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Structure paper

TitleConservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans.
Journal, issue, pagesSci Rep, Vol. 12, Page 6065-6065, Year 2022
Publish dateFeb 16, 2022 (structure data deposition date)
AuthorsChowdhury, R. / Abboud, M.I. / Wiley, J. / Tumber, A. / Markolovic, S. / Schofield, C.J.
External linksSci Rep / PubMed:35410347
MethodsX-ray diffraction
Resolution1.641 - 2.45 Å
Structure data

PDB-7yxg:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2OG
Method: X-RAY DIFFRACTION / Resolution: 1.641 Å

PDB-7yxh:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and succinate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-7yxi:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and N-oxalylglycine (NOG)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-7yxj:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-7yxk:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and N-oxalyl-D-alanine (NODA)
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

PDB-7yxl:
Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and N-oxalyl-D-phenylalanine (NOFD)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SIN:
SUCCINIC ACID

ChemComp-OGA:
N-OXALYLGLYCINE / inhibitor*YM

ChemComp-SO4:
SULFATE ION

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PD2:
PYRIDINE-2,4-DICARBOXYLIC ACID

ChemComp-I78:
(2~{R})-2-(carboxycarbonylamino)propanoic acid

ChemComp-ACT:
ACETATE ION

ChemComp-NDF:
N-(CARBOXYCARBONYL)-D-PHENYLALANINE

Source
  • drosophila melanogaster (fruit fly)
KeywordsOXIDOREDUCTASE / NON-HEME / IRON / 2-OXOGLUTARATE / DIOXYGENASE / OXYGENASE / JMJC / JMJC DOMAIN / JMJC DOMAIN-CONTAINING PROTEIN 7 / JMJD7 / JMJC HYDROXYLASE / JMJC DEMETHYLASE / KDMS / POST-TRANSLATIONAL MODIFICATIONS / PTM / HYDROXYLATION / LYSYL HYDROXYLATION / DIMERISATION / TRANSLATION FACTOR / DEVELOPMENTALLY REGULATED GTP BINDING PROTEINS / DRG1 / DRG2 / TRAFAC GTPASE / HYPOXIA / NUCLEIC ACID- BINDING / METAL-BINDING / TRANSLATION / HELIX-LOOP-HELIX-BETA / DSBH / FACIAL TRIAD / DEVELOPMENT / CANCER / RIBOSOME BIOGENESIS

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