EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	An Ion-Pair Induced Intermediate Complex Captured in Class D Carbapenemase Reveals Chloride Ion as a Janus Effector Modulating Activity
ジャーナル・号・ページ	Acs Cent. Sci., Year 2023
掲載日	2021年3月4日 (構造データの登録日)
著者	Zhou, Q. / Catalan, P. / Bell, H. / Baumann, P. / Cooke, R. / Evans, R. / Yang, J. / Zhang, Z. / Zappala, D. / Zhang, Y. ...Zhou, Q. / Catalan, P. / Bell, H. / Baumann, P. / Cooke, R. / Evans, R. / Yang, J. / Zhang, Z. / Zappala, D. / Zhang, Y. / Blackburn, G.M. / He, Y. / Jin, Y.
リンク	Acs Cent. Sci. / PubMedで検索
手法	X線回折
解像度	1.6 - 2.32 Å
構造データ	PDB-7nrj: OXA-48 with carbamylated Lys73 in complex with iodide ions at neutral pH 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-7o5n: OXA-48 with decarbamylated Lys73 in complex with avibactam at pH 8.0 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-7o5t: OXA-48 with carbamylated Lys73 in complex with bromide ions at neutral pH 手法: X-RAY DIFFRACTION / 解像度: 1.81 Å PDB-7o9n: OXA-48 with carbamylated Lys73 in complex with bicarbonate ions at neutral pH 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å PDB-7peh: Apo OXA-48 with fully carbamylated Lys73 at pH 7.5 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-7pei: OXA-48_E185A/R186A/R206A with carbamylated Lys73 in complex with chloride ions at neutral pH 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7pep: Crystal Structure of a Class D Carbapenemase Complexed with Hydrolyzed Imipenem 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-7pfn: Acetyllysine73-incorporated OXA-48 complexed with imipenem in both active and inactive acyl-enzyme intermediates 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7pgo: OXA-48_R250A with carbamylated Lys73 with bromide ions bound at neutral pH 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-7pse: Acetyllysine73-incorporated OXA-48 complexed with oxacillin 手法: X-RAY DIFFRACTION / 解像度: 2.32 Å PDB-7psf: Crystal Structure of a Class D Carbapenemase Complexed with Imipenem 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-7q14: Acetyllysine73-incorporated OXA-48 complexed with imipenem and bromide ions in both active and inactive acyl-enzyme intermediates 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
化合物	ChemComp-1BO: 1-BUTANOL / ブタノ-ル ChemComp-IOD: IODIDE ION / ヨ-ジド ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-HOH: WATER ChemComp-NXL: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide / 抗生剤, 阻害剤YM ChemComp-CL: Unknown entry / クロリド ChemComp-BR: BROMIDE ION / ブロミド ChemComp-BCT: BICARBONATE ION / オキシラトぎ酸 / pH緩衝剤YM ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-HIW: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca ChemComp-ID1: Imipenem / 抗生剤YM ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-1S6: (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb / 抗生剤YM
由来	klebsiella pneumoniae (肺炎桿菌)
キーワード	HYDROLASE / OXA / apo / iodide / Avibactam / chloride / bromide / Bicarbonate / interface mutant / Imipenem / Oxacillin / K73ALY