EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro.
ジャーナル・号・ページ	Nat Commun, Vol. 16, Page 4288-4288, Year 2025
掲載日	2024年7月26日 (構造データの登録日)
著者	Su, H. / Chen, G. / Xie, H. / Li, W. / Xiong, M. / He, J. / Hu, H. / Zhao, W. / Shao, Q. / Li, M. ...Su, H. / Chen, G. / Xie, H. / Li, W. / Xiong, M. / He, J. / Hu, H. / Zhao, W. / Shao, Q. / Li, M. / Zhao, Q. / Xu, Y.
リンク	Nat Commun / PubMed:40341069
手法	X線回折
解像度	1.59 - 2.93 Å
構造データ	PDB-9iww: Crystal structure of the mouse RIP3 kinase domain in complexed with GSK'872 手法: X-RAY DIFFRACTION / 解像度: 1.93 Å PDB-9iwx: Crystal structure of the mouse RIP3 kinase domain(R69H) in complexed with GSK'872 手法: X-RAY DIFFRACTION / 解像度: 1.99 Å PDB-9iwy: Crystal structure of the mouse RIP3 kinase domain in complexed with LK01003 手法: X-RAY DIFFRACTION / 解像度: 2.52 Å PDB-9iwz: Crystal structure of the mouse RIP3 kinase domain in complexed with GSK'843 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-9ix0: Crystal structure of the mouse RIP3 kinase domain in complexed with GW'39B 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-9ix1: Crystal structure of the mouse RIP3 kinase domain in complexed with PP2 手法: X-RAY DIFFRACTION / 解像度: 2.31 Å PDB-9ix2: Crystal structure of the mouse RIP3 kinase domain in complexed with TAK-632 手法: X-RAY DIFFRACTION / 解像度: 2.39 Å PDB-9ix3: Crystal structure of the mouse RIP3 kinase domain in complexed with compound 18 手法: X-RAY DIFFRACTION / 解像度: 2.07 Å PDB-9lfu: Crystal structure of human RIP3 kinase domain complexed with LK01003 手法: X-RAY DIFFRACTION / 解像度: 2.93 Å PDB-9lfv: Crystal structure of mouse RIP3 kinase domain complexed with LK01004 手法: X-RAY DIFFRACTION / 解像度: 2.78 Å PDB-9lfw: Crystal structure of mouse RIP3 kinase domain(R69H) complexed with LK01003 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å
化合物	PDB-1d96: MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA ChemComp-HOH: WATER PDB-1d97: CHIRAL PHOSPHOROTHIOATE ANALOGUES OF B-DNA: THE CRYSTAL STRUCTURE OF RP-D(GP(S) CPGP(S)CPGP(S)C) ChemComp-ZOV: 3-(1,3-benzothiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine PDB-1d99: STRUCTURAL FEATURES AND HYDRATION OF A DODECAMER DUPLEX CONTAINING TWO C.A MISPAIRS ChemComp-PP2: 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE ChemComp-1SU: N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide PDB-1eaa: ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX PDB-1ejo: FAB FRAGMENT OF NEUTRALISING MONOCLONAL ANTIBODY 4C4 COMPLEXED WITH G-H LOOP FROM FMDV. PDB-1ejp: SOLUTION STRUCTURE OF THE SYNDECAN-4 WHOLE CYTOPLASMIC DOMAIN
由来	mus musculus (ハツカネズミ) homo sapiens (ヒト)
キーワード	TRANSFERASE / Mouse RIP3 kinase domain / inhibitor / complex / Human RIP3 kinase domain