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Structure paper

TitleStructural and Histone Binding Ability Characterizations of Human PWWP Domains.
Journal, issue, pagesPlos One, Vol. 6, Page e18919-e18919, Year 2011
Publish dateAug 25, 2008 (structure data deposition date)
AuthorsWu, H. / Zeng, H. / Lam, R. / Tempel, W. / Amaya, M.F. / Xu, C. / Dombrovski, L. / Qiu, W. / Wang, Y. / Min, J.
External linksPlos One / PubMed:21720545
MethodsX-ray diffraction
Resolution1.3 - 2.82 Å
Structure data

PDB-3eae:
PWWP domain of human hepatoma-derived growth factor 2 (HDGF2)
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

PDB-3l42:
PWWP domain of human bromodomain and PHD finger containing protein 1
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-3llr:
Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3lyi:
PWWP Domain of Human Bromodomain-Containing Protein 1
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3mo8:
PWWP Domain of Human Bromodomain and PHD finger-containing protein 1 In Complex with Trimethylated H3K36 Peptide
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

PDB-3pfs:
PWWP Domain of Human Bromodomain and PHD finger-containing protein 3
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3pmi:
PWWP Domain of Human Mutated Melanoma-Associated Antigen 1
Method: X-RAY DIFFRACTION / Resolution: 2.82 Å

PDB-3qby:
Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-3qj6:
The crystal structure of PWWP domain of human Hepatoma-derived growth factor 2 in complex with H3K79me3 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3qkj:
The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-UNX:
Unknown entry

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-SO4:
SULFATE ION

ChemComp-OCS:
CYSTEINESULFONIC ACID

ChemComp-ZN:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER


ChemComp, No image

ChemComp-UNL:
Unknown ligand

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / human hepatoma-derived growth factor 2 / hepatoma-derived growth factor-related protein 2 / HDGF2 / Structural Genomics / Structural Genomics Consortium / SGC / Phosphoprotein / TRANSCRIPTION / transcription regulation / histone h3 acetylation / chromatin modification / Activator / Bromodomain / Chromatin regulator / DNA-binding / Metal-binding / Nucleus / Zinc-finger / TRANSFERASE / DNA methyltransferase / methylysine binding / Alternative promoter usage / Methyltransferase / Repressor / S-adenosyl-L-methionine / Peregrin / Protein BR140 / PROTEIN BINDING / PWWP Domain / PROTEIN BINDING/ NUCLEAR PROTEIN / histone / PROTEIN BINDING PROTEIN / PROTEIN BINDING- NUCLEAR PROTEIN complex / DNMT3B / METHYLTRANSFERASE 3 BETA

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