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Structure paper

TitleEpitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Journal, issue, pagesIscience, Vol. 27, Page 108976-108976, Year 2024
Publish dateFeb 27, 2020 (structure data deposition date)
AuthorsKim, Y. / Maltseva, N. / Tesar, C. / Jedrzejczak, R. / Endres, M. / Ma, H. / Dugan, H.L. / Stamper, C.T. / Chang, C. / Li, L. ...Kim, Y. / Maltseva, N. / Tesar, C. / Jedrzejczak, R. / Endres, M. / Ma, H. / Dugan, H.L. / Stamper, C.T. / Chang, C. / Li, L. / Changrob, S. / Zheng, N.Y. / Huang, M. / Ramanathan, A. / Wilson, P. / Michalska, K. / Joachimiak, A.
External linksIscience / PubMed:38327783
MethodsX-ray diffraction
Resolution1.5 - 2.9 Å
Structure data

PDB-6vyo:
Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6wkp:
Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-7n3c:
Crystal Structure of Human Fab S24-202 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-7n3d:
Crystal Structure of Human Fab S24-1564 in the complex with the N-terminal Domain of Nucleocapsid protein from SARS CoV-2
Method: X-RAY DIFFRACTION / Resolution: 1.53 Å

PDB-7str:
Crystal Structure of Human Fab S24-1063 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-7sts:
Crystal Structure of Human Fab S24-1379 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

PDB-7sue:
Crystal Structure of Human Fab S24-188 in the complex with the N-teminal Domain of Nucleocapsid protein from SARS CoV-2
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-CL:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-IOD:
IODIDE ION

ChemComp-PO4:
PHOSPHATE ION

Source
  • severe acute respiratory syndrome coronavirus 2
  • homo sapiens (human)
KeywordsVIRAL PROTEIN / CSGID / COVID-19 / RNA binding domain / nucleocapsid protein / nucleoprotein / Structural Genomics / Center for Structural Genomics of Infectious Diseases / RNA BINDING PROTEIN / SARS COV-2 / RNA-binding domain / SARS Coronavirus 2 / Human antibody Fab / VIRAL PROTEIN/IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM complex

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