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Structure paper

TitleStructural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Journal, issue, pagesNat Commun, Vol. 8, Page 2070-2070, Year 2017
Publish dateNov 16, 2016 (structure data deposition date)
AuthorsMartin-Malpartida, P. / Batet, M. / Kaczmarska, Z. / Freier, R. / Gomes, T. / Aragon, E. / Zou, Y. / Wang, Q. / Xi, Q. / Ruiz, L. ...Martin-Malpartida, P. / Batet, M. / Kaczmarska, Z. / Freier, R. / Gomes, T. / Aragon, E. / Zou, Y. / Wang, Q. / Xi, Q. / Ruiz, L. / Vea, A. / Marquez, J.A. / Massague, J. / Macias, M.J.
External linksNat Commun / PubMed:29234012
MethodsX-ray diffraction
Resolution2 - 3.03 Å
Structure data

PDB-5mey:
Crystal structure of Smad4-MH1 bound to the GGCGC site.
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-5mez:
Crystal structure of Smad4-MH1 bound to the GGCT site.
Method: X-RAY DIFFRACTION / Resolution: 2.98 Å

PDB-5mf0:
Crystal structure of Smad4-MH1 bound to the GGCCG site.
Method: X-RAY DIFFRACTION / Resolution: 3.03 Å

PDB-5nm9:
Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site.
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

PDB-5od6:
Crystal structure of Smad3-MH1 bound to the GGCGC site.
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5odg:
Crystal structure of Smad3-MH1 bound to the GGCT site.
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • trichoplax adhaerens (invertebrata)
KeywordsTRANSCRIPTION / Smads / transcription factor / DNA complex

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