal growth factor-like domain. ...Neuregulin, C-terminal / Neuregulin-1 / Neuregulin / Neuregulin intracellular region / Laminin / Laminin / EGF-like domain / Immunoglobulin I-set / Immunoglobulin I-set domain / Epidermal growth factor-like domain. / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain signature 1. / EGF-like domain / Immunoglobulin subtype 2 / Immunoglobulin C-2 Type / Ribbon / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR |
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データ登録者 | Nagata, K. / Kohda, D. / Hatanaka, H. / Ichikawa, S. / Inagaki, F. |
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引用 | ジャーナル: EMBO J. / 年: 1994 タイトル: Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. 著者: Nagata, K. / Kohda, D. / Hatanaka, H. / Ichikawa, S. / Matsuda, S. / Yamamoto, T. / Suzuki, A. / Inagaki, F. |
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履歴 | 登録 | 1994年7月21日 | 処理サイト: BNL |
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改定 1.0 | 1994年10月15日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月24日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2017年11月29日 | Group: Derived calculations / Other カテゴリ: pdbx_database_status / pdbx_struct_assembly ...pdbx_database_status / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conf / struct_conf_type Item: _pdbx_database_status.process_site |
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