EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Staphylococcus aureus Infections.
ジャーナル・号・ページ	Acs Infect Dis., Vol. 7, Page 3062-3076, Year 2021
掲載日	2017年2月12日 (構造データの登録日)
著者	Modi, G. / Marqus, G.M. / Vippila, M.R. / Gollapalli, D.R. / Kim, Y. / Manna, A.C. / Chacko, S. / Maltseva, N. / Wang, X. / Cullinane, R.T. ...Modi, G. / Marqus, G.M. / Vippila, M.R. / Gollapalli, D.R. / Kim, Y. / Manna, A.C. / Chacko, S. / Maltseva, N. / Wang, X. / Cullinane, R.T. / Zhang, Y. / Kotler, J.L.M. / Kuzmic, P. / Zhang, M. / Lawson, A.P. / Joachimiak, A. / Cheung, A. / Snider, B.B. / Rothstein, D.M. / Cuny, G.D. / Hedstrom, L.
リンク	Acs Infect Dis. / PubMed:34590817
手法	X線回折
解像度	2.34 - 2.75 Å
構造データ	PDB-5urs: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P178 手法: X-RAY DIFFRACTION / 解像度: 2.388 Å PDB-5uuv: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with a product IMP and the inhibitor P182 手法: X-RAY DIFFRACTION / 解像度: 2.75 Å PDB-5uuz: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P200 手法: X-RAY DIFFRACTION / 解像度: 2.496 Å PDB-7mtu: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P221 手法: X-RAY DIFFRACTION / 解像度: 2.34 Å PDB-7mtx: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P176 手法: X-RAY DIFFRACTION / 解像度: 2.44 Å
化合物	ChemComp-IMP: INOSINIC ACID / IMP ChemComp-8LA: N-[4-chloro-3-(alpha-D-ribofuranosyloxy)phenyl]-N'-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea ChemComp-K: Unknown entry / カリウムカチオン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-HOH: WATER ChemComp-8L1: N-{4-chloro-3-[4-(trifluoromethyl)-1,3-thiazol-2-yl]phenyl}-N'-(2-{3-[(1E)-N-hydroxyethanimidoyl]phenyl}propan-2-yl)urea ChemComp-8L4: 3-(2-{[(4-chlorophenyl)carbamoyl]amino}propan-2-yl)-N-hydroxybenzene-1-carboximidamide ChemComp-ZO7: N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-beta-D-arabinopyranosylamine ChemComp-ZO4: N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-beta-D-ribopyranosylamine
由来	bacillus anthracis (炭疽菌)
キーワード	OXIDOREDUCTASE / IMPDH / TIM barrel / delta CBS / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID / OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex