EMDB-8859: The complete structure of the small subunit processome

Basic information

• Entry: Database: EMDB / ID: EMD-8859
• Title: The complete structure of the small subunit processome
• Map data: small subunit processome, overall map 1

Sample

• Complex: Small subunit processome
  • RNA: x 3 types
  • Protein or peptide: x 63 types
• Ligand: x 1 types

• Keywords: Ribosome assembly / RIBOSOME

Function / homology

Function:

rRNA acetylation involved in maturation of SSU-rRNA / rRNA cytidine N-acetyltransferase activity / mRNA modification / Noc4p-Nop14p complex / tRNA acetylation / box H/ACA snoRNA binding / regulation of ribosomal protein gene transcription by RNA polymerase II / rRNA small subunit pseudouridine methyltransferase Nep1 / t-UTP complex / RNA fragment catabolic process / CURI complex / UTP-C complex / rRNA 2'-O-methylation / Pwp2p-containing subcomplex of 90S preribosome / endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / box C/D sno(s)RNA binding / histone H2AQ104 methyltransferase activity / nuclear microtubule / Mpp10 complex / snoRNA guided rRNA 2'-O-methylation / rRNA (pseudouridine) methyltransferase activity / regulation of rRNA processing / endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rRNA modification / septum digestion after cytokinesis / snRNA binding / positive regulation of RNA binding / SUMOylation of RNA binding proteins / box C/D sno(s)RNA 3'-end processing / tRNA export from nucleus / regulation of transcription by RNA polymerase I / endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rDNA heterochromatin / rRNA methyltransferase activity / positive regulation of rRNA processing / box C/D methylation guide snoRNP complex / U4/U6 snRNP / rRNA base methylation / single-stranded telomeric DNA binding / rRNA primary transcript binding / 90S preribosome assembly / small nuclear ribonucleoprotein complex / sno(s)RNA-containing ribonucleoprotein complex / U4 snRNA binding / protein localization to nucleolus / O-methyltransferase activity / U4 snRNP / mTORC1-mediated signalling / rRNA methylation / poly(U) RNA binding / U3 snoRNA binding / : / poly(A)+ mRNA export from nucleus / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / precatalytic spliceosome / Ribosomal scanning and start codon recognition / preribosome, small subunit precursor / snoRNA binding / spliceosomal complex assembly / establishment of cell polarity / positive regulation of transcription by RNA polymerase I / Major pathway of rRNA processing in the nucleolus and cytosol / SRP-dependent cotranslational protein targeting to membrane / 90S preribosome / GTP hydrolysis and joining of the 60S ribosomal subunit / Formation of a pool of free 40S subunits / nucleolar large rRNA transcription by RNA polymerase I / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / L13a-mediated translational silencing of Ceruloplasmin expression / enzyme activator activity / proteasome assembly / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / RNA processing / maturation of SSU-rRNA / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / U4/U6 x U5 tri-snRNP complex / Transferases; Acyltransferases; Transferring groups other than aminoacyl groups / RNA endonuclease activity / Transferases; Transferring one-carbon groups; Methyltransferases / nuclear periphery / small-subunit processome / spliceosomal complex / ribosomal small subunit biogenesis / small ribosomal subunit rRNA binding / mRNA splicing, via spliceosome / ribosomal small subunit assembly / rRNA processing / cytosolic small ribosomal subunit / unfolded protein binding / ribosome biogenesis / small ribosomal subunit / cytosolic large ribosomal subunit / cytoplasmic translation / tRNA binding / rRNA binding

Domain/homology:

Regulator of rDNA transcription 14 / Regular of rDNA transcription protein 14 / NUC153 / Nucleolar protein 10/Enp2 / : / : / NUC153 domain / U3 small nucleolar RNA-associated protein 8 / Utp8 family / rRNA biogenesis protein Rrp5 / Possible tRNA binding domain / RNA cytidine acetyltransferase NAT10 / Possible tRNA binding domain / Helicase domain / tRNA(Met) cytidine acetyltransferase TmcA, N-terminal / TmcA/NAT10/Kre33 / Helicase / tRNA(Met) cytidine acetyltransferase TmcA, N-terminal / GNAT acetyltransferase 2 / Ribosomal RNA assembly KRR1 / U3 snoRNA associated / Nucleolar complex protein 4 / U3 snoRNA associated / Nucleolar protein 14 / Nop14-like family / U3 small nucleolar RNA-associated protein 6 / rRNA-processing protein Fcf1, PIN domain / U3 small nucleolar RNA-associated protein 6 / NOL6/Upt22 / Small-subunit processome, Utp11 / Sof1-like protein / BING4, C-terminal domain / Fcf2 pre-rRNA processing, C-terminal / Nrap protein domain 1 / Nrap protein, domain 2 / Nrap protein, domain 3 / Nrap protein, domain 4 / Nrap protein, domain 5 / Nrap protein, domain 6 / Ribosomal RNA-processing protein Rrp9-like / Fcf2/DNTTIP2 / WD repeat-containing protein WDR46/Utp7 / Nrap protein domain 1 / Utp11 protein / Sof1-like domain / BING4CT (NUC141) domain / Fcf2 pre-rRNA processing / Nrap protein PAP/OAS-like domain / Nrap protein domain 3 / Nrap protein nucleotidyltransferase domain 4 / Nrap protein PAP/OAS1-like domain 5 / Nrap protein domain 6 / BING4CT (NUC141) domain / rRNA-processing protein Fcf1/Utp23 / Ribosomal RNA-processing protein 7, C-terminal domain / Ribosomal RNA-processing protein 7 / Rrp7, RRM-like N-terminal domain / Fcf1 / Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain / Rrp7 RRM-like N-terminal domain / Small-subunit processome, Utp14 / U3 small nucleolar RNA-associated protein 15, C-terminal / Utp14 protein / UTP15 C terminal / Sas10 C-terminal domain / Sas10 C-terminal domain / Nucleolar protein 58/56, N-terminal / U3 small nucleolar RNA-associated protein 18 / NOP5NT (NUC127) domain / BP28, C-terminal domain / RNA 3'-terminal phosphate cyclase-like, conserved site / U3 small nucleolar RNA-associated protein 10, N-terminal / Ribosome biogenesis protein Bms1, N-terminal / U3 small nucleolar RNA-associated protein 10 / BP28CT (NUC211) domain / U3 small nucleolar RNA-associated protein 10 / RNA 3'-terminal phosphate cyclase signature. / BP28CT (NUC211) domain / U3 small nucleolar RNA-associated protein 13, C-terminal / Periodic tryptophan protein 2 / Utp13 specific WD40 associated domain / Small-subunit processome, Utp12 / Dip2/Utp12 Family / Sas10/Utp3/C1D / Small-subunit processome, Utp21 / U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 / RNA 3'-terminal phosphate cyclase type 2 / Sas10/Utp3/C1D family / Mpp10 protein / Utp21 specific WD40 associated putative domain / Ribosomal biogenesis, methyltransferase, EMG1/NEP1 / EMG1/NEP1 methyltransferase / RNA 3'-terminal phosphate cyclase / RNA 3'-terminal phosphate cyclase, insert domain / RNA 3'-terminal phosphate cyclase domain / RNA 3'-terminal phosphate cyclase, insert domain superfamily / RNA 3'-terminal phosphate cyclase domain superfamily / RNA 3'-terminal phosphate cyclase / RNA 3'-terminal phosphate cyclase (RTC), insert domain / Nucleolar protein Nop56/Nop58

Component:

RPS5 isoform 1 / KRR1 small subunit processome component / Regulator of rDNA transcription 14 / U3 small nucleolar RNA-associated protein 11 / Regulator of rDNA transcription 14 / Small ribosomal subunit protein uS4A / Small ribosomal subunit protein uS15 / Small ribosomal subunit protein uS11A / Small ribosomal subunit protein uS8A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Small ribosomal subunit protein uS17A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Small ribosomal subunit protein uS12A / rRNA 2'-O-methyltransferase fibrillarin / Ribosomal RNA-processing protein 7 / Periodic tryptophan protein 2 / Small ribosomal subunit protein eS7A / U3 small nucleolar ribonucleoprotein protein IMP3 / Protein SOF1 / Ribosome biogenesis protein UTP30 / Essential nuclear protein 1 / U3 small nucleolar RNA-associated protein 9 / 13 kDa ribonucleoprotein-associated protein / U3 small nucleolar RNA-associated protein 7 / U3 small nucleolar ribonucleoprotein protein LCP5 / U3 small nucleolar RNA-associated protein 18 / Protein FAF1 / U3 small nucleolar RNA-associated protein 10 / U3 small nucleolar RNA-associated protein MPP10 / Ribosome biogenesis protein ENP2 / U3 small nucleolar RNA-associated protein 22 / U3 small nucleolar RNA-associated protein 8 / RNA cytidine acetyltransferase / U3 small nucleolar ribonucleoprotein protein IMP4 / U3 small nucleolar RNA-associated protein 6 / NET1-associated nuclear protein 1 / U3 small nucleolar RNA-associated protein 5 / U3 small nucleolar RNA-associated protein 15 / U3 small nucleolar RNA-associated protein 14 / rRNA biogenesis protein RRP5 / rRNA-processing protein FCF1 / U3 small nucleolar RNA-associated protein 13 / U3 small nucleolar RNA-associated protein 21 / Ribosomal RNA small subunit methyltransferase NEP1 / Ribosomal RNA-processing protein 9 / Nucleolar complex protein 4 / U3 small nucleolar RNA-associated protein 4 / RNA 3'-terminal phosphate cyclase-like protein / Bud site selection protein 21 / Ribosome biogenesis protein BMS1 / rRNA-processing protein FCF2 / Something about silencing protein 10 / U3 small nucleolar RNA-associated protein 12 / Nucleolar protein 56 / Nucleolar protein 58 / Small ribosomal subunit protein eS28A / Nucleolar complex protein 14 / Pre-rRNA-processing protein PNO1

• Biological species: Saccharomyces cerevisiae BY4741 (yeast)
• Method: single particle reconstruction / cryo EM / Resolution: 3.8 Å
• Authors: Barandun J / Chaker-Margot M

Funding support

United States, European Union, Switzerland, Canada, France, 5 items

Organization	Grant number	Country
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)	1DP2GM123459	United States
European Molecular Biology Organization (EMBO)	ALTF 51-2014	European Union
Swiss National Science Foundation	155515	Switzerland
Natural Sciences and Engineering Research Council (NSERC, Canada)	PGS-D	Canada
Human Frontier Science Program (HFSP)		France

• Citation: Journal: Nat Struct Mol Biol / Year: 2017; Title: The complete structure of the small-subunit processome.; Authors: Jonas Barandun / Malik Chaker-Margot / Mirjam Hunziker / Kelly R Molloy / Brian T Chait / Sebastian Klinge / ; Abstract: The small-subunit processome represents the earliest stable precursor of the eukaryotic small ribosomal subunit. Here we present the cryo-EM structure of the Saccharomyces cerevisiae small-subunit processome at an overall resolution of 3.8 Å, which provides an essentially complete near-atomic model of this assembly. In this nucleolar superstructure, 51 ribosome-assembly factors and two RNAs encapsulate the 18S rRNA precursor and 15 ribosomal proteins in a state that precedes pre-rRNA cleavage at site A1. Extended flexible proteins are employed to connect distant sites in this particle. Molecular mimicry and steric hindrance, as well as protein- and RNA-mediated RNA remodeling, are used in a concerted fashion to prevent the premature formation of the central pseudoknot and its surrounding elements within the small ribosomal subunit.

History

Deposition	Jul 26, 2017	-
Header (metadata) release	Sep 13, 2017	-
Map release	Sep 27, 2017	-
Update	Mar 13, 2024	-
Current status	Mar 13, 2024	Processing site: RCSB / Status: Released

Map

• File: Download / File: emd_8859.map.gz / Format: CCP4 / Size: 244.1 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
• Annotation: small subunit processome, overall map 1
• Voxel size: X=Y=Z: 1.3 Å

Density

Contour Level	By AUTHOR: 0.023 / Movie #1: 0.023
Minimum - Maximum	-0.10548593 - 0.16638078
Average (Standard dev.)	0.00023483255 (±0.005812679)

• Symmetry: Space group: 1

Details

EMDB XML:

Map geometry	Axis order X Y Z Origin 0 0 0 Dimensions 400 400 400 Spacing 400 400 400
Cell	A=B=C: 520.0 Å α=β=γ: 90.0 °

CCP4 map header:

mode	Image stored as Reals
Å/pix. X/Y/Z	1.3	1.3	1.3
M x/y/z	400	400	400
origin x/y/z	0.000	0.000	0.000
length x/y/z	520.000	520.000	520.000
α/β/γ	90.000	90.000	90.000
MAP C/R/S	1	2	3
start NC/NR/NS	0	0	0
NC/NR/NS	400	400	400
D min/max/mean	-0.105	0.166	0.000

Supplemental data

Additional map: small subunit processome, central domain map

• File: emd_8859_additional_1.map
• Annotation: small subunit processome, central domain map

Additional map: small subunit processome, core map

• File: emd_8859_additional_2.map
• Annotation: small subunit processome, core map

Additional map: small subunit processome, overall map 2

• File: emd_8859_additional_3.map
• Annotation: small subunit processome, overall map 2

Additional map: small subunit processome, 3' domain map

• File: emd_8859_additional_4.map
• Annotation: small subunit processome, 3' domain map

Sample components

Entire : Small subunit processome

• Entire: Name: Small subunit processome

Components

• Complex: Small subunit processome
  • RNA: 5' ETS
  • RNA: 18S pre-rRNA
  • RNA: U3 snoRNA
  • Protein or peptide: rpS18_uS13
  • Protein or peptide: rpS4_eS4
  • Protein or peptide: rpS5_uS7
  • Protein or peptide: rpS6_eS6
  • Protein or peptide: rpS7_eS7
  • Protein or peptide: rpS8_eS8
  • Protein or peptide: rpS9_uS4
  • Protein or peptide: rpS16_uS9
  • Protein or peptide: rpS11_uS17
  • Protein or peptide: rpS22_uS8
  • Protein or peptide: rpS24_eS24
  • Protein or peptide: rpS28_eS28
  • Protein or peptide: Utp17
  • Protein or peptide: Utp8
  • Protein or peptide: Utp15
  • Protein or peptide: Utp9
  • Protein or peptide: Utp5
  • Protein or peptide: Utp10
  • Protein or peptide: Utp4
  • Protein or peptide: Utp1
  • Protein or peptide: Utp6
  • Protein or peptide: Utp12
  • Protein or peptide: Utp13
  • Protein or peptide: Utp18
  • Protein or peptide: Utp21
  • Protein or peptide: Sof1
  • Protein or peptide: Enp2
  • Protein or peptide: Utp7
  • Protein or peptide: Kre33
  • Protein or peptide: Imp3
  • Protein or peptide: Mpp10
  • Protein or peptide: Sas10SAS (TV station)
  • Protein or peptide: Lcp5
  • Protein or peptide: Bud21
  • Protein or peptide: Faf1
  • Protein or peptide: rpS13_uS15
  • Protein or peptide: rpS14_uS11
  • Protein or peptide: Utp22
  • Protein or peptide: Rrp7
  • Protein or peptide: Rrp5
  • Protein or peptide: Krr1
  • Protein or peptide: Nop56
  • Protein or peptide: Nop58
  • Protein or peptide: Nop1
  • Protein or peptide: Snu13NHP2L1
  • Protein or peptide: Rrp9
  • Protein or peptide: Rcl1
  • Protein or peptide: Bms1
  • Protein or peptide: Emg1
  • Protein or peptide: Utp24
  • Protein or peptide: Imp4
  • Protein or peptide: Utp30
  • Protein or peptide: Pno1
  • Protein or peptide: Utp20
  • Protein or peptide: Fcf2
  • Protein or peptide: rpS23_uS12
  • Protein or peptide: Utp14
  • Protein or peptide: Nop14
  • Protein or peptide: Noc4
  • Protein or peptide: Rrt14
  • Protein or peptide: Unassigned peptides
  • Protein or peptide: Utp11
  • Protein or peptide: Enp1
• Ligand: ZINC ION

Supramolecule #1: Small subunit processome

• Supramolecule: Name: Small subunit processome / type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#66
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast)

Macromolecule #1: 5' ETS

• Macromolecule: Name: 5' ETS / type: rna / ID: 1 / Number of copies: 1
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 225.543094 KDa

Sequence

String:

AUGCGAAAGC AGUUGAAGAC AAGUUCGAAA AGAGUUUGGA AACGAAUUCG AGUAGGCUUG UCGUUCGUUA UGUUUUUGUA AAUGGCCUC GUCAAACGGU GGAGAGAGUC GCUAGGUGAU CGUCAGAUCU GCCUAGUCUC UAUACAGCGU GUUUAAUUGA C AUGGGUUG AUGCGUAUUG AGAGAUACAA UUUGGGAAGA AAUUCCCAGA GUGUGUUUCU UUUGCGUUUA ACCUGAACAG UC UCAUCGU GGGCAUCUUG CGAUUCCAUU GGUGAGCAGC GAAGGAUUUG GUGGAUUACU AGCUAAUAGC AAUCUAUUUC AAA GAAUUC AAACUUGGGG GAAUGCCUUG UUGAAUAGCC GGUCGCAAGA CUGUGAUUCU UCAAGUGUAA CCUCCUCUCA AAUC AGCGA UAUCAAACGU ACCAUUCCGU GAAACACCGG GGUAUCUGUU UGGUGGAACC UGAUUAGAGG AAACUCAAAG AGUGC UAUG GUAUGGUGAC GGAGUGCGCU GGUCAAGAGU GUAAAAGCUU UUUGAACAGA GAGCAUUUCC GGCAGCAGAG AGACCU GAA AAAGCAAUUU UUCUGGAAUU UCAGCUGUUU CCAAACUCAA UAAGUAUCUU CUAGCAAGAG GGAAUAGGUG GGAAAAA AA AAAAGAGAUU UCGGUUUCUU UCUUUUUUAC UGCUUGUUGC UUCUUCUUUU AAGAUAGU

GENBANK: GENBANK: U53879.1

Macromolecule #2: 18S pre-rRNA

• Macromolecule: Name: 18S pre-rRNA / type: rna / ID: 2 / Number of copies: 1
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 582.052438 KDa

Sequence

String:

AGAUAGUUAU CUGGUUGAUC CUGCCAGUAG UCAUAUGCUU GUCUCAAAGA UUAAGCCAUG CAUGUCUAAG UAUAAGCAAU UUAUACAGU GAAACUGCGA AUGGCUCAUU AAAUCAGUUA UCGUUUAUUU GAUAGUUCCU UUACUACAUG GUAUAACUGU G GUAAUUCU AGAGCUAAUA CAUGCUUAAA AUCUCGACCC UUUGGAAGAG AUGUAUUUAU UAGAUAAAAA AUCAAUGUCU UC GGACUCU UUGAUGAUUC AUAAUAACUU UUCGAAUCGC AUGGCCUUGU GCUGGCGAUG GUUCAUUCAA AUUUCUGCCC UAU CAACUU UCGAUGGUAG GAUAGUGGCC UACCAUGGUU UCAACGGGUA ACGGGGAAUA AGGGUUCGAU UCCGGAGAGG GAGC CUGAG AAACGGCUAC CACAUCCAAG GAAGGCAGCA GGCGCGCAAA UUACCCAAUC CUAAUUCAGG GAGGUAGUGA CAAUA AAUA ACGAUACAGG GCCCAUUCGG GUCUUGUAAU UGGAAUGAGU ACAAUGUAAA UACCUUAACG AGGAACAAUU GGAGGG CAA GUCUGGUGCC AGCAGCCGCG GUAAUUCCAG CUCCAAUAGC GUAUAUUAAA GUUGUUGCAG UUAAAAAGCU CGUAGUU GA ACUUUGGGCC CGGUUGGCCG GUCCGAUUUU UUCGUGUACU GGAUUUCCAA CGGGGCCUUU CCUUCUGGCU AACCUUGA G UCCUUGUGGC UCUUGGCGAA CCAGGACUUU UACUUUGAAA AAAUUAGAGU GUUCAAAGCA GGCGUAUUGC UCGAAUAUA UUAGCAUGGA AUAAUAGAAU AGGACGUUUG GUUCUAUUUU GUUGGUUUCU AGGACCAUCG UAAUGAUUAA UAGGGACGGU CGGGGGCAU CAGUAUUCAA UUGUCAGAGG UGAAAUUCUU GGAUUUAUUG AAGACUAACU ACUGCGAAAG CAUUUGCCAA G GACGUUUU CAUUAAUCAA GAACGAAAGU UAGGGGAUCG AAGAUGAUCA GAUACCGUCG UAGUCUUAAC CAUAAACUAU GC CGACUAG GGAUCGGGUG GUGUUUUUUU AAUGACCCAC UCGGCACCUU ACGAGAAAUC AAAGUCUUUG GGUUCUGGGG GGA GUAUGG UCGCAAGGCU GAAACUUAAA GGAAUUGACG GAAGGGCACC ACCAGGAGUG GAGCCUGCGG CUUAAUUUGA CUCA ACACG GGGAAACUCA CCAGGUCCAG ACACAAUAAG GAUUGACAGA UUGAGAGCUC UUUCUUGAUU UUGUGGGUGG UGGUG CAUG GCCGUUCUUA GUUGGUGGAG UGAUUUGUCU GCUUAAUUGC GAUAACGAAC GAGACCUUAA CCUACUAAAU AGUGGU GCU AGCAUUUGCU GGUUAUCCAC UUCUUAGAGG GACUAUCGGU UUCAAGCCGA UGGAAGUUUG AGGCAAUAAC AGGUCUG UG AUGCCCUUAG ACGUUCUGGG CCGCACGCGC GCUACACUGA CGGAGCCAGC GAGUCUAACC UUGGCCGAGA GGUCUUGG U AAUCUUGUGA AACUCCGUCG UGCUGGGGAU AGAGCAUUGU AAUUAUUGCU CUUCAACGAG GAAUUCCUAG UAAGCGCAA GUCAUCAGCU UGCGUUGAUU ACGUCCCUGC CCUUUGUACA CACCGCCCGU CGCUAGUACC GAUUGAAUGG CUUAGUGAGG CCUCAGGAU CUGCUUAGAG AAGGGGGCAA CUCCAUCUCA GAGCGGAGAA UUUGGACAAA CUUGGUCAUU UAGAGGAACU A AAAGUCGU AACAAGGUUU CCGUAGGUGA ACCUGCGGAA GGAUCAUUA

GENBANK: GENBANK: CP011558.1

Macromolecule #3: U3 snoRNA

• Macromolecule: Name: U3 snoRNA / type: rna / ID: 3 / Number of copies: 1
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 106.503258 KDa

Sequence

String:

GUCGACGUAC UUCAUAGGAU CAUUUCUAUA GGAAUCGUCA CUCUUUGACU CUUCAAAAGA GCCACUGAAU CCAACUUGGU UGAUGAGUC CCAUAACCUU UGUACCCCAG AGUGAGAAAC CGAAAUUGAA UCUAAAUUAG CUUGGUCCGC AAUCCUUAGC G GUUCGGCC AUCUAUAAUU UUGAAUAAAA AUUUUGCUUU GCCGUUGCAU UUGUAGUUUU UUCCUUUGGA AGUAAUUACA AU AUUUUAU GGCGCGAUGA UCUUGACCCA UCCUAUGUAC UUCUUUUUUG AAGGGAUAGG GCUCUAUGGG UGGGUACAAA UGG CAGUCU GACAAGU

GENBANK: GENBANK: M26649.1

Macromolecule #4: rpS18_uS13

• Macromolecule: Name: rpS18_uS13 / type: protein_or_peptide / ID: 4 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 16.773332 KDa

Sequence

String:

MSLVVQEQGS FQHILRLLNT NVDGNIKIVY ALTTIKGVGR RYSNLVCKKA DVDLHKRAGE LTQEELERIV QIMQNPTHYK IPAWFLNRQ NDITDGKDYH TLANNVESKL RDDLERLKKI R(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) WGLRVRGQHT KTTGRRRA

UniProtKB: Small ribosomal subunit protein uS13A, Small ribosomal subunit protein uS13A

Macromolecule #5: rpS4_eS4

• Macromolecule: Name: rpS4_eS4 / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 29.46933 KDa

Sequence

String:

MARGPKKHLK RLAAPHHWLL DKLSGCYAPR PSAGPHKLRE SLPLIVFLRN RLKYALNGRE VKAILMQRHV KVDGKVRTDT TYPAGFMDV ITLDATNENF RLVYDVKGRF AVHRITDEEA SYKLGKVKKV QLGKKGVPYV VTHDGRTIRY PDPNIKVNDT V KIDLASGK ITDFIKFDAG KLVYVTGGRN LGRIGTIVHK ERHDGGFDLV HIKDSLDNTF VTRLNNVFVI GEQGKPYISL PK GKGIKLS IAEERDRRRA QQGL

UniProtKB: Small ribosomal subunit protein eS4A

Macromolecule #6: rpS5_uS7

• Macromolecule: Name: rpS5_uS7 / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 25.0726 KDa

Sequence

String:

MSDTEAPVEV QEDFEVVEEF TPVVLATPIP EEVQQAQTEI KLFNKWSFEE VEVKDASLVD YVQVRQPIFV AHTAGRYANK RFRKAQCPI IERLTNSLMM NGRNNGKKLK AVRIIKHTLD IINVLTDQNP IQVVVDAITN TGPREDTTRV GGGGAARRQA V DVSPLRRV NQAIALLTIG AREAAFRNIK TIAETLAEEL INAAKGSSTS YAIKKKDELE RVAKSNR

UniProtKB: RPS5 isoform 1

Macromolecule #7: rpS6_eS6

• Macromolecule: Name: rpS6_eS6 / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 27.054486 KDa

Sequence

String:

MKLNISYPVN GSQKTFEIDD EHRIRVFFDK RIGQEVDGEA VGDEFKGYVF KISGGNDKQG FPMKQGVLLP TRIKLLLTKN VSCYRPRRD GERKRKSVRG AIVGPDLAVL ALVIVKKGEQ ELEGLTDTTV PKRLGPKRAN NIRKFFGLSK EDDVRDFVIR R EVTKGEKT YTKAPKIQRL VTPQRLQRKR HQRALKVRNA QAQREAAAEY AQLLAKRLSE RKAEKAEIRK RRASSLKA

UniProtKB: Small ribosomal subunit protein eS6A

Macromolecule #8: rpS7_eS7

• Macromolecule: Name: rpS7_eS7 / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 21.658209 KDa

Sequence

String:

MSAPQAKILS QAPTELELQV AQAFVELENS SPELKAELRP LQFKSIREID VAGGKKALAI FVPVPSLAGF HKVQTKLTRE LEKKFQDRH VIFLAERRIL PKPSRTSRQV QKRPRSRTLT AVHDKILEDL VFPTEIVGKR VRYLVGGNKI QKVLLDSKDV Q QIDYKLES FQAVYNKLTG KQIVFEIPSE TH

UniProtKB: Small ribosomal subunit protein eS7A

Macromolecule #9: rpS8_eS8

• Macromolecule: Name: rpS8_eS8 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 22.537803 KDa

Sequence

String:

MGISRDSRHK RSATGAKRAQ FRKKRKFELG RQPANTKIGA KRIHSVRTRG GNKKYRALRI ETGNFSWASE GISKKTRIAG VVYHPSNNE LVRTNTLTKA AIVQIDATPF RQWFEAHYGQ TLGKKKNVKE EETVAKSKNA ERKWAARAAS AKIESSVESQ F SAGRLYAC ISSRPGQSGR CDGYILEGEE LAFYLRRLTA KK

UniProtKB: Small ribosomal subunit protein eS8A

Macromolecule #10: rpS9_uS4

• Macromolecule: Name: rpS9_uS4 / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 22.487893 KDa

Sequence

String:

MPRAPRTYSK TYSTPKRPYE SSRLDAELKL AGEFGLKNKK EIYRISFQLS KIRRAARDLL TRDEKDPKRL FEGNALIRRL VRVGVLSED KKKLDYVLAL KVEDFLERRL QTQVYKLGLA KSVHHARVLI TQRHIAVGKQ IVNIPSFMVR LDSEKHIDFA P TSPFGGAR PGRVARRNAA RKAEASGEAA DEADEADEE

UniProtKB: Small ribosomal subunit protein uS4A

Macromolecule #11: rpS16_uS9

• Macromolecule: Name: rpS16_uS9 / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 15.87749 KDa

Sequence

String:

MSAVPSVQTF GKKKSATAVA HVKAGKGLIK VNGSPITLVE PEILRFKVYE PLLLVGLDKF SNIDIRVRVT GGGHVSQVYA IRQAIAKGL VAYHQKYVDE QSKNELKKAF TSYDRTLLIA DSRRPEPKKF GGKGARSRFQ KSYR

UniProtKB: Small ribosomal subunit protein uS9A

Macromolecule #12: rpS11_uS17

• Macromolecule: Name: rpS11_uS17 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 17.785934 KDa

Sequence

String:

MSTELTVQSE RAFQKQPHIF NNPKVKTSKR TKRWYKNAGL GFKTPKTAIE GSYIDKKCPF TGLVSIRGKI LTGTVVSTKM HRTIVIRRA YLHYIPKYNR YEKRHKNVPV HVSPAFRVQV GDIVTVGQCR PISKTVRFNV VKVSAAAGKA NKQFAKF

UniProtKB: Small ribosomal subunit protein uS17A

Macromolecule #13: rpS22_uS8

• Macromolecule: Name: rpS22_uS8 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 14.650062 KDa

Sequence

String:

MTRSSVLADA LNAINNAEKT GKRQVLIRPS SKVIIKFLQV MQKHGYIGEF EYIDDHRSGK IVVQLNGRLN KCGVISPRFN VKIGDIEKW TANLLPARQF GYVILTTSAG IMDHEEARRK HVSGKILGFV Y

UniProtKB: Small ribosomal subunit protein uS8A

Macromolecule #14: rpS24_eS24

• Macromolecule: Name: rpS24_eS24 / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 15.362848 KDa

Sequence

String:

MSDAVTIRTR KVISNPLLAR KQFVVDVLHP NRANVSKDEL REKLAEVYKA EKDAVSVFGF RTQFGGGKSV GFGLVYNSVA EAKKFEPTY RLVRYGLAEK VEKASRQQRK QKKNRDKKIF GTGKRLAKKV ARRNAD

UniProtKB: Small ribosomal subunit protein eS24A

Macromolecule #15: rpS28_eS28

• Macromolecule: Name: rpS28_eS28 / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 7.605847 KDa

Sequence

String:

MDNKTPVTLA KVIKVLGRTG SRGGVTQVRV EFLEDTSRTI VRNVKGPVRE NDILVLMESE REARRLR

UniProtKB: Small ribosomal subunit protein eS28A

Macromolecule #16: Utp17

• Macromolecule: Name: Utp17 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 100.960445 KDa

Sequence

String:

MTQSLGIEQY KLSVVSGGKP ALNNLSSVTG NKNIARLSQD QRNYIIPFNN QIKVYSVETR QCVKTLKFAN NSLLSGIFLQ EEENNESIV KILLGDITVP QQEDAHLITV FTNNGHVIVL NYKGKLVESP KHFKISLADE KLANVFHSEG NYRILTTFKD P SQKAHNSL QSYRLYALTF DDAKKQFEVA HQAEWHNVIL SNISSNGKLL AHMCKDVSTK DHEHKSISVV SLFDDSVNLS FP LGSILSS QTQSLSYNTR YVSSMAIDNM GQQLAVGFAS GVISIVSLAD LQIRLLKWHI DSVLSLSFSH DGSYLLSGGW EKV MSLWQL ETNSQQFLPR LNGIIIDCQV LGPQGNYYSL ILQMTENNSN SDYQFLLLNA SDLTSKLSIN GPLPVFNSTI KHIQ QPISA MNTKNSNSIT SLNHSKKKQS RKLIKSRRQD FTTNVEINPI NKNLYFPHIS AVQIFDFYKN EQVNYQYLTS GVNNS MGKV RFELNLQDPI ITDLKFTKDG QWMITYEIEY PPNDLLSSKD LTHILKFWTK NDNETNWNLK TKVINPHGIS VPITKI LPS PRSVNNSQGC LTADNNGGLK FWSFDSHESN WCLKKISLPN FNHFSNSVSL AWSQDGSLIF HGFDDKLQIL DFDTFKK FE SLENTKTVSE FTLDSEIQTV KLINDTNLIV ATRTTLNAIN LLRGQVINSF DLYPFVNGVY KNGHMDRLIT CDERTGNI A LVINQQLTDL DGVPTINYKS RIIIFDSDLS TKLGNFTHHE YISWIGWNYD TDFIFLDIES TLGVVGTTVN TQLSDEVNN EGILDGLVSN TITTSAS(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)RGKKSDTR DKNTNDNDED EEDIALEFIN GEKKDKLVNM NSFTSMFDNI QNVQMDTFFD RVMKVLT

UniProtKB: NET1-associated nuclear protein 1, NET1-associated nuclear protein 1

Macromolecule #17: Utp8

• Macromolecule: Name: Utp8 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 65.572977 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)RLFKQAIV TCPNLPLNEL LEELFSIRNR ELLLDISFRI LQDFTRDSIK QEMKKLSKLD VQ NFIEFIT SGGEDSSPEC FNPSQSTQLF QLLSLVLDSI GLFSLEGALL ENLTLYIDKQ VEIAERNTEL WNLIDTKGFQ HGF ASSTFD NGTSQKRALP TYTMEYLDI

UniProtKB: U3 small nucleolar RNA-associated protein 8

Macromolecule #18: Utp15

• Macromolecule: Name: Utp15 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 57.765289 KDa

Sequence

String:

MSTARPRIIT SKAPLLPQQT TPEQRYWRQY TSAQLVKEHN SVTHISFNPQ HPHDFAVTSS TRVQIFSSRT RQVIKTFSRF KDVVYSASF RSDGKLLCAG DATGLVSVYD SYNPRTILLS INASTHPTHV TKFHTQDNKI LATASDDRVT RLWDISNAYE P QLELTGAT DYVRTLSFIP AAPHLVATGS YDGLIRLYDT RSSGSTPIYS LNHDQPVENV IAVSPTQIVS CGGNNFKVWD LT SNKKLYE RGNFNKAVTC LDYVENFDSP MQSALIASSL DGHVKVFDPL DNFQVKFGWK FSGPVLSCAV SPSTAQGNRH LVA GLSSGL LAIRTKKKEK RSSDKENAPA SFNKNAKSNN FQRMMRGSEY QGDQEHIIHN DKVRSQRRMR AFERNINQFK WSEA LDNAF VPGMAKELTL TVLQELRKRG KVRVALYGRD ESTLEPLLNW CLKGIEDVRS ASIVADWVAV VLELYGNTLE SSPVL QELM IDLKTKVRHE IHKSKEAQRI EGMLQLLTS

UniProtKB: U3 small nucleolar RNA-associated protein 15

Macromolecule #19: Utp9

• Macromolecule: Name: Utp9 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 64.378512 KDa

Sequence

String:

MGSSLDLVAS FSHDSTRFAF QASVAQKNNV DIYPLNETKD YVVNSSLVSH IDYETNDMKV SDVIFFGWCS DLIDTQSSNI KRKLDEDEG TGESSEQRCE NFFVNGFPDG RIVVYSSNGK DIVNIIKNKK EILGADTDES DIWILDSDKV VKKLQYNNSK P LKTFTLVD GKDDEIVHFQ ILHQNGTLLV CIITKQMVYI VDPSKRRPST KYSFEISDAV ACEFSSDGKY LLIANNEELI AY DLKEDSK LIQSWPVQVK TLKTLDDLIM ALTTDGKINN YKIGEADKVC SIVVNEDLEI IDFTPINSKQ QVLISWLNVN EPN FESISL KEIETQGYIT INKNEKNNAD EADQKKLEEK EEEAQPEVQH EKKETETKIN KKVSKSDQVE IANILS(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)DHLSKI FLTISKSITQ NPWNEENLLP LWLKWLLTLK SGELNSIKDK HTKKNCKHLK SALRSSEEIL PVLL GIQGR LEMLRRQAKL REDLAQLSMQ EGEDDEIEVI EHSNVISNPL QDQASPVEKL EPDSIVYANG ESDEFVDASE YKD

UniProtKB: U3 small nucleolar RNA-associated protein 9, U3 small nucleolar RNA-associated protein 9

Macromolecule #20: Utp5

• Macromolecule: Name: Utp5 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 72.079445 KDa

Sequence

String:

MDSPVLQSAY DPSGQYLCYV TVALDKQRVG VQPTQRATSS GVDTVWNENF LYLEDSKLKV TCLKWVNLAS SDTVAIILGM NNGEIWLYS VLANEVTYKF TTGNSYEIKD IDLMGNQLWC IDSSDAFYQF DLLQFKLLQH FRINNCVQLN KLTIVPAGDS V AQLLVASH SISLIDIEEK KVVMTFPGHV SPVSTLQVIT NEFFISGAEG DRFLNVYDIH SGMTKCVLVA ESDIKELSHS GQ ADSIAVT TEDGSLEIFV DPLVSSSTKK RGNKSKKSSK KIQIVSKDGR KVPIYNAFIN KDLLNVSWLQ NATMPYFKNL QWR EIPNEY TVEISLNWNN KNKSADRDLH GKDLASATNY VEGNARVTSG DNFKHVDDAI KSWERELTSL EQEQAKPPQA NELL TETFG DKLESSTVAR ISGKKTNLKG SNLKTATTTG TVTVILSQAL QSNDHSLLET VLNNRDERVI RDTIFRLKPA LAVIL LERL AERIARQTHR QGPLNVWVKW CLIIHGGYLV SIPNLMSTLS SLHSTLKRRS DLLPRLLALD ARLDCTINKF KTLNYE AGD IHSSEPVVEE DEDDVEYNEE LDDAGLIEDG EESYGSEEEE EGDSDNEEEQ KHTSSKQDGR LETEQSDGEE EAGYSDV EM E

UniProtKB: U3 small nucleolar RNA-associated protein 5

Macromolecule #21: Utp10

• Macromolecule: Name: Utp10 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 200.020719 KDa

Sequence

String:

MSSLSDQLAQ VASNNATVAL DRKRRQKLHS ASLIYNSKTA ATQDYDFIFE NASKALEELS QIEPKFAIFS RTLFSESSIS LDRNVQTKE EIKDLDNAIN AYLLLASSKW YLAPTLHATE WLVRRFQIHV KNTEMLLLST LNYYQTPVFK RILSIIKLPP L FNCLSNFV RSEKPPTALT MIKLFNDMDF LKLYTSYLDQ CIKHNATYTN QLLFTTCCFI NVVAFNSNND EKLNQLVPIL LE ISAKLLA SKSKDCQIAA HTILVVFATA LPLKKTIILA AMETILSNLD AKEAKHSALL TICKLFQTLK GQGNVDQLPS KIF KLFDSK FDTVSILTFL DKEDKPVCDK FITSYTRSIA RYDRSKLNII LSLLKKIRLE RYEVRLIITD LIYLSEILED KSQL VELFE YFISINEDLV LKCLKSLGLT G(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)LTT SLFTNADVNT DIVKQLSDPV E TTKKDTAS FQTFLDKHSE LINTTNVSML TETGERYKKV LSLFTEAIGK GYKASSFLTS FFTTLESRIT FLLRVTISPA AP TALKLIS LNNIAKYINS IEKEVNIFTL VPCLICALRD ASIKVRTGVK KILSLIAKRP STKHYFLSDK LYGENVTIPM LNP KDSEAW LSGFLNEYVT ENYDISRILT PKRNEKVFLM FWANQALLIP SPYAKTVLLD NLNKSPTYAS SYSSLFEEFI SHYL ENRSS WEKSCIANKT NFEHFERSLV NLVSPKEKQS FMIDFVLSAL NSDYEQLANI AAERLISIFA SLNNAQKLKI VQNIV DSSS NVESSYDTVG VLQSLPLDSD IFVSILNQNS ISNEMDQTDF SKRRRRRSST SKNAFLKEEV SQLAELHLRK LTIILE ALD KVRNVGSEKL LFTLLSLLSD LETLDQDGGL PVLYAQETLI SCTLNTITYL KEHGCTELTN VRADILVSAI RNSASPQ VQ NKLLLVIGSL ATLSSEVILH SVMPIFTFMG AHSIRQDDEF TTKVVERTIL TVVPALIKNS KGNEKEEMEF LLLSFTTA L QHVPRHRRVK LFSTLIKTLD PVKALGSFLF LIAQQYSSAL VNFKIGEARI LIEFIKALLV DLHVNEELSG LNDLLDIIK LLTSSKSSSE KKKSLESRVL FSNGVLNFSE SEFLTFMNNT FEFINKITEE TDQDYYDVRR NLRLKVYSVL LDETSDKKLI RNIREEFGT LLEGVLFFIN SVELTFSCIT SQENEEASDS ETSLSDHTTE IKEILFKVLG NVLQILPVDE FVNAVLPLLS T STNEDIRY HLTLVIGSKF ELEGSEAIPI VNNVMKVLLD RMPLESKSVV ISQVILNTMT ALVSKYGKKL EGSILTQALT LA TEKVSSD MTEVKISSLA LITNCVQVLG VKSIAFYPKI VPPSIKLFDA SLADSSNPLK EQLQVAILLL FAGLIKRIPS FLM SNILDV LHVIYFSREV DSSIRLSVIS LIIENIDLKE VLKVLFRIWS TEIATSNDTV AVSLFLSTLE STVENIDKKS ATSQ SPIFF KLLLSLFEFR SISSFDNNTI SRIEASVHEI SNSYVLKMND KVFRPLFVIL VRWAFDGEGV TNAGITETER LLAFF KFFN KLQENLRGII TSYFTYLLEP VDMLLKRFIS KDMENVNLRR LVINSLTSSL KFDRDEYWKS TSRFELISVS LVNQLS NIE NSIGKYLVKA IGALASNNSG VDEHNQILNK LIVEHMKASC SSNEKLWAIR AMKLIYSKIG ESWLVLLPQL VPVIAEL LE DDDEEIEREV RTGLVKVVEN VLGEPFDRYL D

UniProtKB: U3 small nucleolar RNA-associated protein 10, U3 small nucleolar RNA-associated protein 10

Macromolecule #22: Utp4

• Macromolecule: Name: Utp4 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 87.3165 KDa

Sequence

String:

MSSSLLSVLK EKSRSLKIRN KPVKMTSQER MIVHRCRFVD FTPATITSLA FSHKSNINKL TPSDLRLAIG RSNGNIEIWN PRNNWFQEM VIEGGKDRSI EGLCWSNVNG ESLRLFSIGG STVVTEWDLA TGLPLRNYDC NSGVIWSISI NDSQDKLSVG C DNGTVVLI DISGGPGVLE HDTILMRQEA RVLTLAWKKD DFVIGGCSDG RIRIWSAQKN DENMGRLLHT MKVDKAKKES TL VWSVIYL PRTDQIASGD STGSIKFWDF QFATLNQSFK AHDADVLCLT TDTDNNYVFS AGVDRKIFQF SQNTNKSQKN NRW VNSSNR LLHGNDIRAI CAYQSKGADF LVSGGVEKTL VINSLTSFSN GNYRKMPTVE PYSKNVLVNK EQRLVVSWSE STVK IWTMG TDSSTEQNYK LVCKLTLKDD QNISTCSLSP DGQVLVVGRP STTKVFHLQP VGNKLKVTKL DNDLLLRTST KLVKF IDNS KIVICSCEDD VFIVDLESEE DEKPQEVELL EVTSTKSSIK VPYINRINHL EVDQNIAVIS RGCGVVDILD LKARIS KPL ARLNNFITAV HINTSRKSVV VITADNKIYE FNMNLNSEAE NEDSESVLTQ WSKNNTDNLP KEWKTLKENC VGIFSDI EN SSRLWFWGAT WISRIDFDVD FPIN(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) TDESNFMNDE EDDEDDDIDM EISENLNVLL NQGNKIKSTD VQRNEESSGH FFFTD KYKP LLFVDLISSN ELAIIERNPL TFHSKQKAFI QPKLVF

UniProtKB: U3 small nucleolar RNA-associated protein 4, U3 small nucleolar RNA-associated protein 4

Macromolecule #23: Utp1

• Macromolecule: Name: Utp1 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 104.097039 KDa

Sequence

String:

MKSDFKFSNL LGTVYRQGNI TFSDDGKQLL SPVGNRVSVF DLINNKSFTF EYEHRKNIAA IDLNKQGTLL ISIDEDGRAI LVNFKARNV LHHFNFKEKC SAVKFSPDGR LFALASGRFL QIWKTPDVNK DRQFAPFVRH RVHAGHFQDI TSLTWSQDSR F ILTTSKDL SAKIWSVDSE EKNLAATTFN GHRDYVMGAF FSHDQEKIYT VSKDGAVFVW EFTKRPSDDD DNESEDDDKQ EE VDISKYS WRITKKHFFY ANQAKVKCVT FHPATRLLAV GFTSGEFRLY DLPDFTLIQQ LSMGQNPVNT VSVNQTGEWL AFG SSKLGQ LLVYEWQSES YILKQQGHFD STNSLAYSPD GSRVVTASED GKIKVWDITS GFCLATFEEH TSSVTAVQFA KRGQ VMFSS SLDGTVRAWD LIRYRNFRTF TGTERIQFNC LAVDPSGEVV CAGSLDNFDI HVWSVQTGQL LDALSGHEGP VSCLS FSQE NSVLASASWD KTIRIWSIFG RSQQVEPIEV YSDVLALSMR PDGKEVAVST LKGQISIFNI EDAKQVGNID CRKDII SGR FNQDRFTAKN SERSKFFTTI HYSFDGMAIV AGGNNNSICL YDVPNEVLLK RFIVSRNMAL NGTLEFLNSK KMTEAGS LD LIDDAGENSD LEDRIDNSLP GSQRGGDLST RKMRPEVRVT SVQFSPTANA FAAASTEGLL IYSTNDTILF DPFDLDVD V TPHSTVEALR EKQFLNALVM AFRLNEEYLI NKVYEAIPIK EIPLVASNIP AIYLPRILKF IGDFAIESQH IEFNLIWIK ALLSASGGYI NEHKYLFSTA MRSIQRFIVR VAKEVVNTTT DNKYTYRFLV STDGSMEDGA ADDDEVLLKD DADEDNEENE ENDVVMESD DEEGWIGFNG KDNKLPLSNE NDSSDEEENE KELP

UniProtKB: Periodic tryptophan protein 2

Macromolecule #24: Utp6

• Macromolecule: Name: Utp6 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 48.437402 KDa

Sequence

String:

MSKTRYYLEQ CIPEMDDLVE KGLFTKNEVS LIMKKRTDFE HRLNSRGSSI NDYIKYINYE SNVNKLRAKR CKRILQVKKT NSLSDWSIQ QRIGFIYQRG TNKFPQDLKF WAMYLNYMKA RGNQTSYKKI HNIYNQLLKL HPTNVDIWIS CAKYEYEVHA N FKSCRNIF QNGLRFNPDV PKLWYEYVKF ELNFITKLIN RRKVMGLINE REQELDMQNE QKNNQAPDEE KSHLQVPSTG DS MKDKLNE LPEADISVLG NAETNPALRG DIALTIFDVC MKTLGKHYIN KHKGYYAISD SKMNIELNKE TLNYLFSESL RYI KLFDEF (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)

UniProtKB: U3 small nucleolar RNA-associated protein 6

Macromolecule #25: Utp12

• Macromolecule: Name: Utp12 / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 105.037648 KDa

Sequence

String:

MVKSYQRFEQ AAAFGVIASN ANCVWIPASS GNSNGSGPGQ LITSALEDVN IWDIKTGDLV SKLSDGLPPG ASDARGAKPA ECTYLEAHK DTDLLAVGYA DGVIKVWDLM SKTVLLNFNG HKAAITLLQF DGTGTRLISG SKDSNIIVWD LVGEVGLYKL R SHKDSITG FWCQGEDWLI STSKDGMIKL WDLKTHQCIE THIAHTGECW GLAVKDDLLI TTGTDSQVKI WKLDIENDKM GG KLTEMGI FEKQSKQRGL KIEFITNSSD KTSFFYIQNA DKTIETFRIR (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)YSSFI LHPFQTIRSL YKIKSASWTT VSSSKLELV LTTSSNTIEY YSIPYEKRDP TSPAPLKTHT IELQGQRTDV RSIDISDDNK LLATASNGSL KIWNIKTHKC I RTFECGYA LTCKFLPGGL LVILGTRNGE LQLFDLASSS LLDTIEDAHD AAIWSLDLTS DGKRLVTGSA DKTVKFWDFK VE NSLVPGT KNKFLPVLKL HHDTTLELTD DILCVRVSPD DRYLAISLLD NTVKVFFLDS MKFYLSLYGH KLPVLSIDIS FDS KMIITS SADKNIKIWG LDFGDCHKSL FAHQDSIMNV KFLPQSHNFF SCSKDAVVKY WDGEKFECIQ KLYAHQSEVW ALAV ATDGG FVVSSSHDHS IRIWEETEDQ VFLEEEKEKE LEEQYEDTLL TSLEEGNGDD AFKADASGEG VEDEASGVHK QTLES LKAG ERLMEALDLG IAEIEGLEAY NRDMKL(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)KP QGNAVLIAVN KTPEQYIMDT LLRIRMSQLE DALMVMPFSY VLKFLKFIDT VMQNKTLLHS HLPLICKNLF FII KFNHKE LVSQKNEELK LQINRVKTEL RSALKSTEDD LGFNVQGLKF VKQQWNLRHN YEFVDEYDQQ EKESNSARKR VFGT VI

UniProtKB: U3 small nucleolar RNA-associated protein 12, U3 small nucleolar RNA-associated protein 12, U3 small nucleolar RNA-associated protein 12

Macromolecule #26: Utp13

• Macromolecule: Name: Utp13 / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 75.035867 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)EQ EIEEEQEKAK LQVEQEQSLQ NYMSKGDWTN AFLLAMTL D HPMRLFNVLK RALGESRSRQ DTEEGKIEVI FNEELDQAIS ILNDEQLILL MKRCRDWNTN AKTHTIAQRT IRCILMHHN IAKLSEIPGM VKIVDAIIPY TQRHFTRVDN LVEQSYILDY ALVEMDKLF

UniProtKB: U3 small nucleolar RNA-associated protein 13

Macromolecule #27: Utp18

• Macromolecule: Name: Utp18 / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 66.49425 KDa

Sequence

String:

MTMATTAMNV SVPPPDEEEQ LLAKFVFGDT TDLQENLAKF NADFIFNEQE MDVEDQEDEG SESDNSEEDE AQNGELDHVN NDQLFFVDD GGNEDSQDKN EDTMDVDDED DSSSDDYSED SEEAAWIDSD DEKIKVPILV TNKTKKLRTS YNESKINGVH Y INRLRSQF EKIYPRPKWV DDESDSELDD EEDDEEEGSN NVINGDINAL TKILSTTYNY KDTLSNSKLL PPKKLDIVRL KD ANASHPS HSAIQSLSFH PSKPLLLTGG YDKTLRIYHI DGKTNHLVTS LHLVGSPIQT CTFYTSLSNQ NQQNIFTAGR RRY MHSWDL SLENLTHSQT AKIEKFSRLY GHESTQRSFE NFKVAHLQNS QTNSVHGIVL LQGNNGWINI LHSTSGLWLM GCKI EGVIT DFCIDYQPIS RGKFRTILIA VNAYGEVWEF DLNKNGHVIR RWKDQGGVGI TKIQVGGGTT TTCPALQISK IKQNR WLAV GSESGFVNLY DRNNAMTSST PTPVAALDQL TTTISNLQFS PDGQILCMAS RAVKDALRLV HLPSCSVFSN WPTSGT PLG KVTSVAFSPS GGLLAVGNEQ GKVRLWKLNH Y

UniProtKB: U3 small nucleolar RNA-associated protein 18

Macromolecule #28: Utp21

• Macromolecule: Name: Utp21 / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 104.927844 KDa

Sequence

String:

MSIDLKKRKV EEDVRSRGKN SKIFSPFRII GNVSNGVPFA TGTLGSTFYI VTCVGKTFQI YDANTLHLLF VSEKETPSSI VALSAHFHY VYAAYENKVG IYKRGIEEHL LELETDANVE HLCIFGDYLC ASTDDNSIFI YKKSDPQDKY PSEFYTKLTV T EIQGGEIV SLQHLATYLN KLTVVTKSNV LLFNVRTGKL VFTSNEFPDQ ITTAEPAPVL DIIALGTVTG EVIMFNMRKG KR IRTIKIP QSRISSLSFR TDGSSHLSVG TSSGDLIFYD LDRRSRIHVL KNIHRESYGG VTQATFLNGQ PIIVTSGGDN SLK EYVFDP SLSQGSGDVV VQPPRYLRSR GGHSQPPSYI AFADSQSHFM LSASKDRSLW SFSLRKDAQS QEMSQRLHKK QDGG RVGGS TIKSKFPEIV ALAIENARIG EWENIITAHK DEKFARTWDM RNKRVGRWTF DTTDDGFVKS VAMSQCGNFG FIGSS NGSI TIYNMQSGIL RKKYKLHKRA VTGISLDGMN RKMVSCGLDG IVGFYDFNKS TLLGKLKLDA PITAMVYHRS SDLFAL ALD DLSIVVIDAV TQRVVRQLWG HSNRITAFDF SPEGRWIVSA SLDSTIRTWD LPTGGCIDGI IVDNVATNVK FSPNGDL LA TTHVTGNGIC IWTNRAQFKT VSTRTIDESE FARMALPSTS VRGNDSMLSG ALESNGGEDL NDIDFNTYTS LEQIDKEL L TLSIGPRSKM NTLLHLDVIR KRSKPKEAPK KSEKLPFFLQ LSGEKVGDEA SVREGIAHET PEEIHRRDQE AQKKLDAEE QMNKFKVTGR LGFESHFTKQ LREGSQSKDY SSLLATLINF SPAAVDLEIR SLNSFEPFDE IVWFIDALTQ GLKSNKNFEL YETFMSLLF KAHGDVIHAN NKNQDIASAL QNWEDVHKKE DRLDDLVKFC MGVAAFVTTA

UniProtKB: U3 small nucleolar RNA-associated protein 21

Macromolecule #29: Sof1

• Macromolecule: Name: Sof1 / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 56.888918 KDa

Sequence

String:

MKIKTIKRSA DDYVPVKSTQ ESQMPRNLNP ELHPFERARE YTKALNATKL ERMFAKPFVG QLGYGHRDGV YAIAKNYGSL NKLATGSAD GVIKYWNMST REEFVSFKAH YGLVTGLCVT QPRFHDKKPD LKSQNFMLSC SDDKTVKLWS INVDDYSNKN S SDNDSVTN EEGLIRTFDG ESAFQGIDSH RENSTFATGG AKIHLWDVNR LKPVSDLSWG ADNITSLKFN QNETDILAST GS DNSIVLY DLRTNSPTQK IVQTMRTNAI CWNPMEAFNF VTANEDHNAY YYDMRNLSRS LNVFKDHVSA VMDVDFSPTG DEI VTGSYD KSIRIYKTNH GHSREIYHTK RMQHVFQVKY SMDSKYIISG SDDGNVRLWR SKAWERSNVK TTREKNKLEY DEKL KERFR HMPEIKRISR HRHVPQVIKK AQEIKNIELS SIKRREANER RTRKDMPYIS ERKKQIVGTV HKYEDSGRDR KRRKE DDKR DTQEK

UniProtKB: Protein SOF1

Macromolecule #30: Enp2

• Macromolecule: Name: Enp2 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 81.864172 KDa

Sequence

String:

MVLKSTSAND VSVYQVSGTN VSRSLPDWIA KKRKRQLKND LEYQNRVELI QDFEFSEASN KIKVSRDGQY CMATGTYKPQ IHVYDFANL SLKFDRHTDA ENVDFTILSD DWTKSVHLQN DRSIQFQNKG GLHYTTRIPK FGRSLVYNKV NCDLYVGASG N ELYRLNLE KGRFLNPFKL DTEGVNHVSI NEVNGLLAAG TETNVVEFWD PRSRSRVSKL YLENNIDNRP FQVTTTSFRN DG LTFACGT SNGYSYIYDL RTSEPSIIKD QGYGFDIKKI IWLDNVGTEN KIVTCDKRIA KIWDRLDGKA YASMEPSVDI NDI EHVPGT GMFFTANESI PMHTYYIPSL GPSPRWCSFL DSITEELEEK PSDTVYSNYR FITRDDVKKL NLTHLVGSRV LRAY MHGFF INTELYDKVS LIANPDAYKD EREREIRRRI EKERESRIRS SGAVQKPKIK VNKTLVDKLS QKRGDKVAGK VLTDD RFKE MFEDEEFQVD EDDYDFKQLN PVKSIKETEE GAAKRIRALT AAEESDEERI AMKDGRGHYD YEDEESDEEE SDDETN QKS NKEELSEKDL RKMEKQKALI ERRKKEKEQS ERFMNEMKAG TSTSTQRDES AHVTFGEQVG ELLEVENGKK SNESILR RN QRGEAELTFI PQRKSKKDGN YKSRRHDNSS DEEGIDENGN KKDNGRSKPR FENRRRASKN AFRGM

UniProtKB: Ribosome biogenesis protein ENP2

Macromolecule #31: Utp7

• Macromolecule: Name: Utp7 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 62.41857 KDa

Sequence

String:

MGHKKNGHRR QIKERENQNK FERSTYTNNA KNNHTQTKDK KLRAGLKKID EQYKKAVSSA AATDYLLPES NGYLEPENEL EKTFKVQQS EIKSSVDVST ANKALDLSLK EFGPYHIKYA KNGTHLLITG RKGHVASMDW RKGQLRAELF LNETCHSATY L QNEQYFAV AQKKYTFIYD HEGTELHRLK QHIEARHLDF LPYHYLLVTA GETGWLKYHD VSTGQLVSEL RTKAGPTMAM AQ NPWNAVM HLGHSNGTVS LWSPSMPEPL VKLLSARGPV NSIAIDRSGY YMATTGADRS MKIWDIRNFK QLHSVESLPT PGT NVSISD TGLLALSRGP HVTLWKDALK LSGDSKPCFG SMGGNPHRNT PYMSHLFAGN KVENLGFVPF EDLLGVGHQT GITN LIVPG AGEANYDALE LNPFETKKQR QEQEVRTLLN KLPADTITLD PNSIGSVDKR SSTIRLNAKD LAQTTMDANN KAKTN SDIP DVKPDVKGKN SGLRSFLRKK TQNVIDERKL RVQKQLDKEK NIRKRNHQIK QGLISEDHKD VIEEALSRFG

UniProtKB: U3 small nucleolar RNA-associated protein 7

Macromolecule #32: Kre33

• Macromolecule: Name: Kre33 / type: protein_or_peptide / ID: 32 / Number of copies: 2 / Enantiomer: LEVO; EC number: Transferases; Acyltransferases; Transferring groups other than aminoacyl groups
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 95.337062 KDa

Sequence

String:

MAKKAIDSRI PSLIRNGVQT KQRSIFVIVG DRARNQLPNL HYLMMSADLK MNKSVLWAYK KKLLGFTSHR KKRENKIKKE IKRGTREVN EMDPFESFIS NQNIRYVYYK ESEKILGNTY GMCILQDFEA LTPNLLARTI ETVEGGGIVV ILLKS(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)VVARFNER FILSLGSNPN CLVVDDELNV L(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)

UniProtKB: RNA cytidine acetyltransferase, RNA cytidine acetyltransferase

Macromolecule #33: Imp3

• Macromolecule: Name: Imp3 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 21.928529 KDa

Sequence

String:

MVRKLKHHEQ KLLKKVDFLE WKQDQGHRDT QVMRTYHIQN REDYHKYNRI CGDIRRLANK LSLLPPTDPF RRKHEQLLLD KLYAMGVLT TKSKISDLEN KVTVSAICRR RLPVIMHRLK MAETIQDAVK FIEQGHVRVG PNLINDPAYL VTRNMEDYVT W VDNSKIKK TLLRYRNQID DFDFS

UniProtKB: U3 small nucleolar ribonucleoprotein protein IMP3

Macromolecule #34: Mpp10

• Macromolecule: Name: Mpp10 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 67.042492 KDa

Sequence

String:

MSELFGVLKS NAGRIILKDP SATSKDVKAY IDSVINTCKN GSITKKAELD EITVDGLDAN QVWWQVKLVL DSIDGDLIQG IQELKDVVT PSHNLSDGST LNSSSGEESE LEEAESVFKE KQMLSADVSE IEEQSNDSLS ENDEEPSMDD EKTSAEAARE E FAEEKRIS SGQDERHSSP DPYGINDKFF DLEKFNRDTL AAEDSNEASE GSEDEDIDYF QDMPSDDEEE EAIYYEDFFD KP TKEPVKK HSDVKDPKED EELDEEEHDS AMDKVKLDLF ADEEDEPNAE GVGEASDKNL SSFEKQQIEI RKQIEQLENE AVA EKKWSL KGEVKAKDRP EDALLTEELE FDRTAKPVPV ITSEVTESLE DMIRRRIQDS NFDDLQRRTL LDITRKSQRP QFEL SDVKS SKSLAEIYED DYTRAEDESA LSEELQKAHS EISELYANLV YKLDVLSSVH FVPKPASTSL EIRVETPTIS MEDAQ PLYM SNASSLAPQE IYNVGKAEKD GEIRLKNGVA MSKEELTRED KNRLRRALKR KRSKANLPNV NKRSKRNDVV DTLSKA KNI TVINQKGEKK DVSGKTKKSR SGPDSTNIKL

UniProtKB: U3 small nucleolar RNA-associated protein MPP10

Macromolecule #35: Sas10

• Macromolecule: Name: Sas10 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 69.705703 KDa

Sequence

String:

MVRKGSNRTK TSEVGDEINP YGLNEVDDFA SKREKVLLGQ STFGDSNKDD DHSLLEDEDE EEVLAMDEDD ESIDEREDEE EEEEEELDG AAAYKKIFGR NLETDQLPEE DEENGMLDNE NAWGSTKGEY YGADDLDDDE AAKEIEKEAL RQQKKHLEEL N MNDYLDEE EEEEWVKSAK EFDMGEFKNS TKQADTKTSI TDILNMDDEA RDNYLRTMFP EFAPLSKEFT ELAPKFDELK KS EENEFNK LKLIALGSYL GTISCYYSIL LHELHNNEDF TSMKGHPVME KILTTKEIWR QASELPSSFD VNEGDGSESE ETA NIEAFN EKKLNELQNS EDSDAEDGGK QKQEIDEEER ESDEEEEEED VDIDDFEEYV AQSRLHSKPK TSSMPEADDF IESE IADVD AQDKKARRRT LRFYTSKIDQ QENKKTDRFK GDDDIP(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) DEARKRGMHD NNGADLDDKD YGSEDEAVSR SINTQGENDY YQQVQRGKQD KKISRKEAH KNAVIAAREG KLAELAENVS GDGKRAINYQ ILKNKGLTPK RNKDNRNSRV KKRKKYQKAQ KKLKSVRAVY S GGQSGVYE GEKTGIKKGL TRSVKFKN

UniProtKB: Something about silencing protein 10, Something about silencing protein 10

Macromolecule #36: Lcp5

• Macromolecule: Name: Lcp5 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 40.864391 KDa

Sequence

String:

MSELNALLKD INGSLTATSE SLERLSGIYS NSATDEIPES NQLHEHLFYD AKKPAEKVSL LSLKNGSMLG YINSLLMLIG NRLDDECKD PSAMDARERS IQHRVVLERG VKPLEKKLAY QLDKLTRAYV KMEKEYKDAE KRALEKSTLV NHSGNDDSED D ESSEDEIA YRPNTSGIIN TNKKSSAYRV EETAKQENGE ENDDNETGVY KPPKITAVLP PQQTHFEDRF DAREHKDRSN KS RMQAMEE YIRESSDQPD WSASIGADIV NHGRGGIKSL RDTEKERRVT SFEEDNFTRL NITNKAEKRK QKQRERNARM NVI GGEDFG IFSSKRKLED STSRRGAKKT RSAWDRAQRR L

UniProtKB: U3 small nucleolar ribonucleoprotein protein LCP5

Macromolecule #37: Bud21

• Macromolecule: Name: Bud21 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 23.835627 KDa

Sequence

String:

MSNGHVKFDA DESQASASAV TDRQDDVLVI SKKDKEVHSS SDEESDDDDA PQEEGLHSGK SEVESQITQR EEAIRLEQSQ LRSKRRKQN ELYAKQKKSV N(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)QKDEGST QYSSSRHVTF DKLDESDENE EALAKAIK T KKRKTLKNLR KDSVKRGKFR VQLLSTTQDS KTLPPKKESS IIRSKDRWLN RKALNKG

UniProtKB: Bud site selection protein 21, Bud site selection protein 21

Macromolecule #38: Faf1

• Macromolecule: Name: Faf1 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 38.173699 KDa

Sequence

String:

MTLDDDDYIK QMELQRKAFE SQFGSLESMG FEDKTKNIRT EVDTRDSSGD EIDNSDHGSD FKDGTIESSN SSDEDSGNET AEENNQDSK PK(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) SGKTLTQINK KLESTEAKE EKEDETLEAE NLQNDLELQQ FLRESHLLSA FNNGGSGSTN SGVSLTLQSM GGGNDDGIVY QDDQVIGKAR S RTLEMRLN RLSRVNGHQD KINKLEKVPM HIRRGMIDKH VKRIKKYEQE AAEGGIVLSK VKKGQFRKIE STYKKDIERR IG GSIKARD KEKATKRERG LKISSVGRST RNGLIVSKRD IARISGGERS GKFNGKKKSR R

UniProtKB: Protein FAF1, Protein FAF1

Macromolecule #39: rpS13_uS15

• Macromolecule: Name: rpS13_uS15 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 17.059945 KDa

Sequence

String:

MGRMHSAGKG ISSSAIPYSR NAPAWFKLSS ESVIEQIVKY ARKGLTPSQI GVLLRDAHGV TQARVITGNK IMRILKSNGL APEIPEDLY YLIKKAVSVR KHLERNRKDK DAKFRLILIE SRIHRLARYY RTVAVLPPNW KYESATASAL VN

UniProtKB: Small ribosomal subunit protein uS15

Macromolecule #40: rpS14_uS11

• Macromolecule: Name: rpS14_uS11 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 14.562655 KDa

Sequence

String:

MSNVVQARDN SQVFGVARIY ASFNDTFVHV TDLSGKETIA RVTGGMKVKA DRDESSPYAA MLAAQDVAAK CKEVGITAVH VKIRATGGT RTKTPGPGGQ AALRALARSG LRIGRIEDVT PVPSDSTRKK GGRRGRRL

UniProtKB: Small ribosomal subunit protein uS11A

Macromolecule #41: Utp22

• Macromolecule: Name: Utp22 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 140.660141 KDa

Sequence

String:

MATSVKRKAS ETSDQNIVKV QKKHSTQDST TDNGSKENDH SSQAINERTV PEQENDESDT SPESNEVATN TAATRHNGKV TATESYDIH IARETAELFK SNIFKLQIDE LLEQVKLKQK HVLKVEKFLH KLYDILQEIP DWEEKSLAEV DSFFKNKIVS V PFVDPKPI PQNTNYKFNY KKPDISLIGS FALKAGIYQP NGSSIDTLLT MPKELFEKKD FLNFRCLHKR SVYLAYLTHH LL ILLKKDK LDSFLQLEYS YFDNDPLLPI LRISCSKPTG DSLSDYNFYK TRFSINLLIG FPYKVFEPKK LLPNRNCIRI AQE SKEQSL PATPLYNFSV LSSSTHENYL KYLYKTKKQT ESFVEATVLG RLWLQQRGFS SNMSHSGSLG GFGTFEFTIL MAAL LNGGG INSNKILLHG FSSYQLFKGV IKYLATMDLC HDGHLQFHSN PENSSSSPAS KYIDEGFQTP TLFDKSTKVN ILTKM TVSS YQILKEYAGE TLRMLNNVVQ DQFSNIFLTN ISRFDNLKYD LCYDVQLPLG KYNNLETSLA ATFGSMERVK FITLEN FLA HKITNVARYA LGDRIKYIQI EMVGQKSDFP ITKRKVYSNT GGNHFNFDFV RVKLIVNPSE CDKLVTKGPA HSETMST EA AVFKNFWGIK SSLRRFKDGS ITHCCVWSTS SSEPIISSIV NFALQKHVSK KAQISNETIK KFHNFLPLPN LPSSAKTS V LNLSSFFNLK KSFDDLYKII FQMKLPLSVK SILPVGSAFR YTSLCQPVPF AYSDPDFFQD VILEFETSPK WPDEITSLE KAKTAFLLKI QEELSANSST YRSFFSRDES IPYNLEIVTL NILTPEGYGF KFRVLTERDE ILYLRAIANA RNELKPELEA TFLKFTAKY LASVRHTRTL ENISHSYQFY SPVVRLFKRW LDTHLLLGHI TDELAELIAI KPFVDPAPYF IPGSLENGFL K VLKFISQW NWKDDPLILD LVKPEDDIRD TFETSIGAGS ELDSKTMKKL SERLTLAQYK GIQMNFTNLR NSDPNGTHLQ FF VASKNDP SGILYSSGIP LPIATRLTAL AKVAVNLLQT HGLNQQTINL LFTPGLKDYD FVVDLRTPIG LKSSCGILSA TEF KNITND QAPSNFPENL NDLSEKMDPT YQLVKYLNLK YKNSLILSSR KYIGVNGGEK GDKNVITGLI KPLFKGAHKF RVNL DCNVK PVDDENVILN KEAIFHEIAA FGNDMVINFE TD

UniProtKB: U3 small nucleolar RNA-associated protein 22

Macromolecule #42: Rrp7

• Macromolecule: Name: Rrp7 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 34.526441 KDa

Sequence

String:

MGIEDISAMK NGFIVVPFKL PDHKALPKSQ EASLHFMFAK RHQSSNSNES DCLFLVNLPL LSNIEHMKKF VGQLCGKYDT VSHVEELLY NDEFGLHEVD LSALTSDLMS STDVNEKRYT PRNTALLKFV DAASINNCWN ALKKYSNLHA KHPNELFEWT Y TTPSFTTF VNFYKPLDID YLKEDIHTHM AIFEQREAQA QEDVQSSIVD EDGFTLVVGK NTKSLNSIRK KILNKNPLSK HE NKAKPIS NIDKKAKKDF YRFQVRERKK QEINQLLSKF KEDQERIKVM KAKRKFNPYT

UniProtKB: Ribosomal RNA-processing protein 7

Macromolecule #43: Rrp5

• Macromolecule: Name: Rrp5 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 193.411422 KDa

Sequence

String:

MVASTKRKRD EDFPLSREDS TKQPSTSSLV RNTEEVSFPR GGASALTPLE LKQVANEAAS DVLFGNESVK ASEPASRPLK KKKTTKKST SKDSEASSAN SDEARAGLIE HVNFKTLKNG SSLLGQISAI TKQDLCITFT DGISGYVNLT HISEEFTSIL E DLDEDMDS DTDAADEKKS KVEDAEYESS DDEDEKLDKS NELPNLRRYF HIGQWLRCSV IKNTSLEPST KKSKKKRIEL TI EPSSVNI YADEDLVKST SIQCAVKSIE DHGATLDVGL PGFTGFIAKK DFGNFEKLLP GAVFLGNITK KSDRSIVVNT DFS DKKNKI TQISSIDAII PGQIVDLLCE SITKNGIAGK VFGLVSGVVN VSHLRTFSEE DLKHKFVIGS SIRCRIIACL ENKS GDKVL ILSNLPHILK LEDALRSTEG LDAFPIGYTF ESCSIKGRDS EYLYLALDDD RLGKVHSSRV GEIENSENLS SRVLG YSPV DDIYQLSTDP KYLKLKYLRT NDIPIGELLP SCEITSVSSS GIELKIFNGQ FKASVPPLHI SDTRLVYPER KFKIGS KVK GRVISVNSRG NVHVTLKKSL VNIEDNELPL VSTYENAKNI KEKNEKTLAT IQVFKPNGCI ISFFGGLSGF LPNSEIS EV FVKRPEEHLR LGQTVIVKLL DVDADRRRII ATCKVSNEQA AQQKDTIENI VPGRTIITVH VIEKTKDSVI VEIPDVGL R GVIYVGHLSD SRIEQNRAQL KKLRIGTELT GLVIDKDTRT RVFNMSLKSS LIKDAKKETL PLTYDDVKDL NKDVPMHAY IKSISDKGLF VAFNGKFIGL VLPSYAVDSR DIDISKAFYI NQSVTVYLLR TDDKNQKFLL SLKAPKVKEE KKKVESNIED PVDSSIKSW DDLSIGSIVK AKIKSVKKNQ LNVILAANLH GRVDIAEVFD TYEEITDKKQ PLSNYKKDDV IKVKIIGNHD V KSHKFLPI THKISKASVL ELSMKPSELK SKEVHTKSLE EINIGQELTG FVNNSSGNHL WLTISPVLKA RISLLDLADN DS NFSENIE SVFPLGSALQ VKVASIDREH GFVNAIGKSH VDINMSTIKV GDELPGRVLK IAEKYVLLDL GNKVTGISFI TDA LNDFSL TLKEAFEDKI NNVIPTTVLS VDEQNKKIEL SLRPATAKTR SIKSHEDLKQ GEIVDGIVKN VNDKGIFVYL SRKV EAFVP VSKLSDSYLK EWKKFYKPMQ YVLGKVVTCD EDSRISLTLR ESEINGDLKV LKTYSDIKAG DVFEGTIKSV TDFGV FVKL DNTVNVTGLA HITEIADKKP EDLSALFGVG DRVKAIVLKT NPEKKQISLS LKASHFSKEA ELASTTTTTT TVDQLE KED EDEVMADAGF NDSDSESDIG DQNTEVADRK PETSSDGLSL SAGFDWTASI LDQAQEEEES DQDQEDFTEN KKHKHKR RK ENVVQDKTID INTRAPESVA DFERLLIGNP NSSVVWMNYM AFQLQLSEIE KARELAERAL KTINFREEAE KLNIWIAM L NLENTFGTEE TLEEVFSRAC QYMDSYTIHT KLLGIYEISE KFDKAAELFK ATAKKFGGEK VSIWVSWGDF LISHNEEQE ARTILGNALK ALPKRNHIEV VRKFAQLEFA KGDPERGRSL FEGLVADAPK RIDLWNVYVD QEVKAKDKKK VEDLFERIIT KKITRKQAK FFFNKWLQFE ESEGDEKTIE YVKAKATEYV ASHESQKADE

UniProtKB: rRNA biogenesis protein RRP5

Macromolecule #44: Krr1

• Macromolecule: Name: Krr1 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 37.226254 KDa

Sequence

String:

MVSTHNRDKP WDTDDIDKWK IEEFKEEDNA SGQPFAEESS FMTLFPKYRE SYLKTIWNDV TRALDKHNIA CVLDLVEGSM TVKTTRKTY DPAIILKARD LIKLLARSVP FPQAVKILQD DMACDVIKIG NFVTNKERFV KRRQRLVGPN GNTLKALELL T KCYILVQG NTVSAMGPFK GLKEVRRVVE DCMKNIHPIY HIKELMIKRE LAKRPELANE DWSRFLPMFK KRNVARKKPK KI RNVEKKV YTPFPPAQLP RKVDLEIESG EYFLSKREKQ MKKLNEQKEK QMEREIERQE ERAKDFIAPE EEAYKPNQN

UniProtKB: KRR1 small subunit processome component

Macromolecule #45: Nop56

• Macromolecule: Name: Nop56 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 56.394863 KDa

Sequence

String:

MAPIEYLLFE EPTGYAVFKV KLQQDDIGSR LKEVQEQIND FGAFTKLIEL VSFAPFKGAA EALENANDIS EGLVSESLKA ILDLNLPKA SSKKKNITLA ISDKNLGPSI KEEFPYVDCI SNELAQDLIR GVRLHGEKLF KGLQSGDLER AQLGLGHAYS R AKVKFSVQ KNDNHIIQAI ALLDQLDKDI NTFAMRVKEW YGWHFPELAK LVPDNYTFAK LVLFIKDKA(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)NAR ISMGQDISET DMENVCVFAQ RVASLADYRR QLYDYLC EK MHTVAPNLSE LIGEVIGARL ISHAGSLTNL SKQAASTVQI LGAEKALFRA LKTKGNTPKY GLIYHSGFIS KASAKNKG R ISRYLANKCS MASRIDNYSE EPSNVFGSVL KKQVEQRLEF YNTGKPTLKN ELAIQEAMEL YNKDKPAAEV EETKEKESS KKRKLEDDDE EKKEKKEKKS KKEKKEKKEK KDKKEKKDKK EKKDKKKKSK D

UniProtKB: Nucleolar protein 56, Nucleolar protein 56, Nucleolar protein 56

Macromolecule #46: Nop58

• Macromolecule: Name: Nop58 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 53.81452 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) DNDLSKMSLG LAHSIGRHKL KFSADKVDVM IIQAIALLDD LDKELNTYAM RCKEWYGWHF PELAKIVTD SVAYARIILT MGIRSKASET DLSEILPEEI EERVKTAAEV SMGTEITQTD LDNINALAEQ IVEFAAYREQ L SNYLSARM KAIAPNLTQL VGELVGARLI AHSGSLISLA KSPASTIQIL GAEKALFRAL KTKHDTPKYG LLYHASLVGQ AT GKNKGKI ARVLAAKAAV SLRYDALAED RDDSGDIGLE SRAKVENRLS QLEGRDLRTT PKVVREAKKV EMTEARAYNA DAD TAKAAS DSESDSDDEE EEKKEKKEKK RKRDDDEDSK DSKKAKKEKK DKKEKKEKKE KKEKKEKKEK KEKKSKKEKK EKK

UniProtKB: Nucleolar protein 58

Macromolecule #47: Nop1

• Macromolecule: Name: Nop1 / type: protein_or_peptide / ID: 47 / Number of copies: 2 / Enantiomer: LEVO; EC number: Transferases; Transferring one-carbon groups; Methyltransferases
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 34.525418 KDa

Sequence

String:

MSFRPGSRGG SRGGSRGGFG GRGGSRGGAR GGSRGGFGGR GGSRGGARGG SRGGFGGRGG SRGGARGGSR GGRGGAAGGA RGGAKVVIE PHRHAGVYIA RGKEDLLVTK NMAPGESVYG EKRISVEEPS KEDGVPPTKV EYRVWNPFRS KLAAGIMGGL D ELFIAPGK KVLYLGAASG TSVSHVSDVV GPEGVVYAVE FSHRPGRELI SMAKKRPNII PIIEDARHPQ KYRMLIGMVD CV FADVAQP DQARIIALNS HMFLKDQGGV VISIKANCID STVDAETVFA REVQKLREER IKPLEQLTLE PYERDHCIVV GRY MRSGLK K

UniProtKB: rRNA 2'-O-methyltransferase fibrillarin

Macromolecule #48: Snu13

• Macromolecule: Name: Snu13 / type: protein_or_peptide / ID: 48 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 13.582855 KDa

Sequence

String:

MSAPNPKAFP LADAALTQQI LDVVQQAANL RQLKKGANEA TKTLNRGISE FIIMAADCEP IEILLHLPLL CEDKNVPYVF VPSRVALGR ACGVSRPVIA ASITTNDASA IKTQIYAVKD KIETLLI

UniProtKB: 13 kDa ribonucleoprotein-associated protein

Macromolecule #49: Rrp9

• Macromolecule: Name: Rrp9 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 65.146969 KDa

Sequence

String:

MSDVTQQKKR KRSKGEVNPS KPTVDEEITD PSSNEDEQLE VSDEEDALES EEEFEGENPA DKRRRLAKQY LENLKSEAND ILTDNRNAE EKDLNNLKER TIDEYNNFDA GDLDKDIIAS RLKEDVAEQQ GRVFRYFGDK LLISEAKQSF TRVGENNLTC I SCFQPVLN KYTFEESSNG DKNKGRLFAY TVSKDLQLTK YDITDFSKRP KKLKYAKGGA KYIPTSKHEY ENTTEGHYDE IL TVAASPD GKYVVTGGRD RKLIVWSTES LSPVKVIPTK DRRGEVLSLA FRKNSDQLYA SCADFKIRTY SINQFSQLEI LYG HHDIVE DISALAMERC VTVGARDRTA MLWKIPDETR LTFRGGDEPQ KLLRRWMKEN AKEGEDGEVK YPDESEAPLF FCEG SIDVV SMVDDFHFIT GSDNGNICLW SLAKKKPIFT ERIAHGILPE PSFNDISGET DEELRKRQLQ GKKLLQPFWI TSLYA IPYS NVFISGSWSG SLKVWKISDN LRSFELLGEL SGAKGVVTKI QVVESGKHGK EKFRILASIA KEHRLGRWIA NVSGAR NGI YSAVIDQTGF

UniProtKB: Ribosomal RNA-processing protein 9

Macromolecule #50: Rcl1

• Macromolecule: Name: Rcl1 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 40.220559 KDa

Sequence

String:

MSSSAPKYTT FQGSQNFRLR IVLATLSGKP IKIEKIRSGD LNPGLKDYEV SFLRLIESVT NGSVIEISYT GTTVIYRPGI IVGGASTHI CPSSKPVGYF VEPMLYLAPF SKKKFSILFK GITASHNDAG IEAIKWGLMP VMEKFGVREC ALHTLKRGSP P LGGGEVHL VVDSLIAQPI TMHEIDRPII SSITGVAYST RVSPSLVNRM IDGAKKVLKN LQCEVNITAD VWRGENSGKS PG WGITLVA QSKQKGWSYF AEDIGDAGSI PEELGEKVAC QLLEEISKSA AVGRNQLPLA IVYMVIGKED IGRLRINKEQ IDE RFIILL RDIKKIFNTE VFLKPVDEAD NEDMIATIKG IGFTNTSKKI A

UniProtKB: RNA 3'-terminal phosphate cyclase-like protein

Macromolecule #51: Bms1

• Macromolecule: Name: Bms1 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 135.152938 KDa

Sequence

String:

MEQSNKQHRK AKEKNTAKKK LHTQGHNAKA FAVAAPGKMA RTMQRSSDVN ERKLHVPMVD RTPEDDPPPF IVAVVGPPGT GKTTLIRSL VRRMTKSTLN DIQGPITVVS GKHRRLTFLE CPADDLNAMI DIAKIADLVL LLIDGNFGFE METMEFLNIA Q HHGMPRVL GVATHLDLFK SQSTLRASKK RLKHRFWTEV YQGAKLFYLS GVINGRYPDR EILNLSRFIS VMKFRPLKWR NE HPYMLAD RFTDLTHPEL IETQGLQIDR KVAIYGYLHG TPLPSAPGTR VHIAGVGDFS VAQIEKLPDP CPTPFYQQKL DDF EREKMK EEAKANGEIT TASTTRRRKR LDDKDKLIYA PMSDVGGVLM DKDAVYIDIG KKNEEPSFVP G(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)FSNGT ELHEV ADHE GMDVESGEES IEDDEGKSKG RTSLRKPRIY GKPVQEEDAD IDNLPSDEEP YTNDDDVQDS EPRMVEIDFN NTGEQG AEK LALETDSEFE ESEDEFSWER TAANKLKKTE SKKRTWNIGK LIYMDNISPE ECIRRWRGED DDSKDESDIE EDVDDDF FR KKDGTVTKEG NKDHAVDLEK FVPYFDTFEK LAKKWKSVDA IKERFLGAGI LGNDNKTKSD SNEGGEELYG DFEDLEDG N PSEQAEDNSD KESEDEDENE DTNGDDDNSF TNFDAEEKKD LTMEQEREMN AAKKEKLRAQ FEIEEGENFK EDDENNEYD TWYELQKAKI SKQLEINNIE YQEMTPEQRQ RIEGFKAGSY VRIVFEKVPM EFVKNFNPKF PIVMGGLLPT EIKFGIVKAR LRRHRWHKK ILKTNDPLVL SLGWRRFQTL PIYTTTDSRT RTRMLKYTPE HTYCNAAFYG PLCSPNTPFC GVQIVANSDT G NGFRIAAT GIVEEIDVNI EIVKKLKLVG FPYKIFKNTA FIKDMFSSAM EVARFEGAQI KTVSGIRGEI KRALSKPEGH YR AAFEDKI LMSDIVILRS WYPVRVKKFY NPVTSLLLKE KTEWKGLRLT GQIRAAMNLE TPSNPDSAYH KIERVERHFN GLK VPKAVQ KELPFKSQIH QMKPQKKKTY MAKRAVVLGG DEKKARSFIQ KVLTISKAKD SKRKEQKASQ RKERLKKLAK MEEE KSQRD KEKKKEYFAQ NGKRTTMGGD DESRPRKMRR

UniProtKB: Ribosome biogenesis protein BMS1, Ribosome biogenesis protein BMS1

Macromolecule #52: Emg1

• Macromolecule: Name: Emg1 / type: protein_or_peptide / ID: 52 / Number of copies: 2 / Enantiomer: LEVO; EC number: rRNA small subunit pseudouridine methyltransferase Nep1
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 27.936461 KDa

Sequence

String:

MVEDSRVRDA LKGGDQKALP ASLVPQAPPV LTSKDKITKR MIVVLAMASL ETHKISSNGP GGDKYVLLNC DDHQGLLKKM GRDISEARP DITHQCLLTL LDSPINKAGK LQVYIQTSRG ILIEVNPTVR IPRTFKRFSG LMVQLLHKLS IRSVNSEEKL L KVIKNPIT DHLPTKCRKV TLSFDAPVIR VQDYIEKLDD DESICVFVGA MARGKDNFAD EYVDEKVGLS NYPLSASVAC SK FCHGAED AWNIL

UniProtKB: Ribosomal RNA small subunit methyltransferase NEP1

Macromolecule #53: Utp24

• Macromolecule: Name: Utp24 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 21.650729 KDa

Sequence

String:

MGKAKKTRKF GLVKRTLNTK KDQRLKKNQE NIKTKEDPEL TRNIPQVSSA LFFQYNQAIK PPYQVLIDTN FINFSIQKKV DIVRGMMDC LLAKCNPLIT DCVMAELEKL GPKYRIALKL ARDPRIKRLS CSHKGTYADD CLVHRVLQHK CYIVATNDAG L KQRIRKIP GIPLMSVGGH AYVIEKLPDV F

UniProtKB: rRNA-processing protein FCF1

Macromolecule #54: Imp4

• Macromolecule: Name: Imp4 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 33.536168 KDa

Sequence

String:

MLRRQARERR EYLYRKAQEL QDSQLQQKRQ IIKQALAQGK PLPKELAEDE SLQKDFRYDQ SLKESEEADD LQVDDEYAAT SGIMDPRII VTTSRDPSTR LSQFAKEIKL LFPNAVRLNR GNYVMPNLVD ACKKSGTTDL VVLHEHRGVP TSLTISHFPH G PTAQFSLH NVVMRHDIIN AGNQSEVNPH LIFDNFTTAL GKRVVCILKH LFNAGPKKDS ERVITFANRG DFISVRQHVY VR TREGVEI AEVGPRFEMR LFELRLGTLE NKDADVEWQL RRFIRTANKK DYL

UniProtKB: U3 small nucleolar ribonucleoprotein protein IMP4

Macromolecule #55: Utp30

• Macromolecule: Name: Utp30 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 31.668939 KDa

Sequence

String:

MVESNDIIKS GLAEKALKAL ILQCEENPSL KNDKDIHIII NTGKKMGINR DNIPRIIPLT KYKLFKPRDL NILLITKDPS ALYRETLTK DEHTSELFKE IISVKNLRRR FKGSKLTQLY KDFDLVVADY RVHHLLPEVL GSRFYHGSKK LPYMIRMSKE V KLKRQQMV EKCDPIYVRA QLRSICKNTS YIPNNDNCLS VRVGYIQKHS IPEILQNIQD TINFLTDKSK RPQGGVIKGG II SIFVKTS NSTSLPIYQF SEARENQKNE DLSDIKL

UniProtKB: Ribosome biogenesis protein UTP30

Macromolecule #56: Pno1

• Macromolecule: Name: Pno1 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 30.380623 KDa

Sequence

String:

MVAPTALKKA TVTPVSGQDG GSSRIIGINN TESIDEDDDD DVLLDDSDNN TAKEEVEGEE GSRKTHESKT VVVDDQGKPR FTSASKTQG NKIKFESRKI MVPPHRMTPL RNSWTKIYPP LVEHLKLQVR MNLKTKSVEL RTNPKFTTDP GALQKGADFI K AFTLGFDL DDSIALLRLD DLYIETFEVK DVKTLTGDHL SRAIGRIAGK DGKTKFAIEN ATRTRIVLAD SKIHILGGFT HI RMARESV VSLILGSPPG KVYGNLRTVA SRLKERY

UniProtKB: Pre-rRNA-processing protein PNO1

Macromolecule #57: Utp20

• Macromolecule: Name: Utp20 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 83.59018 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)

Macromolecule #58: Fcf2

• Macromolecule: Name: Fcf2 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 25.68924 KDa

Sequence

String:

MDQSVEDLFG ALRDASASLE VKNSAKEQVS LQQEDVLQIG NNDDEVEIES KFQEIETNLK KLPKLETGFD ALANKKKKKN VLPSVETED KRKPNKSDKN DNDWFTLPKP DDNMRREVQR DLLLIKHRAA LDPKRHYKKQ RWEVPERFAI GTIIEDKSEF Y SSRMNRKE RKSTILETLM GDEASNKYFK RKYNEIQEKS TSGRKAHYKK MKEMRKKRR

UniProtKB: rRNA-processing protein FCF2

Macromolecule #59: rpS23_uS12

• Macromolecule: Name: rpS23_uS12 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 16.073896 KDa

Sequence

String:

MGKGKPRGLN SARKLRVHRR NNRWAENNYK KRLLGTAFKS SPFGGSSHAK GIVLEKLGIE SKQPNSAIRK CVRVQLIKNG KKVTAFVPN DGCLNFVDEN DEVLLAGFGR KGKAKGDIPG VRFKVVKVSG VSLLALWKEK KEKPRS

UniProtKB: Small ribosomal subunit protein uS12A

Macromolecule #60: Utp14

• Macromolecule: Name: Utp14 / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 101.101461 KDa

Sequence

String:

MAKKKSKSRS KSSRRVLDAL QLAEREINGE FDNSSDNDKR HDARRNGTVV NLLKRSKGDT NSDEDDIDSE SFEDEELNSD EALGSDDDY DILNSKFSQT IRDKKENANY QEEEDEGGYT SIDEEDLMPL SQVWDMDEKT AQSNGNDDED ASPQLKLQDT D ISSESSSS EESESESEDD EEEEDPFDEI SEDEEDIELN TITSKLIDET KSKAPKRLDT YGSGEANEYV LPSANAASGA SG KLSLTDM MNVIDDRQVI ENANLLKGKS STYEVPLPQR IQQRHDRKAA YEISRQEVSK WNDIVQQNRR ADHLIFPLNK PTE HNHASA FTRTQDVPQT ELQEKVDQVL QESN(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)T YRKIKKKELM KNRELAAVSS DEDNEDHDI ARAKERMTLK HKTNSKWAKD MIKHGMTNDA ETREEMEEML RQGERLKAKM LDRNSDDEED GRVQTLSDVE NEEKENIDSE ALKSKLGKT GVMNMAFMKN GEAREREANK ETLRQLRAVE NGDDIKLFES DEEETNGENI QINKGRRIYT PGSLESNKDM N ELNDHTRK ENKVDESRSL ENRLRAKNSG QSKNARTNAE GAIIVEEESD GEPLQDGQNN QQDEEAKDVN PWLANESDEE HT VKKQSSK VNVIDKDSSK NVKAMNKMEK AELKQKKKKK GKSNDDEDLL LTADDSTRLK IVDPYGGSDD EQGDNVFMFK QQD VIAEAF AGDDVVAEFQ EEKKRVIDDE DDKEVDTTLP GWGEWAGAGS KPKNKKRKFI KKVKGVVNKD KRRDKNLQNV IINE KVNKK NLKYQSSAVP FPFENREQYE RSLRMPIGQE WTSRASHQEL IKPRIMTKPG QVIDPLKAPF K

UniProtKB: U3 small nucleolar RNA-associated protein 14, U3 small nucleolar RNA-associated protein 14

Macromolecule #61: Nop14

• Macromolecule: Name: Nop14 / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 85.993961 KDa

Sequence

String:

MAGSQLKNLK AALKARGLTG QTNVKSKNKK NSKRQAKEYD REEKKKAIAE IREEFNPFEI KAARNKRRDG LPSKTADRIA VGKPGISKQ IGEEQRKRAF EARKMMKNKR GGVIDKRFGE RDKLLTEEEK MLERFTRERQ SQSKRNANLF NLEDDEDDGD M FGDGLTHL GQSLSLEDEL ANDEEDFLAS KRFNEDDAEL QQ(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) KEKLG KFTAVLLRHI IFLSNQNYLK NVQSFKRTQN ALISILKSLS EKYNRELSEE CRDYINEMQA RYKKNHFDAL SNGDL VFFS IIGILFSTSD QYHLVITPAL ILMSQFLEQI KFNSLKRIAF GAVLVRIVSQ YQRISKRYIP EVVYFFQKIL LTFIVE KEN QEKPLDFENI RLDSYELGLP LDVDFTKKRS TIIPLHTLST MDTEAHPVDQ CVSVLLNVME SLDATISTVW KSLPAFN EI ILPIQQLLSA YTSKYSDFEK PRNILNKVEK LTKFTEHIPL ALQNHKPVSI PTHAPKYEEN FNPDKKSYDP DRTRSEIN K MKAQLKKERK FTMKEIRKDA KFEARQRIEE KNKESSDYHA KMAHIVNTIN TEEGAEKNKY ERERKLRGGK K

UniProtKB: Nucleolar complex protein 14, Nucleolar complex protein 14

Macromolecule #62: Noc4

• Macromolecule: Name: Noc4 / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 58.369125 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)FRKL IIALWSSNMG EIEDVKSSGA SENLIIVEFT EKYYTKFADI QYYFQSEFNQ LLEDPAYQDL L LKNVGKWL ALVNHDKHCS SVDADLEIFV PNPPQAIENE SKFKSNFEKN WLSLLNGQLS LQQYKSILLI LHKRIIPHFH TP TKLMDFL TDSYNLQSSN KNAGVVPILA LNGLFELMKR FNLEYPNFYM KLYQIINPDL MHVKYRARFF RLMDVFLSST HLS AHLVAS FIKKLARLTL ESPPSAIVTV IPFIYNLIRK HPNCMIMLHN PAFISNPFQT PDQVANLKTL KENYVDPFDV HESD PELTH ALDSSLWELA SLMEHYHPNV ATLAKIFAQP FKKLSYNMED FLDWNYDSLL NAESSR(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)

UniProtKB: Nucleolar complex protein 4

Macromolecule #63: Rrt14

• Macromolecule: Name: Rrt14 / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 21.036877 KDa

Sequence

String:

MSSSLSQTSK YQATSVVNGL LSNLLPGVPK IRANNGKTSV NNGSKAQLID RNLKKRVQLQ NRDVHKIKKK CKLVKKKKVK KHKLDKEQL EQLAKHQVLK K(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)FVKDHRY PGLTPGLAPV GLSDEEDSSE ED

UniProtKB: Regulator of rDNA transcription 14, Regulator of rDNA transcription 14

Macromolecule #64: Unassigned peptides

• Macromolecule: Name: Unassigned peptides / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 8.783818 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #65: Utp11

• Macromolecule: Name: Utp11 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 29.806348 KDa

Sequence

String:

MAKLVHDVQK KQHRERSQLT SRSRYGFLEK HKDYVKRAQD FHRKQSTLKV LREKAKERNP DEYYHAMHSR KTDAKGLLIS SRHGDEEDE SLSMDQVKLL KTQDSNYVRT LRQIELKKLE KGAKQLMFKS SGNHTIFVDS REKMNEFTPE KFFNTTSEMV N RSENRLTK DQLAQDISNN RNASSIMPKE SLDKKKLKKF KQVKQHLQRE TQLKQVQQRM DAQRELLKKG SKKKIVDSSG KI SFKWKKQ RKR

UniProtKB: U3 small nucleolar RNA-associated protein 11

Macromolecule #66: Enp1

• Macromolecule: Name: Enp1 / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Saccharomyces cerevisiae BY4741 (yeast) / Strain: BY4741
• Molecular weight: Theoretical: 55.207422 KDa

Sequence

String:

MARASSTKAR KQRHDPLLKD LDAAQGTLKK INKKKLAQND AANHDAANEE DGYIDSKASR KILQLAKEQQ DEIEGEELAE SERNKQFEA RFTTMSYDDE DEDEDEDEEA FGEDISDFEP EGDYKEEEEI VEIDEEDAAM FEQYFKKSDD FNSLSGSYNL A DKIMASIR EKESQVEDMQ DDEPLANEQN TSRGNISSGL KSGEGVALPE KVIKAYTTVG SILKTWTHGK LPKLFKVIPS LR NWQDVIY VTNPEEWSPH VVYEATKLFV SNLTAKESQK FINLILLERF RDNIETSEDH SLNYHIYRAV KKSLYKPSAF FKG FLFPLV ETGCNVREAT IAGSVLAKVS VPALHSSAAL SYLLRLPFSP PTTVFIKILL DKKYALPYQT VDDCVYYFMR FRIL DDGSN GEDATRVLPV IWHKAFLTFA QRYKNDITQD QRDFLLETVR QRGHKDIGPE IRRELLAGAS REFVDPQEAN DDLMI DVN

UniProtKB: Essential nuclear protein 1

Macromolecule #67: ZINC ION

• Macromolecule: Name: ZINC ION / type: ligand / ID: 67 / Number of copies: 1 / Formula: ZN
• Molecular weight: Theoretical: 65.409 Da

Experimental details

Structure determination

• Method: cryo EM
• Processing: single particle reconstruction
• Aggregation state: particle

Sample preparation

• Concentration: 0.15 mg/mL

Buffer

pH: 7.7
Component:

Concentration	Formula	Name
50.0 mM	(HOCH2)3CNH2	Tris
150.0 mM	NaClSodium chloride	sodium chloride
1.0 mM	(HO2CCH2)2NCH2CH2N(CH2CO2H)2	EDTAEthylenediaminetetraacetic acid
0.1 %		Triton X-100
5.0 mM		biotin

• Grid: Model: Ted Pella Inc. / Material: COPPER / Mesh: 400 / Support film - #0 - Film type ID: 1 / Support film - #0 - Material: CARBON / Support film - #0 - topology: LACEY / Support film - #1 - Film type ID: 2 / Support film - #1 - Material: CARBON / Support film - #1 - topology: CONTINUOUS / Support film - #1 - Film thickness: 2 / Pretreatment - Type: GLOW DISCHARGE / Pretreatment - Time: 30 sec. / Pretreatment - Atmosphere: AIR / Details: 50 mA
• Vitrification: Cryogen name: ETHANE / Chamber humidity: 100 % / Chamber temperature: 295 K / Instrument: FEI VITROBOT MARK IV

Electron microscopy

• Microscope: FEI TITAN KRIOS
• Electron beam: Acceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
• Electron optics: Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELDBright-field microscopy / Nominal defocus max: 2.6 µm / Nominal defocus min: 0.6 µm / Nominal magnification: 22500
• Sample stage: Specimen holder model: FEI TITAN KRIOS AUTOGRID HOLDER / Cooling holder cryogen: NITROGEN
• Image recording: Film or detector model: GATAN K2 SUMMIT (4k x 4k) / Detector mode: SUPER-RESOLUTION / Number grids imaged: 4 / Number real images: 10029 / Average exposure time: 0.25 sec. / Average electron dose: 1.56 e/Ų
• Experimental equipment: Model: Titan Krios / Image courtesy: FEI Company

Image processing

• Particle selection: Number selected: 772120

Startup model

Type of model: EMDB MAP
EMDB ID:

8473

• Initial angle assignment: Type: PROJECTION MATCHING / Software - Name: RELION (ver. 2)
• Final 3D classification: Number classes: 5 / Software - Name: RELION (ver. 2)
• Final angle assignment: Type: PROJECTION MATCHING / Software - Name: RELION (ver. 2)
• Final reconstruction: Number classes used: 2 / Applied symmetry - Point group: C₁ (asymmetric) / Resolution.type: BY AUTHOR / Resolution: 3.8 Å / Resolution method: FSC 0.143 CUT-OFF / Software - Name: RELION (ver. 2) / Number images used: 284213

Atomic model buiding 1

• Refinement: Space: REAL / Protocol: OTHER / Overall B value: 338.9

Output model

PDB-5wlc:
The complete structure of the small subunit processome