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Structure paper

TitleStructures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 13692-, Year 2015
Publish dateOct 31, 2012 (structure data deposition date)
AuthorsCooper, C.D.O. / Newman, J.A. / Aitkenhead, H. / Allerston, C.K. / Gileadi, O.
External linksJ. Biol. Chem. / PubMed:25866208
MethodsX-ray diffraction
Resolution1.05 - 2.9 Å
Structure data

PDB-2ypr:
Crystal structure of the DNA binding ETS domain of human protein FEV
Method: X-RAY DIFFRACTION / Resolution: 2.64 Å

PDB-3zp5:
Crystal structure of the DNA binding ETS domain of the human protein FEV in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4avp:
Crystal structure of the DNA-binding domain of human ETV1.
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-4bnc:
Crystal structure of the DNA-binding domain of human ETV1 complexed with DNA
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-4co8:
Structure of the DNA binding ETS domain of human ETV4
Method: X-RAY DIFFRACTION / Resolution: 1.05 Å

PDB-4uno:
Crystal structure of the ETS domain of human ETV5 in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-4uuv:
Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CA:
Unknown entry

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / TRANSCRIPTION/DNA / TRANSCRIPTION-DNA COMPLEX / TRANSCRIPTIONAL ACTIVATION AND REPRESSION / DNA BINDING PROTEIN / E TWENTY-SIX / ERWING SARCOMA / PROSTATE CANCER / MELANOMA / GASTROINTESTINAL STROMAL TUMOUR / DNA-BINDING PROTEIN

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