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Yorodumi- PDB-1bge: CRYSTAL STRUCTURE OF CANINE AND BOVINE GRANULOCYTE-COLONY STIMULA... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1bge | ||||||
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Title | CRYSTAL STRUCTURE OF CANINE AND BOVINE GRANULOCYTE-COLONY STIMULATING FACTOR (G-CSF) | ||||||
Components | GRANULOCYTE COLONY-STIMULATING FACTOR | ||||||
Keywords | CYTOKINE | ||||||
Function / homology | Function and homology information granulocyte colony-stimulating factor receptor binding / positive regulation of myeloid cell differentiation / cytokine activity / growth factor activity / immune response / positive regulation of cell population proliferation / extracellular space Similarity search - Function | ||||||
Biological species | Canis lupus familiaris (dog) | ||||||
Method | X-RAY DIFFRACTION / Resolution: 2.2 Å | ||||||
Authors | Lovejoy, B. / Cascio, D. / Eisenberg, D. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1993 Title: Crystal structure of canine and bovine granulocyte-colony stimulating factor (G-CSF). Authors: Lovejoy, B. / Cascio, D. / Eisenberg, D. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1bge.cif.gz | 86.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1bge.ent.gz | 67.2 KB | Display | PDB format |
PDBx/mmJSON format | 1bge.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1bge_validation.pdf.gz | 423.1 KB | Display | wwPDB validaton report |
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Full document | 1bge_full_validation.pdf.gz | 427.1 KB | Display | |
Data in XML | 1bge_validation.xml.gz | 14.4 KB | Display | |
Data in CIF | 1bge_validation.cif.gz | 20 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/bg/1bge ftp://data.pdbj.org/pub/pdb/validation_reports/bg/1bge | HTTPS FTP |
-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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2 |
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Unit cell |
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-Components
#1: Protein | Mass: 18871.883 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Canis lupus familiaris (dog) / Species: Canis lupus / Strain: familiaris / References: UniProt: P35834 #2: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.25 Å3/Da / Density % sol: 45.38 % | ||||||||||||||||||||||||||||||||||||||||||||||||
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Crystal grow | *PLUS pH: 6.54 / Method: vapor diffusion, hanging drop | ||||||||||||||||||||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
Reflection | *PLUS Highest resolution: 2.2 Å / Num. all: 28860 / Num. obs: 15536 / % possible obs: 90.2 % / Rmerge(I) obs: 0.046 |
-Processing
Software |
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Refinement | Resolution: 2.2→7 Å / σ(F): 1 /
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Refinement step | Cycle: LAST / Resolution: 2.2→7 Å
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Refine LS restraints |
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Software | *PLUS Name: X-PLOR / Classification: refinement | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Rfactor obs: 0.193 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS Type: x_angle_d / Dev ideal: 2.5 |