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TitleCrystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P178
Journal, issue, pagesTo Be Published
Publish dateFeb 22, 2017 (structure data deposition date)
AuthorsMaltseva, N. / Kim, Y. / Mulligan, R. / Makowska-Grzyska, M. / Gu, M. / Gollapalli, D.R. / Hedstrom, L. / Joachimiak, A. / Anderson, W.F. / Center for Structural Genomics of Infectious Diseases (CSGID)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5uxe:
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P178
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-IMP:
INOSINIC ACID

ChemComp-8LA:
N-[4-chloro-3-(alpha-D-ribofuranosyloxy)phenyl]-N'-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea

ChemComp-K:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-FMT:
FORMIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • clostridium perfringens (bacteria)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / TIM barrel / IMPDH / CSGID / dehydrogenase / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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