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-Structure paper
Title | Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism. |
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Journal, issue, pages | Nucleic Acids Res., Vol. 50, Page 8867-8881, Year 2022 |
Publish date | Mar 8, 2022 (structure data deposition date) |
![]() | Satange, R. / Kao, S.H. / Chien, C.M. / Chou, S.H. / Lin, C.C. / Neidle, S. / Hou, M.H. |
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Methods | X-ray diffraction |
Resolution | 1.89 - 2.96 Å |
Structure data | ![]() PDB-7x6r: ![]() PDB-7x97: ![]() PDB-7x9f: ![]() PDB-7xdj: |
Chemicals | ![]() ChemComp-CO: ![]() ChemComp-QUI: ![]() ChemComp-HOH: ![]() ChemComp-ZN: ![]() ChemComp-K: ![]() ChemComp-CL: ![]() ChemComp-MN: ![]() ChemComp-MG: |
Source |
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![]() | DNA/ANTIBIOTIC / A:G mismatch / Single-strand DNA distortion / Actinomycin D / Echinomycin / mismatch binding drug / DNA / DNA-ANTIBIOTIC complex / C:G Watson-Crick base pair / Single-strand DNA twisting / G:C canonical DNA / Single-strand DNA twist / four-way junction / G:A mismatch / mismatch binding antibiotic |