[日本語] English
万見
- PDB-6hhq: Crystal structure of compound C45 bound to the yeast 80S ribosome -

+
データを開く


IDまたはキーワード:

読み込み中...

-
基本情報

登録情報
データベース: PDB / ID: 6hhq
タイトルCrystal structure of compound C45 bound to the yeast 80S ribosome
要素
  • (18S ribosomal ...) x 2
  • (40S ribosomal protein ...) x 31
  • (60S ribosomal protein ...) x 40
  • 25S ribosomal RNA
  • 5.8S ribosomal RNA
  • 5S ribosomal RNA
  • 60S acidic ribosomal protein P0
  • Guanine nucleotide-binding protein subunit beta-like protein
  • Suppressor protein STM1
  • Ubiquitin-40S ribosomal protein S31
  • Ubiquitin-60S ribosomal protein L40
キーワードRIBOSOME / 80S ribosome / inhibitor / anti-cancer
機能・相同性
機能・相同性情報


triplex DNA binding / ribosome hibernation / translation elongation factor binding / regulation of translational initiation in response to stress / Platelet degranulation / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / negative regulation of glucose mediated signaling pathway / negative regulation of translational frameshifting / Negative regulators of DDX58/IFIH1 signaling / positive regulation of translational fidelity ...triplex DNA binding / ribosome hibernation / translation elongation factor binding / regulation of translational initiation in response to stress / Platelet degranulation / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) / negative regulation of glucose mediated signaling pathway / negative regulation of translational frameshifting / Negative regulators of DDX58/IFIH1 signaling / positive regulation of translational fidelity / Protein methylation / RMTs methylate histone arginines / mTORC1-mediated signalling / Protein hydroxylation / ribosome-associated ubiquitin-dependent protein catabolic process / GDP-dissociation inhibitor activity / positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay / pre-mRNA 5'-splice site binding / Formation of the ternary complex, and subsequently, the 43S complex / Translation initiation complex formation / Ribosomal scanning and start codon recognition / translational elongation / cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / preribosome, small subunit precursor / response to cycloheximide / telomeric DNA binding / mRNA destabilization / Major pathway of rRNA processing in the nucleolus and cytosol / SRP-dependent cotranslational protein targeting to membrane / GTP hydrolysis and joining of the 60S ribosomal subunit / Formation of a pool of free 40S subunits / Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) / Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) / negative regulation of mRNA splicing, via spliceosome / L13a-mediated translational silencing of Ceruloplasmin expression / preribosome, large subunit precursor / ribosomal large subunit export from nucleus / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / G-protein alpha-subunit binding / TOR signaling / positive regulation of protein kinase activity / protein-RNA complex assembly / regulation of translational fidelity / Ub-specific processing proteases / ribosomal small subunit export from nucleus / translation regulator activity / ribosomal subunit export from nucleus / translational termination / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / translation repressor activity / DNA-(apurinic or apyrimidinic site) endonuclease activity / cellular response to amino acid starvation / telomere maintenance / ribosome assembly / rescue of stalled ribosome / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / 90S preribosome / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / ribosomal large subunit biogenesis / maturation of SSU-rRNA / macroautophagy / small-subunit processome / positive regulation of apoptotic signaling pathway / protein kinase C binding / maintenance of translational fidelity / ribosomal large subunit assembly / cytoplasmic stress granule / modification-dependent protein catabolic process / rRNA processing / protein tag activity / ribosome biogenesis / ribosome binding / ribosomal small subunit biogenesis / ribosomal small subunit assembly / small ribosomal subunit / small ribosomal subunit rRNA binding / 5S rRNA binding / large ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / cytosolic large ribosomal subunit / cytoplasmic translation / rRNA binding / negative regulation of translation / ribosome / protein ubiquitination / structural constituent of ribosome / translation / positive regulation of protein phosphorylation / G protein-coupled receptor signaling pathway / negative regulation of gene expression / response to antibiotic / mRNA binding / ubiquitin protein ligase binding / nucleolus / negative regulation of apoptotic process / perinuclear region of cytoplasm / mitochondrion / DNA binding / RNA binding
類似検索 - 分子機能
Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / : ...Stm1-like, N-terminal / Stm1 / Hyaluronan/mRNA-binding protein / Hyaluronan / mRNA binding family / 60s Acidic ribosomal protein / 60S acidic ribosomal protein P0 / 50S ribosomal protein L10, insertion domain superfamily / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / : / Ribosomal protein S26e signature. / : / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein S12e signature. / Ribosomal protein S12e / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S2, eukaryotic / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein L29e / Ribosomal L29e protein family / 40S Ribosomal protein S10 / S27a-like superfamily / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein S2, eukaryotic/archaeal / : / Ribosomal protein S17e, conserved site / Ribosomal protein S17e signature. / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein S30 / Ribosomal protein S30 / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein S7e signature. / Ribosomal protein L44e signature. / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal protein L10e / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein L19, eukaryotic / Ribosomal protein S19e / Ribosomal protein S3Ae, conserved site / Ribosomal protein S19e / Ribosomal protein S3Ae signature. / Ribosomal_S19e / Ribosomal protein S27e signature. / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S4e, N-terminal, conserved site / Ribosomal protein S4e signature. / 40S ribosomal protein S4, C-terminal domain / 40S ribosomal protein S4 C-terminus / : / Ribosomal protein S19A/S15e / Ribosomal protein S8e, conserved site / Ribosomal protein S8e signature. / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Ribosomal protein L44e / Ribosomal protein L19/L19e conserved site / Ribosomal protein L44 / Ribosomal protein L19e signature. / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein S17e / Ribosomal protein S17e-like superfamily / Ribosomal S17 / Ribosomal protein L6e signature. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal L40e family / Ribosomal protein L30e signature 1.
類似検索 - ドメイン・相同性
Chem-G5B / osmium (III) hexammine / : / : / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) ...Chem-G5B / osmium (III) hexammine / : / : / : / : / RNA / RNA (> 10) / RNA (> 100) / RNA (> 1000) / Small ribosomal subunit protein uS4A / Large ribosomal subunit protein uL15 / Small ribosomal subunit protein eS17A / Large ribosomal subunit protein eL24A / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL30A / Large ribosomal subunit protein uL6A / Large ribosomal subunit protein uL22A / Large ribosomal subunit protein uL24A / Large ribosomal subunit protein eL33A / Large ribosomal subunit protein eL36A / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL15A / Large ribosomal subunit protein eL22A / Small ribosomal subunit protein uS3 / Small ribosomal subunit protein uS15 / Ubiquitin-ribosomal protein eS31 fusion protein / Small ribosomal subunit protein eS19A / Small ribosomal subunit protein eS21A / Small ribosomal subunit protein uS8A / Large ribosomal subunit protein eL27A / Large ribosomal subunit protein eL31A / Ubiquitin-ribosomal protein eL40A fusion protein / Large ribosomal subunit protein eL20A / Large ribosomal subunit protein eL43A / Large ribosomal subunit protein eL42A / Small ribosomal subunit protein uS12A / Small ribosomal subunit protein eS24A / Small ribosomal subunit protein eS30A / Small ribosomal subunit protein eS4A / Small ribosomal subunit protein eS6A / Small ribosomal subunit protein eS8A / Large ribosomal subunit protein uL14A / Large ribosomal subunit protein uL2A / Small ribosomal subunit protein uS17A / Large ribosomal subunit protein eL18A / Small ribosomal subunit protein uS9A / Small ribosomal subunit protein uS13A / Large ribosomal subunit protein eL19A / Large ribosomal subunit protein uL29A / Small ribosomal subunit protein eS32B / Large ribosomal subunit protein uL4A / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL8A / Small ribosomal subunit protein uS5 / Large ribosomal subunit protein uL18 / Small ribosomal subunit protein uS7 / Large ribosomal subunit protein uL13A / Small ribosomal subunit protein eS7A / Small ribosomal subunit protein uS2A / Small ribosomal subunit protein eS1A / Small ribosomal subunit protein eS27A / Large ribosomal subunit protein eL14A / Small ribosomal subunit protein RACK1 / Large ribosomal subunit protein eL32 / Small ribosomal subunit protein uS10 / Suppressor protein STM1 / Small ribosomal subunit protein uS11B / Small ribosomal subunit protein eS26B / Small ribosomal subunit protein uS14A / Large ribosomal subunit protein uL16 / Small ribosomal subunit protein eS12 / Large ribosomal subunit protein eL37A / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL34A / Small ribosomal subunit protein uS19 / Large ribosomal subunit protein eL6A / Large ribosomal subunit protein eL21A / Small ribosomal subunit protein eS10A / Large ribosomal subunit protein eL13A / Large ribosomal subunit protein uL5B / Small ribosomal subunit protein eS25A / Small ribosomal subunit protein eS28A
類似検索 - 構成要素
生物種Saccharomyces cerevisiae (パン酵母)
手法X線回折 / シンクロトロン / 解像度: 3.10000049683 Å
データ登録者Pellegrino, S. / Vanderwal, C.D. / Yusupov, M.
資金援助 フランス, 米国, 5件
組織認可番号国
French National Research AgencyANR-15-CE11-0021-01 フランス
FRM - DBF20160635745 フランス
European Research Council294312
NIH - GM079238 米国
NIH - GM129264 米国
引用ジャーナル: Nucleic Acids Res. / 年: 2019
タイトル: Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
著者: Pellegrino, S. / Meyer, M. / Konst, Z.A. / Holm, M. / Voora, V.K. / Kashinskaya, D. / Zanette, C. / Mobley, D.L. / Yusupova, G. / Vanderwal, C.D. / Blanchard, S.C. / Yusupov, M.
履歴
登録2018年8月28日登録サイト: PDBE / 処理サイト: PDBE
改定 1.02019年2月20日Provider: repository / タイプ: Initial release
改定 1.12019年2月27日Group: Data collection / Database references
カテゴリ: citation / citation_author ...citation / citation_author / database_PDB_rev / database_PDB_rev_record / pdbx_database_proc
Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year
改定 1.22019年4月17日Group: Data collection / Database references / カテゴリ: citation / pdbx_database_proc
Item: _citation.journal_volume / _citation.page_first / _citation.page_last
改定 1.32024年5月15日Group: Data collection / Database references / Derived calculations
カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_auth_comp_id / _pdbx_struct_conn_angle.ptnr2_auth_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr2_label_atom_id / _pdbx_struct_conn_angle.ptnr2_label_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id

-
構造の表示

構造ビューア分子:
MolmilJmol/JSmol

ダウンロードとリンク

-
集合体

登録構造単位
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: 60S ribosomal protein L11-B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
6: 60S ribosomal protein L23-A
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-B
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: 60S ribosomal protein L11-B
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-B
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
p0: 60S acidic ribosomal protein P0
sM: Suppressor protein STM1
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: 40S ribosomal protein S3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-A
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: 40S ribosomal protein S20
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: 40S ribosomal protein S26-B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: 40S ribosomal protein S29-A
f: 40S ribosomal protein S30-A
g: Ubiquitin-40S ribosomal protein S31
h: Guanine nucleotide-binding protein subunit beta-like protein
sR: 18S ribosomal RNA
Rb: Guanine nucleotide-binding protein subunit beta-like protein
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: 40S ribosomal protein S3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: 40S ribosomal protein S20
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: 40S ribosomal protein S26-B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: 40S ribosomal protein S29-A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin-40S ribosomal protein S31
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)6,646,1652745
ポリマ－6,304,765159
非ポリマー341,3992586
水00
1
1: 25S ribosomal RNA
3: 5S ribosomal RNA
4: 5.8S ribosomal RNA
j: 60S ribosomal protein L2-A
k: 60S ribosomal protein L3
l: 60S ribosomal protein L4-A
m: 60S ribosomal protein L5
n: 60S ribosomal protein L6-A
o: 60S ribosomal protein L7-A
p: 60S ribosomal protein L8-A
q: 60S ribosomal protein L9-A
r: 60S ribosomal protein L10
s: 60S ribosomal protein L11-B
t: 60S ribosomal protein L13-A
u: 60S ribosomal protein L14-A
v: 60S ribosomal protein L15-A
w: 60S ribosomal protein L16-A
x: 60S ribosomal protein L17-A
y: 60S ribosomal protein L18-A
z: 60S ribosomal protein L19-A
0: 60S ribosomal protein L20-A
2: 60S ribosomal protein L21-A
5: 60S ribosomal protein L22-A
6: 60S ribosomal protein L23-A
7: 60S ribosomal protein L24-A
8: 60S ribosomal protein L25
9: 60S ribosomal protein L26-A
AA: 60S ribosomal protein L27-A
AB: 60S ribosomal protein L28
AC: 60S ribosomal protein L29
AD: 60S ribosomal protein L30
AE: 60S ribosomal protein L31-A
AF: 60S ribosomal protein L32
AG: 60S ribosomal protein L33-A
AH: 60S ribosomal protein L34-A
AI: 60S ribosomal protein L35-A
AJ: 60S ribosomal protein L36-A
AK: 60S ribosomal protein L37-A
AL: 60S ribosomal protein L38
AM: 60S ribosomal protein L39
AN: Ubiquitin-60S ribosomal protein L40
AO: 60S ribosomal protein L41-B
AP: 60S ribosomal protein L42-A
AQ: 60S ribosomal protein L43-A
i: Suppressor protein STM1
A: 18S ribosomal RNA
B: 40S ribosomal protein S0-A
C: 40S ribosomal protein S1-A
D: 40S ribosomal protein S2
E: 40S ribosomal protein S3
F: 40S ribosomal protein S4-A
G: 40S ribosomal protein S5
H: 40S ribosomal protein S6-A
I: 40S ribosomal protein S7-A
J: 40S ribosomal protein S8-A
K: 40S ribosomal protein S9-A
L: 40S ribosomal protein S10-A
M: 40S ribosomal protein S11-A
N: 40S ribosomal protein S12
O: 40S ribosomal protein S13
P: 40S ribosomal protein S14-B
Q: 40S ribosomal protein S15
R: 40S ribosomal protein S16-A
S: 40S ribosomal protein S17-A
T: 40S ribosomal protein S18-A
U: 40S ribosomal protein S19-A
V: 40S ribosomal protein S20
W: 40S ribosomal protein S21-A
X: 40S ribosomal protein S22-A
Y: 40S ribosomal protein S23-A
Z: 40S ribosomal protein S24-A
a: 40S ribosomal protein S25-A
b: 40S ribosomal protein S26-B
c: 40S ribosomal protein S27-A
d: 40S ribosomal protein S28-A
e: 40S ribosomal protein S29-A
f: 40S ribosomal protein S30-A
g: Ubiquitin-40S ribosomal protein S31
h: Guanine nucleotide-binding protein subunit beta-like protein
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)3,300,2951318
ポリマ－3,135,03779
非ポリマー165,2581239
水0
タイプ名称対称操作数
identity operation1_555x,y,z1
2
AR: 25S ribosomal RNA
AS: 5S ribosomal RNA
AT: 5.8S ribosomal RNA
CD: 60S ribosomal protein L2-A
CE: 60S ribosomal protein L3
CF: 60S ribosomal protein L4-A
CG: 60S ribosomal protein L5
CH: 60S ribosomal protein L6-A
CI: 60S ribosomal protein L7-A
CJ: 60S ribosomal protein L8-A
CK: 60S ribosomal protein L9-A
CL: 60S ribosomal protein L10
CM: 60S ribosomal protein L11-B
CN: 60S ribosomal protein L13-A
CO: 60S ribosomal protein L14-A
CP: 60S ribosomal protein L15-A
CQ: 60S ribosomal protein L16-A
CR: 60S ribosomal protein L17-A
CS: 60S ribosomal protein L18-A
CT: 60S ribosomal protein L19-A
CU: 60S ribosomal protein L20-A
CV: 60S ribosomal protein L21-A
CW: 60S ribosomal protein L22-A
CX: 60S ribosomal protein L23-A
CY: 60S ribosomal protein L24-A
CZ: 60S ribosomal protein L25
DA: 60S ribosomal protein L26-A
DB: 60S ribosomal protein L27-A
DC: 60S ribosomal protein L28
DD: 60S ribosomal protein L29
DE: 60S ribosomal protein L30
DF: 60S ribosomal protein L31-A
DG: 60S ribosomal protein L32
DH: 60S ribosomal protein L33-A
DI: 60S ribosomal protein L34-A
DJ: 60S ribosomal protein L35-A
DK: 60S ribosomal protein L36-A
DL: 60S ribosomal protein L37-A
DM: 60S ribosomal protein L38
DN: 60S ribosomal protein L39
DO: Ubiquitin-60S ribosomal protein L40
DP: 60S ribosomal protein L41-B
DQ: 60S ribosomal protein L42-A
DR: 60S ribosomal protein L43-A
p0: 60S acidic ribosomal protein P0
sM: Suppressor protein STM1
sR: 18S ribosomal RNA
Rb: Guanine nucleotide-binding protein subunit beta-like protein
s0: 40S ribosomal protein S0-A
s1: 40S ribosomal protein S1-A
s2: 40S ribosomal protein S2
s3: 40S ribosomal protein S3
s4: 40S ribosomal protein S4-A
s5: 40S ribosomal protein S5
s6: 40S ribosomal protein S6-A
s7: 40S ribosomal protein S7-A
s8: 40S ribosomal protein S8-A
s9: 40S ribosomal protein S9-A
c0: 40S ribosomal protein S10-A
c1: 40S ribosomal protein S11-A
c2: 40S ribosomal protein S12
c3: 40S ribosomal protein S13
c4: 40S ribosomal protein S14-B
c5: 40S ribosomal protein S15
c6: 40S ribosomal protein S16-A
c7: 40S ribosomal protein S17-A
c8: 40S ribosomal protein S18-A
c9: 40S ribosomal protein S19-A
d0: 40S ribosomal protein S20
d1: 40S ribosomal protein S21-A
d2: 40S ribosomal protein S22-A
d3: 40S ribosomal protein S23-A
d4: 40S ribosomal protein S24-A
d5: 40S ribosomal protein S25-A
d6: 40S ribosomal protein S26-B
d7: 40S ribosomal protein S27-A
d8: 40S ribosomal protein S28-A
d9: 40S ribosomal protein S29-A
e0: 40S ribosomal protein S30-A
e1: Ubiquitin-40S ribosomal protein S31
ヘテロ分子


分子量 (理論値)分子数
合計 (水以外)3,345,8701427
ポリマ－3,169,72880
非ポリマー176,1421347
水0
タイプ名称対称操作数
identity operation1_555x,y,z1
単位格子
Length a, b, c (Å)303.770, 287.950, 435.450
Angle α, β, γ (deg.)90.000, 98.958, 90.000
Int Tables number4
Space group name H-MP1211
Space group name HallP2yb
Symmetry operation#1: x,y,z
#2: -x,y+1/2,-z

-
要素

-
RNA鎖 , 3種, 6分子 1AR3AS4AT

#1: RNA鎖 25S ribosomal RNA


分子量: 1097493.875 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 834774822
#2: RNA鎖 5S ribosomal RNA


分子量: 38951.105 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 1329886537
#3: RNA鎖 5.8S ribosomal RNA


分子量: 50682.922 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 1398978137

+
60S ribosomal protein ... , 40種, 80分子 jCDkCElCFmCGnCHoCIpCJqCKrCLsCMtCNuCOvCPwCQxCR...

#4: タンパク質 60S ribosomal protein L2-A / L5 / Large ribosomal subunit protein uL2-A / RP8 / YL6


分子量: 27463.574 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX45
#5: タンパク質 60S ribosomal protein L3 / Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin ...Large ribosomal subunit protein uL3 / Maintenance of killer protein 8 / RP1 / Trichodermin resistance protein / YL1


分子量: 43850.793 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P14126
#6: タンパク質 60S ribosomal protein L4-A / L2 / Large ribosomal subunit protein uL4-A / RP2 / YL2


分子量: 39159.125 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P10664
#7: タンパク質 60S ribosomal protein L5 / L1 / L1a / Large ribosomal subunit protein uL18 / Ribosomal 5S RNA-binding protein / YL3


分子量: 33764.828 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26321
#8: タンパク質 60S ribosomal protein L6-A / L17 / Large ribosomal subunit protein eL6-A / RP18 / YL16


分子量: 20000.564 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q02326
#9: タンパク質 60S ribosomal protein L7-A / L6 / Large ribosomal subunit protein uL30-A / RP11 / YL8


分子量: 27686.281 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05737
#10: タンパク質 60S ribosomal protein L8-A / L4 / L4-2 / L7a-1 / Large ribosomal subunit protein eL8-A / Maintenance of killer protein 7 / RP6 / YL5


分子量: 28175.820 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P17076
#11: タンパク質 60S ribosomal protein L9-A / L8 / Large ribosomal subunit protein uL6-A / RP24 / YL11


分子量: 21605.061 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05738
#12: タンパク質 60S ribosomal protein L10 / L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI- ...L9 / Large ribosomal subunit protein uL16 / Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein


分子量: 25410.465 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P41805
#13: タンパク質 60S ribosomal protein L11-B / L16 / Large ribosomal subunit protein uL5-B / RP39 / YL22


分子量: 19785.719 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E757
#14: タンパク質 60S ribosomal protein L13-A / Large ribosomal subunit protein eL13-A


分子量: 22604.164 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q12690
#15: タンパク質 60S ribosomal protein L14-A / Large ribosomal subunit protein eL14-A


分子量: 15195.066 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P36105
#16: タンパク質 60S ribosomal protein L15-A / L13 / Large ribosomal subunit protein eL15-A / RP15R / YL10 / YP18


分子量: 24482.357 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05748
#17: タンパク質 60S ribosomal protein L16-A / L13a / L21 / Large ribosomal subunit protein uL13-A / RP22 / YL15


分子量: 22247.227 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26784
#18: タンパク質 60S ribosomal protein L17-A / L20A / Large ribosomal subunit protein uL22-A / YL17


分子量: 20589.518 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05740
#19: タンパク質 60S ribosomal protein L18-A / Large ribosomal subunit protein eL18-A / RP28


分子量: 20609.252 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX49
#20: タンパク質 60S ribosomal protein L19-A / L23 / Large ribosomal subunit protein eL19-A / RP15L / RP33 / YL14


分子量: 21762.316 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX82
#21: タンパク質 60S ribosomal protein L20-A / L18a / Large ribosomal subunit protein eL20-A


分子量: 20478.852 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX23
#22: タンパク質 60S ribosomal protein L21-A / Large ribosomal subunit protein eL21-A


分子量: 18279.266 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q02753
#23: タンパク質 60S ribosomal protein L22-A / L1c / Large ribosomal subunit protein eL22-A / RP4 / YL31


分子量: 13711.359 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05749
#24: タンパク質 60S ribosomal protein L23-A / L17a / Large ribosomal subunit protein uL14-A / YL32


分子量: 14493.950 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX41
#25: タンパク質 60S ribosomal protein L24-A / L30 / Large ribosomal subunit protein eL24-A / RP29 / YL21


分子量: 17661.717 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04449
#26: タンパク質 60S ribosomal protein L25 / Large ribosomal subunit protein uL23 / RP16L / YL25 / YP42'


分子量: 15787.612 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04456
#27: タンパク質 60S ribosomal protein L26-A / L33 / Large ribosomal subunit protein uL24-A / YL33


分子量: 14265.784 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05743
#28: タンパク質 60S ribosomal protein L27-A / Large ribosomal subunit protein eL27-A


分子量: 15568.360 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C2H6
#29: タンパク質 60S ribosomal protein L28 / L27a / L29 / Large ribosomal subunit protein uL15 / RP44 / RP62 / YL24


分子量: 16761.666 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P02406
#30: タンパク質 60S ribosomal protein L29 / Large ribosomal subunit protein eL29 / YL43


分子量: 6691.884 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05747
#31: タンパク質 60S ribosomal protein L30 / L32 / Large ribosomal subunit protein eL30 / RP73 / YL38


分子量: 11430.364 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P14120
#32: タンパク質 60S ribosomal protein L31-A / L34 / Large ribosomal subunit protein eL31-A / YL28


分子量: 12980.158 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C2H8
#33: タンパク質 60S ribosomal protein L32 / Large ribosomal subunit protein eL32


分子量: 14809.441 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38061
#34: タンパク質 60S ribosomal protein L33-A / L37 / Large ribosomal subunit protein eL33-A / RP47 / YL37


分子量: 12177.130 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05744
#35: タンパク質 60S ribosomal protein L34-A / Large ribosomal subunit protein eL34-A


分子量: 13673.196 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P87262
#36: タンパク質 60S ribosomal protein L35-A / Large ribosomal subunit protein uL29-A


分子量: 13942.640 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX84
#37: タンパク質 60S ribosomal protein L36-A / L39 / Large ribosomal subunit protein eL36-A / YL39


分子量: 11151.259 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05745
#38: タンパク質 60S ribosomal protein L37-A / L43 / Large ribosomal subunit protein eL37-A / YL35 / YP55


分子量: 9877.395 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P49166
#39: タンパク質 60S ribosomal protein L38 / Large ribosomal subunit protein eL38


分子量: 8845.561 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P49167
#40: タンパク質 60S ribosomal protein L39 / L46 / Large ribosomal subunit protein eL39 / YL40


分子量: 6358.640 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P04650
#42: タンパク質・ペプチド 60S ribosomal protein L41-B / L47 / Large ribosomal subunit protein eL41-B / YL41


分子量: 3354.243 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX87
#43: タンパク質 60S ribosomal protein L42-A / L41 / Large ribosomal subunit protein eL42-A / YL27 / YP44


分子量: 12246.658 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX27
#44: タンパク質 60S ribosomal protein L43-A / L37a / Large ribosomal subunit protein eL43-A / YL35


分子量: 10112.952 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX25

-
タンパク質 , 5種, 9分子 ANDOisMp0ge1hRb

#41: タンパク質 Ubiquitin-60S ribosomal protein L40


分子量: 14583.077 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CH08
#45: タンパク質 Suppressor protein STM1 / 3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / ...3BP1 / GU4 nucleic-binding protein 2 / G4p2 protein / POP2 multicopy suppressor protein 4 / Ribosomal subunits association factor / AF / TOM1 suppressor protein 1 / Triplex-binding protein 1


分子量: 30048.010 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39015
#46: タンパク質 60S acidic ribosomal protein P0 / A0 / L10e / Large ribosomal subunit protein uL10


分子量: 33749.121 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05317
#79: タンパク質 Ubiquitin-40S ribosomal protein S31


分子量: 17254.227 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05759
#80: タンパク質 Guanine nucleotide-binding protein subunit beta-like protein / Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ...Receptor for activated C kinase / Receptor of activated protein kinase C 1 / RACK1 / Small ribosomal subunit protein RACK1


分子量: 34841.219 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38011

-
18S ribosomal ... , 2種, 2分子 AsR

#47: RNA鎖 18S ribosomal RNA


分子量: 578820.375 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 1329886537
#81: RNA鎖 18S ribosomal RNA


分子量: 579761.938 Da / 分子数: 1 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: GenBank: 874346701

+
40S ribosomal protein ... , 31種, 62分子 Bs0Cs1Ds2Es3Fs4Gs5Hs6Is7Js8Ks9Lc0Mc1Nc2Oc3Pc4...

#48: タンパク質 40S ribosomal protein S0-A / Nucleic acid-binding protein NAB1A / Small ribosomal subunit protein uS2-A


分子量: 28051.330 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P32905
#49: タンパク質 40S ribosomal protein S1-A / RP10A / Small ribosomal subunit protein eS1-A


分子量: 28798.467 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P33442
#50: タンパク質 40S ribosomal protein S2 / Omnipotent suppressor protein SUP44 / RP12 / S4 / Small ribosomal subunit protein uS5 / YS5


分子量: 27490.826 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P25443
#51: タンパク質 40S ribosomal protein S3 / RP13 / Small ribosomal subunit protein uS3 / YS3


分子量: 26542.789 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05750
#52: タンパク質 40S ribosomal protein S4-A / RP5 / S7 / Small ribosomal subunit protein eS4-A / YS6


分子量: 29469.330 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX35
#53: タンパク質 40S ribosomal protein S5 / RP14 / S2 / Small ribosomal subunit protein uS7 / YS8


分子量: 25072.600 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26783
#54: タンパク質 40S ribosomal protein S6-A / RP9 / S10 / Small ribosomal subunit protein eS6-A / YS4


分子量: 27054.486 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX37
#55: タンパク質 40S ribosomal protein S7-A / RP30 / RP40 / Small ribosomal subunit protein eS7-A


分子量: 21658.209 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P26786
#56: タンパク質 40S ribosomal protein S8-A / RP19 / S14 / Small ribosomal subunit protein eS8-A / YS9


分子量: 22537.803 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX39
#57: タンパク質 40S ribosomal protein S9-A / RP21 / S13 / Small ribosomal subunit protein uS4-A / YP28 / YS11


分子量: 22487.893 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: O13516
#58: タンパク質 40S ribosomal protein S10-A / Small ribosomal subunit protein eS10-A


分子量: 12757.445 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q08745
#59: タンパク質 40S ribosomal protein S11-A / RP41 / S18 / Small ribosomal subunit protein uS17-A / YS12


分子量: 17785.934 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX47
#60: タンパク質 40S ribosomal protein S12 / Small ribosomal subunit protein eS12


分子量: 15488.631 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P48589
#61: タンパク質 40S ribosomal protein S13 / S27a / Small ribosomal subunit protein uS15 / YS15


分子量: 17059.945 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P05756
#62: タンパク質 40S ribosomal protein S14-B / RP59B / Small ribosomal subunit protein uS11-B


分子量: 14675.771 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39516
#63: タンパク質 40S ribosomal protein S15 / RIG protein / RP52 / S21 / Small ribosomal subunit protein uS19 / YS21


分子量: 16031.907 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q01855
#64: タンパク質 40S ribosomal protein S16-A / RP61R / Small ribosomal subunit protein uS9-A


分子量: 15877.490 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX51
#65: タンパク質 40S ribosomal protein S17-A / RP51A / Small ribosomal subunit protein eS17-A


分子量: 15820.413 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P02407
#66: タンパク質 40S ribosomal protein S18-A / Small ribosomal subunit protein uS13-A


分子量: 17071.641 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX55
#67: タンパク質 40S ribosomal protein S19-A / RP55A / S16a / Small ribosomal subunit protein eS19-A / YP45 / YS16A


分子量: 15942.125 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P07280
#68: タンパク質 40S ribosomal protein S20 / Small ribosomal subunit protein uS10


分子量: 13929.044 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P38701
#69: タンパク質 40S ribosomal protein S21-A / S26 / Small ribosomal subunit protein eS21-A / YS25


分子量: 9758.829 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C0V8
#70: タンパク質 40S ribosomal protein S22-A / RP50 / S24 / Small ribosomal subunit protein uS8-A / YP58 / YS22


分子量: 14650.062 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0C0W1
#71: タンパク質 40S ribosomal protein S23-A / RP37 / S28 / Small ribosomal subunit protein uS12-A / YS14


分子量: 16073.896 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX29
#72: タンパク質 40S ribosomal protein S24-A / RP50 / Small ribosomal subunit protein eS24-A


分子量: 15362.848 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX31
#73: タンパク質 40S ribosomal protein S25-A / RP45 / S31 / Small ribosomal subunit protein eS25-A / YS23


分子量: 12067.272 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E792
#74: タンパク質 40S ribosomal protein S26-B / Small ribosomal subunit protein eS26-B


分子量: 13480.886 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P39939
#75: タンパク質 40S ribosomal protein S27-A / RP61 / Small ribosomal subunit protein eS27-A / YS20


分子量: 8893.391 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P35997
#76: タンパク質 40S ribosomal protein S28-A / S33 / Small ribosomal subunit protein eS28-A / YS27


分子量: 7605.847 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: Q3E7X9
#77: タンパク質 40S ribosomal protein S29-A / S36 / Small ribosomal subunit protein uS14-A / YS29


分子量: 6675.723 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P41057
#78: タンパク質 40S ribosomal protein S30-A / Small ribosomal subunit protein eS30-A


分子量: 7137.541 Da / 分子数: 2 / 由来タイプ: 天然 / 由来: (天然) Saccharomyces cerevisiae (パン酵母) / 参照: UniProt: P0CX33

-
非ポリマー , 5種, 2586分子

#82: 化合物...
ChemComp-OHX / osmium (III) hexammine / osmium(6+) hexaazanide


分子量: 286.365 Da / 分子数: 1057 / 由来タイプ: 合成 / 式: H12N6Os
#83: 化合物...
ChemComp-MG / MAGNESIUM ION / マグネシウムジカチオン


分子量: 24.305 Da / 分子数: 1509 / 由来タイプ: 合成 / 式: Mg
#84: 化合物 ChemComp-G5B / (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione


分子量: 402.355 Da / 分子数: 2 / 由来タイプ: 合成 / 式: C20H29Cl2NO3
#85: 化合物
ChemComp-ZN / ZINC ION


分子量: 65.409 Da / 分子数: 16 / 由来タイプ: 合成 / 式: Zn
#86: 化合物 ChemComp-GOL / GLYCEROL / GLYCERIN / PROPANE-1,2,3-TRIOL / グリセロ-ル


分子量: 92.094 Da / 分子数: 2 / 由来タイプ: 合成 / 式: C3H8O3

-
実験情報

-
実験

実験手法: X線回折 / 使用した結晶の数: 1

-
試料調製

結晶マシュー密度: 3.19 Å3/Da / 溶媒含有率: 61.38 %
結晶化温度: 277 K / 手法: 蒸気拡散法, ハンギングドロップ法 / pH: 7
詳細: PEG 20K, KSCN, Mg Acetate, Tris-Acetate, Glycerol, Spermidine

-
データ収集

回折平均測定温度: 100 K
放射光源由来: シンクロトロン / サイト: SOLEIL / ビームライン: PROXIMA 1 / 波長: 1 Å
検出器タイプ: DECTRIS PILATUS 6M / 検出器: PIXEL / 日付: 2017年6月20日
放射プロトコル: SINGLE WAVELENGTH / 単色(M)・ラウエ(L): M / 散乱光タイプ: x-ray
放射波長波長: 1 Å / 相対比: 1
反射解像度: 3.1→55 Å / Num. obs: 1332963 / % possible obs: 100 % / 冗長度: 16.4 % / Biso Wilson estimate: 67.044172739 Å2 / CC1/2: 0.992 / Rrim(I) all: 0.422 / Net I/σ(I): 7.65
反射 シェル解像度: 3.1→3.2 Å / Mean I/σ(I) obs: 1.2 / CC1/2: 0.504 / % possible all: 100

-
解析

ソフトウェア
名称バージョン分類
PHENIXdev_2450精密化
PHENIXdev_2450精密化
XDSデータ削減
XSCALEデータスケーリング
PHENIX位相決定
精密化解像度: 3.10000049683→54.7079019237 Å / SU ML: 0.417106379909 / 交差検証法: FREE R-VALUE / σ(F): 1.35503715987 / 位相誤差: 26.3598230588
Rfactor反射数%反射
Rfree0.26447041554 26492 1.98796654405 %
Rwork0.216710978651 --
obs0.217667239898 1332618 99.9821436074 %
溶媒の処理減衰半径: 0.8 Å / VDWプローブ半径: 1.1 Å
原子変位パラメータBiso mean: 60.3351349935 Å2
精密化ステップサイクル: LAST / 解像度: 3.10000049683→54.7079019237 Å
タンパク質核酸リガンド溶媒全体
原子数178049 222470 8976 0 409495
拘束条件
Refine-IDタイプDev ideal数
X-RAY DIFFRACTIONf_bond_d0.0096981057589436900
X-RAY DIFFRACTIONf_angle_d1.35396564812647650
X-RAY DIFFRACTIONf_chiral_restr0.058657314534379249
X-RAY DIFFRACTIONf_plane_restr0.0070226479396841542
X-RAY DIFFRACTIONf_dihedral_angle_d18.4789913846236626
LS精密化 シェル
解像度 (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
3.1-3.13520.3499006469578560.32174528379143259X-RAY DIFFRACTION99.9705402466
3.1352-3.17210.3397385138488880.29434724900943525X-RAY DIFFRACTION99.9864922668
3.1721-3.21080.3262933754688780.27820808606143386X-RAY DIFFRACTION99.9909641276
3.2108-3.25140.3269475334988780.2718374620543496X-RAY DIFFRACTION99.9887334099
3.2514-3.29420.3050602197028860.25821426065543403X-RAY DIFFRACTION99.9841972187
3.2942-3.33930.3055134411318670.25747714921243477X-RAY DIFFRACTION99.9977449543
3.3393-3.3870.2935349055019050.251809926943437X-RAY DIFFRACTION99.995489807
3.387-3.43760.2934523392268470.24978828443443436X-RAY DIFFRACTION99.9954837981
3.4376-3.49130.2831953572888750.23471545513643473X-RAY DIFFRACTION99.9954904171
3.4913-3.54850.2950971855098910.22645826940243449X-RAY DIFFRACTION100
3.5485-3.60970.2739653917158650.21810958844243559X-RAY DIFFRACTION99.9909966688
3.6097-3.67530.2614629492979430.21058203653643331X-RAY DIFFRACTION99.9954828801
3.6753-3.7460.2668081563419330.21336161625743548X-RAY DIFFRACTION99.9977518996
3.746-3.82240.2629180326718580.20870812239743399X-RAY DIFFRACTION100
3.8224-3.90550.2576127067119110.20113162395743484X-RAY DIFFRACTION99.9954951911
3.9055-3.99630.2571056176668710.19869957304343541X-RAY DIFFRACTION100
3.9963-4.09620.253617338048490.19497648617943466X-RAY DIFFRACTION99.9977434787
4.0962-4.2070.2513099525139080.19386101950743487X-RAY DIFFRACTION100
4.207-4.33070.246926335838490.19471880080543562X-RAY DIFFRACTION99.9977483563
4.3307-4.47040.2483476638898930.19060072754443506X-RAY DIFFRACTION100
4.4704-4.63010.2481189133248360.19390839638143625X-RAY DIFFRACTION99.9977508884
4.6301-4.81540.2412971460298950.19095496708443578X-RAY DIFFRACTION100
4.8154-5.03440.2576510089048860.19741970526743548X-RAY DIFFRACTION100
5.0344-5.29960.242773866438730.19538554633243574X-RAY DIFFRACTION100
5.2996-5.63140.2503590428188820.1977282646943636X-RAY DIFFRACTION100
5.6314-6.06570.2417191981598980.20207239300843658X-RAY DIFFRACTION99.9977556837
6.0657-6.67510.254484910458940.21095734272343626X-RAY DIFFRACTION99.997753869
6.6751-7.63880.2625283716998940.22011122290843744X-RAY DIFFRACTION99.9977598064
7.6388-9.61550.2695985666148730.23042323927343853X-RAY DIFFRACTION99.997764214
9.6155-54.71640.2477527514639100.23527623904144060X-RAY DIFFRACTION99.603534962
精密化 TLS

手法: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.1672462668910.0232542765463-0.05786456044070.1127409894050.01241900295080.188191587417-0.007358654566740.0285327570741-0.02808564042550.00682198633932-0.0329444192822-0.02557314867910.0248373523741-0.01578199749070.02157593954720.144568994857-0.00537103831481-0.01035246623290.1409504408570.04842348150860.18035931135368.3133070021-1.5822181696147.8292812118
20.07341808714190.04369512825380.09703008277750.245478606887-0.119972774910.1918546852-0.03747220549070.08597133091950.179836662683-0.04112154275590.05811792313030.216619959653-0.219972700018-0.265489868279-0.07045898581590.3844711165940.23057438809-0.03788317624950.5436515759730.1589301865510.44500241574712.787638699167.104987141626.0491514575
30.2062937580580.0497720153423-0.04814443630740.09407449817960.009101433402320.158044957953-0.0130092733338-0.124980322047-0.06814042840770.062854981463-0.0144278045046-0.1608383041410.03781828269420.1722064315750.02729413892930.2499896909320.0348138868568-0.05884517397830.3892502576960.1053811924820.409749087973114.965002268-7.2928762098182.2979584555
40.1657396458880.0464029569498-0.09356716894390.1142886433030.07504577602330.146542602260.01649005297650.06815219178170.129185490972-0.0999381556479-0.0443226641632-0.119984142666-0.04991617202570.1321324531880.004827997929110.19408938942-0.01214868839970.07577401029170.2675972412790.1115701490960.358710771903123.1645900974.313380233816.5949383945
50.1414088588360.07456109562640.05372452887150.12160762073-0.011151471610.0373239406573-0.04035831657510.0542390977797-0.1423810503780.036386772481-0.0341652313992-0.05034481741750.155872323284-0.103311203896-0.0415488686020.343894107489-0.199263247780.1285374948290.241685466288-0.1320262907270.31340956369233.4439479164-61.112946077937.640178513
60.2614014129480.00997421003712-0.05856695431790.243868703972-0.01821002294520.104910767160.0563383447878-0.114134079275-0.0127866045110.175737948442-0.0573503220591-0.0540935948957-0.030058715319-0.0241295324723-0.01021889858410.225034769483-0.03792376976390.003974457715640.2272421570220.0007001170723040.11134341403157.941997234924.897224821102.680315147
70.008611743959470.0220990285352-0.02987118737350.234929640886-0.01546469910790.103540867497-0.0821307735970.08849827912660.24537306546-0.0763784865323-0.007208690001410.120107656474-0.170709019937-0.0816694325443-0.02608304903360.5332331972290.228875476034-0.07459283845410.3239298148390.1699243290040.55675380601625.999911396693.428608896428.6849843621
80.108981070142-0.007677780989810.02712387446030.266384376654-0.1101034076540.04960753895710.04563790324-0.0771897509541-0.006064215817910.219914154595-0.07073732675960.0327532098916-0.1394983168340.06044382461890.01600864615720.255375492755-0.09783623975610.08637351721060.323081831703-0.0482680943320.194048439148-4.21276219204-12.1139204825106.185779296
90.209786665275-0.04329460221680.03849736254640.555463827595-0.001922128055470.09033927297620.0370971232448-0.01021702420380.1302858429740.09336900118170.02222450128570.0232975970624-0.0217209445822-0.0896105089389-0.01772904995860.1060182728560.0617865240474-0.006755829023570.29410075547-0.007161070138760.2101394611634.7683533581831.413343121177.1960143675
100.324976635291-0.07209192570750.01686926533260.5271654110570.1583259382650.2670956855180.0896935563529-0.02217523841180.0465776400409-0.06159025207270.0321940715655-0.338533590878-0.1213598912510.246938909727-0.1045397552480.214743552703-0.1670030786550.009453597936510.5130192053110.08532835422710.528272223215154.49928455240.21351040453.4050270051
110.00908591700167-0.02919495733530.009324897880560.0850161476817-0.02033983822510.00599048893747-0.02987470237210.111992329843-0.151991930923-0.0645204300973-0.00488367554350.09730688074260.118094515761-0.1316584665130.05040894084950.324694966686-0.2152168110820.02212491283340.664357202642-0.2050613000450.332325794934-11.7354661389-33.078413576318.6597465753
120.2753967943860.1015569618160.01222274221110.2325769655060.03957301959370.5790084942250.04211668469630.1722783872680.0775135572606-0.1155371983030.01934151159820.080923875079-0.107976837259-0.1097983226940.02995863619040.231737666750.0419314662266-0.08301552121550.4749209416050.09274737386650.18130736239510.465674862827.210139289113.1214469247
130.1375138755160.113085542906-0.1125026799370.2257218761160.0196395222250.189203144722-0.1400447242210.2107331701410.118949949502-0.2676234448730.04154677946030.0595494526823-0.1225930622830.0471263651780.01849322643370.7486515110050.145314418959-0.0475282921730.7311063294530.2815248560.40403909256531.252536608678.9819467268-7.80328932735
140.1305265483660.08101939130030.03248316313950.1487082755080.05379910014770.0196060904110.0280288914272-0.04854710568670.0893259216080.04553908627220.00761834063116-0.0888035193536-0.09132341396020.07350827248720.08308650756260.243198801427-0.177611728464-0.06737353959320.2789316272890.002914959722710.28177773459498.896283676555.310472204287.6829119411
150.1612044586580.1165780789340.04683329348640.0964646911979-0.06695334012510.592287025209-0.01996518850470.0398318774696-0.0159885134367-0.022221456621-0.0206223107720.08244553896240.131683684591-0.1816564393890.04335487404790.154877363244-0.07079708989520.01637045479090.435203925226-0.01046718043420.286270910912-26.1689136059-14.229390333164.8619485069
160.140992393599-0.0200592603582-0.01935021473590.04437808751940.05587052566260.06666772001410.00481347015461-0.01415300149640.0634255752168-0.01310397221390.0271753450916-0.0994791370061-0.07557666913750.0873799980755-0.06843886245980.176363454002-0.13918518345-0.03463671686050.3230388648450.0886376977920.355329279198119.29255188832.448754542361.6358720772
170.0617639290953-0.03580016933290.006222326272260.149911076510.04606094379630.0363523284473-0.06447589591240.09792061306440.02099836360920.04144772092980.01475380859070.002395613306050.0957095763577-0.1269943760920.02787473935710.224076466049-0.1531453500030.05043826401590.353344635155-0.1049915655710.2474541920133.50391748145-30.04340264656.9815908728
180.2941781214070.0602925493770.3108374528330.454840888696-0.03632630607290.352766180585-0.0461163458653-0.0922803358050.09202321598250.166742329997-0.01538079319250.107500953754-0.00244253958162-0.178013802992-0.04557218006570.2933660510164.87978444566E-50.05091647762810.1832705266280.07713970886230.29375625263955.6318672605-40.290426078882.7117980229
190.151975290411-0.04144707158150.0008506406218610.19747052805-0.04845095515990.2503722167710.0552013810571-0.03728381570170.05203534639490.0653922520586-0.0483247216346-0.0497642071225-0.09141207523540.0159079324958-0.01545400997510.283382212144-0.03438534333490.04649878227310.182707944546-0.02446520970420.24217045199651.966111621450.044956933489.8837512202
200.233026933984-0.02656228961270.038621330580.2102008258950.05334874275950.0231131697273-0.07668395310140.139576561337-0.13049462937-0.0539355868081-0.0300296797666-0.1077747642660.1761989120420.05681732650670.06714246921270.3614239104390.1489210801730.1395613365120.3647328747190.01093777202510.499643009299121.771257528-57.618132183610.68305918
210.2220401558160.0457662120957-0.160404580330.349928495856-0.249395903750.246753873209-0.02645023550030.1518066705550.0451054153345-0.110423523194-0.0009196561966540.08584433474940.0565394987915-0.1957952579110.01818721792290.1369320268850.0280908663043-0.04314845207460.459155411695-0.01253649606710.252334666434-12.348742918414.251041467447.1868940863
220.2422703330410.1565065867160.02253614288360.15647951195-0.0894917219390.188217643647-0.001473271141510.02650581501680.198229128904-0.02095882565580.00798082773760.138896713529-0.0666439228122-0.1454522823150.0260761562220.2320338852390.151238702797-0.02573286430630.2711623438130.03777767074980.30229301493621.77934178655.101022174650.0627297797
230.328807432549-0.01213772396150.1690067111290.2985627156880.05038451257020.09745501826950.0298602866721-0.0119308931904-0.2383984530630.06441423736890.0106570429748-0.002072672136870.1046601561310.013553972022-0.02398696746480.765242075490.263844102472-0.003570844002640.446907979863-0.01896211866981.08036124685113.653757333-89.438142307542.1290830675
240.0679573108977-0.05765161230510.02293240202480.3956844215380.02595203870510.123535399671-0.01588505215810.122813351784-0.120274746067-0.170732717252-0.07938588033770.1854942748230.0628984430508-0.1835058423860.1054314735480.324089712779-0.05043728700430.07402254150860.336223989452-0.1389785774150.26702583020949.1012646963-45.3291096693-0.238010932668
250.1493472565960.005989454558490.146336893940.4428284211420.05812866078020.1491019214270.04304773392160.34578887043-0.524462618887-0.1409162481220.01668287288670.15755715060.5769173962-0.159830578925-0.1616737287820.725287085341-0.1168381973990.1348987295370.410242748181-0.172398484240.59865856092257.3127180019-81.04615713893.67779465731
260.127149338699-0.07737915731590.06717280738670.3162198177480.1338720178880.147771594017-0.00492922561907-0.004129908523980.03060033217670.020509903782-0.0130223605396-0.2353428334960.01301935072320.09718054289360.03412953351090.2788562758620.121130484183-0.02629417413670.4425568761920.1560551654620.446974739381133.421175092-24.567266301674.0236984286
270.134223372168-0.117353585157-0.01074571641660.123067836003-0.02812937660960.204885180469-0.1127999827-0.178039439035-0.004213310955420.1708957039820.031399650734-0.1379026754560.04619563728880.1413139921380.02720073596870.3434330219-0.0161775618199-0.111933448120.4900957017910.128178564090.26406042974496.8796189217-11.3726596805117.280087559
280.285438605330.04772591600530.1000179497860.01545357278180.007988073104990.0444429288324-0.02984595338420.0195729951309-0.02617534891670.01152081149840.103736584247-0.154825431760.04232178978550.176730359141-0.04954638388610.2814485818190.1519098357830.154150749070.698383297393-0.02353951542890.710296489534172.826690407-27.019007592619.4608862007
290.2487838744470.0682621025839-0.03439567128620.108356434535-0.0839615182270.0803758557980.0395938020853-0.1193296119040.08614908140540.0590120140423-0.0402138389573-0.00857162519974-0.137340484975-0.0187177815476-0.002531613472160.278167305068-0.0775247990691-0.01137512631050.2261612121260.009325616532490.18652144087572.304377914354.36427843178.6424675803
300.3231341124540.114747054166-0.0063122998470.624741911532-0.1057156814870.05482564718920.0337606682968-0.005217585439830.06355270766090.231716574273-0.03262608332880.0581392876352-0.156612058098-0.05374155672510.003820635296530.3565545813170.0542868767434-0.03827360425970.2972267058690.1008813259270.29093801238941.757703089256.440135565363.2039551249
310.2782409789370.03396516308240.09282013084550.3559223577770.09836862719920.05245953693970.006037495977210.2366229642140.0730805578828-0.184265436129-0.0199636683562-0.076799220920.00915586753420.1600031700970.001077630956760.3977357370350.07387904403460.2412416452620.6706040010210.07062838798120.59973012431155.885929675-22.9077245123-8.2381212139
320.7715600246870.09962594802270.1815177423660.561620759395-0.07196582941160.1321829927290.0465962640649-0.229407401591-0.2689672449930.341742780573-0.04126327256610.05877863554010.120626266014-0.0701782255351-0.0339805077980.5849460169370.00771746184840.1782457215440.2518441657040.06545207153140.50189946918973.350344786-71.889471929855.9530421292
330.127132594716-0.02311344422960.06414282291050.200296716837-0.04077510172210.3079376334990.000789569218387-0.154419628228-0.06949541021640.136226483019-0.05308649433710.01913723979480.00157332590639-0.08417909120570.04301782827240.171539857942-0.0614162952520.0002639161483170.2330882115740.005841169848180.14663408395443.00226812640.27378463155497.3811068781
340.122225768029-0.0359468003379-0.06878994403190.3624671080390.161667660710.298049814537-0.00533825444542-0.0685203381302-0.03515551637360.150760624359-0.074271049758-0.07609424737780.06387928529210.03017572526590.07498361902990.155995955104-0.06531468515750.03523291227930.3442887325780.0007538525728680.2180945187419.21773119995-14.263406784383.6902076944
350.273714931002-0.115680947332-0.06203251432920.09317064956020.145388451960.3325149815050.06298777560160.06352660571530.136819069768-0.02481073880660.0180263460746-0.177063417488-0.03599342941570.208338663479-0.04967685634620.225668975570.1461899642670.06926107926810.4636085984970.0909913327550.544324623737141.698687276-27.024547614828.5126867969
360.183223378087-0.0593723325478-0.0697870070150.23734047086-0.02512705848440.143030996668-0.00113030752391-0.04635231753760.02766595208480.237938626877-0.00275500779135-0.28308370257-0.0164751701540.269328580519-0.002165927794450.247130207413-0.00792237438846-0.1058309550150.5299640838580.06003997132130.299276818778128.550467371.035850818894.4215343256
370.251417147522-0.04506534467630.1204146625730.1191412533230.04800949358270.101617922849-0.04116774925850.1654339444690.227398507545-0.0590279627854-0.0677202391136-0.146162635959-0.1254642901980.1444109406070.0296726098570.382005035999-0.161936768956-0.003742528816650.3590824748610.1531527678680.522279112272120.03766730264.078522469255.9276884434
380.3077236636840.0825369824360.06385625243540.3132097549610.1466382919650.1296100474690.0327542864150.008179938319130.1205072332890.0457909851288-0.00808107930842-0.02409576511410.1271676729550.033298285632-0.0267684736130.1984601377560.0336333682777-0.01888989623590.2598584218550.07956674207910.309843354809108.037899105-2.4238276901670.9486718323
390.272597798713-0.12861575158-0.03267542228010.392955191039-0.05010401297910.02135323584480.06741219064660.0299248991349-0.156675451392-0.0175239349918-0.0370321385395-0.1183472522150.09291798594620.0749701039145-0.06239856817960.455631384770.275582651259-0.008328682590710.7424033539910.1979332740240.689145423862149.015689878-61.351387874452.624274954
400.217427804272-0.0074868117091-0.0420112539590.1742286416930.01192703709550.07874677032820.0295767622939-0.0109306656323-0.09922258644260.102869110837-0.0101835741537-0.033287561213-0.00329378032002-0.110369906283-0.02563741503790.2708009841210.035983226968-0.04344319747180.3842996544040.1210691420640.415441452714101.522741753-23.634199050375.7580440703
410.176308541454-0.1497281185920.09164082638410.163283963176-0.08796095449880.05060267531290.108892576446-0.00541607304616-0.113429865311-0.2082206111520.01100761378310.1103210207710.100053865335-0.0720784545056-0.04573010992040.374204124858-0.135890507635-0.05800676244290.734645999936-0.1159923781450.2718248389521.86606609749-17.21106349197.77462546244
420.2868355323540.0480247184589-0.04386918578480.1091418734290.08731841254210.101098846314-0.003456817195130.0737569801802-0.0360464220796-0.03756362908920.0259278139206-0.0504577548174-0.05782719215410.0347830815828-0.03213108960260.479760096587-0.0524457962670.06984991021320.5387393387840.03915303746180.42542120630486.9213992042-5.04732451429-22.1579858093
430.348413697962-0.0924366201287-0.05824927227010.4210294830170.09207381826240.255586408614-0.03178126035840.1847880642340.169908722134-0.1316618925090.010596939010.00215779254186-0.22558059187-0.112948237103-0.001143849271080.4146470512130.00479932837323-0.02638235002450.2435644848570.1266363335090.39459973507272.981866280861.145502818631.9100597039
440.1991678428060.009084397736750.07456171899020.0770555362756-0.04459572807030.2325667068830.02384489976830.119853622575-0.0013301110107-0.0738432186541-0.033501201036-0.21176576422-0.06682641258910.107854745868-0.01306604927480.2291562799310.05496919109850.1684046138460.3053022012560.06879688212310.396429596028124.819567199-13.53741424791.79700399203
450.0809829051951-0.149034251551-0.160577251450.2443493643950.2719772133280.279632704488-0.03500896221030.0822030231457-0.049530997784-0.0372658357835-0.1225914713810.04192705767070.0014063922654-0.03682221588490.1180386542610.7933327697970.05719983999760.02841674536940.6860184807590.2146200664610.35182919426449.027555858840.5876425362-47.6677720892
460.1560901472120.01620789296770.0294347889750.112566011251-0.01098841146090.17726392608-0.04990634249350.05641501653920.00379072510451-0.01653062902860.02165453512010.0154617929092-0.0195910446784-0.142197296056-0.00391855615870.148927401535-0.0165138878003-0.06182006653530.0202507282666-0.003756826424050.276521827854197.330169199-2.93138905131175.136449988
470.04843808140560.06255028934370.0543539992120.0494744348060.07356889139140.122694728551-0.04978351234590.04230076743290.0455933734306-0.03238505897140.111952830965-0.287983170871-0.1394600563840.0802069598457-0.05409662374440.288725735069-0.0733285672206-0.1049877950470.154541371512-0.06511901571480.48635269935264.97969088457.0945139905186.153226157
480.13239136794-0.0328500828249-0.0123749593910.1631473072980.05363418643460.149161622653-0.08378438776260.07192331815740.0131545953932-0.0353715920070.05955806385370.202173184882-0.0349210586584-0.2361927189470.03888806607750.218627204907-0.0222500037261-0.1192706791770.5214976897010.04469022191330.44064378937143.642281381-0.584343857793152.501832114
490.126651429777-0.0561996085371-0.02969040234580.136452123070.008153004479430.09640622107570.04444101458570.00650460248940.08748572719570.0945998669168-0.04070047090540.0514344516825-0.0848401332188-0.184295578265-0.0003904215924190.1716326583120.1000287856580.01645694565770.331939546341-0.047780726280.304867751108152.2197796026.95661641097218.668831315
500.09693353119370.0486840319060.01465019981070.2086000468120.03837983798120.0421198820603-0.04312651957560.0262385963673-0.05236319884950.01997805302390.0299066520168-0.02914023500630.07308759810620.00122971130894-0.04144296410820.243216188272-0.03348441498290.03622498720550.0459074421043-0.0463316172670.343709286051225.720711986-66.4589044167174.150072292
510.0996987671512-0.0184089678840.03854830556510.09632266146060.00278004259060.0652193306706-0.04125932378440.08185281708240.0412840650958-0.09265933603920.03037442166410.050016385923-0.0465791634195-0.0261076139938-0.01416334374960.195266087832-0.0229810931506-0.1309195725030.2264121803640.1047215987320.204618325238198.12760244926.2871402657120.611782889
520.09987849183240.187617336790.01007454358170.4355480311840.1362228313310.146966873017-0.06671993290370.03430354144840.0198898916348-0.06440976471970.0651899543673-0.10996983632-0.08665101862210.0487510682052-0.03339299706620.432264930325-0.10128951195-0.1500832448430.1134376463810.01909936748110.38559714544255.37181908284.867319885187.258229628
530.225582099092-0.0282736410039-0.1493348203970.1713818248770.1825360397050.393439038914-0.07232311543220.28085286477-0.0746878471726-0.1199131738090.0165073000424-0.0319125344966-0.1055991760480.003296026349130.04452299387090.258727279365-0.1549229896470.07739483544020.356710800791-0.0643982213990.271310699271252.916850474-16.9147594225101.143613332
540.4672663570420.190567440126-0.2016904039950.421997770581-0.1389698802970.277575900038-0.008474136846850.09567449412670.142516975369-0.1207823672550.0612765972179-0.0341598932714-0.092834235890.02263331994460.1051325467450.180793847995-0.119463145633-0.0107183917560.1058983274460.03984084636810.235636130793256.21119427224.9280249843133.366370125
550.293850927848-0.024025531081-0.05672165736670.36851375876-0.001138266681160.110149096492-0.03232763250750.01304667805770.1005451310250.05965900875890.01816000819370.176973096413-0.100285251549-0.157321638116-0.04807011186760.3967598765660.3030799862130.003841033070280.56778628639-0.05111099109150.707051080943118.30835257548.8782608438191.870678576
560.0882110420859-0.0395913247323-0.01728276051930.114958765494-0.07769521774550.209712435982-0.007124556787-0.0160378799907-0.07137141738080.02562797503590.0667130878968-0.1418021353490.09876245722660.08847539654080.05018891983820.2085529030320.0606478109518-0.03722323572590.128119958281-0.03491170736560.426522854079277.321272757-44.8318827827183.571667792
570.00155578638499-0.00173150466946-0.005047831241510.2132700618880.04546469413910.1711106805590.0138212094153-0.0410409402622-0.01673533462290.1510998643390.0499084922663-0.2634687789550.004996240045070.1030345482340.2663195649710.2813340205330.0146240602986-0.2718840426120.135037403203-0.04813152374050.492879866872264.35152269316.5043842171197.057779309
580.4349044372860.01840238107850.02482469489040.12137069336-0.1098198394880.5371040102580.0807946048524-0.1427378573140.0445395368090.2165562450660.00987601179549-0.1184481871010.0382303330726-0.0432025480074-0.07824477111590.497804921073-0.0171034935115-0.1417385080810.146558545231-0.01461004335430.446168626463256.17663460769.3960858849223.636387433
590.192418917785-0.1172891761280.08259464810030.153361942672-0.07445182900090.0790211785039-0.01538254853040.0524076934220.142837310297-0.0328708754209-0.01089399603280.0506044108842-0.134385580072-0.08941142885610.03673815204080.362059244180.153725830016-0.1459503365770.381283960610.1296914563580.418048332808165.81708147259.9142981394146.074976454
600.2280021869480.03110126241370.05805392679250.173391026391-0.1627531480390.459043064863-0.06541737225040.117251595915-0.0823781149708-0.08462839910240.0825108058432-0.005810006493550.13293498063-0.03338420159450.03152550267770.139227311799-0.04935542207730.08027964787330.187049603381-0.08354918301120.276685860295283.117194144-24.7093467925136.042050958
610.00972836418214-0.001681466266250.02088079455470.0125961280436-0.006202773164670.0410090380981-0.02955891997550.03751050960910.06326363356140.02871669916490.01081344170730.0769060750383-0.077198042041-0.0309868010052-0.05625885654220.2195375004320.1864893268-0.08135286280540.3565234676530.01928590964240.429332746315149.26318122837.7507936864175.271897438
620.3424900064140.072713146441-0.02543080994210.2011341447120.006692132485740.24089098828-0.04805809020270.0790653664769-0.06252364520450.06970290404480.0506756484686-0.129290692080.07202217117110.0631111187031-0.008871565059020.154832746024-0.04496885272470.0137377069930.082927538299-0.05206935248450.294176789969254.16664046-37.6870870488149.93655906
630.642523752127-0.2193761054330.3235588565650.875257546495-0.02979452944850.565435471008-0.05725570767130.2947102630320.0413458287817-0.326139163170.0377312397268-0.237824160361-0.01412475966790.250081510176-0.08758421804040.218422268811-0.1418303256280.02464902016350.242330546527-0.06003759355330.300434733558196.634848393-39.975270508136.634254748
640.1149012032670.01331360154650.05325666383310.02669080795810.006206137500780.0352612106231-0.0239395174630.1024234906820.0488130146465-0.01438676927190.04310175836470.0764500773056-0.0240301976049-0.00366545508436-0.03571410921150.402575195082-0.0469736946779-0.08613134030590.1849726164870.1285097142310.342280562736209.97933462549.6236507634132.628423178
650.358037895012-0.0342932215110.01405565486320.3216238212010.08793647014950.0247439759488-0.0115106475517-0.18718852913-0.02283622746090.19703918686-0.000124246688720.06176655993310.1351515927590.02339495493390.02578474204860.235241020215-0.2002332312470.01746028078370.3270642486890.04512067258290.391361030338147.191465776-56.5697761756220.914313674
660.1279555366150.070343424891-0.04634590183590.0973877725866-0.03154364588190.119446853692-0.03863405394610.0457848585894-0.005404487017470.03609828242840.022472678176-0.0537058966678-0.05730041327590.04779531304020.02356530242820.144403539309-0.0520376488362-0.05049694359670.133366976798-0.02789985711380.327847817187277.398096193.80841386325157.690386774
670.272516099937-0.194381171043-0.06791192431310.1416268395750.08167095768020.11123736433-0.006719963351830.02010186820470.114982535644-0.07411834329320.00322614244878-0.122180698196-0.1358672762660.01862053878840.001934540445010.288073106967-0.0685309973589-0.06432766818950.1147594584690.01139791055680.424586028175248.94245153648.2105293172164.625473504
680.2284297850190.113769191535-0.03034052799350.2561676089230.0217758147430.0140433507142-0.01234225512350.088588164424-0.1444678284680.01947631814650.009493318516540.08111626908020.0543443220941-0.05568983143340.04483295908860.541444569368-0.291611219567-0.1231430695160.481249341494-0.02056479896870.771082221091143.67786274-85.1260673968187.242226051
690.034177842517-0.108328737651-0.01449472051560.381340525872-0.01694612346280.0947013275079-0.0727563245314-0.0437763722407-0.04746699209990.100945049852-0.0200568669636-0.09801480070220.1002298503540.07453715552150.02031565465610.245945911905-0.0176506552155-0.03963439858780.100599867320.07399182989120.251603360244221.37985363-51.7322271696215.280538609
70-0.000820098737413-0.01880957403730.02589979038720.0728392207791-0.125728256960.194407656425-0.046688695596-0.0763629283736-0.1905942102220.03393898358780.073133542252-0.06614338408670.2098687392980.0230636147861-0.0405350653890.492489196394-0.0356150150372-0.01496547967570.1531182278450.07299302988640.511541949134212.274054406-93.5938901352219.75425721
710.09758519113550.0284828923670.06061870085530.32150782767-0.1466245190660.122699995243-0.0163011543534-0.00604825128120.0116996550174-0.00226885173766-0.02434291165960.232420565253-0.0403299164874-0.1156887307670.05951575707420.208309811396-0.0838046328358-0.1029996345470.499377957444-0.03948757667790.424215773237125.555578902-16.219642125164.021159857
720.1195071184330.02188082351240.01889127457850.09988003289620.1329889608740.200481590621-0.03237191390720.139460240051-0.0457567931569-0.07657230448460.01080436235450.1005520317310.0261477026063-0.2724435406380.03133857360310.367025944637-0.0860946660466-0.2081425056870.4964591843760.01759028363240.360292901633152.872481048-4.29530357954114.389469809
730.4394399341430.0406191577759-0.005377001827590.2093602126930.02334259903010.0601656180033-0.02827367906020.219129106317-0.02476550016620.00144482666845-0.05167416856870.2448829115310.0177873787738-0.170429817910.04689718162040.302464683723-0.02864682104040.1591860927761.05046034820.04345597869430.75224759222999.6085531235-18.0305161971226.277751823
740.12947751118-0.06431449727390.02668578675610.1538486160190.01180040150480.00915932654489-0.04147481217480.03557368376320.0760565002053-0.06597724119250.0276548575838-0.0037163747102-0.0823766409895-0.0682520428502-0.008256389523740.2685213597170.0606949853034-0.1116884700960.2207788866220.1240990524980.320136795075193.42142178955.3873873744148.48914038
750.149385022596-0.0496588901668-0.09631124703470.09837077471060.1406291353580.207166020516-0.03551448325090.08960629483980.10082790907-0.1790361791630.00560481450537-0.0108120343679-0.2114573141010.05426539580090.1283430471930.449093031504-0.0680488418114-0.2312599864540.2270875712730.02266005613220.361156733143226.92229052752.7695456195156.25664692
760.521414094283-0.120326709081-0.0591274453920.307048730345-0.03029180756260.0135968495187-0.0227267529479-0.261171177453-0.007563293325890.159333015918-0.0424676998840.08268866567650.02330671453480.002545070538880.0328996898810.3361355861720.01087447848490.1899706437610.780712575163-0.0007075210952450.446333461487122.965278497-18.4186872748249.158557143
770.7499104725930.0188647659006-0.03356809603991.079336167820.3639163796140.402478112263-0.03550816459220.240321810858-0.159750626607-0.379997775380.1114201775650.0844098306632-0.0106533721572-0.0250226165875-0.04926356619050.380945381505-0.145079105301-0.01996047194620.236675920828-0.03866281713730.353524579965181.748875659-71.3643124119165.280624724
780.299844104904-0.04727920362340.08619878574710.1726919729620.04808965925370.293477894008-0.07335836408240.199905243068-0.0472882066053-0.126138089109-0.014331312282-0.0457199175101-0.0233415610065-0.04563383217980.07807798720630.222840477454-0.0702617585114-0.02055140381780.2915229234230.02023187501430.207378858604210.696955085-0.176372316929121.199612596
790.612264922632-0.421326461876-0.1251895518920.600383514184-0.1170580411470.4833864932390.03609960732010.178547860291-0.0499544197425-0.1494753859890.03233881633340.2266569015460.111168931839-0.0997476613936-0.06284901985020.252503750639-0.1153037861680.03240899029210.258751396154-0.0300789818340.246039129669244.68747943-19.4595426029125.987435859
800.247338071732-0.0801206274578-0.2119843146920.123052607334-0.09178720246450.431152871538-0.00599541957708-0.0660213098780.0692099039152-0.01538369950410.1149695408720.189252624555-0.0648347860274-0.205729919296-0.1152130908590.200702768443-0.06037426643890.01092163369240.652543052968-0.0222304564860.540459320829127.645464279-21.0665141781210.039994651
810.1270287805910.002658994840180.01000074715990.002501153083560.01259639886550.0572910889527-0.01629338670840.06037762958260.089135257263-0.05242314047340.03493949351320.069690963148-0.0112616002644-0.1407550285120.05942069104620.2983484609760.0132624530183-0.1923664781890.5604309119230.0763104192330.438039926143128.65929908510.0665585112144.286784299
820.309737213080.139726245203-0.03070598881290.204884369312-0.1315374719390.170388254367-0.10185834122-0.1693596277910.1244597177080.09732289934230.02350569226710.0646040727614-0.0780276262536-0.02543180811860.04142556923780.5206671288020.25388367335-0.09904228745490.379582748957-0.03433072426650.56684863268153.92968005468.682669964182.310363965
830.1347980046880.0228201376741-0.07022221070560.4177161623210.08319601231270.118225112890.05626254321030.1684512023060.1111755738-0.136270206499-0.02143103079760.0778245801215-0.0548862992411-0.1665164594840.006551266243610.2182934572070.0387190406528-0.09940025529250.3744105140050.05027750828960.404806009121153.5147089122.64343815825162.021387654
840.2744876275090.140039326517-0.08314014456120.321833045698-0.0442334366890.02510805223910.0187317005445-0.0869775827303-0.0534769084360.0279176014137-0.01702390082950.1549972939040.0307736241494-0.0582303396323-0.02248212234190.350208960388-0.2740755586860.003689652054110.815385389126-0.04010735612640.741726409576110.730375533-52.3912264573186.619629759
850.130130956314-0.0410802224774-0.08315857178910.317797538764-0.06737878981520.08154992201280.0611157059165-0.101265177441-0.00530801806861-0.126703018299-0.02076661015040.07776598667220.03192986795040.041386907931-0.03079485700740.251137884833-0.12908742257-0.05907197584360.4455751305350.01287646195950.341108484136156.013502973-18.7753293551154.854918348
860.2171579086680.0168988507032-0.1442163737170.2100191599620.08212803008340.137718114750.0530313343592-0.054109759787-0.001013381300360.1066902253490.0245720841477-0.175787330660.03959710939560.0546311086172-0.05702016232840.297881811564-0.00556102397355-0.1100161337790.1083364669360.01125589818620.348999063144268.456813722-28.6336562299197.898108783
870.353505221537-0.0705907793133-0.05480489897340.328392701773-0.02153245442840.1351413753730.06413547913820.119302797785-0.109314714034-0.0483036561589-0.009115846562010.0640474621145-0.03235100143970.0618104924001-0.0610676461430.469768536962-0.00482706597853-0.01474670006460.3516762135350.0006303160822670.334279751893193.056699894-9.55547903288247.331901811
880.1782302693890.0702449875842-0.02270345059570.6381594387020.1165739487140.0889105266986-0.025308879825-0.05107105176490.1644197748010.1488960411130.0339778996751-0.0332485331708-0.03547218457290.0182487904901-0.05656291006910.3966071612990.11119773399-0.08007423593680.1549814996-0.03840578661590.396770359909204.51647493759.0546529786194.121959316
890.335991418638-0.0503809739327-0.006049200957090.3052700801610.05414416899480.28463720757-0.0815299777704-0.0768943141715-0.04382956607640.1643924325790.04226954133370.3092306126890.013291765903-0.2542597657070.01386056793160.255970743155-0.01159271476290.05001777216640.349626812553-0.003907817182660.380245770385151.682281526-11.8131309803232.523221516
900.0610511378072-0.00939179149216-0.06260404929080.112124381728-0.1658332389460.311462130260.0147037107252-0.0686157497709-0.07603553176650.05846025929630.07129485682740.0847228664080.03643276720780.15191476777-0.03267738463830.83949819782-0.22226457723-0.06423701405840.53200851383-0.04753425898110.56233981702244.23652236339.4118083125258.336306536
910.208411027796-0.129845377265-0.03119937527750.255305475332-0.09124274894450.2091071839040.06352642188960.288822793169-0.0178321724077-0.166287868318-0.12395428991-0.129011492510.0206199843084-0.0643670261450.06217286272590.4376702565520.1357971877720.07972275198250.5997883024160.04451744675530.31251917637282.1458501532-19.2397413278-51.7195826208
920.354603613950.00334212117366-0.2065382081120.01567390570750.03612374957320.2134837262970.0777667623957-0.05190797832710.0585629051667-0.00157205265198-0.0860018000746-0.127164585782-0.2056763374890.14002707337-0.04874786870270.8547786507030.2216974689520.4212349207090.9600483271570.4228360941490.84633110257126.0162336418.49695162784-92.0764764692
930.209473097885-0.2054033141520.05222251749420.200210896782-0.05477819973780.093735271849-0.00165376091152-0.1277634167930.2447454547430.041174617615-0.0574008224409-0.314581649231-0.2153261278550.2479015048170.05914515241920.672886468715-0.2777896075220.1241516979610.7630145434390.1548487261141.43577043211144.78709067928.0975234734-24.870780202
940.261805954519-0.007078041900320.01334977825120.06098789749420.05010663465570.104313171597-0.1113440488650.2824883050680.0623693537209-0.2399455699630.037704941841-0.0815640276689-0.0712551058631-0.004017627952950.02778336431240.8904305953350.2368367360010.1755903288130.9212336146080.1850869480280.3827580201991.6981911061-9.28856293287-87.7406290325
950.197590625170.1358447480050.02958544267270.395698419327-0.0803799766040.0497949323023-0.05618647847110.177261848839-0.0259758133833-0.2662432704920.0308273769466-0.0760448456020.0580638826071-0.111701011550.02610065242420.8489499848570.3048105750990.08771824762131.046587253340.2128775102760.43658647202760.90071298629.6011979281-91.0663433366
960.33900251044-0.02086055463980.007127278019570.3117291939020.04743815669940.110746511092-0.01828283060030.227513994051-0.0714906832185-0.353433826649-0.00434962093095-0.1220075702930.1172122540410.0346365820942-0.01454484389420.7995846458210.01680920147890.09886292137770.70446409329-0.3058589982370.56009525799882.8563850409-80.7900104018-67.7749994035
970.338271572863-0.04743819935970.05900085339080.1562277832070.1828930356570.2529772176330.03686607333780.07693283211430.210347461736-0.07240115800540.0451619213138-0.201943642413-0.0823810149230.097164490995-0.08259064215310.783170158576-0.002558381216990.08001326448490.7189789319340.3951541372981.16855840633101.63570293377.5164158603-61.3429487111
980.1455428166710.02733424438050.07900488533480.211300967428-0.06486409029960.07527786740330.1069255032390.042841090893-0.242455271831-0.0242064918715-0.1010547046770.1045700933450.27733891349-0.0830191896563-0.02906528300760.749227908171-0.2318137313710.138597738050.571863556372-0.3303092614840.70964235499952.9624339336-97.8260161899-22.1072516914
990.06934208001540.0338247850884-0.06853028310670.1353019248170.043844084410.115989064135-0.101975733047-0.00459541068457-0.2008504315690.0146415128259-0.0303025867226-0.2019514756150.2080052436410.3217055314170.02028549882210.8214680578290.4033892961420.3961860466751.069173824710.1862175194210.8247149075149.832525722-47.6541070738-75.1888684077
1000.2361621415360.0702752490855-0.00645540637550.3723110013240.1014676745770.3069447631480.009330805286730.0518551960365-0.209331919132-0.0391657616965-0.0995151031965-0.1076334104890.2315053536130.0972992515970.07816089582950.4972401643570.1033975987460.1556045847620.341197605202-0.05726143257740.58356089371798.6139182356-88.7137766106-16.3256794353
1010.148400873529-0.115333806077-0.1531185288490.5844014065310.01368046744050.181972245378-0.06601966177530.239242801355-0.0520644952052-0.280415339333-0.007492291205520.141504270865-0.0315448742513-0.2131430731410.06326277629151.011036995510.124800422698-0.01622825348741.08013914987-0.1227428516220.34639292859862.9107799833-41.1748064201-87.654828278
1020.5404954809070.117565993630.2130825810210.4945188256680.103307823260.0908435426694-0.06829349573720.101797710387-0.0622715702909-0.119910209777-0.02644894841230.139133906285-0.0232662016182-0.06974068686140.0724823584150.8038518764320.150278348941-0.03477231947711.106682077550.1711663586960.52395981289927.373375219733.3924404254-83.182991528
1030.0818502305740.06612014232640.04831730206370.799472576257-0.2615624197030.5096129014670.029581414465-0.0629528530245-0.00145498416952-0.0486282729246-0.131449047844-0.4404240683090.1645410877360.2928020785720.06593380792620.3721984825160.06354350286060.1515585760330.517714870254-0.03355837012340.569548956452111.789222938-66.7347593599-35.3051242375
1040.1529363615710.157013333361-0.02058229158360.1856297291950.07863342474480.40860745063-0.07045523512130.0249305649544-0.0202091463196-0.1078223686830.0224683142724-0.003052978094990.108021745811-0.03055658999690.0212616354761.23873616873-0.0833081775947-0.1295782546541.50019888576-0.02945191367731.32088254734-5.5262703322225.8492532747-81.0385403959
1050.303699866185-0.0294228770180.007162916278550.0799987828013-0.04995257925810.08891058755690.09951088538380.0443835115298-0.0228757940458-0.118449549675-0.100244503153-0.2663222279330.02661172785530.2999147397290.005814487524130.3588309180930.08738794373330.1487095569010.6087416572160.2512939791460.734135617286139.648465817-29.7549740678-39.2807982306
1060.001219091161410.005084413287420.003804832709040.07327432915780.02526040211470.01290449167440.0569131049808-0.07012952168650.319373639478-0.05007585999810.0166450988868-0.288654222058-0.3658026515590.0753820840087-0.06763318005171.02853165492-0.1656931692630.01604941408850.4801188120420.2104264445361.24096248227121.65047313239.9442755783-26.3190773257
1070.392292987958-0.02727172116410.09677004680770.604838296076-0.1214486491260.04581093603940.0239868012248-0.02794373673140.1040929274860.0317438435182-0.04835535329240.1642394621160.0102236699922-0.03616450757930.01932236610380.8791229055890.2793896484730.1369391074820.7495311189710.1785679968160.4529393205828.915379147570.4990028885-42.8208361267
1080.06131132840550.0930953537438-0.03008622303810.275025652647-0.09585180484120.03465265556030.145510348070.05587778846910.0266384341598-0.00276339372529-0.0400418354194-0.1856301911180.108009599424-0.02064494570220.02151740589350.8360225395650.2401862048310.1903068479530.7670284782090.4798356799340.92102738282387.76975039877.5756671221-85.3177342518
1090.181699166128-0.09702749258670.02391058164620.08113016190280.01547200002140.0274478143958-0.01628039105880.0478886988984-0.0534131736232-0.127113210363-0.0949497899972-0.127961364077-0.1330857152650.04121990228960.05541238847380.8380684127450.3304004048930.2771362802330.8960249277180.459245610430.852458966813114.56590510930.6256416274-95.2006925378
1100.430626404663-0.03271434624440.08404335165280.1867825260320.03932522931830.0269379797213-0.0611183594509-0.02353747577910.384104539713-0.0193430084687-0.0111539661677-0.154548975563-0.2803811457580.02623859568030.06697508271661.102792419050.2021097055320.1016869374130.623277711060.2084293814990.69465385540956.303713250490.6189171496-41.0156491617
1110.0632362269997-0.10929236130.0644987008880.348371074225-0.03729193268290.1159910128010.05476423066030.04876840768830.07302853755210.0526159645237-0.0398638661873-0.106861603017-0.101115343273-0.02812062173490.02511585744270.9434457643940.2811379038890.2399312652030.7378774486170.4373447796510.84777571435364.125357857995.5831281919-73.6213400135
1120.1041924183580.0871380665299-0.0761444759210.170043328097-0.09616837689710.306491834347-0.02041102763790.2671220999390.0489838374933-0.374445981761-0.1055638828330.06113610555810.00583677928676-0.1000497640350.1153960369791.009952770840.3575057812160.06954750698391.042630774350.3373931243650.58989355471959.399952476456.1046147241-99.2747051917
1130.0385942801035-0.02883776928180.06706598474650.0449103493491-0.04207979375840.118932348974-0.08355497837320.153962737209-0.047588205027-0.1503003176820.0285068923211-0.1514340970410.03453788024640.05154770870110.06133481861750.9640260792980.2844118900060.3887849314241.027102122520.2117256016550.622140725928117.549800558-11.7299294257-93.6813624547
1140.0888314050144-0.0466677064158-0.02958215510690.05597581178080.02066908117010.0515109526468-0.01587342319280.1571868980010.0230244226564-0.0991281671089-0.0556211295274-0.06022208746090.0543053091746-0.1195605889970.004693102055850.5682084203710.1221367644380.2835656993970.7219015105810.03058695737790.448281962839114.584275246-32.8616562316-72.9439624198
1150.268900359442-0.1306558333170.005809440628790.260154536585-0.03278429675180.09760699519060.0532128795242-0.0498408153306-0.0445111103058-0.18228439520.0180378819335-0.03335379659860.0537445802119-0.0323469817563-0.06960158569130.3365532911020.04683701192890.04988080095950.4834605804220.02861553030220.30216939636164.1971173228-21.0097483482-44.9444850562
1160.18411850273-0.0004174380299220.1081696052950.213548161887-0.00919093641310.106490227291-0.008924694641360.259712355925-0.140556879619-0.2531672283120.1093602124940.1760951511240.0759809880472-0.058376937052-0.0802470700660.806637960607-0.0825471415328-0.1388863534230.977188469703-0.2909042763540.64324943797144.7795791937-76.6012158243-67.7893701095
1170.0524391915360.04500962208270.05441230934310.1342274257210.0873273293460.0735458386116-0.00280266815399-0.1072052394580.07057317678880.0230744971036-0.102896276678-0.029740628249-0.0337989962120.06429729290380.07160257932291.25369413137-0.0658265114777-0.01941915508920.9002904999970.3016663075861.3835595600890.2629854253102.355255078-50.2473663461
1180.25677117172-0.252843730592-0.1233691326890.24969733270.1082325123840.3577236622860.05952543254270.1181409882450.38244006067-0.2473000635460.0710927985859-0.259421149699-0.3573713725770.209054514686-0.07193045104080.798866638884-0.09868349419990.1721647571110.5637114900830.309081911110.949816793976117.81733257123.2785406586-43.4237794739
1190.0254295075103-0.077890225930.0115581281660.4407668441630.1650120955460.20370230285-0.00379971133760.0553885856946-0.0248743449560.06534753132180.020249977952-0.217251631853-0.006069747497080.1793602163270.02780684515920.667470902078-0.01073149855510.3300337278770.8979964060720.2742505472680.843346905675152.03653029-17.0859440801-57.7323474915
1200.228448687851-0.00422346847780.04583695492060.00205872185823-0.002052408485110.00973837204648-0.00545641115508-0.08953369161010.01134967929220.1058313618880.0373637557803-0.146531246121-0.02206738856910.12111850599-0.02328524729450.8118795008090.2167213300110.009868216865531.090397326430.420615004461.48974899929117.79178141257.2595455637-58.4826543607
1210.168633405716-0.03658866798060.06683743270580.173902115723-0.06514326979820.256651873709-0.0834346713590.03997451230510.0327452541649-0.1040308033490.031191790613-0.0265696330199-0.0217306109275-0.1108776092550.01897898515250.7495227324390.2024877039770.08243971650630.8336159911580.2842124052870.45100810061548.817064253448.0126588255-72.9374779015
1220.185317449228-0.01145874745980.07931218766640.3217078298440.2572418328620.311607510741-0.03575862569090.2123232688280.0352457542852-0.2683105145440.0762020873036-0.0466895924071-0.04816970591250.050737532303-0.03357198405880.6281319085690.187501892503-0.04530158588330.8851167844960.05980338247640.51161556817749.7218016678-12.438459288-73.5628198879
1230.0887915641221-0.0487671292942-0.06883805515390.160517764655-0.04616912817110.105363572833-0.02955299843940.0164610556431-0.0431942887488-0.0887613854939-0.001138264097750.125301485059-0.0338015362295-0.04242840592250.006835035524580.8918103599160.0655691916133-0.01227771706141.34700346169-0.01996493795161.06589226552.6698043656543.2012316586-60.5594627603
1240.057849480983-0.03680706711290.002459281826790.4642389225820.3122086051250.380666758611-0.02736313740160.1154289344080.0426840673645-0.2058497992080.0344410691791-0.2848753230950.08740881542110.2568955850630.1772443993590.8986634836050.3066719307220.3654768898091.0597910310.5240154269470.938015799178106.45069002758.1961283241-117.10417879
1250.2769177198620.0562425732193-0.091980286910.0217648341073-0.06233412877010.199109112891-0.0187363908568-0.1405595696760.0527432426480.174947169527-0.07180962261730.171011303548-0.12358303191-0.1303200276470.01897543727150.969138311843-0.2473151485450.33266250340.551887302468-0.1781028522790.479395654497169.6020064771.46519573345324.665898132
1260.3531187301880.226707672878-0.1122080831530.4269705977150.1232106913160.3050758120730.02004180022690.04541726636260.143729904834-0.0673857928777-0.08429863981480.308108905715-0.169055095984-0.2913879607730.06636785498990.4621472847150.1993715988850.1375368433340.504086727438-0.1331078862630.530531492063138.02069248325.3847895417263.024583115
1270.328000322914-0.009207119235890.04822901643650.09028513323450.021552075140.08556963164510.0432903656249-0.129936550280.08930299850770.175432781979-0.0145986635914-0.0170698752279-0.1675834860920.0819415337402-0.01882112144550.794767946817-0.211083989373-0.05454211494550.331715724691-0.004058221005410.274698948032201.461567321-17.1693723388312.031976296
1280.379592791856-0.0712748329931-0.1061701865750.272848118016-0.09491510845110.319714777551-0.254618781923-0.204600626371-0.2424857590670.111608274715-0.00289521226941-0.1730187454190.2530533588860.2532937524790.235953446250.7266954965660.06684514859620.06022785209890.5136256534320.06500182834550.775993161864232.78788452622.9506794911313.37448478
1290.277890432970.0757122591947-0.1823152828340.400326789096-0.2459662945230.2181662297540.0512494485367-0.217646594449-0.1025808304580.466006431907-0.01552537373580.052096095173-0.03026191369990.000992175202237-0.01692150455850.772847484265-0.0953016451449-0.05245895951410.2513126761390.1355322357020.421474519413201.955676179-87.8805407785287.285527221
1300.499068138945-0.139117770751-0.09957480603380.163601604276-0.1452318804360.2902740957170.1171293263330.2479102256860.3580031410160.05775258461280.07455181417660.2753458210310.0351284471503-0.27883935082-0.1451577260550.50293802928-0.1110901243720.05364387629410.6084181212440.1431707875831.10592889692188.84704124669.9830170135287.51473302
1310.377044701918-0.0786030965126-0.04033855407210.296668167094-0.002042121967490.2178346253530.0806436791610.00482155381839-0.2078680096260.120456263947-0.0733851999466-0.1602839901960.248553535150.0302170955720.0359047428250.6292162647880.0898702586634-0.04657484802520.1916054264140.006044095789820.63429131563221.868739411-103.52251775234.348140887
1320.250514760541-0.259787012396-0.04938635560130.306112754836-0.02367880718980.166965251724-0.06877272168470.0242900717634-0.2539657716060.08679318812640.03853959813010.3286549437850.210558922477-0.3417363377690.01095415996250.751210901763-0.3599068971180.2171745661450.8523503013140.04796639159490.580708189477140.130517343-52.8009149841310.825332315
1330.2160937916450.125507439690.002371046161650.277925939356-0.009820842166580.192002506157-0.01540426386150.0467098937756-0.180190361701-0.0612023241134-0.008363722639360.208060976970.20074459733-0.2215403834010.04722949145510.462945418427-0.16413025289-0.04405936157850.238320278582-0.04885949337720.575814340221175.380565343-92.1609380707240.142957718
1340.2743377904740.0520689048169-0.0983972026280.401060092441-0.01240633692970.289223491949-0.056590475254-0.2221786778-0.1014171240640.2548454792220.0310761084265-0.1730076071790.199321987350.0267507583230.03117650506380.937582371688-0.0592586191784-0.267513532390.4040778047190.08739905742890.410464273073227.800842866-50.2563201037304.303357686
1350.2781112869970.00559181267390.06682468346750.2253796165010.08660042261830.2140800744250.008357292762420.039549514066-0.1182971312220.03161108192010.06170519343350.2197008347910.117205164236-0.126515136206-0.01848062148450.452761690244-0.2056558070020.0830564278990.2906825311520.0427702525160.476102678045168.539787222-71.4300131076262.343300338
1360.196875599299-0.1743588088020.03099084069330.155851894888-0.000159650806350.3883269367650.102343921645-0.01498722318810.006923641893290.1328973567230.0854349585205-0.04060703772370.105238382101-0.000390398824559-0.1334261521561.452356207260.2853586725460.1645611603141.771629847450.2944649582481.99779277469297.77472479619.6735147781295.337527921
1370.2648189295460.0614133198134-0.04846156194960.2404505003850.007520747444130.1342687728170.0721760546348-0.207364400191-0.01837048628980.0918989579327-0.0495518191830.152666333670.0442167181196-0.234020884338-0.02129530255410.395957787207-0.09833477879390.1082332384660.477606025974-0.01836670027250.443954426787143.317509543-33.288785277274.083580501
1380.221990105638-0.1309526975040.04091296397670.1745144529380.0005212851701740.0677188806003-0.0862791792658-0.07255749188580.4087553132120.0439389612742-0.0126635701342-0.0212778569377-0.172757619155-0.03446255768140.1046127128420.6924179791720.09894953467160.03550634677990.34075810288-0.05993522974780.574731240949161.03524445737.1083315702260.195475736
1390.1945254275760.0751752744171-0.1408254575460.217426456576-0.1950815546370.21247754576-0.07556598190570.1882452423020.142670176568-0.200947478046-0.173527342728-0.1910710559750.1574668322820.1198177807220.2052356147010.71475805769-0.2355216241740.2620746810120.654515258679-0.05030692236340.855260900053257.94968260159.7768685182258.257576808
1400.344879215426-0.138237525955-0.1334035652220.386417257482-0.03158957157070.0727575735687-0.0504054217383-0.1266325134660.2899092824260.1950645495260.1620322418550.211692660544-0.05309920610210.0143887583927-0.0342600745490.75703360091-0.07891999441230.1717433569540.359746473761-0.1903320666130.862274758058206.11585004471.0113800942309.183495381
1410.1208491832610.0486296322987-0.004874277813910.145925509958-0.06198513447880.0547609401468-0.0462949306793-0.0964542356251-0.0557718469790.230707854989-0.1425364084970.271056339845-0.0830038233187-0.1589555554040.1596466305910.889762915755-0.1709128284240.2342719569770.64368512294-0.2772799497160.606284801393181.84352482525.5231700134325.863738683
1420.1802572471230.232634519940.008271884955080.2988756645260.0201126970220.259686182903-0.1070269073270.3087527177550.294712451344-0.1807441425670.1134125927430.239618922422-0.00827227266877-0.159930931159-0.03421608403070.613827763659-0.3205968466630.03754193589040.6456679024660.1926672675910.802832534711230.87995150580.9064561082259.998719003
1430.2089739274730.0977740964830.0100128162440.286521709056-0.07748351489560.2353169747710.0104097044821-0.06775139119870.4200877104580.06757713283090.0693777089240.0712869358277-0.21849230403-0.0391803464147-0.051704987580.643447206893-0.08621493790510.05994807812520.362285864006-0.1130436633311.00263414194227.9711557187.7137818014293.182491642
1440.479454967494-0.1194852011140.1337411197930.263279442105-0.122687666590.0713639341808-0.0466505564521-0.11545648606-0.0155709889260.0885361836794-0.106277751219-0.2124300144160.1277922442760.2283283485020.07755028468020.906916163130.3133674817520.1426574379130.9892475281650.2509438111651.22361365294264.81800665227.066436671301.257559953
1450.573553317794-0.0865685205678-0.05291912202090.490592940669-0.06215370069760.314625139364-0.11523680104-0.3026779411210.01032679734290.292559563488-0.00112027821964-0.228291608587-0.1334464501010.2030271821160.1204788500660.809742747439-0.0384212684228-0.0557271659660.64975971317-0.04968791471260.685543855269236.49056949550.2697889953320.667241982
1460.2914896417260.03849973139650.05586218611760.05256320780840.09017221159190.2246687712010.0968411389766-0.2621080715850.08034979386030.2241251956660.04020892173870.0608781740031-0.0427806850065-0.113454958534-0.07879339269530.892779788996-0.2180388556870.1618062227780.503405168139-0.05198633614340.30344458639177.184555972-18.9423010016323.235797762
1470.1885697555790.0758362334670.02164248883670.132972937294-0.05404028655520.229605988078-0.000142240903777-0.174352991888-0.07362543459570.250501941364-0.06586239150020.0102356423142-0.02633642986020.01652246099980.02780459328340.583130623281-0.1476680744020.1191108032090.2997919706920.04315198726690.268039259303174.838931991-38.9451523825301.419248173
1480.2961871472660.1265573238230.01184515411540.18827440554-0.003559948800850.140898572550.1094805345-0.00157465403589-0.05531066049840.191216447078-0.0506896123937-0.0492669678906-0.03934764091690.0088780820592-0.04445490903910.311582912301-0.0898796662405-0.0311618583720.1775510404930.04106724323430.35715844184218.708023803-27.6235251548263.968921107
1490.176066185718-0.08962036880560.1410655684890.146204873002-0.08442954881160.1742543546130.0183491007569-0.0202586348439-0.02916691686040.141754076042-0.0583044892843-0.131385811060.01638467205960.1211389208530.1044694079510.6500043867270.104080303983-0.2695330581050.3547771793790.1150208771730.608782981355239.301619526-85.3613074117279.563559975
1500.100083754463-0.04548772966380.06512766617620.0889213105679-0.05091090407570.04886192678440.03257750272420.09777956293140.128438303734-0.114509177019-0.07985521282360.0247265363945-0.20222220118-0.0676788788360.03442342872220.776793679895-0.003297298217350.08379867784930.5893183061060.2381404827761.31453122353198.92163692694.1004478666273.556405942
1510.2449303818390.03769500264890.02026021527580.005809776312940.004672501731590.1726430392920.0210266706925-0.2126216690520.1633811977940.2310631058620.0637748987710.0129938886408-0.232238747396-0.141248236752-0.05683045235770.7284637260290.02875229751570.127407929970.438406281232-0.1039306007080.393684801277168.0750451418.6333452404275.646768998
1520.0215523203452-0.109095865521-0.006412610536910.5574356022820.09722150479840.3893445348480.03784980821160.0063025292203-0.0853664711020.0998656888786-0.04986540737680.276078507395-0.0573236568896-0.382792078230.0127604168790.508881816316-0.03175530192050.3092618097430.70445902926-0.03569252416390.483449029678135.577322355-21.1173022851295.053462293
1530.2781565349630.05634264451550.01392760494420.0116204461434-0.003460369333350.1456908739560.01748118614650.01754825126060.0144027484824-0.0794443177815-0.002363182943930.182904681044-0.0160240161093-0.180665842005-0.003231218254590.659841011493-0.2393427850970.1323299045450.950119608210.1454416393661.20131545079172.09509869650.0791941775288.164114655
1540.207092309880.187262121034-0.04397639788960.484943343328-0.1398157572490.470264472059-0.000539234659021-0.01151765524230.0155152868501-0.0236638896107-0.066604525437-0.1302225411440.1291097871250.1749681864160.07203366820110.559932368093-0.03182461341930.007339648109370.439680885954-0.06683622483710.826016260413242.50584962540.2454703519292.842598064
1550.0640124108943-0.00212480300092-0.06405503841570.192172113114-0.208547392520.4196271020150.106862458004-0.07833574836010.06283591108050.2259178645240.116991708179-0.126811074439-0.09076904410360.0935928146524-0.1740494381830.595564484902-0.1807060375-0.1637003044190.4572058546580.02104459695950.599220869258239.248592479-20.8680134566289.409466072
1560.03997652092830.02290942902830.03512233391740.0426976782697-0.03394065166780.128733384284-0.00965711663904-0.0784718470166-0.08824166621380.10759604789-0.000264685417946-0.06338343754610.08237420748020.06059507368070.003659519951041.283195611230.163885764920.1389124732141.697794863810.2675066474211.64512619342294.83335983339.3921894565278.930823943
1570.1638050639060.007199032446820.01781564428490.2605144305280.1100955149060.1604526900940.0725473442854-0.0794081246993-0.02579817968130.154816461915-0.0572358454298-0.0294648649060.0559093510871-0.0142854042528-0.01852590173360.385999692986-0.09994214468640.01047469617570.2212159552080.05294724602170.257366585683201.85091516-25.5446972338274.289270282
1580.3635118533120.216371829930.05994550981550.456186086258-0.1678506906030.7050001391760.08727340342480.0192351392971-0.08309951888160.08843193235720.0705819876497-0.2702936142350.2512350506230.308724112084-0.1563240697830.6147405980540.00659595948534-0.1327530433960.6572855788770.1584379308941.12167561695324.774913079-15.3282311976187.095508614
精密化 TLSグループ
IDRefine-IDRefine TLS-IDSelection details
1X-RAY DIFFRACTION1chain 1
2X-RAY DIFFRACTION2chain 3
3X-RAY DIFFRACTION3chain 4
4X-RAY DIFFRACTION4chain j
5X-RAY DIFFRACTION5chain k
6X-RAY DIFFRACTION6chain l
7X-RAY DIFFRACTION7chain m
8X-RAY DIFFRACTION8chain n
9X-RAY DIFFRACTION9chain o
10X-RAY DIFFRACTION10chain p
11X-RAY DIFFRACTION11chain q
12X-RAY DIFFRACTION12chain r
13X-RAY DIFFRACTION13chain s
14X-RAY DIFFRACTION14chain t
15X-RAY DIFFRACTION15chain u
16X-RAY DIFFRACTION16chain v
17X-RAY DIFFRACTION17chain w
18X-RAY DIFFRACTION18chain x
19X-RAY DIFFRACTION19chain y
20X-RAY DIFFRACTION20chain z
21X-RAY DIFFRACTION21chain 0
22X-RAY DIFFRACTION22chain 2
23X-RAY DIFFRACTION23chain 5
24X-RAY DIFFRACTION24chain 6
25X-RAY DIFFRACTION25chain 7
26X-RAY DIFFRACTION26chain 8
27X-RAY DIFFRACTION27chain 9
28X-RAY DIFFRACTION28chain AA
29X-RAY DIFFRACTION29chain AB
30X-RAY DIFFRACTION30chain AC
31X-RAY DIFFRACTION31chain AD
32X-RAY DIFFRACTION32chain AE
33X-RAY DIFFRACTION33chain AF
34X-RAY DIFFRACTION34chain AG
35X-RAY DIFFRACTION35chain AH
36X-RAY DIFFRACTION36chain AI
37X-RAY DIFFRACTION37chain AJ
38X-RAY DIFFRACTION38chain AK
39X-RAY DIFFRACTION39chain AL
40X-RAY DIFFRACTION40chain AM
41X-RAY DIFFRACTION41chain AN
42X-RAY DIFFRACTION42chain AO
43X-RAY DIFFRACTION43chain AP
44X-RAY DIFFRACTION44chain AQ
45X-RAY DIFFRACTION45chain i
46X-RAY DIFFRACTION46chain AR
47X-RAY DIFFRACTION47chain AS
48X-RAY DIFFRACTION48chain AT
49X-RAY DIFFRACTION49chain CD
50X-RAY DIFFRACTION50chain CE
51X-RAY DIFFRACTION51chain CF
52X-RAY DIFFRACTION52chain CG
53X-RAY DIFFRACTION53chain CH
54X-RAY DIFFRACTION54chain CI
55X-RAY DIFFRACTION55chain CJ
56X-RAY DIFFRACTION56chain CK
57X-RAY DIFFRACTION57chain CL
58X-RAY DIFFRACTION58chain CM
59X-RAY DIFFRACTION59chain CN
60X-RAY DIFFRACTION60chain CO
61X-RAY DIFFRACTION61chain CP
62X-RAY DIFFRACTION62chain CQ
63X-RAY DIFFRACTION63chain CR
64X-RAY DIFFRACTION64chain CS
65X-RAY DIFFRACTION65chain CT
66X-RAY DIFFRACTION66chain CU
67X-RAY DIFFRACTION67chain CV
68X-RAY DIFFRACTION68chain CW
69X-RAY DIFFRACTION69chain CX
70X-RAY DIFFRACTION70chain CY
71X-RAY DIFFRACTION71chain CZ
72X-RAY DIFFRACTION72chain DA
73X-RAY DIFFRACTION73chain DB
74X-RAY DIFFRACTION74chain DC
75X-RAY DIFFRACTION75chain DD
76X-RAY DIFFRACTION76chain DE
77X-RAY DIFFRACTION77chain DF
78X-RAY DIFFRACTION78chain DG
79X-RAY DIFFRACTION79chain DH
80X-RAY DIFFRACTION80chain DI
81X-RAY DIFFRACTION81chain DJ
82X-RAY DIFFRACTION82chain DK
83X-RAY DIFFRACTION83chain DL
84X-RAY DIFFRACTION84chain DM
85X-RAY DIFFRACTION85chain DN
86X-RAY DIFFRACTION86chain DO
87X-RAY DIFFRACTION87chain DP
88X-RAY DIFFRACTION88chain DQ
89X-RAY DIFFRACTION89chain DR
90X-RAY DIFFRACTION90chain sM
91X-RAY DIFFRACTION91chain A
92X-RAY DIFFRACTION92chain B
93X-RAY DIFFRACTION93chain C
94X-RAY DIFFRACTION94chain D
95X-RAY DIFFRACTION95chain E
96X-RAY DIFFRACTION96chain F
97X-RAY DIFFRACTION97chain G
98X-RAY DIFFRACTION98chain H
99X-RAY DIFFRACTION99chain I
100X-RAY DIFFRACTION100chain J
101X-RAY DIFFRACTION101chain K
102X-RAY DIFFRACTION102chain L
103X-RAY DIFFRACTION103chain M
104X-RAY DIFFRACTION104chain N
105X-RAY DIFFRACTION105chain O
106X-RAY DIFFRACTION106chain P
107X-RAY DIFFRACTION107chain Q
108X-RAY DIFFRACTION108chain R
109X-RAY DIFFRACTION109chain S
110X-RAY DIFFRACTION110chain T
111X-RAY DIFFRACTION111chain U
112X-RAY DIFFRACTION112chain V
113X-RAY DIFFRACTION113chain W
114X-RAY DIFFRACTION114chain X
115X-RAY DIFFRACTION115chain Y
116X-RAY DIFFRACTION116chain Z
117X-RAY DIFFRACTION117chain a
118X-RAY DIFFRACTION118chain b
119X-RAY DIFFRACTION119chain c
120X-RAY DIFFRACTION120chain d
121X-RAY DIFFRACTION121chain e
122X-RAY DIFFRACTION122chain f
123X-RAY DIFFRACTION123chain g
124X-RAY DIFFRACTION124chain h
125X-RAY DIFFRACTION125chain s0
126X-RAY DIFFRACTION126chain s1
127X-RAY DIFFRACTION127chain s2
128X-RAY DIFFRACTION128chain s3
129X-RAY DIFFRACTION129chain s4
130X-RAY DIFFRACTION130chain s5
131X-RAY DIFFRACTION131chain s6
132X-RAY DIFFRACTION132chain s7
133X-RAY DIFFRACTION133chain s8
134X-RAY DIFFRACTION134chain s9
135X-RAY DIFFRACTION135chain c1
136X-RAY DIFFRACTION136chain c2
137X-RAY DIFFRACTION137chain c3
138X-RAY DIFFRACTION138chain c4
139X-RAY DIFFRACTION139chain c5
140X-RAY DIFFRACTION140chain c6
141X-RAY DIFFRACTION141chain c7
142X-RAY DIFFRACTION142chain c8
143X-RAY DIFFRACTION143chain c9
144X-RAY DIFFRACTION144chain c0
145X-RAY DIFFRACTION145chain d0
146X-RAY DIFFRACTION146chain d1
147X-RAY DIFFRACTION147chain d2
148X-RAY DIFFRACTION148chain d3
149X-RAY DIFFRACTION149chain d4
150X-RAY DIFFRACTION150chain d5
151X-RAY DIFFRACTION151chain d6
152X-RAY DIFFRACTION152chain d7
153X-RAY DIFFRACTION153chain d8
154X-RAY DIFFRACTION154chain d9
155X-RAY DIFFRACTION155chain e0
156X-RAY DIFFRACTION156chain e1
157X-RAY DIFFRACTION157chain sR
158X-RAY DIFFRACTION158chain p0

+
万見について

-
お知らせ

-
2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

-
2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbjlvh1.pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

+
2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

+
2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

+
2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

-
万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る