Entry | Database: PDB / ID: 5cgb |
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Title | Crystal structure of FimH in complex with heptyl alpha-D-septanoside |
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Components | Protein FimH |
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Keywords | SUGAR BINDING PROTEIN / UTI / lectin / urinary tract infection / type 1 fimbriae / pilus / inhibitor |
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Function / homology | Function and homology information
pilus tip / mechanosensory behavior / cell adhesion involved in single-species biofilm formation / pilus / cell-substrate adhesion / D-mannose binding / host cell membrane / cell adhesionSimilarity search - Function FimH, mannose-binding domain / FimH, mannose binding / Fimbrial-type adhesion domain / : / Fimbrial-type adhesion domain / Fimbrial protein / Fimbrial-type adhesion domain superfamily / Adhesion domain superfamily / Immunoglobulin-like / Sandwich / Mainly BetaSimilarity search - Domain/homology |
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Biological species | Escherichia coli K-12 (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.6 Å |
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Authors | Jakob, R.P. / Preston, R.P. / Zihlmann, P. / Fiege, B. / Sager, C.P. / Vannam, R. / Rabbani, S. / Zalewski, A. / Maier, T. / Ernst, B. / Peczuh, M. |
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Citation | Journal: Chem Sci / Year: 2018 Title: The price of flexibility - a case study on septanoses as pyranose mimetics. Authors: Sager, C.P. / Fiege, B. / Zihlmann, P. / Vannam, R. / Rabbani, S. / Jakob, R.P. / Preston, R.C. / Zalewski, A. / Maier, T. / Peczuh, M.W. / Ernst, B. |
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History | Deposition | Jul 9, 2015 | Deposition site: RCSB / Processing site: PDBE |
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Revision 1.0 | Jul 20, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Apr 7, 2021 | Group: Database references / Category: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.identifier_ORCID / _citation_author.name |
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Revision 1.2 | Jan 10, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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